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Term:chemokine-mediated signaling pathway
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Accession:GO:0070098 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: chemokine-mediated signalling pathway

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chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccbp2 chemokine binding protein 2 GBrowse link ISO 8 127,026,528 127,028,214 RGD:1624291 RGD
G Ccl2 chemokine (C-C motif) ligand 2 GBrowse link IMP 10 70,256,263 70,258,061 RGD:2303073 RGD
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link ISO 8 128,693,658 128,699,213 RGD:1624291 RGD
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link ISO 8 128,693,658 128,699,213 RGD:1624291 RGD
G Ccr10 chemokine (C-C motif) receptor 10 GBrowse link ISO 10 90,193,776 90,196,213 RGD:1624291 RGD
G Ccr10 chemokine (C-C motif) receptor 10 GBrowse link ISO 10 90,193,776 90,196,213 RGD:1624291 RGD
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link IMP 8 128,892,784 128,893,905 RGD:2303073 RGD
G Ccr3 chemokine (C-C motif) receptor 3 GBrowse link TAS 8 128,759,943 128,769,341 RGD:632389 GOC
G Ccr3 chemokine (C-C motif) receptor 3 GBrowse link ISO 8 128,759,943 128,769,341 RGD:1624291 RGD
G Ccr4 chemokine (C-C motif) receptor 4 GBrowse link ISO 8 118,883,148 118,884,230 RGD:1624291 RGD
G Ccr5 chemokine (C-C motif) receptor 5 GBrowse link ISO 8 128,907,157 128,912,272 RGD:1624291 RGD
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link ISO 10 87,925,093 87,936,325 RGD:1624291 RGD
G Ccr8 chemokine (C-C motif) receptor 8 GBrowse link ISO 8 125,075,457 125,076,518 RGD:1624291 RGD
G Ccr9 chemokine (C-C motif) receptor 9 GBrowse link ISO 8 128,527,943 128,541,982 RGD:1624291 RGD
G Cxcl12 chemokine (C-X-C motif) ligand 12 GBrowse link ISO 4 153,503,576 153,516,423 RGD:1624291 RGD
G Cxcl12 chemokine (C-X-C motif) ligand 12 GBrowse link IEA 4 153,503,576 153,516,423 RGD:1600115 ENSEMBL
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link ISO 9 73,470,943 73,477,315 RGD:1624291 RGD
G Cxcr3 chemokine (C-X-C motif) receptor 3 GBrowse link IDA X 89,794,276 89,796,927 RGD:632989 GOC
G Cxcr6 chemokine (C-X-C motif) receptor 6 GBrowse link ISO 8 128,569,564 128,570,619 RGD:1624291 RGD
G Cxcr7 chemokine (C-X-C motif) receptor 7 GBrowse link ISO 9 89,343,528 89,355,053 RGD:1624291 RGD
G Ptk2b protein tyrosine kinase 2 beta GBrowse link ISS 15 45,589,222 45,717,866 RGD:1600115 UniProtKB
G Ptk2b protein tyrosine kinase 2 beta GBrowse link ISO 15 45,589,222 45,717,866 RGD:1624291 RGD
G Tff2 trefoil factor 2 GBrowse link ISO 20 9,492,341 9,510,558 RGD:1624291 RGD
G Tff2 trefoil factor 2 GBrowse link IEA 20 9,492,341 9,510,558 RGD:1600115 ENSEMBL
chemokine (C-C motif) ligand 19 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link ISO 10 87,925,093 87,936,325 RGD:1624291 RGD
chemokine (C-C motif) ligand 21 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccr7 chemokine (C-C motif) receptor 7 GBrowse link ISO 10 87,925,093 87,936,325 RGD:1624291 RGD
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccl5 chemokine (C-C motif) ligand 5 GBrowse link ISO 10 71,605,791 71,610,330 RGD:1624291 RGD
G Robo1 roundabout, axon guidance receptor, homolog 1 (Drosophila) GBrowse link ISO 11 10,784,947 11,720,646 RGD:1624291 RGD
G Slit2 slit homolog 2 (Drosophila) GBrowse link ISO 14 67,546,283 67,891,840 RGD:1624291 RGD
G Slit3 slit homolog 3 (Drosophila) GBrowse link ISO 10 19,983,166 20,576,689 RGD:1624291 RGD
G Slit3 slit homolog 3 (Drosophila) GBrowse link IEA 10 19,983,166 20,576,689 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    single-organism process 88399
      single organism signaling 16192
        signal transduction 13563
          cell surface receptor signaling pathway 7212
            cytokine-mediated signaling pathway 400
              chemokine-mediated signaling pathway 31
                C-C chemokine receptor CCR2 signaling pathway + 0
                C-C chemokine receptor CCR4 signaling pathway + 0
                C-C chemokine receptor CCR7 signaling pathway + 0
                C-X-C chemokine receptor CXCR4 signaling pathway + 0
                chemokine (C-C motif) ligand 19 signaling pathway + 1
                chemokine (C-C motif) ligand 2 signaling pathway + 0
                chemokine (C-C motif) ligand 21 signaling pathway + 1
                chemokine (C-C motif) ligand 5 signaling pathway 0
                chemokine (C-X-C motif) ligand 12 signaling pathway + 0
                negative regulation of chemokine-mediated signaling pathway 5
                positive regulation of chemokine-mediated signaling pathway 0
                regulation of chemokine-mediated signaling pathway + 5
                thrombopoietin-mediated signaling pathway 0
Path 2
Term Annotations click to browse term
  biological_process 135967
    cellular process 85138
      single-organism cellular process 56334
        cellular response to stimulus 19015
          cellular response to chemical stimulus 4549
            cellular response to organic substance 3309
              cellular response to cytokine stimulus 741
                cytokine-mediated signaling pathway 400
                  chemokine-mediated signaling pathway 31
                    C-C chemokine receptor CCR2 signaling pathway + 0
                    C-C chemokine receptor CCR4 signaling pathway + 0
                    C-C chemokine receptor CCR7 signaling pathway + 0
                    C-X-C chemokine receptor CXCR4 signaling pathway + 0
                    chemokine (C-C motif) ligand 19 signaling pathway + 1
                    chemokine (C-C motif) ligand 2 signaling pathway + 0
                    chemokine (C-C motif) ligand 21 signaling pathway + 1
                    chemokine (C-C motif) ligand 5 signaling pathway 0
                    chemokine (C-X-C motif) ligand 12 signaling pathway + 0
                    negative regulation of chemokine-mediated signaling pathway 5
                    positive regulation of chemokine-mediated signaling pathway 0
                    regulation of chemokine-mediated signaling pathway + 5
                    thrombopoietin-mediated signaling pathway 0
paths to the root

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