ONTOLOGY REPORT - ANNOTATIONS


Term:detoxification
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Accession:GO:0098754 term browser browse the term
Definition:Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.


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aflatoxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akr7a3 aldo-keto reductase family 7 member A3 JBrowse link 5 157,801,120 157,813,756 RGD:1304380
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:12910550
cellular detoxification of nitrogen compound term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:1624291
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1624291
RGD:1600115
G Gstm3 glutathione S-transferase mu 3 JBrowse link 2 210,685,204 210,688,273 RGD:1624291
G Gstm5 glutathione S-transferase, mu 5 JBrowse link 2 210,685,338 210,688,133 RGD:1624291
G Gstm7 glutathione S-transferase, mu 7 JBrowse link 2 210,720,719 210,726,179 RGD:1600115
cellular oxidant detoxification term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aaed1 AhpC/TSA antioxidant enzyme domain containing 1 JBrowse link 17 1,798,224 1,830,011 RGD:1600115
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:1600115
G Apom apolipoprotein M JBrowse link 20 5,120,473 5,123,073 RGD:1600115
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:1600115
G Clic2 chloride intracellular channel 2 JBrowse link 20 295,338 310,363 RGD:1600115
G Cygb cytoglobin JBrowse link 10 105,618,325 105,628,091 RGD:1600115
G Duox1 dual oxidase 1 JBrowse link 3 114,251,794 114,286,827 RGD:1600115
G Duox2 dual oxidase 2 JBrowse link 3 114,218,187 114,237,808 RGD:1600115
G Epx eosinophil peroxidase JBrowse link 10 75,160,690 75,171,774 RGD:1600115
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1600115
G Fam213a family with sequence similarity 213, member A JBrowse link 16 17,494,000 17,513,781 RGD:1600115
G Fam213b family with sequence similarity 213, member B JBrowse link 5 172,304,799 172,307,402 RGD:1600115
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:1600115
G Gpx2 glutathione peroxidase 2 JBrowse link 6 99,839,960 99,843,245 RGD:1600115
G Gpx3 glutathione peroxidase 3 JBrowse link 10 40,247,436 40,255,423 RGD:1600115
G Gpx4 glutathione peroxidase 4 JBrowse link 7 12,516,357 12,519,154 RGD:1600115
G Gpx5 glutathione peroxidase 5 JBrowse link 17 45,508,657 45,518,686 RGD:1600115
G Gpx6 glutathione peroxidase 6 JBrowse link 17 45,439,268 45,446,952 RGD:1600115
G Gpx7 glutathione peroxidase 7 JBrowse link 5 128,001,766 128,009,610 RGD:1600115
G Gpx8 glutathione peroxidase 8 JBrowse link 2 44,903,337 44,907,046 RGD:1600115
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:1600115
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:1600115
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:1600115
G Gsta3 glutathione S-transferase alpha 3 JBrowse link 9 27,357,490 27,417,023 RGD:1600115
G Gstk1 glutathione S-transferase kappa 1 JBrowse link 4 71,621,777 71,626,096 RGD:1600115
G Gstm2 glutathione S-transferase mu 2 JBrowse link 2 210,778,041 210,782,807 RGD:1600115
G Gstm7 glutathione S-transferase, mu 7 JBrowse link 2 210,720,719 210,726,179 RGD:1600115
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1600115
G Gsto2 glutathione S-transferase omega 2 JBrowse link 1 267,617,517 267,640,455 RGD:1600115
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:1600115
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:1600115
G Gstt2 glutathione S-transferase, theta 2 JBrowse link 20 13,760,810 13,764,481 RGD:1600115
G Hba-a1 hemoglobin alpha, adult chain 1 JBrowse link 10 15,602,794 15,603,649 RGD:1600115
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:1600115
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:1600115
G Hp haptoglobin JBrowse link 19 42,096,255 42,100,805 RGD:1600115
G Iyd iodotyrosine deiodinase JBrowse link 1 40,086,513 40,100,966 RGD:1600115
G Kdm3b lysine demethylase 3B JBrowse link 18 27,593,823 27,631,129 RGD:1600115
G LOC103690044 glutathione S-transferase omega-2 JBrowse link 1 271,228,018 271,243,517 RGD:1600115
G LOC108348061 glutathione S-transferase alpha-3 JBrowse link 9 27,436,255 27,452,897 RGD:1600115
G Lpo lactoperoxidase JBrowse link 10 75,100,385 75,120,247 RGD:1600115
G Ltc4s leukotriene C4 synthase JBrowse link 10 35,736,486 35,743,088 RGD:1600115
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:1600115
G Mgst2 microsomal glutathione S-transferase 2 JBrowse link 2 140,708,396 140,727,381 RGD:1600115
G Mgst3 microsomal glutathione S-transferase 3 JBrowse link 13 85,601,499 85,622,392 RGD:1600115
G Nxn nucleoredoxin JBrowse link 10 64,411,710 64,550,147 RGD:1600115
G Nxnl1 nucleoredoxin-like 1 JBrowse link 16 19,992,211 19,996,815 RGD:1600115
G Nxnl2 nucleoredoxin-like 2 JBrowse link 17 14,053,896 14,058,642 RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1600115
G Prdx3 peroxiredoxin 3 JBrowse link 1 282,238,774 282,251,193 RGD:1600115
G Prdx4 peroxiredoxin 4 JBrowse link X 43,495,453 43,512,994 RGD:1600115
G Prdx5 peroxiredoxin 5 JBrowse link 1 222,164,462 222,167,447 RGD:1600115
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:1624291
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:1600115
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:1600115
G Pxdn peroxidasin JBrowse link 6 48,866,496 48,982,368 RGD:1600115
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:1600115
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:1600115
G Selenof selenoprotein F JBrowse link 2 250,600,823 250,633,903 RGD:1600115
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1600115
G Selenot selenoprotein T JBrowse link 2 148,765,412 148,781,080 RGD:12793008
G Selenow selenoprotein W JBrowse link 1 77,530,692 77,535,765 RGD:1600115
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:1624291
G Sesn2 sestrin 2 JBrowse link 5 150,684,891 150,703,846 RGD:1624291
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:1600115
G Tpo thyroid peroxidase JBrowse link 6 49,020,918 49,089,855 RGD:1600115
G Txn1 thioredoxin 1 JBrowse link 5 75,049,735 75,057,731 RGD:1600115
G Txndc17 thioredoxin domain containing 17 JBrowse link 10 58,776,792 58,779,764 RGD:1600115
G Txndc2 thioredoxin domain containing 2 JBrowse link 9 113,354,047 113,358,558 RGD:1600115
G Txndc8 thioredoxin domain containing 8 JBrowse link 5 75,088,063 75,116,427 RGD:1600115
G Txnl1 thioredoxin-like 1 JBrowse link 18 59,056,454 59,086,278 RGD:1600115
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:1600115
G Txnrd2 thioredoxin reductase 2 JBrowse link 11 86,667,994 86,716,063 RGD:1600115
G Txnrd3 thioredoxin reductase 3 JBrowse link 4 121,612,332 121,650,543 RGD:1600115
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link 5 165,247,630 165,259,228 RGD:1600115
detoxification of cadmium ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc30a1 solute carrier family 30 member 1 JBrowse link 13 110,677,810 110,681,683 RGD:8554228
detoxification of copper ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:1624291
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1600115
RGD:1624291
detoxification of mercury ion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1600115
RGD:1624291
formaldehyde catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide JBrowse link 2 243,728,500 243,740,907 RGD:1624291
G Esd esterase D JBrowse link 15 56,756,848 56,776,348 RGD:1600115
guanine deglycation, methylglyoxal removal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
mercury ion transport term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:11081013
phenylacetate catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pon3 paraoxonase 3 JBrowse link 4 30,311,981 30,338,679 RGD:1303961
positive regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Rgn regucalcin JBrowse link X 1,833,484 1,848,904 RGD:9590277
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
regulation of removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:1624291
G Fbln5 fibulin 5 JBrowse link 6 125,644,797 125,723,957 RGD:1624291
G Gch1 GTP cyclohydrolase 1 JBrowse link 15 23,935,011 23,968,971 RGD:1624291
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:1624291
regulation of superoxide dismutase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Szt2 SZT2, KICSTOR complex subunit JBrowse link 5 137,192,120 137,238,384 RGD:8554220
RGD:1624291
removal of superoxide radicals term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1624291
RGD:1600115
G Atp7a ATPase copper transporting alpha JBrowse link X 77,076,085 77,193,644 RGD:1624291
G Ccs copper chaperone for superoxide dismutase JBrowse link 1 220,075,251 220,096,319 RGD:1600115
G Fancc Fanconi anemia, complementation group C JBrowse link 17 826,512 955,703 RGD:1624291
RGD:1600115
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:1624291
G Mt3 metallothionein 3 JBrowse link 19 11,324,708 11,326,112 RGD:1624291
RGD:1600115
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:1624291
RGD:1600115
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:1600115
G Prdx1 peroxiredoxin 1 JBrowse link 5 135,536,413 135,551,986 RGD:1624291
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:1624291
RGD:1600115
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:730094
RGD:8655968
RGD:1600115
RGD:1624291
RGD:1601266
RGD:634854
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:2291939
RGD:2291946
RGD:2317387
RGD:1624291
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:1600115
toxin catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:1600115
G Gsto2 glutathione S-transferase omega 2 JBrowse link 1 267,617,517 267,640,455 RGD:1600115
G LOC103690044 glutathione S-transferase omega-2 JBrowse link 1 271,228,018 271,243,517 RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17463
    detoxification 107
      cellular detoxification + 101
      detoxification of arsenic-containing substance 0
      detoxification of inorganic compound + 6
      detoxification of nitrogen compound + 5
      detoxification of zinc ion 0
      mycothiol-dependent detoxification 0
      toxin catabolic process + 7
Path 2
Term Annotations click to browse term
  biological_process 17463
    response to stimulus 9332
      response to chemical 5712
        response to toxic substance 736
          detoxification 107
            cellular detoxification + 101
            detoxification of arsenic-containing substance 0
            detoxification of inorganic compound + 6
            detoxification of nitrogen compound + 5
            detoxification of zinc ion 0
            mycothiol-dependent detoxification 0
            toxin catabolic process + 7
paths to the root