ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G1/S transition of mitotic cell cycle
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Accession:GO:2000045 term browser browse the term
Definition:Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
Comment:Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.


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regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bid BH3 interacting domain death agonist GBrowse link 4 157,296,383 157,318,481 RGD:1600115
RGD:1624291
G Ccnd1 cyclin D1 GBrowse link 1 205,357,235 205,366,757 RGD:1624291
G E2f1 E2F transcription factor 1 GBrowse link 3 145,032,489 145,043,729 RGD:1600115
RGD:1624291
G Ecd ecdysoneless homolog (Drosophila) RGD:1600115
RGD:1624291
G Id2 inhibitor of DNA binding 2 GBrowse link 6 42,781,476 42,783,307 RGD:1600115
RGD:1624291
G Ino80 INO80 complex subunit GBrowse link 3 105,898,279 105,979,698 RGD:1600115
RGD:1624291
G Pdpn podoplanin GBrowse link 5 162,142,251 162,175,921 RGD:1600115
RGD:1624291
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link 9 83,412,797 83,429,039 RGD:1600115
RGD:1624291
G Plk5 polo-like kinase 5 GBrowse link 7 10,858,118 10,866,430 RGD:1600115
RGD:1624291
G Ptpla protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a GBrowse link 17 88,239,568 88,253,571 RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link 4 160,843,699 160,868,856 RGD:1600115
RGD:1624291
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 GBrowse link 11 81,225,720 81,259,934 RGD:1600115
RGD:1624291
G Tcf3 transcription factor 3 GBrowse link 7 10,791,311 10,813,613 RGD:1600115
RGD:1624291
G Tjp3 tight junction protein 3 GBrowse link 7 9,917,359 9,930,081 RGD:1600115
RGD:1624291
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Casp2 caspase 2 GBrowse link 4 70,029,728 70,047,164 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link 20 7,376,325 7,386,778 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link 7 32,504,279 32,517,581 RGD:1600115
RGD:1624291
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 56,996,694 57,020,926 RGD:1600115
RGD:1624291
G Muc1 mucin 1, cell surface associated GBrowse link 2 181,399,482 181,403,640 RGD:1624291
G Pcbp4 poly(rC) binding protein 4 GBrowse link 8 111,597,539 111,607,775 RGD:1624291
G Pidd1 p53-induced death domain protein 1 GBrowse link 1 201,626,042 201,631,182 RGD:1624291
G Pml promyelocytic leukemia GBrowse link 8 62,020,438 62,051,927 RGD:1600115
RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link 6 135,204,405 135,299,068 RGD:1600115
RGD:1624291
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link 13 48,070,488 48,090,682 RGD:1624291
G Rbm38 RNA binding motif protein 38 GBrowse link 3 163,885,488 163,898,314 RGD:1600115
RGD:1624291
G Sox4 SRY (sex determining region Y)-box 4 GBrowse link 17 42,172,863 42,177,590 RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1624291
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 GBrowse link 1 205,357,235 205,366,757 RGD:1600115
RGD:1624291
G Dgkz diacylglycerol kinase zeta GBrowse link 3 76,312,721 76,342,603 RGD:1600115
RGD:1624291
G Fbxo31 F-box protein 31 GBrowse link 19 51,836,918 51,837,223 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 GBrowse link 9 86,143,324 86,273,766 RGD:1624291
G LOC100910954 cellular tumor antigen p53-like RGD:1600115
G LOC498414 LRRGT00197 RGD:1600115
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link 13 48,070,488 48,090,682 RGD:1624291
G Rfwd3 ring finger and WD repeat domain 3 GBrowse link 19 41,190,144 41,222,888 RGD:1624291
G Rpa2 replication protein A2 GBrowse link 5 152,369,550 152,380,370 RGD:1624291
G Rps27l ribosomal protein S27-like RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1600115
G Tp73 tumor protein p73 GBrowse link 5 170,848,979 171,078,739 RGD:1600115
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link 13 12,730,736 12,905,108 RGD:1600115
RGD:1624291
G Brd7 bromodomain containing 7 GBrowse link 19 20,019,637 20,048,264 RGD:1600115
RGD:1624291
G Btn2a2 butyrophilin, subfamily 2, member A2 GBrowse link 17 48,823,679 48,834,495 RGD:1624291
G Cdc73 cell division cycle 73 GBrowse link 13 57,441,674 57,534,385 RGD:1600115
RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link 5 108,939,669 108,945,293 RGD:1600115
RGD:1624291
G Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 GBrowse link 9 73,731,542 73,736,764 RGD:1624291
G Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 RGD:1624291
G Ctdspl CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like GBrowse link 8 123,960,578 123,993,452 RGD:1624291
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link 6 93,402,304 93,411,668 RGD:1600115
RGD:1624291
G E2f7 E2F transcription factor 7 GBrowse link 7 49,689,755 49,751,823 RGD:1600115
RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit GBrowse link 4 75,709,959 75,773,279 RGD:1600115
RGD:1624291
G Fbxo7 F-box protein 7 GBrowse link 7 19,947,498 19,975,730 RGD:1624291
G Fhl1 four and a half LIM domains 1 GBrowse link X 141,315,765 141,329,278 RGD:1600115
RGD:1624291
G Gsg2 germ cell associated 2 (haspin) RGD:1600115
RGD:1624291
G Jade1 jade family PHD finger 1 GBrowse link 2 128,499,983 128,553,050 RGD:1600115
RGD:1624291
G Kank2 KN motif and ankyrin repeat domains 2 GBrowse link 8 20,865,615 20,892,573 RGD:1600115
RGD:1624291
G Myo16 myosin XVI GBrowse link 16 83,812,189 84,174,521 RGD:8554212
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link 14 6,349,519 6,392,988 RGD:1600115
RGD:1624291
G Prmt2 protein arginine methyltransferase 2 GBrowse link 20 12,800,400 12,817,018 RGD:1624291
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:1624291
G Rb1 retinoblastoma 1 GBrowse link 15 53,828,881 53,962,099 RGD:1600115
RGD:1624291
G Slfn3 schlafen 3 GBrowse link 10 71,277,765 71,301,183 RGD:1624291
G Zc3h12d zinc finger CCCH type containing 12D GBrowse link 1 2,507,365 2,541,861 RGD:1600115
RGD:1624291
G Zfp655 zinc finger protein 655 GBrowse link 12 9,670,178 9,687,864 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Nacc2 NACC family member 2, BEN and BTB (POZ) domain containing GBrowse link 3 4,237,814 4,301,608 RGD:1600115
RGD:1624291
G Slfn1 schlafen 1 GBrowse link 10 71,264,746 71,265,762 RGD:1600115
G Slfn3 schlafen 3 GBrowse link 10 71,277,765 71,301,183 RGD:1624291
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 GBrowse link 6 41,882,432 41,930,755 RGD:1600115
RGD:1624291
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link 6 137,640,482 137,657,552 RGD:1600115
RGD:1624291
G Egfr epidermal growth factor receptor GBrowse link 14 97,617,358 97,788,211 RGD:1600115
RGD:1624291
G Fgf10 fibroblast growth factor 10 GBrowse link 2 50,866,799 50,940,319 RGD:1600115
RGD:1624291
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase GBrowse link 20 7,817,403 7,821,800 RGD:1600115
RGD:1624291
G Pkd1 polycystic kidney disease 1 GBrowse link 10 13,801,445 13,848,212 RGD:1600115
RGD:1624291
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link 14 6,349,519 6,392,988 RGD:1600115
RGD:1624291
G Rgcc regulator of cell cycle GBrowse link 15 60,451,831 60,452,229 RGD:1600115
RGD:1624291
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 GBrowse link 20 3,714,428 3,716,327 RGD:1600115
RGD:1624291
G Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B GBrowse link 5 63,044,718 63,058,038 RGD:633716
G Anxa1 annexin A1 GBrowse link 1 223,478,436 223,494,455 RGD:1600115
RGD:1624291
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link 15 26,904,124 26,906,224 RGD:2315680
G Crebbp CREB binding protein GBrowse link 10 11,598,680 11,724,122 RGD:2316124
G Cul4a cullin 4A GBrowse link 16 81,242,293 81,279,498 RGD:1600115
RGD:1624291
G Cul4b cullin 4B GBrowse link X 6,800,506 6,838,023 RGD:1600115
RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link 8 61,462,207 61,468,237 RGD:2306669
G Ddx3x DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked GBrowse link X 21,495,072 21,508,690 RGD:1624291
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 GBrowse link 4 162,896,283 162,898,091 RGD:7242757
G Larp7 La ribonucleoprotein domain family, member 7 RGD:1624291
G Mepce methylphosphate capping enzyme GBrowse link 12 19,848,913 19,853,632 RGD:1624291
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 122,797,718 123,523,675 RGD:1600115
RGD:1624291
G Plrg1 pleiotropic regulator 1 GBrowse link 2 174,780,415 174,796,746 RGD:1624291
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C GBrowse link 3 62,519,426 62,622,517 RGD:1600115
RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA activated, catalytic polypeptide GBrowse link 11 86,951,420 87,169,229 RGD:1624291
traversing start control point of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 56,996,694 57,020,926 RGD:1600115
RGD:1624291
G Mtbp Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein GBrowse link 7 92,068,823 92,146,616 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 171926
    regulation of biological process 66499
      regulation of cellular process 55851
        regulation of cell cycle 1671
          regulation of mitotic cell cycle 689
            regulation of mitotic cell cycle phase transition 402
              regulation of G1/S transition of mitotic cell cycle 163
                negative regulation of G1/S transition of mitotic cell cycle + 89
                positive regulation of G1/S transition of mitotic cell cycle + 45
                regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 19
Path 2
Term Annotations click to browse term
  biological_process 171926
    cellular process 105984
      single-organism cellular process 69332
        cell cycle 3037
          cell cycle process 2342
            cell cycle phase transition 618
              mitotic cell cycle phase transition 599
                G1/S transition of mitotic cell cycle 281
                  regulation of G1/S transition of mitotic cell cycle 163
                    negative regulation of G1/S transition of mitotic cell cycle + 89
                    positive regulation of G1/S transition of mitotic cell cycle + 45
                    regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 19
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