ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of G1/S transition of mitotic cell cycle
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Accession:GO:2000045 term browser browse the term
Definition:Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
Comment:Note that this process is usually achieved by the regulation of the G1 cyclin-dependent protein kinase, consider annotating to the child term 'regulation of cyclin-dependent protein kinase activity involved in G1/S ; GO:0031657'.


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regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bid BH3 interacting domain death agonist GBrowse link 4 220,531,866 220,554,360 RGD:1600115
RGD:1624291
G Ccnd1 cyclin D1 GBrowse link 1 224,960,136 224,969,658 RGD:1624291
G E2f1 E2F transcription factor 1 GBrowse link 3 156,435,530 156,446,390 RGD:1600115
RGD:1624291
G Ecd ecdysoneless homolog (Drosophila) GBrowse link 15 8,500,863 8,531,884 RGD:1600115
RGD:1624291
G Id2 inhibitor of DNA binding 2 GBrowse link 6 53,084,391 53,086,222 RGD:1600115
RGD:1624291
G Ino80 INO80 complex subunit GBrowse link 3 117,737,293 117,817,221 RGD:1600115
RGD:1624291
G Kif14 kinesin family member 14 GBrowse link 13 58,400,186 58,466,702 RGD:1624291
G Pdpn podoplanin GBrowse link 5 165,646,114 165,679,595 RGD:1600115
RGD:1624291
G Pid1 phosphotyrosine interaction domain containing 1 GBrowse link 9 91,403,609 91,419,329 RGD:1600115
RGD:1624291
G Plk5 polo-like kinase 5 GBrowse link 7 12,382,705 12,391,125 RGD:1600115
RGD:1624291
G Ptpla protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a GBrowse link 17 82,917,839 82,940,613 RGD:1600115
RGD:1624291
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link 4 224,256,737 224,281,486 RGD:1600115
RGD:1624291
G Senp2 Sumo1/sentrin/SMT3 specific peptidase 2 GBrowse link 11 85,721,099 85,755,217 RGD:1600115
RGD:1624291
G Tcf3 transcription factor 3 GBrowse link 7 12,316,323 12,338,455 RGD:1600115
RGD:1624291
G Tjp3 tight junction protein 3 GBrowse link 7 11,463,323 11,481,943 RGD:1600115
RGD:1624291
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Casp2 caspase 2 GBrowse link 4 136,454,723 136,474,625 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link 20 8,592,437 8,602,879 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain GBrowse link 7 36,457,911 36,470,834 RGD:1600115
RGD:1624291
G LOC100911519 p53-induced protein with a death domain-like GBrowse link 1 221,331,932 221,341,685 RGD:1624291
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 60,719,023 60,743,581 RGD:1600115
RGD:1624291
G Muc1 mucin 1, cell surface associated GBrowse link 2 207,957,206 207,962,396 RGD:1624291
G Pml promyelocytic leukemia GBrowse link 8 62,778,563 62,810,283 RGD:1600115
RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link 6 143,942,657 144,077,935 RGD:1600115
RGD:1624291
G Rbm38 RNA binding motif protein 38 GBrowse link 3 177,104,361 177,116,965 RGD:1600115
RGD:1624291
G Sox4 SRY (sex determining region Y)-box 4 GBrowse link 17 39,476,956 39,481,662 RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 55,932,658 55,944,087 RGD:1624291
mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ccnd1 cyclin D1 GBrowse link 1 224,960,136 224,969,658 RGD:1600115
RGD:1624291
G Dgkz diacylglycerol kinase zeta GBrowse link 3 87,542,666 87,584,698 RGD:1600115
RGD:1624291
G Fbxo31 F-box protein 31 GBrowse link 19 64,224,819 64,363,108 RGD:1600115
RGD:1624291
G Gigyf2 GRB10 interacting GYF protein 2 GBrowse link 9 94,147,532 94,271,874 RGD:1600115
RGD:1624291
G LOC100910954 cellular tumor antigen p53-like GBrowse link 2 67,753,584 67,754,296 RGD:1600115
G LOC498414 LRRGT00197 RGD:1600115
G Rfwd3 ring finger and WD repeat domain 3 GBrowse link 19
19
53,787,638
54,289,116
53,798,031
54,310,716
RGD:1624291
G Rpa2 replication protein A2 GBrowse link 5 154,623,986 154,634,568 RGD:1600115
RGD:1624291
G Rps27l ribosomal protein S27-like GBrowse link 8 77,073,998 77,078,933 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 GBrowse link 10 55,932,658 55,944,087 RGD:1600115
RGD:1624291
G Tp63 tumor protein p63 GBrowse link 11 82,262,234 82,484,354 RGD:1600115
G Tp73 tumor protein p73 GBrowse link 5
5
174,889,051
174,843,033
174,901,875
174,868,415
RGD:1600115
negative regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link 13 31,758,213 31,920,775 RGD:1600115
RGD:1624291
G Brd7 bromodomain containing 7 GBrowse link 19 30,698,139 30,726,814 RGD:1600115
RGD:1624291
G Btn2a2 butyrophilin, subfamily 2, member A2 GBrowse link 17 45,723,229 45,734,752 RGD:1624291
G Cdc73 cell division cycle 73 GBrowse link 13 65,392,579 65,485,175 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A GBrowse link 20 8,592,437 8,602,879 RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) GBrowse link 5 111,817,188 111,826,334 RGD:1600115
RGD:1624291
G Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 GBrowse link 9 81,437,162 81,442,528 RGD:1624291
G Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 GBrowse link 7 70,460,026 70,468,044 RGD:1624291
G Ctdspl CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like GBrowse link 8 126,919,687 126,943,278 RGD:1624291
G Dact1 dishevelled-binding antagonist of beta-catenin 1 GBrowse link 6 103,201,826 103,212,384 RGD:1600115
RGD:1624291
G E2f7 E2F transcription factor 7 GBrowse link 7 53,286,853 53,328,709 RGD:1600115
RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit GBrowse link 4 141,955,864 142,018,471 RGD:1600115
RGD:1624291
G Fbxo7 F-box protein 7 GBrowse link 7 23,964,601 23,993,030 RGD:1600115
RGD:1624291
G Fhl1 four and a half LIM domains 1 GBrowse link X 153,743,208 153,803,160 RGD:1600115
RGD:1624291
G Gsg2 germ cell associated 2 (haspin) GBrowse link 10 59,434,870 59,437,669 RGD:1600115
RGD:1624291
G Jade1 jade family PHD finger 1 GBrowse link 2 148,061,324 148,114,469 RGD:1600115
RGD:1624291
G Kank2 KN motif and ankyrin repeat domains 2 GBrowse link 8 22,846,154 22,875,574 RGD:1600115
RGD:1624291
G Mir26a microRNA 26a GBrowse link 8 126,931,592 126,931,681 RGD:1624291
G Myo16 myosin XVI GBrowse link 16
16
84,026,826
84,230,049
84,196,088
84,387,681
RGD:8554212
G Pkd2 polycystic kidney disease 2 (autosomal dominant) GBrowse link 14 6,581,342 6,624,595 RGD:1600115
RGD:1624291
G Ppp2r3b protein phosphatase 2, regulatory subunit B'', beta GBrowse link 14 1,472,151 1,478,799 RGD:1624291
G Prmt2 protein arginine methyltransferase 2 GBrowse link 20 15,350,261 15,366,947 RGD:1624291
G Pten phosphatase and tensin homolog GBrowse link 1 258,651,829 258,717,009 RGD:1600115
RGD:1624291
G Rb1 retinoblastoma 1 GBrowse link 15 58,804,731 58,931,886 RGD:1600115
RGD:1624291
G Zc3h12d zinc finger CCCH type containing 12D GBrowse link 1 3,634,641 3,669,534 RGD:1600115
RGD:1624291
G Zfp655 zinc finger protein 655 GBrowse link 12 13,866,656 13,871,133 RGD:1600115
RGD:1624291
negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Nacc2 NACC family member 2, BEN and BTB (POZ) domain containing GBrowse link 3 8,869,877 8,936,580 RGD:1600115
RGD:1624291
positive regulation of G1/S transition of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Aif1 allograft inflammatory factor 1 GBrowse link 20 7,234,609 7,240,454 RGD:1600115
RGD:1624291
G Ankrd17 ankyrin repeat domain 17 GBrowse link 14 19,199,983 19,337,852 RGD:1624291
G Anp32b acidic (leucine-rich) nuclear phosphoprotein 32 family, member B GBrowse link 5 66,592,162 66,624,323 RGD:633716
G Anxa1 annexin A1 GBrowse link 1 245,192,875 245,220,057 RGD:1600115
RGD:1624291
G Apex1 APEX nuclease (multifunctional DNA repair enzyme) 1 GBrowse link 15 31,682,368 31,684,508 RGD:2315680
G Cdc45 cell division cycle 45 GBrowse link 11 89,431,161 89,456,065 RGD:1600115
G Crebbp CREB binding protein GBrowse link 10 10,349,914 10,475,506 RGD:2316124
G Cul4a cullin 4A GBrowse link 16 81,204,989 81,242,020 RGD:1600115
RGD:1624291
G Cul4b cullin 4B GBrowse link X 124,915,933 124,954,871 RGD:1600115
RGD:1624291
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 GBrowse link 8 62,249,046 62,255,081 RGD:2306669
G Ddx3y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked GBrowse link 13 110,058,379 110,061,548 RGD:1624291
G Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 GBrowse link 4 226,075,051 226,076,859 RGD:7242757
G Larp7 La ribonucleoprotein domain family, member 7 GBrowse link 2 251,212,469 251,227,583 RGD:1624291
G LOC100910540 7SK snRNA methylphosphate capping enzyme-like GBrowse link 12 23,998,765 24,003,520 RGD:1624291
G Lsm10 LSM10, U7 small nuclear RNA associated GBrowse link 5 147,876,104 147,878,239 RGD:1624291
G Lsm11 LSM11, U7 small nuclear RNA associated GBrowse link 10 30,844,898 30,862,998 RGD:1624291
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 134,211,557 134,908,321 RGD:1600115
RGD:1624291
G Plrg1 pleiotropic regulator 1 GBrowse link 2 201,454,958 201,471,289 RGD:1600115
RGD:1624291
G Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C GBrowse link 3 73,232,214 73,334,814 RGD:1600115
RGD:1624291
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 GBrowse link 15 11,469,650 11,995,676 RGD:1624291
signal transduction involved in mitotic G1 DNA damage checkpoint term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Prkdc protein kinase, DNA activated, catalytic polypeptide GBrowse link 11 92,347,175 92,565,022 RGD:1600115
RGD:1624291
traversing start control point of mitotic cell cycle term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 60,719,023 60,743,581 RGD:1600115
RGD:1624291
G Mtbp MDM2 binding protein GBrowse link 7 95,931,981 96,014,454 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 464782
    regulation of biological process 169919
      regulation of cellular process 145150
        regulation of cell cycle 4082
          regulation of mitotic cell cycle 1678
            regulation of mitotic cell cycle phase transition 978
              regulation of G1/S transition of mitotic cell cycle 392
                negative regulation of G1/S transition of mitotic cell cycle + 252
                positive regulation of G1/S transition of mitotic cell cycle + 78
Path 2
Term Annotations click to browse term
  biological_process 464782
    cellular process 290638
      single-organism cellular process 188632
        cell cycle 8732
          cell cycle process 6540
            cell cycle phase transition 1736
              mitotic cell cycle phase transition 1673
                G1/S transition of mitotic cell cycle 809
                  regulation of G1/S transition of mitotic cell cycle 392
                    negative regulation of G1/S transition of mitotic cell cycle + 252
                    positive regulation of G1/S transition of mitotic cell cycle + 78
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