ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G1/S transition of mitotic cell cycle
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Accession:GO:2000045 term browser browse the term
Definition:Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
Comment:Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.


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regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:1600115
RGD:1624291
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:1600115
RGD:1624291
G Ecd ecdysoneless cell cycle regulator JBrowse link 15 4,399,829 4,431,268 RGD:1600115
RGD:1624291
G Hacd1 3-hydroxyacyl-CoA dehydratase 1 JBrowse link 17 81,173,238 81,196,012 RGD:1624291
G Id2 inhibitor of DNA binding 2, HLH protein JBrowse link 6 44,360,077 44,361,908 RGD:1600115
RGD:1624291
G Ino80 INO80 complex subunit JBrowse link 3 111,186,371 111,266,542 RGD:1600115
RGD:1624291
G Kif14 kinesin family member 14 JBrowse link 13 53,350,073 53,421,992 RGD:1600115
RGD:1624291
G Pdpn podoplanin JBrowse link 5 161,947,137 161,981,441 RGD:1600115
RGD:1624291
G Pid1 phosphotyrosine interaction domain containing 1 JBrowse link 9 91,667,748 91,683,468 RGD:1600115
RGD:1624291
G Plk5 polo-like kinase 5 JBrowse link 7 12,212,910 12,234,253 RGD:1600115
RGD:1624291
G Psme1 proteasome activator subunit 1 JBrowse link 15 34,256,071 34,258,947 RGD:1600115
G Psme2 proteasome activator subunit 2 JBrowse link 15 34,265,552 34,269,851 RGD:1600115
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 JBrowse link 4 157,239,141 157,263,890 RGD:1600115
RGD:1624291
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 JBrowse link 11 82,627,973 82,664,702 RGD:1600115
RGD:1624291
G Tcf3 transcription factor 3 JBrowse link 7 12,146,642 12,168,400 RGD:1600115
RGD:1624291
G Tjp3 tight junction protein 3 JBrowse link 7 11,295,892 11,314,535 RGD:1624291
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1600115
RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1600115
RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1600115
RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1600115
RGD:1624291
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1600115
RGD:1624291
G Sox4 SRY box 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1600115
RGD:1624291
G Dgkz diacylglycerol kinase zeta JBrowse link 3 80,844,002 80,886,487 RGD:1600115
RGD:1624291
G Fbxo31 F-box protein 31 JBrowse link 19 53,487,610 53,625,673 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 JBrowse link 9 94,425,191 94,550,431 RGD:1600115
RGD:1624291
G LOC100910954 cellular tumor antigen p53-like JBrowse link 2 49,338,328 49,383,164 RGD:1600115
G LOC498414 LRRGT00197 JBrowse link 14 90,822,951 90,864,917 RGD:1600115
G LOC500594 LRRGT00162 JBrowse link 5 169,632,527 169,637,356 RGD:1600115
G Rfwd3 ring finger and WD repeat domain 3 JBrowse link 19 42,960,597 42,971,894 RGD:1624291
G Rpa2 replication protein A2 JBrowse link 5 150,957,041 150,967,597 RGD:1600115
RGD:1624291
G Rps27l ribosomal protein S27-like JBrowse link 8 72,741,155 72,746,090 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 JBrowse link 11 78,234,853 78,456,559 RGD:1600115
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1600115
mitotic G1/S transition checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Plk3 polo-like kinase 3 JBrowse link 5 135,997,725 136,002,900 RGD:1600115
RGD:1624291
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:1600115
RGD:1624291
G Brd7 bromodomain containing 7 JBrowse link 19 19,672,780 19,701,484 RGD:1600115
RGD:1624291
G Btn2a2 butyrophilin, subfamily 2, member A2 JBrowse link 17 43,867,243 43,878,734 RGD:1600115
RGD:1624291
G Cdc73 cell division cycle 73 JBrowse link 13 60,403,771 60,496,511 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:1600115
RGD:1624291
G Ctdsp1 CTD small phosphatase 1 JBrowse link 9 81,672,613 81,677,979 RGD:1600115
RGD:1624291
G Ctdsp2 CTD small phosphatase 2 JBrowse link 7 70,283,683 70,291,795 RGD:1600115
RGD:1624291
G Ctdspl CTD small phosphatase like JBrowse link 8 127,065,292 127,726,248 RGD:1600115
RGD:1624291
G Dact1 dishevelled-binding antagonist of beta-catenin 1 JBrowse link 6 93,740,440 93,751,003 RGD:1600115
RGD:1624291
G E2f7 E2F transcription factor 7 JBrowse link 7 53,275,659 53,318,261 RGD:1600115
RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:1600115
RGD:1624291
G Fbxo7 F-box protein 7 JBrowse link 7 23,815,246 23,843,505 RGD:1600115
RGD:1624291
G Fhl1 four and a half LIM domains 1 JBrowse link X 159,112,516 159,172,528 RGD:1600115
RGD:1624291
G Gsg2 germ cell associated 2 (haspin) JBrowse link 10 59,695,403 59,698,398 RGD:1624291
G Jade1 jade family PHD finger 1 JBrowse link 2 128,461,147 128,514,298 RGD:1600115
RGD:1624291
G Kank2 KN motif and ankyrin repeat domains 2 JBrowse link 8 22,792,000 22,821,459 RGD:1600115
RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1600115
RGD:1624291
G Prmt2 protein arginine methyltransferase 2 JBrowse link 20 13,154,513 13,212,613 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1600115
RGD:1624291
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:1600115
RGD:1624291
G Slfn13 schlafen family member 13 JBrowse link 10 70,326,157 70,343,024 RGD:1600115
RGD:1624291
G Slfn2 schlafen 2 JBrowse link 10 70,370,381 70,376,718 RGD:1624291
G Zc3h12d zinc finger CCCH type containing 12D JBrowse link 1 1,937,620 1,972,919 RGD:1600115
RGD:1624291
G Zfp655 zinc finger protein 655 JBrowse link 12 11,122,779 11,146,182 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nacc2 NACC family member 2 JBrowse link 3 3,508,084 3,574,787 RGD:1600115
RGD:1624291
G Slfn2 schlafen 2 JBrowse link 10 70,370,381 70,376,718 RGD:1624291
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1600115
RGD:1624291
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1600115
RGD:1624291
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1600115
RGD:1624291
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1600115
RGD:1624291
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:1600115
RGD:1624291
G Pkd1 polycystic kidney disease 1 JBrowse link 10 13,914,057 13,962,008 RGD:1600115
RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1600115
RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1600115
RGD:1624291
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:1600115
RGD:1624291
G Ankrd17 ankyrin repeat domain 17 JBrowse link 14 19,291,025 19,431,521 RGD:1600115
RGD:1624291
G Anp32b acidic nuclear phosphoprotein 32 family member B JBrowse link 5 62,070,709 62,094,633 RGD:633716
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:1600115
RGD:1624291
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:2315680
G Cdc45 cell division cycle 45 JBrowse link 11 86,328,785 86,354,099 RGD:1600115
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:2316124
G Cul4a cullin 4A JBrowse link 16 81,718,784 81,756,653 RGD:1600115
RGD:1624291
G Cul4b cullin 4B JBrowse link X 124,831,391 124,870,329 RGD:1600115
RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:2306669
G Ddx3x DEAD-box helicase 3, X-linked JBrowse link X 10,400,363 10,414,010 RGD:1624291
G Kcna5 potassium voltage-gated channel subfamily A member 5 JBrowse link 4 159,077,195 159,079,003 RGD:7242757
G Larp7 La ribonucleoprotein domain family, member 7 JBrowse link 2 231,866,888 231,882,002 RGD:1624291
G Lsm10 LSM10, U7 small nuclear RNA associated JBrowse link 5 144,106,339 144,108,703 RGD:1600115
RGD:1624291
G Lsm11 LSM11, U7 small nuclear RNA associated JBrowse link 10 31,023,561 31,041,700 RGD:1600115
RGD:1624291
G Mepce methylphosphate capping enzyme JBrowse link 12 21,721,246 21,725,965 RGD:1624291
G Plcb1 phospholipase C beta 1 JBrowse link 3 127,721,244 128,419,565 RGD:1600115
RGD:1624291
G Plrg1 pleiotropic regulator 1 JBrowse link 2 182,040,338 182,056,669 RGD:1600115
RGD:1624291
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C JBrowse link 3 66,673,060 66,783,501 RGD:1600115
RGD:1624291
G Rdx radixin JBrowse link 8 56,570,728 56,612,851 RGD:1600115
RGD:1624291
G Rpl17 ribosomal protein L17 JBrowse link 18 70,969,733 70,972,839 RGD:11035308
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:11038675
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 JBrowse link 15 7,402,210 7,928,320 RGD:1600115
RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA activated, catalytic polypeptide JBrowse link 11 89,293,547 89,510,948 RGD:1600115
RGD:1624291
traversing start control point of mitotic cell cycle term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1600115
RGD:1624291
G Mtbp MDM2 binding protein JBrowse link 7 95,309,928 95,392,418 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 500767
    cellular process 314024
      cell cycle process 8044
        cell cycle phase transition 1838
          mitotic cell cycle phase transition 1709
            G1/S transition of mitotic cell cycle 793
              regulation of G1/S transition of mitotic cell cycle 456
                negative regulation of G1/S transition of mitotic cell cycle + 263
                positive regulation of G1/S transition of mitotic cell cycle + 91
                regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 37
Path 2
Term Annotations click to browse term
  biological_process 500767
    cellular process 314024
      single-organism cellular process 184248
        cell cycle 9820
          cell cycle process 8044
            mitotic cell cycle process 4212
              mitotic cell cycle phase transition 1709
                regulation of mitotic cell cycle phase transition 1048
                  regulation of G1/S transition of mitotic cell cycle 456
                    negative regulation of G1/S transition of mitotic cell cycle + 263
                    positive regulation of G1/S transition of mitotic cell cycle + 91
                    regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle + 37
paths to the root