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Term:BRCA1-A complex
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Accession:GO:0070531 term browser browse the term
Definition:A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.


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BRCA1-A complex term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Babam1 BRISC and BRCA1 A complex member 1 GBrowse link ISO 16 18,558,063 18,564,094 RGD:1624291 RGD
G Babam1 BRISC and BRCA1 A complex member 1 GBrowse link ISO 16 18,558,063 18,564,094 RGD:1624291 RGD
G Babam1 BRISC and BRCA1 A complex member 1 GBrowse link ISO 16 18,558,063 18,564,094 RGD:1624291 RGD
G Babam1 BRISC and BRCA1 A complex member 1 GBrowse link ISS 16 18,558,063 18,564,094 RGD:1600115 UniProtKB
G Bard1 BRCA1 associated RING domain 1 GBrowse link IEA 9 70,120,151 70,198,591 RGD:1600115 ENSEMBL
G Bard1 BRCA1 associated RING domain 1 GBrowse link ISO 9 70,120,151 70,198,591 RGD:1624291 RGD
G Bard1 BRCA1 associated RING domain 1 GBrowse link ISO 9 70,120,151 70,198,591 RGD:1624291 RGD
G Bard1 BRCA1 associated RING domain 1 GBrowse link ISO 9 70,120,151 70,198,591 RGD:1624291 RGD
G Brca1 breast cancer 1, early onset GBrowse link ISO 10 90,513,630 90,572,676 RGD:1624291 RGD
G Brca1 breast cancer 1, early onset GBrowse link ISO 10 90,513,630 90,572,676 RGD:1624291 RGD
G Brca1 breast cancer 1, early onset GBrowse link ISO 10 90,513,630 90,572,676 RGD:1624291 RGD
G Brca1 breast cancer 1, early onset GBrowse link ISO 10 90,513,630 90,572,676 RGD:1624291 RGD
G Brca1 breast cancer 1, early onset GBrowse link ISO 10 90,513,630 90,572,676 RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISO RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISO RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISO RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISO RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISO RGD:1624291 RGD
G Brcc3 BRCA1/BRCA2-containing complex, subunit 3 ISS RGD:1600115 UniProtKB
G Bre brain and reproductive organ-expressed (TNFRSF1A modulator) GBrowse link ISO 6 24,406,837 24,791,918 RGD:1624291 RGD
G Bre brain and reproductive organ-expressed (TNFRSF1A modulator) GBrowse link ISO 6 24,406,837 24,791,918 RGD:1624291 RGD
G Bre brain and reproductive organ-expressed (TNFRSF1A modulator) GBrowse link ISO 6 24,406,837 24,791,918 RGD:1624291 RGD
G Bre brain and reproductive organ-expressed (TNFRSF1A modulator) GBrowse link ISO 6 24,406,837 24,791,918 RGD:1624291 RGD
G Bre brain and reproductive organ-expressed (TNFRSF1A modulator) GBrowse link ISS 6 24,406,837 24,791,918 RGD:1600115 UniProtKB
G Fam175a family with sequence similarity 175, member A GBrowse link ISO 14 10,080,191 10,094,528 RGD:1624291 RGD
G Fam175a family with sequence similarity 175, member A GBrowse link ISO 14 10,080,191 10,094,528 RGD:1624291 RGD
G Fam175a family with sequence similarity 175, member A GBrowse link ISO 14 10,080,191 10,094,528 RGD:1624291 RGD
G Fam175a family with sequence similarity 175, member A GBrowse link ISO 14 10,080,191 10,094,528 RGD:1624291 RGD
G Fam175a family with sequence similarity 175, member A GBrowse link IEA 14 10,080,191 10,094,528 RGD:1600115 ENSEMBL
G Fam175a family with sequence similarity 175, member A GBrowse link ISS 14 10,080,191 10,094,528 RGD:1600115 UniProtKB
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISO 17 15,579,709 15,644,888 RGD:1624291 RGD
G Uimc1 ubiquitin interaction motif containing 1 GBrowse link ISS 17 15,579,709 15,644,888 RGD:1600115 UniProtKB

Term paths to the root
Path 1
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  cellular_component 76568
    macromolecular complex 9661
      protein complex 7829
        BRCA1-A complex 37
Path 2
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  cellular_component 76568
    cell 60552
      cell part 60544
        intracellular 47229
          intracellular part 46462
            intracellular organelle 34824
              intracellular membrane-bounded organelle 28637
                nucleus 15146
                  nuclear part 6384
                    BRCA1-A complex 37
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