MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: abnormal homeostasis
Accession: MP:0001764
browse the term
Definition: anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the fluids and tissues
Synonyms: exact_synonym: abnormal homeostatic process; homeostasis abnormalities
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Myc
MYC proto-oncogene, bHLH transcription factor
IMP
RGD
PMID:22842522
RGD:7207891
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Cckar
cholecystokinin A receptor
IAGP
RGD
PMID:15178543
RGD:1625204
NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
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Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:24608905
RGD:11566051
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:24608905
RGD:11566051
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Esr2
estrogen receptor 2
IMP
RGD
PMID:29580824
RGD:38548925
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
compared to wild type
RGD
PMID:29580824
RGD:38548925
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Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
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Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
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Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
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Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
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Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
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Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
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Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:24608905
RGD:11566051
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
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Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:24608905
RGD:11566051
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Lepr
leptin receptor
treatment
IAGP
compared to treated
RGD
PMID:33568522
RGD:401965412
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Comt
catechol-O-methyltransferase
IDA
RGD
PMID:12535946
RGD:704422
NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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Lepr
leptin receptor
treatment
IAGP
compared to treated
RGD
PMID:33568522
RGD:401965412
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
IMP
Por
RGD
PMID:27856527
RGD:127285625
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i2em1Sage
nuclear receptor subfamily 1, group I, member 2; ZFN induced mutant1, Sage
IMP
Por
RGD
PMID:27856527
RGD:127285625
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Gper1
G protein-coupled estrogen receptor 1
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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Gper1em1Bj
G protein-coupled estrogen receptor 1; CRISPR/Cas 9 induced mutant 1, Bj
IMP
compared to wild type SS rat
RGD
PMID:30354811
RGD:39939000
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Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:29563343 PMID:34541380 PMID:34320241
RGD:150429980 , RGD:401976419 , RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:29563343 PMID:34541380 PMID:34320241
RGD:150429980 , RGD:401976419 , RGD:401976418
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F8
coagulation factor VIII
treatment
IMP
RGD
PMID:31899798
RGD:150520060
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
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F8em1Sage
coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage
treatment
IMP
RGD
PMID:31899798
RGD:150520060
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F8em1Mcwi
coagulation factor VIII, procoagulant component; CRISPR/Cas9 induced mutant1, Mcwi
treatment
IMP
RGD
PMID:31899798
RGD:150520060
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Slc6a4
solute carrier family 6 member 4
IMP
RGD
PMID:19246633
RGD:4889487
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Lep
leptin
IMP
RGD
PMID:22948215
RGD:12904911
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepem1Sage
leptin; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:22948215
RGD:12904911
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Slc11a2
solute carrier family 11 member 2
IAGP
RGD
PMID:9448300 PMID:14675167
RGD:729808 , RGD:1580428
NCBI chr 7:131,503,076...131,540,246
Ensembl chr 7:131,503,081...131,540,145
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Cebpa
CCAAT/enhancer binding protein alpha
IDA
RGD
PMID:12865412
RGD:704418
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cd36
CD36 molecule
IAGP
RGD
PMID:9916795
RGD:619666
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
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Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
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Lepr
leptin receptor
treatment
IAGP
RGD
PMID:33568522
RGD:401965412
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Gla
galactosidase, alpha
IMP
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Gla
galactosidase, alpha
IMP
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Klf5
KLF transcription factor 5
IMP
Syp, Gap43
RGD
PMID:32272873
RGD:45073134
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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Mir195
microRNA 195
IMP
Syp, Gap43
RGD
PMID:32272873
RGD:45073134
NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
treatment
IAGP
RGD
PMID:1127102
RGD:1354700
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt1a1j
UDP glucuronosyltransferase family 1 member A1, jaundice mutant
treatment
IAGP
RGD
PMID:1127102
RGD:1354700
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
induces
IMP
compared to standard diet
RGD
PMID:29656108
RGD:150520032
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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Cyp2j4em1Sage
cytochrome P450, family 2, subfamily j, polypeptide 4, ZFN induced mutant 1, Sage
induces
IMP
compared to standard diet
RGD
PMID:29656108
RGD:150520032
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Bmal1
basic helix-loop-helix ARNT like 1
sex_dimorphism
IMP
in male
RGD
PMID:32306766
RGD:155598602
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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Bmal1em1Mcwi
basic helix-loop-helix ARNT like 1;CRISPR/Cas9 induced mutant 1,Mcwi
sex_dimorphism
IMP
in male
RGD
PMID:32306766
RGD:155598602
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Btg2
BTG anti-proliferation factor 2
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Chi3l1
chitinase 3 like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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Chit1
chitinase 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Etnk2
ethanolamine kinase 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037
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Fmod
fibromodulin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,493,517...45,504,134
Ensembl chr13:45,493,517...45,504,133
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Gpr37l1
G protein-coupled receptor 37-like 1
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,598,574...46,605,421
Ensembl chr13:46,598,578...46,605,421
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Ipo9
importin 9
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673
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Lepr
leptin receptor
sexual_dimorphism treatment
IAGP
compared to BN compared to ad lib fed rats
RGD
PMID:20159938 PMID:11500530
RGD:7365117 , RGD:628581
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Leprfa
leptin receptor; fa mutant
sexual_dimorphism treatment
IAGP
compared to BN compared to ad lib fed rats
RGD
PMID:20159938 PMID:11500530
RGD:7365117 , RGD:628581
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Lgr6
leucine-rich repeat-containing G protein-coupled receptor 6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,424,382...46,544,074
Ensembl chr13:46,424,383...46,543,945
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Mybph
myosin binding protein H
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:45,653,156...45,660,893
Ensembl chr13:45,653,234...45,660,893
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
IMP
RGD
PMID:24722447
RGD:12910103
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Optc
opticin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237
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Plekha6
pleckstrin homology domain containing A6
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,614,740...44,754,951
Ensembl chr13:44,615,011...44,754,673
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Prelp
proline and arginine rich end leucine rich repeat protein
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
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Ptprv
protein tyrosine phosphatase, receptor type, V
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,548,125...46,569,148
Ensembl chr13:46,548,128...46,568,329
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Ren
renin
IAGP
RGD
PMID:23817491
RGD:12802368
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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Rnpep
arginyl aminopeptidase
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,699,458...46,717,829
Ensembl chr13:46,699,463...46,717,998
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Sox13
SRY-box transcription factor 13
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762
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Syt2
synaptotagmin 2
IAGP
RGD
PMID:23460292
RGD:12802369
NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859
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Hvcn1
hydrogen voltage-gated channel 1
IMP
RGD
PMID:31250553
RGD:14985213
NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
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Hvcn1em2Mcwi
hydrogen voltage-gated channel 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:31250553
RGD:14985213
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Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
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Gimap5
GTPase, IMAP family member 5
IAGP
RGD
PMID:17705691
RGD:2303768
NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
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Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:30733544
RGD:25823141
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:30733544
RGD:25823141
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Srebf1
sterol regulatory element binding transcription factor 1
IAGP
RGD
PMID:18071061
RGD:1643359
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srebf1_v2
sterol regulatory element binding factor 1, variant 2
IAGP
RGD
PMID:18071061
RGD:1643359
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Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
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Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
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Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
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Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
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Htr7
5-hydroxytryptamine receptor 7
IMP
in male
RGD
PMID:31125290
RGD:14696717
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
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Htr7em1Msu
5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu
IMP
in male
RGD
PMID:31125290
RGD:14696717
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
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Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP
compared to male wild-type
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
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Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Ren
renin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
G
Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
treatment
IMP
compared to Jcl:Wi and untreated
RGD
PMID:32231239
RGD:32716373
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
G
Cyp27b1em1Thka
cytochrome P450, family 27, subfamily b, polypeptide 1; CRISPR/Cas9 induced mutant 1, Thka
treatment
IMP
compared to Jcl:Wi and untreated
RGD
PMID:32231239
RGD:32716373
G
Vdr
vitamin D receptor
treatment
IMP
compared to Jcl:Wi and untreated
RGD
PMID:32231239
RGD:32716373
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
G
Vdrem1Thka
vitamin D receptor; CRISPR/Cas9 induced mutant 1, Thka
treatment
IMP
compared to Jcl:Wi and untreated
RGD
PMID:32231239
RGD:32716373
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:1561010
RGD:25823154
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:1561010
RGD:25823154
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Fmr1
fragile X messenger ribonucleoprotein 1
IMP
compared to wild type
RGD
PMID:35328827
RGD:405100966
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
G
Fmr1em1Sage
FMRP translational regulator 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
compared to wild type
RGD
PMID:35328827
RGD:405100966
G
Gla
galactosidase, alpha
IMP
compared to Wild type female
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to Wild type female
RGD
PMID:29979634
RGD:401976416
G
Htr7
5-hydroxytryptamine receptor 7
IMP
in male
RGD
PMID:31125290
RGD:14696717
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
G
Htr7em1Msu
5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu
IMP
in male
RGD
PMID:31125290
RGD:14696717
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:2022751 PMID:17303181
RGD:25823147 , RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:17303181 PMID:2022751
RGD:2292672 , RGD:25823147
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Tspo
translocator protein
induces
IMP
RGD
PMID:29074640
RGD:150429771
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
G
Tspoem1Vpl
translocator protein; ZFN induced mutant1, Vpl
induces
IMP
RGD
PMID:29074640
RGD:150429771
G
Tspoem2Vpl
translocator protein; ZFN induced mutant2, Vpl
induces
IMP
RGD
PMID:29074640
RGD:150429771
G
Aire
autoimmune regulator
IMP
RGD
PMID:29959280
RGD:38599145
NCBI chr20:10,636,058...10,651,060
Ensembl chr20:10,636,123...10,651,060
G
Aireem1Ang
autoimmune regulator; ZFN induced mutant1, Ang
IMP
RGD
PMID:29959280
RGD:38599145
G
Cd40
CD40 molecule
IMP
RGD
PMID:27692815
RGD:14398462
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd40em1Uthal
CD40 molecule; ZFN induced mutant 1, Uthal
IMP
RGD
PMID:27692815
RGD:14398462
G
Ets1
ETS proto-oncogene 1, transcription factor
induces
IAGP
compared to littermate
RGD
PMID:31932071
RGD:150429812
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
G
Ets1em1Mcwi
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
induces
IAGP
compared to littermate
RGD
PMID:31932071
RGD:150429812
G
Mmp2
matrix metallopeptidase 2
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp2em2Mcwi
matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
G
Crh
corticotropin releasing hormone
IDA
RGD
PMID:12450317
RGD:704424
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
G
Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
G
Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
G
Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
G
Cd36
CD36 molecule
IMP
RGD
PMID:11175782 PMID:14640889
RGD:68930 , RGD:1600636
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Apoa4
apolipoprotein A4
induces
IMP
compared to wild type
RGD
PMID:31303888
RGD:150429948
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
G
Apoa4em1Bcgen
apolipoprotein A4; TALEN induced mutant 1, Bcgn
induces
IMP
compared to wild type
RGD
PMID:31303888
RGD:150429948
G
Gck
glucokinase
IDA
RGD
PMID:10512368
RGD:2301945
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Gla
galactosidase, alpha
IMP
compared to Wild type males
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to Wild type males
RGD
PMID:29979634
RGD:401976416
G
Glp1r
glucagon-like peptide 1 receptor
NOT
IDA
RGD
PMID:12093887
RGD:625448
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
G
Ghsr
growth hormone secretagogue receptor
IMP
DNA:missense mutation:cds:nucleotide 1027
RGD
PMID:27129673
RGD:150520013
NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
G
Ghsrm1Mcwi
growth hormone secretagogue receptor; mutation 1, Medical College of Wisconsin
IMP
compared to wild type rats in response to ghrelin (CHEBI:75431)
RGD
PMID:27129673
RGD:150520013
G
Apoe
apolipoprotein E
IMP
RGD
PMID:30796231
RGD:150521536
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Atp7b
ATPase copper transporting beta
IAGP
RGD
PMID:17303181
RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
RGD
PMID:17303181
RGD:2292672
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
G
Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:29190650
RGD:151347176
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
G
Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:29190650
RGD:151347176
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Bckdk
branched chain ketoacid dehydrogenase kinase
IAGP
DNA:missense mutation:cds:G369E (rat)
RGD
PMID:27472223
RGD:39131293
NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
G
Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
G
Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
G
Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
G
Ghsr
growth hormone secretagogue receptor
IMP
RGD
PMID:19931319
RGD:12910109
NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
G
Pmch
pro-melanin-concentrating hormone
IMP
compared to wild-type
RGD
PMID:23555928 PMID:19934402
RGD:150429944 , RGD:150429945
NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
G
Pmchm1Hubr
pro-melanin-concentrating hormone; ENU induced mutant1, Hubr
IMP
compared to wild-type
RGD
PMID:23555928 PMID:19934402
RGD:150429944 , RGD:150429945
G
Bckdk
branched chain ketoacid dehydrogenase kinase
IAGP
DNA:missense mutation:cds:G369E (rat)
RGD
PMID:27472223
RGD:39131293
NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
G
Tg
thyroglobulin
IAGP
RGD
PMID:10760744
RGD:13605608
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
G
Tgrdw
thyroglobulin; rdw mutant
IAGP
RGD
PMID:10760744
RGD:13605608
G
Esr2
estrogen receptor 2
IMP
RGD
PMID:28520870
RGD:38548924
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
RGD
PMID:28520870
RGD:38548924
G
Kiss1
KiSS-1 metastasis-suppressor
IMP
RGD
PMID:25582792
RGD:10059342
NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612
G
Kiss1tm1Nips
KiSS-1 metastasis-suppressor; targeted mutant 1, Nips
IMP
RGD
PMID:25582792
RGD:10059342
G
Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
G
Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
G
Csf1r
colony stimulating factor 1 receptor
IMP
RGD
PMID:30249809
RGD:41404725
NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
G
Csf1rtm(EGFP)Tset
colony stimulating factor 1 receptor; target mutant, Tset
IMP
RGD
PMID:30249809
RGD:41404725
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Crh
corticotropin releasing hormone
IDA
RGD
PMID:12450317
RGD:704424
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
G
Esr2
estrogen receptor 2
IMP
RGD
PMID:29580824
RGD:38548925
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Esr2em1Soar
estrogen receptor 2; ZFN induced mutant 1, Soar
IMP
compared to wild type
RGD
PMID:29580824
RGD:38548925
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
IMP
compared to wild type
RGD
PMID:26077568
RGD:13800514
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
G
Hsd11b2em1Jmul
hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul
IMP
compared to wild type
RGD
PMID:26077568
RGD:13800514
G
Alb
albumin
IAGP
RGD
PMID:1690892
RGD:734959
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
G
Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:24608905
RGD:11566051
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
G
Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:24608905
RGD:11566051
G
F8
coagulation factor VIII
IMP
as compared to wild type Sprague Dawley
RGD
PMID:24931420
RGD:11530071
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F8em1Sage
coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:24931420
RGD:11530071
G
Gla
galactosidase, alpha
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Dhh
desert hedgehog signaling molecule
IMP
RGD
PMID:21062903
RGD:38548923
NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
G
Tspo
translocator protein
IMP
RGD
PMID:29074640
RGD:150429771
NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
G
Tspoem1Vpl
translocator protein; ZFN induced mutant1, Vpl
IMP
RGD
PMID:29074640
RGD:150429771
G
Tspoem2Vpl
translocator protein; ZFN induced mutant2, Vpl
IMP
RGD
PMID:29074640
RGD:150429771
G
Wwox
WW domain-containing oxidoreductase
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391
G
Wwoxlde
WW domain-containing oxidoreductase; lde mutant
IAGP
compared to wild type and heterozygotes
RGD
PMID:18676360
RGD:150429974
G
Tshr
thyroid stimulating hormone receptor
IMP
RGD
PMID:29507327
RGD:150521601
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
G
Tshrem1Mlit
thyroid stimulating hormone receptor; CRISPR/Cas9 induced mutant 1, Mlit
IMP
RGD
PMID:29507327
RGD:150521601
G
F8
coagulation factor VIII
IMP
as compared to wild type Sprague Dawley
RGD
PMID:24931420
RGD:11530071
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F8em1Sage
coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:24931420
RGD:11530071
G
Gla
galactosidase, alpha
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Angptl8
angiopoietin-like 8
induces
IMP
compared to wild type rats
RGD
PMID:30042156 PMID:30042156
RGD:38549347 , RGD:38549347
NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
G
Angptl8em1Kyo
angiopoietin-like 8; CRISPR/Cas9 induced mutant 1, Kyo
induces
IMP
compared to wild type rats
RGD
PMID:30042156 PMID:30042156
RGD:38549347 , RGD:38549347
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Htr7
5-hydroxytryptamine receptor 7
IMP
in male
RGD
PMID:31125290
RGD:14696717
NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
G
Htr7em1Msu
5-hydroxytryptamine receptor 7; CRISPR/Cas9 induced mutant 1, Msu
IMP
in male
RGD
PMID:31125290
RGD:14696717
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Tshr
thyroid stimulating hormone receptor
IMP
RGD
PMID:29507327
RGD:150521601
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
G
Tshrem1Mlit
thyroid stimulating hormone receptor; CRISPR/Cas9 induced mutant 1, Mlit
IMP
RGD
PMID:29507327
RGD:150521601
G
Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
G
Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
G
Il1rl2
interleukin 1 receptor-like 2
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
G
Il1rl2tm1(Myh6-cre)Mhzh
interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh
IMP
compared to Wild Type in cardiopulmonary bypass model
RGD
PMID:32048631
RGD:126925167
G
Bckdk
branched chain ketoacid dehydrogenase kinase
IAGP
DNA:missense mutation:cds:G369E (rat)
RGD
PMID:27472223
RGD:39131293
NCBI chr 1:182,515,335...182,520,007
Ensembl chr 1:182,515,327...182,536,633
G
Angptl8
angiopoietin-like 8
IMP
compared to wild type rats
RGD
PMID:30042156
RGD:38549347
NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
G
Angptl8em1Kyo
angiopoietin-like 8; CRISPR/Cas9 induced mutant 1, Kyo
IMP
compared to wild type rats
RGD
PMID:30042156
RGD:38549347
G
Cd40
CD40 molecule
IMP
RGD
PMID:27692815
RGD:14398462
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd40em1Uthal
CD40 molecule; ZFN induced mutant 1, Uthal
IMP
RGD
PMID:27692815
RGD:14398462
G
Htt
huntingtin
IMP
RGD
PMID:12620967
RGD:13452381
NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070
G
Lepr
leptin receptor
treatment
IAGP
RGD
PMID:33568522
RGD:401965412
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Pmch
pro-melanin-concentrating hormone
IMP
RGD
PMID:19934402
RGD:150429945
NCBI chr 7:22,511,934...22,513,250
Ensembl chr 7:22,511,934...22,513,250
G
Pmchm1Hubr
pro-melanin-concentrating hormone; ENU induced mutant1, Hubr
IMP
RGD
PMID:19934402
RGD:150429945
G
Abcc8
ATP binding cassette subfamily C member 8
IAGP
compared to wild type
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
IAGP
compared to wild type
RGD
PMID:30616503
RGD:150573710
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Gja8
gap junction protein, alpha 8
induces
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
induces
IAGP
RGD
PMID:27871290
RGD:150429989
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type and heterozygous
RGD
PMID:28177704
RGD:150521607
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type and heterozygous
RGD
PMID:28177704
RGD:150521607
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Gh1
growth hormone 1
IAGP
RGD
PMID:2752987 PMID:2152867
RGD:1578505 , RGD:1578506
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
G
Gh1sdr
IAGP
RGD
PMID:2152867 PMID:2752987
RGD:1578506 , RGD:1578505
G
Abcc8
ATP binding cassette subfamily C member 8
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
G
Wfs1
wolframin ER transmembrane glycoprotein
induces
IMP
RGD
PMID:29976929
RGD:150519890
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
G
Wfs1em1Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 1
induces
IMP
RGD
PMID:29976929
RGD:150519890
G
Fmr1
fragile X messenger ribonucleoprotein 1
IMP
compared to wild type
RGD
PMID:35328827
RGD:405100966
NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050
G
Fmr1em1Sage
FMRP translational regulator 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
compared to wild type
RGD
PMID:35328827
RGD:405100966
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEC/Tj;
RGD
PMID:11509115
RGD:1302456
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEC/Tj;
RGD
PMID:11509115
RGD:1302456
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Rab38
RAB38, member RAS oncogene family
IAGP
RGD
PMID:9250486
RGD:1302447
NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
G
Rab38ru
Rab38, member of RAS oncogene family, ruby allele
IAGP
RGD
PMID:9250486
RGD:1302447
G
Gh1
growth hormone 1
IAGP
RGD
PMID:2752987 PMID:2152867
RGD:1578505 , RGD:1578506
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
G
Gh1sdr
IAGP
RGD
PMID:2152867 PMID:2752987
RGD:1578506 , RGD:1578505
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Pax6
paired box 6
IAGP
DNA:frameshift mutation:cds:
RGD
PMID:21203536
RGD:8552339
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
G
Pax6Sey2
paired box gene 6, small eye mutation 2
IAGP
RGD
PMID:21203536
RGD:8552339
G
Slc6a4
solute carrier family 6 member 4
IMP
RGD
PMID:19246633
RGD:4889487
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Sod3
superoxide dismutase 3
onset
IMP
compared to SS/JrHsdMcwi in lung
RGD
PMID:31972339 PMID:21730301
RGD:150573712 , RGD:14369425
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
G
Sod3m1Mcwi
superoxide dismutase 3; mutation 1, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi in lung
RGD
PMID:31972339 PMID:21730301
RGD:150573712 , RGD:14369425
G
Angptl8
angiopoietin-like 8
IMP
compared to wild type rats
RGD
PMID:30042156
RGD:38549347
NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
G
Angptl8em1Kyo
angiopoietin-like 8; CRISPR/Cas9 induced mutant 1, Kyo
IMP
compared to wild type rats
RGD
PMID:30042156
RGD:38549347
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Scn9a
sodium voltage-gated channel alpha subunit 9
induces
IMP
RGD
PMID:31550995
RGD:150429745
NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516
G
Scn9a*tm1Amgn
sodium voltage-gated channel alpha subunit 9;ZFN induced target mutant1, Amgn
induces
IMP
RGD
PMID:31550995
RGD:150429745
G
Slc6a4
solute carrier family 6 member 4
IMP
compared to wild type littermate
RGD
PMID:18581099
RGD:4889490
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
G
Slc6a4m1Hubr
solute carrier family 6 member 4; ZFN induced mutant1, Hubr
IMP
compared to wild type littermate
RGD
PMID:18581099
RGD:4889490
G
Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
G
Mmp2
matrix metallopeptidase 2
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp2em2Mcwi
matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Add3
adducin 3
IMP
RGD
PMID:32029431
RGD:150340736
NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124
G
Cd247
Cd247 molecule
induced
IMP
RGD
PMID:24343121 PMID:24343121
RGD:13442481 , RGD:13442481
NCBI chr13:78,043,302...78,118,437
Ensembl chr13:78,043,307...78,122,263
G
Cd247em1Mcwi
Cd247 molecule; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
induced
IMP
RGD
PMID:24343121 PMID:24343121
RGD:13442481 , RGD:13442481
G
Nox4
NADPH oxidase 4
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
G
Nox4em2Mcwi
NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
induced
IMP
compared to SS/JrHsdMcwi
RGD
PMID:26644237 PMID:26644237
RGD:11085830 , RGD:11085830
G
Plekha7
pleckstrin homology domain containing A7
ameliorates
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
G
Plekha7em4Mcwi
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
ameliorates
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
G
Rag1
recombination activating 1
IMP
RGD
PMID:23364523
RGD:7207429
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
G
Rag1em1Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:23364523
RGD:7207429
G
Rag1em2Mcwi
recombination activating gene 1; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
as compared to SS-Rag1em1Mcwi on 4% NaCl diet
RGD
PMID:23364523
RGD:7207429
G
Sh2b3
SH2B adaptor protein 3
IMP
RGD
PMID:25776069
RGD:13442483
NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616
G
Sh2b3em1Mcwi
SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:25776069
RGD:13442483
G
Shc1
SHC adaptor protein 1
IMP
RGD
PMID:27270176
RGD:12792230
NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
G
Shc1em4Mcwi
SHC adaptor protein 1; ZFN induced mutant 4, Medical College of Wisconsin
IMP
RGD
PMID:27270176
RGD:12792230
G
Clcn6
chloride voltage-gated channel 6
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
G
Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
G
Ren
renin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
G
Tmem67
transmembrane protein 67
IAGP
RGD
PMID:11095650
RGD:1300514
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
treatment
IAGP
RGD
PMID:1127102
RGD:1354700
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a1j
UDP glucuronosyltransferase family 1 member A1, jaundice mutant
treatment
IAGP
RGD
PMID:1127102
RGD:1354700
G
Cd40
CD40 molecule
IMP
RGD
PMID:27692815
RGD:14398462
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
G
Cd40em1Uthal
CD40 molecule; ZFN induced mutant 1, Uthal
IMP
RGD
PMID:27692815
RGD:14398462
G
Clcn6
chloride voltage-gated channel 6
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
G
Mmp2
matrix metallopeptidase 2
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
G
Mmp2em2Mcwi
matrix metallopeptidase 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type SS
RGD
PMID:37643020
RGD:401827835
G
Nr2f2
nuclear receptor subfamily 2, group F, member 2
IMP
compared to SS/JrHsdMcw
RGD
PMID:25687237
RGD:10401852
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
G
Nr2f2em1Mcwi
nuclear receptor subfamily 2, group F, member 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcw
RGD
PMID:25687237
RGD:10401852
G
Plekha7
pleckstrin homology domain containing A7
ameliorates
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
G
Plekha7em4Mcwi
pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin
ameliorates
IMP
compared to wild type
RGD
PMID:25136115 PMID:25136115
RGD:11079199 , RGD:11079199
G
Ren
renin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
G
Clcn6
chloride voltage-gated channel 6
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
G
Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
G
Golgb1
golgin B1
IAGP
RGD
PMID:21851869
RGD:40902994
NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Ptpn22
protein tyrosine phosphatase, non-receptor type 22
IAGP
RGD
PMID:25505293
RGD:9835029
NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
G
Wfs1
wolframin ER transmembrane glycoprotein
onset
IMP
RGD
PMID:28860598
RGD:149735331
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
G
Wfs1em1Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 1
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Lepr
leptin receptor
IAGP
compared to heterozygous controls +/fa
RGD
PMID:11500530
RGD:628581
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprfa
leptin receptor; fa mutant
IAGP
compared to heterozygous controls +/fa
RGD
PMID:11500530
RGD:628581
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
G
Abcc8
ATP binding cassette subfamily C member 8
IAGP
compared to wild type
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
IAGP
compared to wild type
RGD
PMID:30616503
RGD:150573710
G
Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:28469073
RGD:12910100
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
G
Ldlrem1Sage
low density lipoprotein receptor; ZFN induced mutant 1, Sage
IMP
RGD
PMID:28469073
RGD:12910100
G
Lepr
leptin receptor
IMP
compared to SS/JrHsdMcwi
RGD
PMID:27225180 PMID:27465994
RGD:12910507 , RGD:12911217
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:27465994
RGD:12911217
G
Leprem3
leptin receptor; TALEN induced mutant 3
IMP
RGD
PMID:27225180
RGD:12910507
G
Pparg
peroxisome proliferator-activated receptor gamma
IAGP
compared to wild type rats
RGD
PMID:27381370
RGD:127285618
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppargm1Kyo
peroxisome proliferator-activated receptor gamma; ENU induced mutant 1, Kyo
IAGP
compared to wild type rats
RGD
PMID:27381370
RGD:127285618
G
Tbc1d4
TBC1 domain family, member 4
IMP
RGD
PMID:32053588 PMID:31034517
RGD:38596323 , RGD:38596332
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
G
Tbc1d4em1
TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,
IMP
RGD
PMID:32053588 PMID:31034517
RGD:38596323 , RGD:38596332
G
Wfs1
wolframin ER transmembrane glycoprotein
onset
IMP
RGD
PMID:28860598
RGD:149735331
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
G
Wfs1em1Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 1
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Wfs1em2Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 2
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Wfs1em3Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 3
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Ahr
aryl hydrocarbon receptor
sexual_dimorphism
IMP
females compared to Hsd:SD females
RGD
PMID:23859880
RGD:13204753
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Ahrem2Sage
aryl hydrocarbon receptor; ZFN induced mutant2, Sage
sexual_dimorphism
IMP
females compared to Hsd:SD females
RGD
PMID:23859880
RGD:13204753
G
Kit
KIT proto-oncogene receptor tyrosine kinase
IMP
RGD
PMID:7542218
RGD:12910748
NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
G
F8
coagulation factor VIII
treatment
IMP
RGD
PMID:31899798
RGD:150520060
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
G
F8em1Sage
coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage
treatment
IMP
RGD
PMID:31899798
RGD:150520060
G
F8em1Mcwi
coagulation factor VIII, procoagulant component; CRISPR/Cas9 induced mutant1, Mcwi
treatment
IMP
RGD
PMID:31899798
RGD:150520060
G
Lyst
lysosomal trafficking regulator
IAGP
in beige mutant rats
RGD
PMID:12638234
RGD:1302441
NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
G
Rab38
RAB38, member RAS oncogene family
IAGP
RGD
PMID:19897744 PMID:9250486
RGD:2324690 , RGD:1302447
NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
G
Rab38ru
Rab38, member of RAS oncogene family, ruby allele
IAGP
RGD
PMID:19897744 PMID:9250486
RGD:2324690 , RGD:1302447
G
Anks6
ankyrin repeat and sterile alpha motif domain containing 6
IAGP
compared to PKD
RGD
PMID:7933831
RGD:1300446
NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596
G
Anks6PKD
ankyrin repeat and sterile alpha motif domain containing 6, polycystic kidney disease
IAGP
compared to PKD
RGD
PMID:7933831
RGD:1300446
G
Cftr
CF transmembrane conductance regulator
IMP
RGD
PMID:24608905
RGD:11566051
NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
G
Cftrem1Sage
cystic fibrosis transmembrane conductance regulator; ZFN induced mutant 1 Sage
IMP
RGD
PMID:24608905
RGD:11566051
G
Col4a5
collagen type IV alpha 5 chain
IMP
RGD
PMID:34675305
RGD:329845598
NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692
G
Col4a5em1Matsu
collagen type IV alpha 5 chain; CRISPR/Cas9 induced mutant 1, Matsu
IMP
RGD
PMID:34675305
RGD:329845598
G
Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
G
Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
G
Gla
galactosidase, alpha
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:30278832 PMID:28746409
RGD:401960095 , RGD:401965413
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
IMP
compared to FHH
RGD
PMID:24722447
RGD:12910103
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
G
Nr4a1m1Mcwi
nuclear receptor subfamily 4, group A, member 1; mutation 1, Medical College of Wisconsin
IMP
compared to FHH
RGD
PMID:24722447
RGD:12910103
G
Ren
renin
IMP
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
RGD
PMID:21242461
RGD:7771614
G
Tmem67
transmembrane protein 67
IAGP
RGD
PMID:11095650 PMID:15052665
RGD:1300514 , RGD:15014788
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
G
Tmem67wpk
transmembrane protein 67; wpk mutant
IAGP
RGD
PMID:11095650 PMID:15052665
RGD:1300514 , RGD:15014788
G
Uox
urate oxidase
IMP
RGD
PMID:32368418
RGD:150521544
NCBI chr 2:235,486,867...235,523,053
Ensembl chr 2:235,440,619...235,523,029
G
Uoxem1Cya
urate oxidase; CRISPR/Cas9 induced mutant1, Cya
IMP
RGD
PMID:32368418
RGD:150521544
G
Uox
urate oxidase
IMP
RGD
PMID:32368418
RGD:150521544
NCBI chr 2:235,486,867...235,523,053
Ensembl chr 2:235,440,619...235,523,029
G
Uoxem1Cya
urate oxidase; CRISPR/Cas9 induced mutant1, Cya
IMP
RGD
PMID:32368418
RGD:150521544
G
Ednrb
endothelin receptor type B
IDA
RGD
PMID:16123229
RGD:1581859
NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
G
Myh7b
myosin heavy chain 7B
IMP
RGD
PMID:32207065
RGD:126925946
NCBI chr 3:144,076,911...144,122,714
Ensembl chr 3:144,098,190...144,122,084
G
Myh7bem1Blar
myosin heavy chain 7B; CRISPR/Cas9 induced mutant 1, Blar
IMP
RGD
PMID:32207065
RGD:126925946
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:30733544 PMID:17303181
RGD:25823141 , RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:17303181 PMID:30733544
RGD:2292672 , RGD:25823141
G
Lepr
leptin receptor
IMP IAGP
RGD
PMID:27225180 PMID:23154293
RGD:12910507 , RGD:13432147
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem3
leptin receptor; TALEN induced mutant 3
IMP
RGD
PMID:27225180
RGD:12910507
G
Leprfa
leptin receptor; fa mutant
IAGP
RGD
PMID:23154293
RGD:13432147
G
P2ry2
purinergic receptor P2Y2
IMP
RGD
PMID:19155635
RGD:2316657
NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
G
Ren
renin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
G
Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
IAGP
RGD
PMID:11832364
RGD:727991
NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
G
Gla
galactosidase, alpha
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Lamp2
lysosomal-associated membrane protein 2
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:28124283
RGD:13703118
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamp2em1
lysosomal-associated membrane protein 2; TALEN induced mutant1
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:28124283
RGD:13703118
G
P2ry2
purinergic receptor P2Y2
IMP
RGD
PMID:19155635
RGD:2316657
NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
G
Ahr
aryl hydrocarbon receptor
sexual_dimorphism
IMP
females compared to Hsd:SD females
RGD
PMID:23859880
RGD:13204753
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Ahrem2Sage
aryl hydrocarbon receptor; ZFN induced mutant2, Sage
sexual_dimorphism
IMP
females compared to Hsd:SD females
RGD
PMID:23859880
RGD:13204753
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:30733544
RGD:25823141
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:30733544
RGD:25823141
G
Gla
galactosidase, alpha
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Lamp2
lysosomal-associated membrane protein 2
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:28124283
RGD:13703118
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamp2em1
lysosomal-associated membrane protein 2; TALEN induced mutant1
IMP
RGD
PMID:28124283
RGD:13703118
G
Lepr
leptin receptor
IMP
RGD
PMID:27225180
RGD:12910507
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem3
leptin receptor; TALEN induced mutant 3
IMP
RGD
PMID:27225180
RGD:12910507
G
Abcc2
ATP binding cassette subfamily C member 2
IAGP
RGD
PMID:19525466
RGD:14985241
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Abcc2TR-
ATP binding cassette subfamily C member 2;transport deficient mutant ,
IAGP
RGD
PMID:19525466
RGD:14985241
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:30733544 PMID:17303181
RGD:25823141 , RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:17303181 PMID:30733544
RGD:2292672 , RGD:25823141
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
treatment
IAGP
compared to Gunn rats
RGD
PMID:16337205 PMID:1127102 PMID:15753292 PMID:20323028
RGD:13432067 , RGD:1354700 , RGD:1354702 , RGD:1354701
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a1j
UDP glucuronosyltransferase family 1 member A1, jaundice mutant
treatment
IAGP
compared to Gunn rats
RGD
PMID:16337205 PMID:1127102 PMID:20323028 PMID:15753292
RGD:13432067 , RGD:1354700 , RGD:1354701 , RGD:1354702
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Apoe
apolipoprotein E
IMP
RGD
PMID:30796231
RGD:150521536
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
G
Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
G
Lamp2
lysosomal-associated membrane protein 2
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:28124283
RGD:13703118
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamp2em1
lysosomal-associated membrane protein 2; TALEN induced mutant1
IMP
RGD
PMID:28124283
RGD:13703118
G
Lep
leptin
IMP
DNA:nonsense mutation:cds:
RGD
PMID:23800849
RGD:8549777
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lepm1Kyo
leptin; ENU induced mutant1, Kyo
IMP
RGD
PMID:23800849
RGD:8549777
G
Lepr
leptin receptor
disease_progression
IMP IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:27225180 PMID:10901178 PMID:28746409 PMID:30278832 PMID:27465994 PMID:26537785 PMID:23154293 More...
RGD:12910507 , RGD:401965414 , RGD:401965413 , RGD:401960095 , RGD:12911217 , RGD:12911216 , RGD:13432147
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
disease_progression
IMP
RGD
PMID:27465994
RGD:12911217
G
Leprem3
leptin receptor; TALEN induced mutant 3
IMP
RGD
PMID:27225180
RGD:12910507
G
Leprem4Lizh
leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh
IMP
compared to wild type littermate
RGD
PMID:26537785
RGD:12911216
G
Leprfa
leptin receptor; fa mutant
IAGP
RGD
PMID:23154293
RGD:13432147
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:24244710 PMID:23799078
RGD:12880447 , RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24244710
RGD:12880447
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
G
Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
IAGP
RGD
PMID:11832364
RGD:727991
NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
G
Nrg1
neuregulin 1
IMP
DNA:transposon insertion
RGD
PMID:21092742
RGD:10449008
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
G
Nrg1Tn(sb-T2/Bart3)2.183Mcwi
neuregulin 1; transposon insertion 2.183, Medical College of Wisconsin
IMP
compared to wild-type
RGD
PMID:21092742
RGD:10449008
G
Dmd
dystrophin
IMP
RGD
PMID:25310701
RGD:12880034
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
G
Dmdem1Ang
dystrophin; TALEN-induced mutant1, Ang
IMP
RGD
PMID:25310701
RGD:12880034
G
Anks6
ankyrin repeat and sterile alpha motif domain containing 6
IAGP
compared to PKD
RGD
PMID:7933831
RGD:1300446
NCBI chr 5:61,309,183...61,350,596
Ensembl chr 5:61,309,183...61,350,596
G
Anks6PKD
ankyrin repeat and sterile alpha motif domain containing 6, polycystic kidney disease
IAGP
compared to PKD
RGD
PMID:7933831
RGD:1300446
G
Col4a5
collagen type IV alpha 5 chain
IMP
RGD
PMID:34675305
RGD:329845598
NCBI chr X:105,118,762...105,322,699
Ensembl chr X:105,118,820...105,322,692
G
Col4a5em1Matsu
collagen type IV alpha 5 chain; CRISPR/Cas9 induced mutant 1, Matsu
IMP
RGD
PMID:34675305
RGD:329845598
G
Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
G
Fh
fumarate hydratase
IMP
RGD
PMID:27556703
RGD:13792708
NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
G
Fhem1
fumarate hydratase; TALEN induced mutant 1
IMP
RGD
PMID:27556703
RGD:13792708
G
Lepr
leptin receptor
IMP
RGD
PMID:27465994
RGD:12911217
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:27465994
RGD:12911217
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:24244710
RGD:12880447
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24244710
RGD:12880447
G
Ren
renin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
G
Renem1Mcwi
renin; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:21242461
RGD:7771614
G
Sod3
superoxide dismutase 3
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
G
Sod3m1Mcwi
superoxide dismutase 3; mutation 1, Medical College of Wisconsin
onset
IMP
compared to SS/JrHsdMcwi
RGD
PMID:31972339
RGD:150573712
G
Tmem67
transmembrane protein 67
IAGP
RGD
PMID:11095650
RGD:1300514
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
G
Tmem67wpk
transmembrane protein 67; wpk mutant
IAGP
RGD
PMID:11095650
RGD:1300514
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
IMP
in KO rat
RGD
PMID:30893315
RGD:126908018
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn1bem1Musc
cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc
IMP
at 9 weeks
RGD
PMID:30893315
RGD:126908018
G
Cdkn1bem4Musc
cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc
IMP
at 9 weeks
RGD
PMID:30893315
RGD:126908018
G
Esr1
estrogen receptor 1
IMP
RGD
PMID:24506075
RGD:8552987
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esr1em1Soar
estrogen receptor 1; ZFN induced mutant 1, Soar
IMP
RGD
PMID:24506075
RGD:8552987
G
Gck
glucokinase
IDA
overexpression sufficient to lower blood glucose significantly increased circulating FFA and TG levels (p<0.05)
RGD
PMID:10512368
RGD:2301945
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:28469073
RGD:12910100
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
G
Ldlrem1Sage
low density lipoprotein receptor; ZFN induced mutant 1, Sage
IMP
RGD
PMID:28469073
RGD:12910100
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2j4em1Sage
cytochrome P450, family 2, subfamily j, polypeptide 4, ZFN induced mutant 1, Sage
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
G
Insr
insulin receptor
induced
IMP
RGD
PMID:19017805
RGD:2314405
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
G
Lamp2
lysosomal-associated membrane protein 2
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:28124283
RGD:13703118
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamp2em1
lysosomal-associated membrane protein 2; TALEN induced mutant1
IMP
RGD
PMID:28124283
RGD:13703118
G
Lep
leptin
IMP
RGD
PMID:22948215
RGD:12904911
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lepem1Sage
leptin; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:22948215
RGD:12904911
G
Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:32710530 PMID:10901178 PMID:28746409
RGD:401960103 , RGD:401965414 , RGD:401965413
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type
RGD
PMID:28808062
RGD:150521563
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type
RGD
PMID:28808062
RGD:150521563
G
Trpc6
transient receptor potential cation channel, subfamily C, member 6
induces
IMP
compared to vehicle-treated wild type and control
RGD
PMID:29923767
RGD:149735534
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
G
Trpc6em1Mcwi
transient receptor potential cation channel, subfamily C, member 6; CRISPR/Cas9 induced mutant 1, Medical College of Wisconsin
induces
IMP
compared to vehicle-treated wild type and control
RGD
PMID:29923767
RGD:149735534
G
Wfs1
wolframin ER transmembrane glycoprotein
onset
IMP
RGD
PMID:28860598
RGD:149735331
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
G
Wfs1em1Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 1
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Lep
leptin
IMP
RGD
PMID:22948215
RGD:12904911
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lepem1Sage
leptin; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:22948215
RGD:12904911
G
Lepr
leptin receptor
IMP
RGD
PMID:26537785
RGD:12911216
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem4Lizh
leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh
IMP
compared to wild type littermate
RGD
PMID:26537785
RGD:12911216
G
Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
G
Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2j4em1Sage
cytochrome P450, family 2, subfamily j, polypeptide 4, ZFN induced mutant 1, Sage
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Insr
insulin receptor
induced
IMP
RGD
PMID:19017805
RGD:2314405
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
G
Lepr
leptin receptor
IMP IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:27465994 PMID:28746409
RGD:12911217 , RGD:401965413
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:27465994
RGD:12911217
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
G
Adora2b
adenosine A2B receptor
IMP
RGD
PMID:26385692
RGD:11533328
NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772
G
Adora2bem2Mcwi
adenosine A2B receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:26385692
RGD:11533328
G
Il36rn
interleukin 36 receptor antagonist
IMP
RGD
PMID:32048631
RGD:126925167
NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
G
Il36rntm1(Myh6-cre)Mhzh
interleukin 36 receptor antagonist; tm1, Mhzh
IMP
RGD
PMID:32048631
RGD:126925167
G
Apoe
apolipoprotein E
IMP
RGD
PMID:30796231
RGD:150521536
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
G
Lep
leptin
IMP
RGD
PMID:22948215
RGD:12904911
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lepem1Sage
leptin; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:22948215
RGD:12904911
G
Lepr
leptin receptor
IMP
RGD
PMID:26537785
RGD:12911216
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem4Lizh
leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh
IMP
compared to wild type littermate
RGD
PMID:26537785
RGD:12911216
G
Fabp4
fatty acid binding protein 4
IAGP
RGD
PMID:14724732
RGD:737686
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
G
Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:28469073
RGD:12910100
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
G
Ldlrem1Sage
low density lipoprotein receptor; ZFN induced mutant 1, Sage
IMP
RGD
PMID:28469073
RGD:12910100
G
Lepr
leptin receptor
IMP IAGP
compared to lean littermates
RGD
PMID:27465994 PMID:9032111
RGD:12911217 , RGD:11570540
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprcp
leptin receptor;corpulent
IAGP
compared to lean littermates
RGD
PMID:9032111
RGD:11570540
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:27465994
RGD:12911217
G
Leprfa
leptin receptor; fa mutant
IAGP
compared to lean littermates
RGD
PMID:9032111
RGD:11570540
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:21527895 PMID:24400148
RGD:6478803 , RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:21527895 PMID:24400148
RGD:6478803 , RGD:13825242
G
Esr1
estrogen receptor 1
IMP
RGD
PMID:24506075
RGD:8552987
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esr1em1Soar
estrogen receptor 1; ZFN induced mutant 1, Soar
IMP
RGD
PMID:24506075
RGD:8552987
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:28931751
RGD:38500204
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Il36rn
interleukin 36 receptor antagonist
IMP
RGD
PMID:32048631
RGD:126925167
NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
G
Il36rntm1(Myh6-cre)Mhzh
interleukin 36 receptor antagonist; tm1, Mhzh
IMP
RGD
PMID:32048631
RGD:126925167
G
Cyp27b1
cytochrome P450, family 27, subfamily b, polypeptide 1
treatment
IMP
compared to Jcl:Wi and treated
RGD
PMID:32231239
RGD:32716373
NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
G
Cyp27b1em1Thka
cytochrome P450, family 27, subfamily b, polypeptide 1; CRISPR/Cas9 induced mutant 1, Thka
treatment
IMP
compared to Jcl:Wi and treated
RGD
PMID:32231239
RGD:32716373
G
Vdr
vitamin D receptor
treatment
IMP
compared to Jcl:Wi and treated
RGD
PMID:32231239 PMID:32231239
RGD:32716373 , RGD:32716373
NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
G
Vdrem1Thka
vitamin D receptor; CRISPR/Cas9 induced mutant 1, Thka
treatment
IMP
compared to Jcl:Wi and treated
RGD
PMID:32231239
RGD:32716373
G
Vdrem2Thka
vitamin D receptor; CRISPR/Cas9 induced mutant 2, Thka
IMP
RGD
PMID:32231239
RGD:32716373
G
Abcc6
ATP binding cassette subfamily C member 6
IAGP
RGD
PMID:28111129
RGD:13792593
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
G
Abcc6em2Qlju
ATP-binding cassette, subfamily C (CFTR/MRP), member 6; zinc finger nuclease induced mutant 2, Qiaoli Li
IAGP
RGD
PMID:28111129
RGD:13792593
G
Dpp4
dipeptidylpeptidase 4
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
G
Dpp4DPPIV
dipeptidylpeptidase 4; DPPIV mutant
IAGP
compared to DA/Ztm
RGD
PMID:19327106
RGD:41408336
G
Gla
galactosidase, alpha
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Cdkn1b
cyclin-dependent kinase inhibitor 1B
IMP
at 4-6 weeks
RGD
PMID:30893315
RGD:126908018
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
G
Cdkn1bem1Musc
cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 1, Musc
IMP
at 4-6 weeks
RGD
PMID:30893315
RGD:126908018
G
Cdkn1bem4Musc
cyclin-dependent kinase inhibitor 1B; CRISPR/Cas9 induced mutant 4, Musc
IMP
at 4-6 weeks
RGD
PMID:30893315
RGD:126908018
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Lrrk2em1Sage
leucine-rich repeat kinase 2; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:23799078
RGD:13462048
G
Rarres2
retinoic acid receptor responder 2
sexual_dimorphism
IMP IAGP
compared to male knockout
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
NCBI chr 4:77,522,549...77,525,733
Ensembl chr 4:77,522,535...77,525,556
G
Rarres2em1Msu
retinoic acid receptor responder 2; CRISPR/Cas9 induced mutant 1, Msu
sexual_dimorphism
IMP IAGP
compared to male knockout
RGD
PMID:29906243 PMID:29906243
RGD:38596340 , RGD:38596340
G
Kcnj1
potassium inwardly-rectifying channel, subfamily J, member 1
IMP
RGD
PMID:23753405
RGD:13782272
NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
G
Kcnj1em1Kasu
potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu
IMP
RGD
PMID:23753405
RGD:13782272
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Tshr
thyroid stimulating hormone receptor
IMP
RGD
PMID:29507327
RGD:150521601
NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
G
Tshrem1Mlit
thyroid stimulating hormone receptor; CRISPR/Cas9 induced mutant 1, Mlit
IMP
RGD
PMID:29507327
RGD:150521601
G
Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
G
Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
G
Gck
glucokinase
IDA
overexpression sufficient to lower blood glucose significantly increased circulating FFA and TG levels (p<0.05)
RGD
PMID:10512368
RGD:2301945
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Lep
leptin
IMP
DNA:nonsense mutation:cds:
RGD
PMID:23800849
RGD:8549777
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
G
Lepm1Kyo
leptin; ENU induced mutant1, Kyo
IMP
RGD
PMID:23800849
RGD:8549777
G
Lepr
leptin receptor
treatment disease_progression
IMP IAGP
compared to ad lib fed rats
RGD
PMID:27225180 PMID:11500530 PMID:27465994 PMID:26537785
RGD:12910507 , RGD:628581 , RGD:12911217 , RGD:12911216
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
disease_progression
IMP
RGD
PMID:27465994
RGD:12911217
G
Leprem3
leptin receptor; TALEN induced mutant 3
IMP
RGD
PMID:27225180
RGD:12910507
G
Leprem4Lizh
leptin receptor; CRISPR/Cas9 induced mutant 4, Lizh
IMP
compared to wild type littermate
RGD
PMID:26537785
RGD:12911216
G
Leprfa
leptin receptor; fa mutant
treatment
IAGP
compared to ad lib fed rats
RGD
PMID:11500530
RGD:628581
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
G
Nr4a1
nuclear receptor subfamily 4, group A, member 1
IMP
compared to FHH
RGD
PMID:24722447
RGD:12910103
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
G
Nr4a1m1Mcwi
nuclear receptor subfamily 4, group A, member 1; mutation 1, Medical College of Wisconsin
IMP
compared to FHH
RGD
PMID:24722447
RGD:12910103
G
Il36rn
interleukin 36 receptor antagonist
IMP
RGD
PMID:32048631
RGD:126925167
NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016
G
Il36rntm1(Myh6-cre)Mhzh
interleukin 36 receptor antagonist; tm1, Mhzh
IMP
RGD
PMID:32048631
RGD:126925167
G
Arsb
arylsulfatase B
IAGP
RGD
PMID:21887218
RGD:39131283
NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
G
Gja8
gap junction protein, alpha 8
IAGP
RGD
PMID:27871290
RGD:150429989
NCBI chr 2:184,490,840...184,492,456
Ensembl chr 2:184,490,840...184,492,456
G
Gja8m1Cub
gap junction protein, alpha 8; mutant 1 Cub
IAGP
RGD
PMID:27871290
RGD:150429989
G
Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:34320241
RGD:401976418
G
Fah
fumarylacetoacetate hydrolase
IMP
after NTBC withdrawal in the drinking water
RGD
PMID:27510266
RGD:14398823
NCBI chr 1:138,548,830...138,571,599
Ensembl chr 1:138,548,834...138,571,505
G
Fahem15Dlli-/-
fumarylacetoacetate hydrolase; CRISPR/Cas9 induced mutant 15, Dlli
IMP
after NTBC withdrawal in the drinking water
RGD
PMID:27510266
RGD:14398823
G
Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
G
Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
G
Adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
IMP
RGD
PMID:32037220
RGD:38548917
NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494
G
Adamts16em1Bj
ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj
IMP
RGD
PMID:32037220
RGD:38548917
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2j4em1Sage
cytochrome P450, family 2, subfamily j, polypeptide 4, ZFN induced mutant 1, Sage
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
G
Dmd
dystrophin
IMP
RGD
PMID:25005781
RGD:11040981
NCBI chr X:47,272,324...49,504,219
Ensembl chr X:47,272,331...49,504,207
G
Dmdem1Kykn
dystrophin; CRISPR/Cas9 system induced mutant 1, Keitaro Yamanouchi
IMP
RGD
PMID:25005781
RGD:11040981
G
Lamp2
lysosomal-associated membrane protein 2
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:29720683
RGD:13703117
NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
G
Lamp2em1
lysosomal-associated membrane protein 2; TALEN induced mutant1
IMP
in hemizygote mutant male (LAMP2y/-)
RGD
PMID:29720683
RGD:13703117
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
RGD
PMID:28808062
RGD:150521563
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
RGD
PMID:28808062
RGD:150521563
G
Park7
Parkinsonism associated deglycase
IMP
RGD
PMID:24969022
RGD:13210569
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
G
Park7em1Sage
parkinson protein 7; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24969022
RGD:13210569
G
Pink1
PTEN induced kinase 1
IMP
RGD
PMID:24969022
RGD:13210569
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
G
Pink1em1Sage
PTEN induced putative kinase 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24969022
RGD:13210569
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
compared to Wild type
RGD
PMID:28177704
RGD:150521607
G
Tbc1d1
TBC1 domain family member 1
induces
IMP
RGD
PMID:28808062
RGD:150521563
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
G
Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
RGD
PMID:28808062
RGD:150521563
G
Slc9a6
solute carrier family 9 member A6
IMP
RGD
PMID:34928329
RGD:151664747
NCBI chr X:134,430,677...134,486,747
Ensembl chr X:134,420,756...134,485,375
G
Slc9a6 em1Moro
solute carrier family 9 member A6;CRISPR/Cas9 induced mutant1, Moro
IMP
RGD
PMID:34928329
RGD:151664747
G
Cd36
CD36 molecule
IMP
compared to SHR/OlaIpcv
RGD
PMID:14640889
RGD:1600636
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
G
Mc4r
melanocortin 4 receptor
IMP
RGD
PMID:24400148
RGD:13825242
NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719
G
Mc4rm1Hubr
melanocortin 4 receptor; ENU induced mutation 1, Hubr
IMP
RGD
PMID:24400148
RGD:13825242
G
Glp1r
glucagon-like peptide 1 receptor
IDA
RGD
PMID:12093887
RGD:625448
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
G
Lrrk2
leucine-rich repeat kinase 2
IMP
RGD
PMID:23799078
RGD:13462048
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
G
Abcc8
ATP binding cassette subfamily C member 8
induces
IMP
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
G
Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
induces
IMP
RGD
PMID:30616503
RGD:150573710
G
Cfb
complement factor B
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
G
Cfbem1Tja
complement factor B, ZFN induced mutant 1, Tja
IMP
compared to wild type SHR
RGD
PMID:28739975
RGD:127285403
G
Hsd11b2
hydroxysteroid 11-beta dehydrogenase 2
IMP
compared to wild type
RGD
PMID:26077568
RGD:13800514
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
G
Hsd11b2em1Jmul
hydroxysteroid 11-beta dehydrogenase 2; ZFN induced mutant1, Jmul
IMP
compared to wild type
RGD
PMID:26077568
RGD:13800514
G
Mir222
microRNA 222
treatment
IMP
associated with polycystic ovary syndrome;
RGD
PMID:33230470
RGD:151893462
NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
G
Zbtb16
zinc finger and BTB domain containing 16
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
G
Zbtb16em1Ipcv
zinc finger and BTB domain containing 16; TALEN induced mutant 1, Ipcv
IMP
compared to wild type SHR/OlaIpcv;
RGD
PMID:28396530
RGD:150340623
G
Atp7b
ATPase copper transporting beta
IAGP
RGD
PMID:17303181
RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
G
Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
RGD
PMID:17303181
RGD:2292672
G
Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:28469073
RGD:12910100
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
G
Ldlrem1Sage
low density lipoprotein receptor; ZFN induced mutant 1, Sage
IMP
RGD
PMID:28469073
RGD:12910100
G
Atp7b
ATPase copper transporting beta
IAGP
compared to LEA/Hok
RGD
PMID:8291609 PMID:17303181 PMID:30733544 PMID:1561010
RGD:15036817 , RGD:2292672 , RGD:25823141 , RGD:25823154
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
compared to LEA/Hok
RGD
PMID:17303181 PMID:30733544 PMID:8291609 PMID:1561010
RGD:2292672 , RGD:25823141 , RGD:15036817 , RGD:25823154
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Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:27378433
RGD:12910104
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Ldlrem1
low density lipoprotein receptor; ZFN induced mutant 1
IMP
RGD
PMID:27378433
RGD:12910104
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Abcc8
ATP binding cassette subfamily C member 8
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
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Cp
ceruloplasmin
IMP
RGD
PMID:31560858
RGD:38549582
NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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Cpem1Ang
ceruloplasmin; CRISPR/Cas9 induced mutant1, Ang
IMP
RGD
PMID:31560858
RGD:38549582
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Atp7b
ATPase copper transporting beta
IAGP
RGD
PMID:17303181
RGD:2292672
NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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Atp7bhts
ATPase copper transporting beta; hepatitis
IAGP
RGD
PMID:17303181
RGD:2292672
G
Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
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Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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Cyp2j4em1Sage
cytochrome P450, family 2, subfamily j, polypeptide 4, ZFN induced mutant 1, Sage
induces
IMP
compared to wild type
RGD
PMID:29656108
RGD:150520032
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Ldlr
low density lipoprotein receptor
IMP
RGD
PMID:28469073
RGD:12910100
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Ldlrem1Sage
low density lipoprotein receptor; ZFN induced mutant 1, Sage
IMP
RGD
PMID:28469073
RGD:12910100
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Lep
leptin
IMP
DNA:nonsense mutation:cds:
RGD
PMID:23800849
RGD:8549777
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepm1Kyo
leptin; ENU induced mutant1, Kyo
IMP
RGD
PMID:23800849
RGD:8549777
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Pparg
peroxisome proliferator-activated receptor gamma
IAGP
RGD
PMID:27381370
RGD:127285618
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargm1Kyo
peroxisome proliferator-activated receptor gamma; ENU induced mutant 1, Kyo
IAGP
RGD
PMID:27381370
RGD:127285618
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Grm2
glutamate metabotropic receptor 2
IMP
knock-out compared to wild-type rats
RGD
PMID:30283001
RGD:38501063
NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
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Grm2em1
glutamate metabotropic receptor 2; endonuclease induced mutant 1
IMP
KO compared to wild-type rats
RGD
PMID:30283001
RGD:38501063
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Bscl2
BSCL2 lipid droplet biogenesis associated, seipin
IMP
RGD
PMID:25934999
RGD:11085488
NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421
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Bscl2m1Kyo
BSCL2, seipin lipid droplet biogenesis associated; ENU induced mutant1, Kyo
IMP
RGD
PMID:25934999
RGD:11085488
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Pink1
PTEN induced kinase 1
onset
IMP
compared to LEH
RGD
PMID:25421206
RGD:11560775
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Pink1em1Sage
PTEN induced putative kinase 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
onset
IMP
compared to LEH
RGD
PMID:25421206
RGD:11560775
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Tbc1d1
TBC1 domain family member 1
induces
IMP
RGD
PMID:28808062
RGD:150521563
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
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Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
RGD
PMID:28808062
RGD:150521563
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F8
coagulation factor VIII
IMP
as compared to wild type Sprague Dawley
RGD
PMID:24931420
RGD:11530071
NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857
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F8em1Sage
coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage
IMP
RGD
PMID:24931420
RGD:11530071
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Abcg5
ATP binding cassette subfamily G member 5
IAGP
DNA:missense mutation: p.G583C , 1757G>T (rat)
RGD
PMID:16026620
RGD:1598659
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Slc6a4
solute carrier family 6 member 4
IMP
RGD
PMID:18581099
RGD:4889490
NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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Slc6a4m1Hubr
solute carrier family 6 member 4; ZFN induced mutant1, Hubr
IMP
RGD
PMID:18581099
RGD:4889490
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Park7
Parkinsonism associated deglycase
IMP
RGD
PMID:24969022
RGD:13210569
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Park7em1Sage
parkinson protein 7; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24969022
RGD:13210569
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Pink1
PTEN induced kinase 1
IMP
RGD
PMID:24969022
RGD:13210569
NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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Pink1em1Sage
PTEN induced putative kinase 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs
IMP
RGD
PMID:24969022
RGD:13210569
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Abcc8
ATP binding cassette subfamily C member 8
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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Abcc8em1Cgen
ATP binding cassette subfamily C member 8; TALEN induced mutant 1, Cgen
IMP
compared to wild type
RGD
PMID:30616503
RGD:150573710
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Tbc1d1
TBC1 domain family member 1
induces
IMP
RGD
PMID:28808062
RGD:150521563
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
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Tbc1d1Tn(sb)1Fkh
TBC1 domain family member 1; Sleeping Beauty induced mutant 1, Fkh
induces
IMP
RGD
PMID:28808062
RGD:150521563
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Tg
thyroglobulin
IAGP
RGD
PMID:10760744
RGD:13605608
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tgrdw
thyroglobulin; rdw mutant
IAGP
RGD
PMID:10760744
RGD:13605608
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Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:30278832 PMID:10901178 PMID:28746409
RGD:401960095 , RGD:401965414 , RGD:401965413
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Gla
galactosidase, alpha
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
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Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to Wild type
RGD
PMID:29979634
RGD:401976416
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Gla
galactosidase, alpha
onset
IMP
compared to Wild type males
RGD
PMID:29979634
RGD:401976416
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
onset
IMP
compared to Wild type males
RGD
PMID:29979634
RGD:401976416
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Ptpn22
protein tyrosine phosphatase, non-receptor type 22
IAGP
RGD
PMID:25505293
RGD:9835029
NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
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Wfs1
wolframin ER transmembrane glycoprotein
onset
IMP
RGD
PMID:28860598
RGD:149735331
NCBI chr14:73,810,478...73,834,993
Ensembl chr14:73,810,404...73,835,602
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Wfs1em1Ptsn
wolframin ER transmembrane glycoprotein; ZFN induced mutant 1
onset
IMP
RGD
PMID:28860598
RGD:149735331
G
Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:30278832
RGD:401960095
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Lepr
leptin receptor
IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:30278832 PMID:28746409
RGD:401960095 , RGD:401965413
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Trpc6
transient receptor potential cation channel, subfamily C, member 6
induces
IMP
compared to vehicle-treated control
RGD
PMID:29923767
RGD:149735534
NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092
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Trpc6em1Mcwi
transient receptor potential cation channel, subfamily C, member 6; CRISPR/Cas9 induced mutant 1, Medical College of Wisconsin
induces
IMP
compared to vehicle-treated control
RGD
PMID:29923767
RGD:149735534
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Tmem67
transmembrane protein 67
IAGP
RGD
PMID:15052665 PMID:11095650
RGD:15014788 , RGD:1300514
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
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Tmem67wpk
transmembrane protein 67; wpk mutant
IAGP
RGD
PMID:15052665 PMID:11095650
RGD:15014788 , RGD:1300514
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Actr3
actin related protein 3
IAGP
DNA:missense mutation:cds:p.L111F
RGD
PMID:18064521
RGD:2292230
NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124
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Adamts16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
NCBI chr 1:32,430,436...32,562,481
Ensembl chr 1:32,430,436...32,560,494
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Adamts16em1Bj
ADAM metallopeptidase with thrombospondin type 1 motif, 16; ZFN mutant1,Bj
IMP
As compared to SS parents
RGD
PMID:23185005
RGD:9685162
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Agtrap
angiotensin II receptor-associated protein
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,507,427...158,519,036
Ensembl chr 5:158,508,749...158,519,036
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Ctns
cystinosin, lysosomal cystine transporter
IMP
RGD
PMID:35695380
RGD:155630629
NCBI chr10:57,801,551...57,817,213
Ensembl chr10:57,801,456...57,817,120
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Lepr
leptin receptor
IMP IAGP
DNA:mutations:cds: : (rat)
RGD
PMID:27465994 PMID:10901178
RGD:12911217 , RGD:401965414
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:27465994
RGD:12911217
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Mthfr
methylenetetrahydrofolate reductase
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Ndufc2
NADH:ubiquinone oxidoreductase subunit C2
IMP
DNA:deletion:exon1:heterozygous 107 bp deletion
RGD
PMID:26888427
RGD:11040458
NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
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Ndufc2em2Mcwi
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:26888427
RGD:11040458
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Nppb
natriuretic peptide B
IMP
RGD
PMID:26063669
RGD:12910116
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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Nppbem2Mcwi
natriuretic peptide B; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:26063669
RGD:12910116
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Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
IMP
as compared to the wild-type
RGD
PMID:24006081
RGD:8662415
NCBI chr 5:158,340,674...158,367,581
Ensembl chr 5:158,340,490...158,367,620
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Rab38
RAB38, member RAS oncogene family
IAGP
compared to FHH-Tg(CAG-Rab38)1Mcwi, FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi
RGD
PMID:23291471
RGD:13782139
NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924
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Rab38em1Mcwi
RAB38, member RAS oncogene family; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IAGP
compared to FHH-Tg(CAG-Rab38)1Mcwi, FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi
RGD
PMID:23291471
RGD:13782139
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Resp18
regulated endocrine-specific protein 18
IMP
RGD
PMID:29570433
RGD:14348960
NCBI chr 9:76,765,179...76,771,824
Ensembl chr 9:76,764,590...76,778,722
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Resp18em2Mcwi
regulated endocrine-specific protein 18; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:29570433
RGD:14348960
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Tmem67
transmembrane protein 67
IAGP
RGD
PMID:11095650
RGD:1300514
NCBI chr 5:25,536,458...25,589,378
Ensembl chr 5:25,536,458...25,589,334
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Alms1
ALMS1, centrosome and basal body associated protein
induces
IMP
RGD
PMID:30385718
RGD:151361229
NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
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Alms1em1Mcwi
Alstrom syndrome 1 homolog (human); zinc finger nuclease induced mutant 1, Medical College of Wisconsin
induces
IMP
RGD
PMID:30385718
RGD:151361229
G
Lepr
leptin receptor
IMP
RGD
PMID:27465994
RGD:12911217
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
G
Leprem2Mcwi
leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin
IMP
RGD
PMID:27465994
RGD:12911217
G
Pparg
peroxisome proliferator-activated receptor gamma
induces
IAGP
compared to wild type rats
RGD
PMID:27381370
RGD:127285618
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppargm1Kyo
peroxisome proliferator-activated receptor gamma; ENU induced mutant 1, Kyo
induces
IAGP
compared to wild type rats
RGD
PMID:27381370
RGD:127285618
G
Tbc1d4
TBC1 domain family, member 4
IMP
RGD
PMID:32053588 PMID:31034517
RGD:38596323 , RGD:38596332
NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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Tbc1d4em1
TBC1 domain family, member 4; CRISPR/Cas9 system induced mutant 1,
IMP
RGD
PMID:32053588 PMID:31034517
RGD:38596323 , RGD:38596332
G
Gla
galactosidase, alpha
IMP
compared to wild type
RGD
PMID:34541380
RGD:401976419
NCBI chr X:97,769,227...97,780,646
Ensembl chr X:97,768,996...97,780,664
G
Glaem2Mcwi
galactosidase, alpha; CRISPR/Cas9 system induced mutant 2, Medical College of Wisconsin
IMP
compared to wild type
RGD
PMID:34541380
RGD:401976419
G
Kcnj16
potassium inwardly-rectifying channel, subfamily J, member 16
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
G
Kcnj16em1Mcwi
potassium inwardly-rectifying channel, subfamily J, member 16; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
IMP
compared to SS/JrHsdMcwi
RGD
PMID:30605394
RGD:38500203
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