ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G1/S transition of mitotic cell cycle
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Accession:GO:2000045 term browser browse the term
Definition:Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
Comment:Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.


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regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bid BH3 interacting domain death agonist GBrowse link 4 157,296,383 157,318,481 RGD:1600115
G E2f1 E2F transcription factor 1 GBrowse link 3 145,032,489 145,043,729 RGD:1600115
RGD:1624291
G Ecd ecdysoneless homolog (Drosophila) RGD:1600115
RGD:1624291
G Id2 inhibitor of DNA binding 2 GBrowse link 6 42,781,476 42,783,307 RGD:1600115
RGD:1624291
G Ino80 INO80 complex subunit GBrowse link 3 105,898,279 105,979,698 RGD:1600115
RGD:1624291
G Pdpn podoplanin GBrowse link 5 162,142,251 162,175,921 RGD:1600115
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link 9 83,412,797 83,429,039 RGD:1600115
RGD:1624291
G Plk5 polo-like kinase 5 GBrowse link 7 10,858,118 10,866,430 RGD:1600115
RGD:1624291
G Ptpla protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a GBrowse link 17 88,239,568 88,253,571 RGD:1600115
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link 4 160,843,699 160,868,856 RGD:1600115
RGD:1624291
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 GBrowse link 11 81,225,720 81,259,934 RGD:1600115
RGD:1624291
G Tcf3 transcription factor 3 GBrowse link 7 10,791,311 10,813,613 RGD:1600115
RGD:1624291
G Tjp3 tight junction protein 3 GBrowse link 7 9,917,359 9,930,081 RGD:1600115
RGD:1624291
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Casp2 caspase 2 GBrowse link 4 70,029,728 70,047,164 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link 20 7,376,325 7,386,778 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link 7 32,504,279 32,517,581 RGD:1600115
RGD:1624291
G LOC100911519 p53-induced protein with a death domain-like RGD:1624291
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 56,996,694 57,020,926 RGD:1600115
RGD:1624291
G Muc1 mucin 1, cell surface associated GBrowse link 2 181,399,482 181,403,640 RGD:1600115
RGD:1624291
G Pcbp4 poly(rC) binding protein 4 GBrowse link 8 111,597,539 111,607,775 RGD:1624291
G Pml promyelocytic leukemia GBrowse link 8 62,020,438 62,051,927 RGD:1600115
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link 6 135,204,405 135,299,068 RGD:1600115
RGD:1624291
G Rbm38 RNA binding motif protein 38 GBrowse link 3 163,885,488 163,898,314 RGD:1600115
RGD:1624291
G Sox4 SRY (sex determining region Y)-box 4 GBrowse link 17 42,172,863 42,177,590 RGD:1624291
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 GBrowse link 1 205,357,235 205,366,757 RGD:1600115
RGD:1624291
G Dgkz diacylglycerol kinase zeta GBrowse link 3 76,312,721 76,342,603 RGD:1600115
RGD:1624291
G Fbxo31 F-box protein 31 GBrowse link 19 51,836,918 51,837,223 RGD:1600115
RGD:1624291
G LOC498414 LRRGT00197 RGD:1600115
G Rfwd3 ring finger and WD repeat domain 3 GBrowse link 19 41,190,144 41,222,888 RGD:1624291
G Rpa2 replication protein A2 GBrowse link 5 152,369,550 152,380,370 RGD:1600115
RGD:1624291
G Rps27l ribosomal protein S27-like RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 56,399,721 56,411,150 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 GBrowse link 11 76,900,622 77,200,251 RGD:1600115
G Tp73 tumor protein p73 GBrowse link 5 170,848,979 171,078,739 RGD:1600115
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link 13 12,730,736 12,905,108 RGD:1600115
G Brd7 bromodomain containing 7 GBrowse link 19 20,019,637 20,048,264 RGD:1600115
RGD:1624291
G Cdc73 cell division cycle 73 GBrowse link 13 57,441,674 57,534,385 RGD:1600115
RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link 5 108,939,669 108,945,293 RGD:1600115
RGD:1624291
G Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 RGD:1624291
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link 6 93,402,304 93,411,668 RGD:1600115
RGD:1624291
G E2f7 E2F transcription factor 7 GBrowse link 7 49,689,755 49,751,823 RGD:1600115
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit GBrowse link 4 75,709,959 75,773,279 RGD:1600115
G Fbxo7 F-box protein 7 GBrowse link 7 19,947,498 19,975,730 RGD:1600115
G Fhl1 four and a half LIM domains 1 GBrowse link X 141,315,765 141,329,278 RGD:1600115
RGD:1624291
G Gsg2 germ cell associated 2 (haspin) RGD:1600115
G Jade1 jade family PHD finger 1 GBrowse link 2 128,499,983 128,553,050 RGD:1600115
RGD:1624291
G Kank2 KN motif and ankyrin repeat domains 2 GBrowse link 8 20,865,615 20,892,573 RGD:1600115
RGD:1624291
G Mir26a microRNA 26a RGD:1624291
G Myo16 myosin XVI GBrowse link 16 83,812,189 84,174,521 RGD:8554212
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link 14 6,349,519 6,392,988 RGD:1600115
RGD:1624291
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:1600115
RGD:1624291
G Rb1 retinoblastoma 1 GBrowse link 15 53,828,881 53,962,099 RGD:1600115
G Zc3h12d zinc finger CCCH type containing 12D GBrowse link 1 2,507,365 2,541,861 RGD:1600115
RGD:1624291
G Zfp655 zinc finger protein 655 GBrowse link 12 9,670,178 9,687,864 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Nacc2 NACC family member 2, BEN and BTB (POZ) domain containing GBrowse link 3 4,237,814 4,301,608 RGD:1600115
RGD:1624291
G Slfn1 schlafen 1 GBrowse link 10 71,264,746 71,265,762 RGD:1600115
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 GBrowse link 20 3,714,428 3,716,327 RGD:1600115
RGD:1624291
G Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B GBrowse link 5 63,044,718 63,058,038 RGD:633716
G Anxa1 annexin A1 GBrowse link 1 223,478,436 223,494,455 RGD:1600115
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link 15 26,904,124 26,906,224 RGD:2315680
G Crebbp CREB binding protein GBrowse link 10 11,598,680 11,724,122 RGD:2316124
G Cul4a cullin 4A GBrowse link 16 81,242,293 81,279,498 RGD:1600115
G Cul4b cullin 4B GBrowse link X 6,800,506 6,838,023 RGD:1600115
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link 8 61,462,207 61,468,237 RGD:2306669
G Ddx3y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked GBrowse link 13 103,083,158 103,086,327 RGD:1624291
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 GBrowse link 4 162,896,283 162,898,091 RGD:7242757
G Larp7 La ribonucleoprotein domain family, member 7 RGD:1624291
G Lsm10 LSM10, U7 small nuclear RNA associated GBrowse link 5 145,450,575 145,452,403 RGD:1624291
G Lsm11 LSM11, U7 small nuclear RNA associated GBrowse link 10 31,070,515 31,084,314 RGD:1624291
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 122,797,718 123,523,675 RGD:1600115
G Plrg1 pleiotropic regulator 1 GBrowse link 2 174,780,415 174,796,746 RGD:1600115
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C GBrowse link 3 62,519,426 62,622,517 RGD:1600115
RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA activated, catalytic polypeptide GBrowse link 11 86,951,420 87,169,229 RGD:1600115
RGD:1624291
traversing start control point of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 56,996,694 57,020,926 RGD:1600115
G Mtbp Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein GBrowse link 7 92,068,823 92,146,616 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 140990
    regulation of biological process 55188
      regulation of cellular process 46553
        regulation of cell cycle 1480
          regulation of mitotic cell cycle 613
            regulation of mitotic cell cycle phase transition 348
              regulation of G1/S transition of mitotic cell cycle 119
                negative regulation of G1/S transition of mitotic cell cycle + 72
                positive regulation of G1/S transition of mitotic cell cycle + 23
Path 2
Term Annotations click to browse term
  biological_process 140990
    cellular process 88517
      single-organism cellular process 57391
        cell cycle 2629
          cell cycle process 2050
            cell cycle phase transition 560
              mitotic cell cycle phase transition 537
                G1/S transition of mitotic cell cycle 242
                  regulation of G1/S transition of mitotic cell cycle 119
                    negative regulation of G1/S transition of mitotic cell cycle + 72
                    positive regulation of G1/S transition of mitotic cell cycle + 23
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