ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G1/S transition of mitotic cell cycle
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Accession:GO:2000045 term browser browse the term
Definition:Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
Comment:Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.


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regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bid BH3 interacting domain death agonist GBrowse link ISO 4 157,296,383 157,318,481 RGD:1624291 RGD
G Bid BH3 interacting domain death agonist GBrowse link IEA 4 157,296,383 157,318,481 RGD:1600115 Ensembl
G Ccnd1 cyclin D1 GBrowse link ISO 1 205,357,235 205,366,757 RGD:1624291 RGD
G E2f1 E2F transcription factor 1 GBrowse link ISO 3 145,032,489 145,043,729 RGD:1624291 RGD
G E2f1 E2F transcription factor 1 GBrowse link IEA 3 145,032,489 145,043,729 RGD:1600115 Ensembl
G Ecd ecdysoneless homolog (Drosophila) ISO RGD:1624291 RGD
G Ecd ecdysoneless homolog (Drosophila) IEA RGD:1600115 Ensembl
G Id2 inhibitor of DNA binding 2 GBrowse link ISO 6 42,781,476 42,783,307 RGD:1624291 RGD
G Id2 inhibitor of DNA binding 2 GBrowse link IEA 6 42,781,476 42,783,307 RGD:1600115 Ensembl
G Ino80 INO80 complex subunit GBrowse link ISO 3 105,898,279 105,979,698 RGD:1624291 RGD
G Ino80 INO80 complex subunit GBrowse link IEA 3 105,898,279 105,979,698 RGD:1600115 Ensembl
G Pdpn podoplanin GBrowse link ISO 5 162,142,251 162,175,921 RGD:1624291 RGD
G Pdpn podoplanin GBrowse link IEA 5 162,142,251 162,175,921 RGD:1600115 Ensembl
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link ISO 9 83,412,797 83,429,039 RGD:1624291 RGD
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link IEA 9 83,412,797 83,429,039 RGD:1600115 Ensembl
G Plk5 polo-like kinase 5 GBrowse link IEA 7 10,858,118 10,866,430 RGD:1600115 Ensembl
G Plk5 polo-like kinase 5 GBrowse link ISO 7 10,858,118 10,866,430 RGD:1624291 RGD
G Plk5 polo-like kinase 5 GBrowse link ISO 7 10,858,118 10,866,430 RGD:1624291 RGD
G Plk5 polo-like kinase 5 GBrowse link ISO 7 10,858,118 10,866,430 RGD:1624291 RGD
G Ptpla protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a GBrowse link ISO 17 88,239,568 88,253,571 RGD:1624291 RGD
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link ISO 4 160,843,699 160,868,856 RGD:1624291 RGD
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link IEA 4 160,843,699 160,868,856 RGD:1600115 Ensembl
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 GBrowse link ISO 11 81,225,720 81,259,934 RGD:1624291 RGD
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 GBrowse link IEA 11 81,225,720 81,259,934 RGD:1600115 Ensembl
G Tcf3 transcription factor 3 GBrowse link ISO 7 10,791,311 10,813,613 RGD:1624291 RGD
G Tcf3 transcription factor 3 GBrowse link ISS 7 10,791,311 10,813,613 RGD:1600115 UniProt
G Tcf3 transcription factor 3 GBrowse link IEA 7 10,791,311 10,813,613 RGD:1600115 Ensembl
G Tjp3 tight junction protein 3 GBrowse link ISO 7 9,917,359 9,930,081 RGD:1624291 RGD
G Tjp3 tight junction protein 3 GBrowse link IEA 7 9,917,359 9,930,081 RGD:1600115 Ensembl
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Casp2 caspase 2 GBrowse link ISO 4 70,029,728 70,047,164 RGD:1624291 RGD
G Casp2 caspase 2 GBrowse link IEA 4 70,029,728 70,047,164 RGD:1600115 Ensembl
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link ISO 20 7,376,325 7,386,778 RGD:1624291 RGD
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link IEA 20 7,376,325 7,386,778 RGD:1600115 Ensembl
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link IEA 7 32,504,279 32,517,581 RGD:1600115 Ensembl
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link ISO 7 32,504,279 32,517,581 RGD:1624291 RGD
G Mdm2 MDM2 oncogene, E3 ubiquitin protein ligase GBrowse link IEA 7 56,996,694 57,020,926 RGD:1600115 Ensembl
G Mdm2 MDM2 oncogene, E3 ubiquitin protein ligase GBrowse link ISO 7 56,996,694 57,020,926 RGD:1624291 RGD
G Muc1 mucin 1, cell surface associated GBrowse link ISO 2 181,399,482 181,403,640 RGD:1624291 RGD
G Pcbp4 poly(rC) binding protein 4 GBrowse link ISO 8 111,597,539 111,607,775 RGD:1624291 RGD
G Pidd p53-induced death domain protein GBrowse link ISO 1 201,626,042 201,631,182 RGD:1624291 RGD
G Pml promyelocytic leukemia GBrowse link ISO 8 62,020,438 62,051,927 RGD:1624291 RGD
G Pml promyelocytic leukemia GBrowse link IEA 8 62,020,438 62,051,927 RGD:1600115 Ensembl
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link ISO 6 135,204,405 135,299,068 RGD:1624291 RGD
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link IEA 6 135,204,405 135,299,068 RGD:1600115 Ensembl
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link ISO 13 48,070,488 48,090,682 RGD:1624291 RGD
G Rbm38 RNA binding motif protein 38 GBrowse link IEA 3 163,885,488 163,898,314 RGD:1600115 Ensembl
G Rbm38 RNA binding motif protein 38 GBrowse link ISO 3 163,885,488 163,898,314 RGD:1624291 RGD
G Sox4 SRY (sex determining region Y)-box 4 GBrowse link ISO 17 42,172,863 42,177,590 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccnd1 cyclin D1 GBrowse link ISO 1 205,357,235 205,366,757 RGD:1624291 RGD
G Ccnd1 cyclin D1 GBrowse link ISS 1 205,357,235 205,366,757 RGD:1600115 UniProt
G Dgkz diacylglycerol kinase zeta GBrowse link ISO 3 76,312,721 76,342,603 RGD:1624291 RGD
G Dgkz diacylglycerol kinase zeta GBrowse link IEA 3 76,312,721 76,342,603 RGD:1600115 Ensembl
G Fbxo31 F-box protein 31 GBrowse link ISS 19 51,836,918 51,837,223 RGD:1600115 UniProt
G Fbxo31 F-box protein 31 GBrowse link ISO 19 51,836,918 51,837,223 RGD:1624291 RGD
G Gigyf2 GRB10 interacting GYF protein 2 GBrowse link ISO 9 86,143,324 86,273,766 RGD:1624291 RGD
G LOC100910954 cellular tumor antigen p53-like IEA RGD:1600115 Ensembl
G LOC498414 LRRGT00197 IBA RGD:1600115 RefGenome
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link ISO 13 48,070,488 48,090,682 RGD:1624291 RGD
G Rfwd3 ring finger and WD repeat domain 3 GBrowse link ISO 19 41,190,144 41,222,888 RGD:1624291 RGD
G Rps27l ribosomal protein S27-like IEA RGD:1600115 Ensembl
G Rps27l ribosomal protein S27-like ISO RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Tp53 tumor protein p53 GBrowse link IBA 10 56,399,721 56,411,150 RGD:1600115 RefGenome
G Tp73 tumor protein p73 GBrowse link IBA 5 170,848,979 171,078,739 RGD:1600115 RefGenome
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Pten phosphatase and tensin homolog GBrowse link ISO 1 236,771,027 236,837,261 RGD:1624291 RGD
G Pten phosphatase and tensin homolog GBrowse link IEA 1 236,771,027 236,837,261 RGD:1600115 Ensembl
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link ISO 13 12,730,736 12,905,108 RGD:1624291 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link ISO 13 12,730,736 12,905,108 RGD:1624291 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link IEA 13 12,730,736 12,905,108 RGD:1600115 Ensembl
G Brd7 bromodomain containing 7 GBrowse link ISO 19 20,019,637 20,048,264 RGD:1624291 RGD
G Brd7 bromodomain containing 7 GBrowse link IEA 19 20,019,637 20,048,264 RGD:1600115 Ensembl
G Cdc73 cell division cycle 73 GBrowse link IEA 13 57,441,674 57,534,385 RGD:1600115 Ensembl
G Cdc73 cell division cycle 73 GBrowse link ISO 13 57,441,674 57,534,385 RGD:1624291 RGD
G Cdc73 cell division cycle 73 GBrowse link ISS 13 57,441,674 57,534,385 RGD:1600115 UniProt
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link ISO 5 108,939,669 108,945,293 RGD:1624291 RGD
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link IEA 5 108,939,669 108,945,293 RGD:1600115 Ensembl
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link ISO 6 93,402,304 93,411,668 RGD:1624291 RGD
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link IEA 6 93,402,304 93,411,668 RGD:1600115 Ensembl
G E2f7 E2F transcription factor 7 GBrowse link ISS 7 49,689,755 49,751,823 RGD:1600115 UniProt
G E2f7 E2F transcription factor 7 GBrowse link ISO 7 49,689,755 49,751,823 RGD:1624291 RGD
G Ezh2 enhancer of zeste homolog 2 (Drosophila) GBrowse link IEA 4 75,709,959 75,773,279 RGD:1600115 Ensembl
G Ezh2 enhancer of zeste homolog 2 (Drosophila) GBrowse link ISO 4 75,709,959 75,773,279 RGD:1624291 RGD
G Fbxo7 F-box protein 7 GBrowse link ISO 7 19,947,498 19,975,730 RGD:1624291 RGD
G Fhl1 four and a half LIM domains 1 GBrowse link ISO X 141,315,765 141,329,278 RGD:1624291 RGD
G Fhl1 four and a half LIM domains 1 GBrowse link IEA X 141,315,765 141,329,278 RGD:1600115 Ensembl
G Gsg2 germ cell associated 2 (haspin) ISO RGD:1624291 RGD
G Gsg2 germ cell associated 2 (haspin) IEA RGD:1600115 Ensembl
G Jade1 jade family PHD finger 1 GBrowse link ISO 2 128,499,983 128,553,050 RGD:1624291 RGD
G Jade1 jade family PHD finger 1 GBrowse link IEA 2 128,499,983 128,553,050 RGD:1600115 Ensembl
G Kank2 KN motif and ankyrin repeat domains 2 GBrowse link ISO 8 20,865,615 20,892,573 RGD:1624291 RGD
G Kank2 KN motif and ankyrin repeat domains 2 GBrowse link IEA 8 20,865,615 20,892,573 RGD:1600115 Ensembl
G Myo16 myosin XVI GBrowse link IDA 16 83,812,189 84,174,521 BHF-UCL
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link ISO 14 6,349,519 6,392,988 RGD:1624291 RGD
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link IEA 14 6,349,519 6,392,988 RGD:1600115 Ensembl
G Prmt2 protein arginine methyltransferase 2 GBrowse link ISO 20 12,800,400 12,817,018 RGD:1624291 RGD
G Pten phosphatase and tensin homolog GBrowse link ISO 1 236,771,027 236,837,261 RGD:1624291 RGD
G Rb1 retinoblastoma 1 GBrowse link ISO 15 53,828,881 53,962,099 RGD:1624291 RGD
G Rb1 retinoblastoma 1 GBrowse link IEA 15 53,828,881 53,962,099 RGD:1600115 Ensembl
G Slfn3 schlafen 3 GBrowse link ISO 10 71,277,765 71,301,183 RGD:1624291 RGD
G Slfn3 schlafen 3 GBrowse link ISO 10 71,277,765 71,301,183 RGD:1624291 RGD
G Zc3h12d zinc finger CCCH type containing 12D GBrowse link ISO 1 2,507,365 2,541,861 RGD:1624291 RGD
G Zc3h12d zinc finger CCCH type containing 12D GBrowse link IEA 1 2,507,365 2,541,861 RGD:1600115 Ensembl
G Zfp655 zinc finger protein 655 GBrowse link ISS 12 9,670,178 9,687,864 RGD:1600115 UniProt
G Zfp655 zinc finger protein 655 GBrowse link ISO 12 9,670,178 9,687,864 RGD:1624291 RGD
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Nacc2 NACC family member 2, BEN and BTB (POZ) domain containing GBrowse link IEA 3 4,237,814 4,301,608 RGD:1600115 Ensembl
G Nacc2 NACC family member 2, BEN and BTB (POZ) domain containing GBrowse link ISO 3 4,237,814 4,301,608 RGD:1624291 RGD
G Slfn1 schlafen 1 GBrowse link IEA 10 71,264,746 71,265,762 RGD:1600115 Ensembl
G Slfn3 schlafen 3 GBrowse link ISO 10 71,277,765 71,301,183 RGD:1624291 RGD
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adam17 ADAM metallopeptidase domain 17 GBrowse link ISO 6 41,882,432 41,930,755 RGD:1624291 RGD
G Adam17 ADAM metallopeptidase domain 17 GBrowse link IEA 6 41,882,432 41,930,755 RGD:1600115 Ensembl
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link ISO 6 137,640,482 137,657,552 RGD:1624291 RGD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link IEA 6 137,640,482 137,657,552 RGD:1600115 Ensembl
G Egfr epidermal growth factor receptor GBrowse link ISO 14 97,617,358 97,788,211 RGD:1624291 RGD
G Egfr epidermal growth factor receptor GBrowse link IEA 14 97,617,358 97,788,211 RGD:1600115 Ensembl
G Fgf10 fibroblast growth factor 10 GBrowse link ISO 2 50,866,799 50,940,319 RGD:1624291 RGD
G Fgf10 fibroblast growth factor 10 GBrowse link IEA 2 50,866,799 50,940,319 RGD:1600115 Ensembl
G Pim1 pim-1 oncogene GBrowse link ISO 20 7,817,403 7,821,800 RGD:1624291 RGD
G Pim1 pim-1 oncogene GBrowse link IEA 20 7,817,403 7,821,800 RGD:1600115 Ensembl
G Pkd1 polycystic kidney disease 1 GBrowse link ISO 10 13,801,445 13,848,212 RGD:1624291 RGD
G Pkd1 polycystic kidney disease 1 GBrowse link IEA 10 13,801,445 13,848,212 RGD:1600115 Ensembl
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link IEA 14 6,349,519 6,392,988 RGD:1600115 Ensembl
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link ISO 14 6,349,519 6,392,988 RGD:1624291 RGD
G Rgcc regulator of cell cycle GBrowse link IEA 15 60,451,831 60,452,229 RGD:1600115 Ensembl
G Rgcc regulator of cell cycle GBrowse link ISO 15 60,451,831 60,452,229 RGD:1624291 RGD
G Rgcc regulator of cell cycle GBrowse link ISO 15 60,451,831 60,452,229 RGD:1624291 RGD
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Aif1 allograft inflammatory factor 1 GBrowse link ISO 20 3,714,428 3,716,327 RGD:1624291 RGD
G Aif1 allograft inflammatory factor 1 GBrowse link ISO 20 3,714,428 3,716,327 RGD:1624291 RGD
G Aif1 allograft inflammatory factor 1 GBrowse link IEA 20 3,714,428 3,716,327 RGD:1600115 Ensembl
G Aif1 allograft inflammatory factor 1 GBrowse link ISS 20 3,714,428 3,716,327 RGD:1600115 UniProt
G Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B GBrowse link IMP 5 63,044,718 63,058,038 RGD:633716 RGD
G Anxa1 annexin A1 GBrowse link ISO 1 223,478,436 223,494,455 RGD:1624291 RGD
G Anxa1 annexin A1 GBrowse link IEA 1 223,478,436 223,494,455 RGD:1600115 Ensembl
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link IMP 15 26,904,124 26,906,224 RGD:2315680 RGD
G Crebbp CREB binding protein GBrowse link IMP 10 11,598,680 11,724,122 RGD:2316124 RGD
G Cul4a cullin 4A GBrowse link ISO 16 81,242,293 81,279,498 RGD:1624291 RGD
G Cul4a cullin 4A GBrowse link IEA 16 81,242,293 81,279,498 RGD:1600115 Ensembl
G Cul4b cullin 4B GBrowse link ISO X 6,800,506 6,838,023 RGD:1624291 RGD
G Cul4b cullin 4B GBrowse link IEA X 6,800,506 6,838,023 RGD:1600115 Ensembl
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link IDA 8 61,462,207 61,468,237 RGD:2306669 RGD
G Ddx3x DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked GBrowse link ISO X 21,495,072 21,508,690 RGD:1624291 RGD
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 GBrowse link IDA 4 162,896,283 162,898,091 RGD:7242757 RGD
G Larp7 La ribonucleoprotein domain family, member 7 ISO RGD:1624291 RGD
G Mepce methylphosphate capping enzyme GBrowse link ISO 12 19,848,913 19,853,632 RGD:1624291 RGD
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link ISS 3 122,797,718 123,523,675 RGD:1600115 BHF-UCL
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link ISO 3 122,797,718 123,523,675 RGD:1624291 RGD
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link IEA 3 122,797,718 123,523,675 RGD:1600115 Ensembl
G Plrg1 pleiotropic regulator 1 GBrowse link ISO 2 174,780,415 174,796,746 RGD:1624291 RGD
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C GBrowse link ISO 3 62,519,426 62,622,517 RGD:1624291 RGD
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C GBrowse link IEA 3 62,519,426 62,622,517 RGD:1600115 Ensembl
traversing start control point of mitotic cell cycle term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Mdm2 MDM2 oncogene, E3 ubiquitin protein ligase GBrowse link ISO 7 56,996,694 57,020,926 RGD:1624291 RGD
G Mdm2 MDM2 oncogene, E3 ubiquitin protein ligase GBrowse link IEA 7 56,996,694 57,020,926 RGD:1600115 Ensembl
G Mtbp Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein GBrowse link ISO 7 92,068,823 92,146,616 RGD:1624291 RGD
G Mtbp Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein GBrowse link IEA 7 92,068,823 92,146,616 RGD:1600115 Ensembl

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 157925
    cellular process 98417
      regulation of cellular process 51127
        regulation of cell cycle 1590
          regulation of mitotic cell cycle 656
            regulation of mitotic cell cycle phase transition 381
              regulation of G1/S transition of mitotic cell cycle 155
                negative regulation of G1/S transition of mitotic cell cycle + 81
                positive regulation of G1/S transition of mitotic cell cycle + 45
                regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 19
Path 2
Term Annotations click to browse term
  biological_process 157925
    biological regulation 66965
      regulation of biological process 61052
        regulation of cellular process 51127
          regulation of cell cycle 1590
            regulation of cell cycle process 911
              regulation of cell cycle phase transition 389
                regulation of cell cycle G1/S phase transition 155
                  regulation of G1/S transition of mitotic cell cycle 155
                    negative regulation of G1/S transition of mitotic cell cycle + 81
                    positive regulation of G1/S transition of mitotic cell cycle + 45
                    regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 19
paths to the root