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ONTOLOGY REPORT - ANNOTATIONS

Term:complement-dependent cytotoxicity
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Accession:GO:0097278 term browser browse the term
Definition:Cell killing caused by the membrane attack complex formed following complement activation.


show annotations for term's descendants           Sort by:
complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25284781)		 Ensembl
RGD		 PMID:25284781 GO_REF:0000107 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 involved_in ISO (PMID:11711607) RGD PMID:11711607 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Rab27a RAB27A, member RAS oncogene family involved_in ISO (PMID:24404184) RGD PMID:24404184 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
negative regulation of complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule IMP RGD PMID:28212662 RGD:13792592 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cldn5 claudin 5 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP oligodendrocyte precursor cells RGD PMID:16135098 RGD:10448271 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Il13 interleukin 13 involved_in ISO (PMID:16034134) RGD PMID:16034134 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:16034134)
(PMID:16034134), (PMID:24280217)		 RGD PMID:16034134 PMID:24280217 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
positive regulation of complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd5l Cd5 molecule-like acts_upstream_of_or_within ISO MGI:2653296 (PMID:25284781) RGD PMID:25284781 NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
regulation of complement-dependent cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) acts_upstream_of_or_within ISO (PMID:25284781) RGD PMID:25284781 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd59b CD59b molecule acts_upstream_of_or_within ISO (PMID:25284781) RGD PMID:25284781 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cdh5 cadherin 5 involved_in ISO (PMID:24280217) RGD PMID:24280217 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:25284781) RGD PMID:25284781 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (PMID:25284781) RGD PMID:25284781 NCBI chr13:106,606,952...106,660,442
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Il10 interleukin 10 NOT|involved_in ISO (PMID:16034134) RGD PMID:16034134 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il11 interleukin 11 NOT|involved_in ISO (PMID:16034134) RGD PMID:16034134 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 NOT|involved_in ISO (PMID:16034134) RGD PMID:16034134 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cell killing 251
        complement-dependent cytotoxicity 19
          negative regulation of complement-dependent cytotoxicity 7
          positive regulation of complement-dependent cytotoxicity 2
          regulation of complement-dependent cytotoxicity + 16
paths to the root