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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of dendritic spine morphogenesis
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Accession:GO:0061002 term browser browse the term
Definition:Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.


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negative regulation of dendritic spine morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnm3 dynamin 3 IDA RGD PMID:17880892 RGD:8553820 NCBI chr13:74,359,043...74,838,135
Ensembl chr13:74,359,213...74,838,108 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 IMP
IDA		 RGD PMID:20531346 PMID:20531346 RGD:11251757, RGD:11251757 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Efna1 ephrin A1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3696283|PMID:17143272)		 UniProt
RGD		 PMID:17143272 GO_REF:0000024 MGI:3696283 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISS
ISO		 GO_REF:0000024
(MGI:3696283|PMID:17143272)		 UniProt
RGD		 PMID:17143272 GO_REF:0000024 MGI:3696283 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914 		JBrowse link
G Nlgn1 neuroligin 1 involved_in ISO
ISS
IEA		 UniProtKB:Q99K10 (PMID:23143522)
GO_REF:0000024
(MGI:5493186|PMID:23143522)
GO_REF:0000107		 RGD
BHF-UCL
Ensembl		 PMID:23143522 GO_REF:0000024 GO_REF:0000107 MGI:5493186 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464 		JBrowse link
G Nlgn3 neuroligin 3 involved_in ISO (MGI:5286761|PMID:21808020) RGD PMID:21808020 MGI:5286761 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (MGI:3629385|PMID:16675393) RGD PMID:16675393 MGI:3629385 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ube3a ubiquitin protein ligase E3A IMP RGD PMID:25867122 RGD:11079590 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    developmental process 7042
      negative regulation of developmental process 1104
        negative regulation of dendritic spine development 17
          negative regulation of dendritic spine morphogenesis 8
Path 2
Term Annotations click to browse term
  biological_process 20292
    developmental process 7042
      anatomical structure development 6550
        multicellular organism development 5276
          system development 4559
            nervous system development 2819
              neurogenesis 2091
                generation of neurons 1803
                  neuron differentiation 1721
                    neuron development 1419
                      neuron projection development 1245
                        dendrite development 329
                          dendritic spine development 133
                            regulation of dendritic spine development 85
                              negative regulation of dendritic spine development 17
                                negative regulation of dendritic spine morphogenesis 8
paths to the root