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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lymphocyte apoptotic process
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Accession:GO:0070229 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.
Comment:Note that a lymphocyte is a cell of the B cell, T cell, or natural killer cell lineage (CL:0000542).
Synonyms:exact_synonym: down regulation of lymphocyte apoptosis;   downregulation of lymphocyte apoptosis
 narrow_synonym: inhibition of lymphocyte apoptosis;   negative regulation of lymphocyte apoptosis


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negative regulation of lymphocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:2156165 (PMID:8170972) RGD PMID:8170972 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) RGD PMID:15632112 NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5908764|PMID:27745970)		 Ensembl
RGD		 PMID:27745970 GO_REF:0000107 MGI:5908764 NCBI chr 6:97,936,002...97,961,379
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO (MGI:2387354|PMID:10755614) RGD PMID:10755614 MGI:2387354 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISS
ISO		 GO_REF:0000024
(MGI:5291865|PMID:21876153)		 UniProt
RGD		 PMID:21876153 GO_REF:0000024 MGI:5291865 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2669956 (PMID:18971390)		 Ensembl
RGD		 PMID:18971390 GO_REF:0000107 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (MGI:2150820|PMID:11567634) RGD PMID:11567634 MGI:2150820 NCBI chr 5:166,606,909...166,609,599
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Tsc22d3 TSC22 domain family, member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:9430225)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:9430225 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:104,217,898...104,277,886
Ensembl chr  X:104,217,925...104,276,861 		JBrowse link
negative regulation of B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B involved_in ISO
IEA
ISS		 (PMID:20959462)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20959462 GO_REF:0000024 GO_REF:0000107 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8313913)		 Ensembl
RGD		 PMID:8313913 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:25267198) RGD PMID:25267198 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO (PMID:15569688) RGD PMID:15569688 NCBI chr16:17,630,519...17,649,932
Ensembl chr16:17,635,322...17,647,991 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:9184696) RGD PMID:9184696 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:7736574) RGD PMID:7736574 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) RGD PMID:15572028 MGI:4456946 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Mir106a microRNA 106a acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr  X:132,422,584...132,422,661
Ensembl chr  X:132,422,584...132,422,661 		JBrowse link
G Mir106b microRNA 106b acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425 		JBrowse link
G Mir19b1 microRNA 19b-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Mir20b microRNA 20b acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir25 microRNA 25 acts_upstream_of_or_within ISO (PMID:18329372) RGD PMID:18329372 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015 		JBrowse link
G Mir363 microRNA 363 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619438|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr  X:132,421,791...132,421,877
Ensembl chr  X:132,421,791...132,421,877 		JBrowse link
G Mir92a1 microRNA 92a-1 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676872|MGI:3618743|MGI:3619065|MGI:3629917 (PMID:18329372) RGD PMID:18329372 NCBI chr15:92,181,336...92,181,413
Ensembl chr15:92,181,336...92,181,413 		JBrowse link
G Mir92a2 microRNA 92a-2 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619439|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr  X:132,421,942...132,422,033
Ensembl chr  X:132,421,942...132,422,033 		JBrowse link
G Mir93 microRNA 93 acts_upstream_of_or_within ISO MGI:2676844|MGI:2676868|MGI:2676872|MGI:3618743|MGI:3618748|MGI:3619060|MGI:3619065|MGI:3619120|MGI:3619266|MGI:3619370|MGI:3619438|MGI:3629917|MGI:3629918|MGI:3718454 (PMID:18329372) RGD PMID:18329372 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO (PMID:20959462) RGD PMID:20959462 NCBI chr 5:166,820,150...166,831,949
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:6369059 (PMID:28747345)		 Ensembl
RGD		 PMID:28747345 GO_REF:0000107 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Pdcd1 programmed cell death 1 acts_upstream_of_or_within ISO (PMID:23636058) RGD PMID:23636058 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO MGI:5642301 (PMID:25074913) RGD PMID:25074913 NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325 		JBrowse link
negative regulation of mature B cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964)		 Ensembl
RGD		 PMID:14607964 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISO
ISS		 (PMID:15878976)
GO_REF:0000024		 RGD
UniProt		 PMID:15878976 GO_REF:0000024 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Cd44 CD44 molecule involved_in ISO (MGI:3773489|PMID:18056708) RGD PMID:18056708 MGI:3773489 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:3773489|PMID:18056708)		 BHF-UCL
RGD		 PMID:18056708 GO_REF:0000024 MGI:3773489 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:3773489|PMID:18056708) RGD PMID:18056708 MGI:3773489 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
negative regulation of T cell apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO MGI:2663971 (PMID:12717433) RGD PMID:12717433 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:7751019)		 Ensembl
RGD		 PMID:7751019 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO MGI:1197519 (PMID:16832056) RGD PMID:16832056 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO (PMID:10488085) RGD PMID:10488085 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Cd27 CD27 molecule acts_upstream_of_or_within ISO UniProtKB:P39429 (PMID:9692890) RGD PMID:9692890 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Dock8 dedicator of cytokinesis 8 acts_upstream_of_or_within ISO MGI:3835422 (PMID:21969276) RGD PMID:21969276 NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3505776 (PMID:18077788)		 Ensembl
RGD		 PMID:18077788 GO_REF:0000107 NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:9215624) RGD PMID:9215624 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Pip prolactin induced protein involved_in ISO (PMID:10072505) RGD PMID:10072505 NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921 		JBrowse link
G Prkcq protein kinase C, theta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:11342610), (PMID:16709830)		 UniProt
Ensembl
RGD		 PMID:11342610 PMID:16709830 GO_REF:0000024 GO_REF:0000107 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Rag1 recombination activating 1 acts_upstream_of_or_within ISO MGI:1353616 (PMID:18684012) RGD PMID:18684012 NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Serpinb9 serpin family B member 9 acts_upstream_of_or_within ISO MGI:3687210 (PMID:16618603) RGD PMID:16618603 NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230 		JBrowse link
G Slc46a2 solute carrier family 46, member 2 acts_upstream_of_or_within ISO MGI:97848 (PMID:18684012) RGD PMID:18684012 NCBI chr 5:74,800,226...74,808,128
Ensembl chr 5:74,800,226...74,808,128 		JBrowse link
negative regulation of thymocyte apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11067867), (PMID:16670300)		 Ensembl
RGD		 PMID:11067867 PMID:16670300 GO_REF:0000107 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO MGI:2663971 (PMID:16670294) RGD PMID:16670294 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2386448|MGI:3663359|MGI:98834 (PMID:11046052) RGD PMID:11046052 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12421925)		 Ensembl
UniProt
RGD		 PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Efna1 ephrin A1 acts_upstream_of_or_within ISO (PMID:16547242) RGD PMID:16547242 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2386679|MGI:2448686 (PMID:15456877)		 Ensembl
RGD		 PMID:15456877 GO_REF:0000107 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3619195|PMID:9973401)		 BHF-UCL
RGD		 PMID:9973401 GO_REF:0000024 MGI:3619195 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Kifap3 kinesin-associated protein 3 acts_upstream_of_or_within ISO MGI:3613572 (PMID:10793158) RGD PMID:10793158 NCBI chr13:76,127,702...76,264,654
Ensembl chr13:76,127,696...76,264,650 		JBrowse link
G Ptcra pre T-cell antigen receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000118
(PMID:15728238)
GO_REF:0000033		 TreeGrafter
RGD
GO_Central		 PMID:15728238 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:14,218,907...14,229,141
Ensembl chr 9:14,218,802...14,229,235 		JBrowse link
G Rag1 recombination activating 1 acts_upstream_of_or_within ISO (PMID:15728238) RGD PMID:15728238 NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Rorc RAR-related orphan receptor C involved_in ISO (MGI:3694879|PMID:16148126) RGD PMID:16148126 MGI:3694879 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO MGI:2136645|MGI:2448686 (PMID:15456877) RGD PMID:15456877 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    negative regulation of biological process 5812
      negative regulation of cellular process 5413
        negative regulation of programmed cell death 1099
          negative regulation of apoptotic process 1059
            negative regulation of leukocyte apoptotic process 75
              negative regulation of lymphocyte apoptotic process 54
                negative regulation of B cell apoptotic process + 26
                negative regulation of T cell apoptotic process + 29
                negative regulation of natural killer cell apoptotic process 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cell death 2208
        programmed cell death 2208
          apoptotic process 2126
            leukocyte apoptotic process 153
              lymphocyte apoptotic process 112
                regulation of lymphocyte apoptotic process 84
                  negative regulation of lymphocyte apoptotic process 54
                    negative regulation of B cell apoptotic process + 26
                    negative regulation of T cell apoptotic process + 29
                    negative regulation of natural killer cell apoptotic process 0
paths to the root