catalytic step 2 spliceosome - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	catalytic step 2 spliceosome	go back to main search page
Accession:	GO:0071013	browse the term
Definition:	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
Synonyms:	narrow_synonym:	mammalian spliceosomal complex C; mammalian spliceosomal complex C1; yeast spliceosomal complex A2-2

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catalytic step 2 spliceosome
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Aqr	aquarius homolog (mouse)		ISO	3	99,964,018	100,034,050	RGD:1624291	RGD
G	Aqr	aquarius homolog (mouse)		IEA	3	99,964,018	100,034,050	RGD:1600115	ENSEMBL
G	Cactin	cactin, spliceosome C complex subunit		ISO	7	9,875,757	9,880,563	RGD:1624291	RGD
G	Cdc40	cell division cycle 40		ISO	20	44,952,482	44,974,587	RGD:1624291	RGD
G	Cdc40	cell division cycle 40		IEA	20	44,952,482	44,974,587	RGD:1600115	ENSEMBL
G	Cdc5l	cell division cycle 5-like		ISO	9	11,165,631	11,204,135	RGD:1624291	RGD
G	Cdc5l	cell division cycle 5-like		IEA	9	11,165,631	11,204,135	RGD:1600115	ENSEMBL
G	Crnkl1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)		IEA	3	134,538,940	134,554,660	RGD:1600115	ENSEMBL
G	Crnkl1-ps1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila) pseudogene		ISO				RGD:1624291	RGD
G	Cwc15	CWC15 spliceosome-associated protein homolog (S. cerevisiae)		ISO	8	11,248,219	11,259,120	RGD:1624291	RGD
G	Cwc22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)		ISO	3	60,560,959	60,600,491	RGD:1624291	RGD
G	Cwc27	CWC27 spliceosome-associated protein homolog (S. cerevisiae)		ISO	2	35,567,205	35,825,390	RGD:1624291	RGD
G	Cwc27	CWC27 spliceosome-associated protein homolog (S. cerevisiae)		IEA	2	35,567,205	35,825,390	RGD:1600115	ENSEMBL
G	Ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23		IEA	7	137,394,834	137,412,075	RGD:1600115	ENSEMBL
G	Ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23		ISO	7	137,394,834	137,412,075	RGD:1624291	RGD
G	Ddx41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41		IEA	17	15,147,008	15,152,401	RGD:1600115	ENSEMBL
G	Ddx41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41		ISO	17	15,147,008	15,152,401	RGD:1624291	RGD
G	Ddx5	DEAD (Asp-Glu-Ala-Asp) box helicase 5		ISO	10	96,131,888	96,139,423	RGD:1624291	RGD
G	Ddx5	DEAD (Asp-Glu-Ala-Asp) box helicase 5		IEA	10	96,131,888	96,139,423	RGD:1600115	ENSEMBL
G	Dgcr14	DiGeorge syndrome critical region gene 14		ISO	11	85,064,074	85,072,979	RGD:1624291	RGD
G	Dgcr14	DiGeorge syndrome critical region gene 14		IEA	11	85,064,074	85,072,979	RGD:1600115	ENSEMBL
G	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35		IEA	3	149,532,510	149,589,678	RGD:1600115	ENSEMBL
G	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35		ISO	3	149,532,510	149,589,678	RGD:1624291	RGD
G	Dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38		IEA	19	39,416,281	39,433,530	RGD:1600115	ENSEMBL
G	Dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38		ISO	19	39,416,281	39,433,530	RGD:1624291	RGD
G	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8		ISO	10	90,769,567	90,806,827	RGD:1624291	RGD
G	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8		IEA	10	90,769,567	90,806,827	RGD:1600115	ENSEMBL
G	Eftud2	elongation factor Tu GTP binding domain containing 2		ISO	10	92,012,161	92,053,043	RGD:1624291	RGD
G	Eftud2	elongation factor Tu GTP binding domain containing 2		IEA	10	92,012,161	92,053,043	RGD:1600115	ENSEMBL
G	Eif4a3	eukaryotic translation initiation factor 4A, isoform 3		IEA				RGD:1600115	ENSEMBL
G	Frg1	FSHD region gene 1		ISO	16	54,237,736	54,259,311	RGD:1624291	RGD
G	Gpatch1	G patch domain containing 1		IEA	1	87,793,196	87,833,003	RGD:1600115	ENSEMBL
G	Gpatch1	G patch domain containing 1		ISO	1	87,793,196	87,833,003	RGD:1624291	RGD
G	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1		ISO	7	142,150,229	142,154,520	RGD:1624291	RGD
G	Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1		ISO	4	79,700,327	79,704,116	RGD:1624291	RGD
G	Hnrnpa2b1	heterogeneous nuclear ribonucleoprotein A2/B1		IEA	4	79,700,327	79,704,116	RGD:1600115	ENSEMBL
G	Hnrnpa3	heterogeneous nuclear ribonucleoprotein A3		ISO	3	68,872,863	68,875,337	RGD:1624291	RGD
G	Hnrnpc	heterogeneous nuclear ribonucleoprotein C (C1/C2)		ISO	15	27,516,839	27,546,646	RGD:1624291	RGD
G	Hnrnpf	heterogeneous nuclear ribonucleoprotein F		ISO	4	154,207,198	154,228,398	RGD:1624291	RGD
G	Hnrnpk	heterogeneous nuclear ribonucleoprotein K		ISO	17	12,196,630	12,205,720	RGD:1624291	RGD
G	Hnrnpm	heterogeneous nuclear ribonucleoprotein M		ISO	7	16,150,060	16,188,054	RGD:1624291	RGD
G	Hnrnpr	heterogeneous nuclear ribonucleoprotein R		ISO	5	155,053,567	155,086,482	RGD:1624291	RGD
G	Hnrnpu	heterogeneous nuclear ribonucleoprotein U		ISO	13	93,978,865	93,987,654	RGD:1624291	RGD
G	Hnrnpu	heterogeneous nuclear ribonucleoprotein U		IEA	13	93,978,865	93,987,654	RGD:1600115	ENSEMBL
G	Hnrph1	heterogeneous nuclear ribonucleoprotein H1		IEA	10	35,922,840	35,930,132	RGD:1600115	ENSEMBL
G	Isy1	ISY1 splicing factor homolog (S. cerevisiae)		ISO	4	122,006,785	122,027,475	RGD:1624291	RGD
G	LOC100360635	small nuclear ribonucleoprotein polypeptide G-like		IEA	14	83,820,196	83,820,426	RGD:1600115	ENSEMBL
G	LOC100362099	small nuclear ribonucleoprotein polypeptide E-like		IEA	1	135,543,220	135,543,498	RGD:1600115	ENSEMBL
G	LOC100364748	U2 small nuclear ribonucleoprotein polypeptide A-like		IEA				RGD:1600115	ENSEMBL
G	LOC100911683	small nuclear ribonucleoprotein G-like		IEA				RGD:1600115	ENSEMBL
G	LOC687575	similar to Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 snRNP auxiliary factor small subunit)		IEA				RGD:1600115	ENSEMBL
G	Lsm2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)		IEA				RGD:1600115	ENSEMBL
G	Lsm3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)		ISO	4	125,700,026	125,706,270	RGD:1624291	RGD
G	Lsm3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)		IEA	4	125,700,026	125,706,270	RGD:1600115	ENSEMBL
G	Magoh	mago-nashi homolog, proliferation-associated (Drosophila)		ISO	5	128,982,276	128,989,724	RGD:1624291	RGD
G	Magoh	mago-nashi homolog, proliferation-associated (Drosophila)		IEA	5	128,982,276	128,989,724	RGD:1600115	ENSEMBL
G	Pabpc1	poly(A) binding protein, cytoplasmic 1		ISO	7	72,116,140	72,128,433	RGD:1624291	RGD
G	Plrg1	pleiotropic regulator 1		ISO	2	174,780,415	174,796,746	RGD:1624291	RGD
G	Plrg1	pleiotropic regulator 1		IEA	2	174,780,415	174,796,746	RGD:1600115	ENSEMBL
G	Pnn	pinin, desmosome associated protein		IEA	6	79,759,026	79,767,339	RGD:1600115	ENSEMBL
G	Pnn	pinin, desmosome associated protein		ISO	6	79,759,026	79,767,339	RGD:1624291	RGD
G	Ppie	peptidylprolyl isomerase E (cyclophilin E)		ISO	5	142,445,476	142,455,367	RGD:1624291	RGD
G	Ppil1	peptidylprolyl isomerase (cyclophilin)-like 1		ISO	20	7,548,896	7,565,640	RGD:1624291	RGD
G	Ppil3	peptidylprolyl isomerase (cyclophilin)-like 3		ISO	9	57,089,457	57,103,114	RGD:1624291	RGD
G	Ppil3	peptidylprolyl isomerase (cyclophilin)-like 3		IEA	9	57,089,457	57,103,114	RGD:1600115	ENSEMBL
G	Ppwd1	peptidylprolyl isomerase domain and WD repeat containing 1		IEA	2	35,136,458	35,159,485	RGD:1600115	ENSEMBL
G	Ppwd1	peptidylprolyl isomerase domain and WD repeat containing 1		ISO	2	35,136,458	35,159,485	RGD:1624291	RGD
G	Prpf19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)		ISO	1	213,390,564	213,401,943	RGD:1624291	RGD
G	Prpf19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)		IEA	1	213,390,564	213,401,943	RGD:1600115	ENSEMBL
G	Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)		ISO	17	36,319,606	36,350,616	RGD:1624291	RGD
G	Prpf4b	PRP4 pre-mRNA processing factor 4 homolog B (yeast)		IEA	17	36,319,606	36,350,616	RGD:1600115	ENSEMBL
G	Prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)		ISO	3	170,740,406	170,804,674	RGD:1624291	RGD
G	Prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)		IEA	3	170,740,406	170,804,674	RGD:1600115	ENSEMBL
G	Prpf8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)		ISO	10	62,786,225	62,830,939	RGD:1624291	RGD
G	Prpf8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)		IEA	10	62,786,225	62,830,939	RGD:1600115	ENSEMBL
G	Raly	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))		IEA	3	145,275,832	145,337,808	RGD:1600115	ENSEMBL
G	Raly	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))		ISO	3	145,275,832	145,337,808	RGD:1624291	RGD
G	Rbm22	RNA binding motif protein 22		ISO	18	56,509,140	56,519,948	RGD:1624291	RGD
G	Rbm22	RNA binding motif protein 22		IEA	18	56,509,140	56,519,948	RGD:1600115	ENSEMBL
G	Rbm8a	RNA binding motif protein 8A		ISO	2	191,429,805	191,432,261	RGD:1624291	RGD
G	Rbm8a	RNA binding motif protein 8A		IEA	2	191,429,805	191,432,261	RGD:1600115	ENSEMBL
G	Rbmx	RNA binding motif protein, X-linked		ISO	X	142,112,807	142,119,267	RGD:1624291	RGD
G	Rbmxrtl	RNA binding motif protein, X chromosome retrogene-like		ISS	19	31,310,317	31,313,892	RGD:1600115	UniProtKB
G	Sart1	squamous cell carcinoma antigen recognized by T cells		ISO	1	208,026,619	208,035,281	RGD:1624291	RGD
G	Sart1	squamous cell carcinoma antigen recognized by T cells		IEA	1	208,026,619	208,035,281	RGD:1600115	ENSEMBL
G	Sf3a1	splicing factor 3a, subunit 1		IEA	14	84,786,072	84,806,825	RGD:1600115	ENSEMBL
G	Sf3a1	splicing factor 3a, subunit 1		ISO	14	84,786,072	84,806,825	RGD:1624291	RGD
G	Sf3a2	splicing factor 3a, subunit 2		ISO	7	10,419,996	10,426,019	RGD:1624291	RGD
G	Sf3a3	splicing factor 3a, subunit 3		ISO	5	144,040,061	144,059,690	RGD:1624291	RGD
G	Sf3a3	splicing factor 3a, subunit 3		IEA	5	144,040,061	144,059,690	RGD:1600115	ENSEMBL
G	Sf3b1	splicing factor 3b, subunit 1		ISO	9	53,796,176	53,837,297	RGD:1624291	RGD
G	Sf3b1	splicing factor 3b, subunit 1		IEA	9	53,796,176	53,837,297	RGD:1600115	ENSEMBL
G	Sf3b3	splicing factor 3b, subunit 3		ISO	19	40,730,284	40,765,321	RGD:1624291	RGD
G	Skiv2l2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)		ISO	2	44,247,683	44,306,293	RGD:1624291	RGD
G	Slu7	SLU7 splicing factor homolog (S. cerevisiae)		IEA	10	28,536,630	28,551,427	RGD:1600115	ENSEMBL
G	Snrnp200	small nuclear ribonucleoprotein 200 (U5)		ISO	3	114,708,628	114,738,549	RGD:1624291	RGD
G	Snrnp200	small nuclear ribonucleoprotein 200 (U5)		IEA	3	114,708,628	114,738,549	RGD:1600115	ENSEMBL
G	Snrnp40	small nuclear ribonucleoprotein 40 (U5)		ISO	5	149,388,592	149,422,973	RGD:1624291	RGD
G	Snrpa1	small nuclear ribonucleoprotein polypeptide A'		ISO	1	120,490,921	120,503,974	RGD:1624291	RGD
G	Snrpa1	small nuclear ribonucleoprotein polypeptide A'		IEA	1	120,490,921	120,503,974	RGD:1600115	ENSEMBL
G	Snrpb	small nuclear ribonucleoprotein polypeptides B and B1		ISO	3	117,770,454	117,778,063	RGD:1624291	RGD
G	Snrpb	small nuclear ribonucleoprotein polypeptides B and B1		IEA	3	117,770,454	117,778,063	RGD:1600115	ENSEMBL
G	Snrpb2	small nuclear ribonucleoprotein polypeptide B''		ISO	3	131,416,677	131,426,007	RGD:1624291	RGD
G	Snrpb2	small nuclear ribonucleoprotein polypeptide B''		IEA	3	131,416,677	131,426,007	RGD:1600115	ENSEMBL
G	Snrpd1	small nuclear ribonucleoprotein D1		ISO	18	2,001,140	2,011,674	RGD:1624291	RGD
G	Snrpd1	small nuclear ribonucleoprotein D1		IEA	18	2,001,140	2,011,674	RGD:1600115	ENSEMBL
G	Snrpd2	small nuclear ribonucleoprotein D2 polypeptide		ISO	1	78,509,142	78,511,992	RGD:1624291	RGD
G	Snrpd2	small nuclear ribonucleoprotein D2 polypeptide		IEA	1	78,509,142	78,511,992	RGD:1600115	ENSEMBL
G	Snrpe	small nuclear ribonucleoprotein polypeptide E		ISO	13	46,522,340	46,528,589	RGD:1624291	RGD
G	Snrpf	small nuclear ribonucleoprotein polypeptide F		ISO	7	30,644,564	30,651,266	RGD:1624291	RGD
G	Snrpf	small nuclear ribonucleoprotein polypeptide F		IEA	7	30,644,564	30,651,266	RGD:1600115	ENSEMBL
G	Snrpg	small nuclear ribonucleoprotein polypeptide G		IEA	4	120,549,595	120,557,144	RGD:1600115	ENSEMBL
G	Snrpg	small nuclear ribonucleoprotein polypeptide G		ISO	4	120,549,595	120,557,144	RGD:1624291	RGD
G	Snw1	SNW domain containing 1		ISO	6	111,688,742	111,712,826	RGD:1624291	RGD
G	Snw1	SNW domain containing 1		IEA	6	111,688,742	111,712,826	RGD:1600115	ENSEMBL
G	Srrm1	serine/arginine repetitive matrix 1		IEA	5	154,113,002	154,145,275	RGD:1600115	ENSEMBL
G	Srrm1	serine/arginine repetitive matrix 1		ISO	5	154,113,002	154,145,275	RGD:1624291	RGD
G	Srsf1	serine/arginine-rich splicing factor 1		ISO	10	76,339,824	76,344,552	RGD:1624291	RGD
G	Srsf1	serine/arginine-rich splicing factor 1		IEA	10	76,339,824	76,344,552	RGD:1600115	ENSEMBL
G	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)		ISO	5	153,707,654	153,715,581	RGD:1624291	RGD
G	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)		IEA	5	153,707,654	153,715,581	RGD:1600115	ENSEMBL
G	Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein		ISO	8	93,730,131	93,820,288	RGD:1624291	RGD
G	Tfip11	tuftelin interacting protein 11		ISO	19	14,307,576	14,319,808	RGD:1624291	RGD
G	Tfip11	tuftelin interacting protein 11		IEA	19	14,307,576	14,319,808	RGD:1600115	ENSEMBL
G	Thoc4	THO complex 4		IEA	10	109,984,500	109,988,263	RGD:1600115	ENSEMBL
G	Wdr83	WD repeat domain 83		IEA	19	24,733,303	24,738,851	RGD:1600115	ENSEMBL
G	Wdr83	WD repeat domain 83		ISO	19	24,733,303	24,738,851	RGD:1624291	RGD
G	Xab2	XPA binding protein 2		ISO	12	2,533,687	2,545,690	RGD:1624291	RGD
G	Xab2	XPA binding protein 2		IEA	12	2,533,687	2,545,690	RGD:1600115	ENSEMBL
G	Zcchc8	zinc finger, CCHC domain containing 8		IEA	12	34,007,470	34,029,866	RGD:1600115	ENSEMBL
G	Zcchc8	zinc finger, CCHC domain containing 8		ISO	12	34,007,470	34,029,866	RGD:1624291	RGD

Term paths to the root

Path 1
Term	Annotations
cellular_component	76599
macromolecular complex	9662
ribonucleoprotein complex	1582
spliceosomal complex	271
catalytic step 2 spliceosome	131
U12-type catalytic step 2 spliceosome	0
U2-type catalytic step 2 spliceosome	0
Path 2
Term	Annotations
cellular_component	76599
cell	60574
cell part	60566
intracellular	47239
intracellular part	46471
intracellular organelle	34832
intracellular membrane-bounded organelle	28638
nucleus	15149
nuclear part	6383
spliceosomal complex	271
catalytic step 2 spliceosome	131
U12-type catalytic step 2 spliceosome	0
U2-type catalytic step 2 spliceosome	0