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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased colon adenoma incidence
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Accession:MP:0002044 term browser browse the term
Definition:greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the colon, occurring in a specific population in a given time period
Synonyms:exact_synonym: increased colonic adenoma incidence;   increased colonic adenomata incidence


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increased colon adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5402
    digestive/alimentary phenotype 78
      abnormal digestive system morphology 58
        increased alimentary system tumor incidence 28
          increased gastrointestinal tumor incidence 17
            increased intestinal adenoma incidence 14
              increased colon adenoma incidence 14
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          increased tumor incidence 166
            increased organ/body region tumor incidence 139
              increased alimentary system tumor incidence 28
                increased gastrointestinal tumor incidence 17
                  increased intestinal adenoma incidence 14
                    increased colon adenoma incidence 14
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