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Term:chemokine-mediated signaling pathway
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Accession:GO:0070098 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: chemokine-mediated signalling pathway

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chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccbp2 chemokine binding protein 2 GBrowse link IEA 9 121,807,582 121,820,182 RGD:2290270 GOC
G Ccbp2 chemokine binding protein 2 GBrowse link IDA 9 121,807,582 121,820,182 RGD:2290270 GOC
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link ISO 11 81,849,079 81,850,954 RGD:2290270 RGD
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link ISO 9 123,876,959 123,883,525 RGD:2290270 MGI
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link IDA 9 123,876,959 123,883,525 RGD:2290270 GOC
G Ccr10 chemokine (C-C motif) receptor 10 IDA RGD:2290270 GOC
G Ccr10 chemokine (C-C motif) receptor 10 GBrowse link IDA 11 101,034,312 101,036,757 RGD:2290270 GOC
G Ccr10 chemokine (C-C motif) receptor 10 IDA RGD:2290270 GOC
G Ccr10 chemokine (C-C motif) receptor 10 GBrowse link IDA 11 101,034,312 101,036,757 RGD:2290270 GOC
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 GBrowse link IEA 9 123,891,782 123,893,241 RGD:2290270 GOC
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link IEA 9 124,016,922 124,023,879 RGD:2290270 GOC
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link IDA 9 124,016,922 124,023,879 RGD:2290270 GOC
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link IDA 9 124,016,922 124,023,879 RGD:2290270 GOC
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link ISO 9 124,016,922 124,023,879 RGD:2290270 RGD
G Ccr3 chemokine (C-C motif) receptor 3 GBrowse link IEA 9 123,936,703 123,946,421 RGD:2290270 GOC
G Ccr3 chemokine (C-C motif) receptor 3 GBrowse link IDA 9 123,936,703 123,946,421 RGD:2290270 GOC
G Ccr4 chemokine (C-C motif) receptor 4 GBrowse link IEA 9 114,399,434 114,405,662 RGD:2290270 GOC
G Ccr4 chemokine (C-C motif) receptor 4 GBrowse link IMP 9 114,399,434 114,405,662 RGD:2290270 GOC
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link ISO 9 124,036,282 124,041,922 RGD:2290270 GOC
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link IEA 9 124,036,282 124,041,922 RGD:2290270 GOC
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link ISO 9 124,036,282 124,041,922 RGD:2290270 GOC
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link IDA 9 124,036,282 124,041,922 RGD:2290270 GOC
G Ccr6 chemokine (C-C motif) receptor 6 GBrowse link IEA 17 8,428,908 8,450,006 RGD:2290270 GOC
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link IEA 11 99,005,513 99,016,391 RGD:2290270 GOC
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link IMP 11 99,005,513 99,016,391 RGD:2290270 GOC
G Ccr8 chemokine (C-C motif) receptor 8 GBrowse link IEA 9 120,001,251 120,004,024 RGD:2290270 GOC
G Ccr8 chemokine (C-C motif) receptor 8 GBrowse link IDA 9 120,001,251 120,004,024 RGD:2290270 GOC
G Ccr9 chemokine (C-C motif) receptor 9 GBrowse link IEA 9 123,676,329 123,692,575 RGD:2290270 GOC
G Ccr9 chemokine (C-C motif) receptor 9 GBrowse link IDA 9 123,676,329 123,692,575 RGD:2290270 GOC
G Ccrl1 chemokine (C-C motif) receptor-like 1 GBrowse link IEA 9 104,000,468 104,028,973 RGD:2290270 UniProtKB
G Ccrl2 chemokine (C-C motif) receptor-like 2 GBrowse link ISS 9 110,957,339 110,959,774 RGD:2290270 GOC
G Ccrl2 chemokine (C-C motif) receptor-like 2 GBrowse link IEA 9 110,957,339 110,959,774 RGD:2290270 GOC
G Cx3cr1 chemokine (C-X3-C) receptor 1 GBrowse link IEA 9 119,957,811 119,977,400 RGD:2290270 GOC
G Cx3cr1 chemokine (C-X3-C) receptor 1 GBrowse link ISO 9 119,957,811 119,977,400 RGD:2290270 GOC
G Cxcl13 chemokine (C-X-C motif) ligand 13 GBrowse link NAS 5 96,385,958 96,390,087 RGD:2290270 BHF-UCL
G Cxcr1 chemokine (C-X-C motif) receptor 1 GBrowse link ISO 1 74,238,359 74,241,205 RGD:2290270 GOC
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link TAS 1 74,200,568 74,207,820 RGD:2290270 GOC
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link ISO 1 74,200,568 74,207,820 RGD:2290270 GOC
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link TAS 1 74,200,568 74,207,820 RGD:2290270 GOC
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link IDA 1 74,200,568 74,207,820 RGD:2290270 GOC
G Cxcr3 chemokine (C-X-C motif) receptor 3 GBrowse link ISO X 98,926,875 98,929,486 RGD:2290270 RGD
G Cxcr4 chemokine (C-X-C motif) receptor 4 GBrowse link IEA 1 130,484,776 130,488,876 RGD:2290270 GOC
G Cxcr5 chemokine (C-X-C motif) receptor 5 GBrowse link IEA 9 44,319,870 44,334,504 RGD:2290270 GOC
G Cxcr6 chemokine (C-X-C motif) receptor 6 GBrowse link IEA 9 123,715,595 123,720,872 RGD:2290270 GOC
G Cxcr6 chemokine (C-X-C motif) receptor 6 GBrowse link IDA 9 123,715,595 123,720,872 RGD:2290270 GOC
G Cxcr7 chemokine (C-X-C motif) receptor 7 GBrowse link ISO 1 92,100,578 92,112,863 RGD:2290270 MGI
G Ptk2b PTK2 protein tyrosine kinase 2 beta GBrowse link IMP 14 66,772,094 66,899,889 RGD:2290270 UniProtKB
G Tff2 trefoil factor 2 (spasmolytic protein 1) GBrowse link IGI 17 31,278,007 31,281,227 RGD:2290270 MGI
G Xcr1 chemokine (C motif) receptor 1 GBrowse link IEA 9 123,761,436 123,771,246 RGD:2290270 GOC
chemokine (C-C motif) ligand 19 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link ISO 11 99,005,513 99,016,391 RGD:2290270 MGI
chemokine (C-C motif) ligand 21 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link ISO 11 99,005,513 99,016,391 RGD:2290270 MGI
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link ISO 11 83,339,280 83,344,020 RGD:2290270 MGI
G Robo1 roundabout homolog 1 (Drosophila) GBrowse link ISO 16 72,663,394 73,046,345 RGD:2290270 MGI
G Slit2 slit homolog 2 (Drosophila) GBrowse link ISO 5 48,374,394 48,697,017 RGD:2290270 MGI
G Slit3 slit homolog 3 (Drosophila) GBrowse link ISO 11 34,934,958 35,522,009 RGD:2290270 MGI
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 124388
    single-organism process 70768
      single organism signaling 15769
        signal transduction 13928
          cell surface receptor signaling pathway 7411
            cytokine-mediated signaling pathway 321
              chemokine-mediated signaling pathway 55
                C-C chemokine receptor CCR2 signaling pathway + 0
                C-C chemokine receptor CCR4 signaling pathway + 0
                C-C chemokine receptor CCR7 signaling pathway + 0
                C-X-C chemokine receptor CXCR4 signaling pathway + 0
                chemokine (C-C motif) ligand 19 signaling pathway + 1
                chemokine (C-C motif) ligand 2 signaling pathway + 0
                chemokine (C-C motif) ligand 21 signaling pathway + 1
                chemokine (C-C motif) ligand 5 signaling pathway 0
                chemokine (C-X-C motif) ligand 12 signaling pathway + 0
                negative regulation of chemokine-mediated signaling pathway 4
                positive regulation of chemokine-mediated signaling pathway 0
                regulation of chemokine-mediated signaling pathway + 4
                thrombopoietin-mediated signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 124388
    cellular process 72448
      single-organism cellular process 46349
        cellular response to stimulus 17325
          cellular response to chemical stimulus 2674
            cellular response to organic substance 2005
              cellular response to cytokine stimulus 472
                cytokine-mediated signaling pathway 321
                  chemokine-mediated signaling pathway 55
                    C-C chemokine receptor CCR2 signaling pathway + 0
                    C-C chemokine receptor CCR4 signaling pathway + 0
                    C-C chemokine receptor CCR7 signaling pathway + 0
                    C-X-C chemokine receptor CXCR4 signaling pathway + 0
                    chemokine (C-C motif) ligand 19 signaling pathway + 1
                    chemokine (C-C motif) ligand 2 signaling pathway + 0
                    chemokine (C-C motif) ligand 21 signaling pathway + 1
                    chemokine (C-C motif) ligand 5 signaling pathway 0
                    chemokine (C-X-C motif) ligand 12 signaling pathway + 0
                    negative regulation of chemokine-mediated signaling pathway 4
                    positive regulation of chemokine-mediated signaling pathway 0
                    regulation of chemokine-mediated signaling pathway + 4
                    thrombopoietin-mediated signaling pathway 0
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