ONTOLOGY REPORT - ANNOTATIONS

Term:interferon-gamma-mediated signaling pathway
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Accession:GO:0060333 term browser browse the term
Definition:A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: immune interferon signaling pathway;   interferon-gamma-mediated signalling pathway;   type II interferon-mediated signaling pathway
 related_synonym: type II IFN-mediated signaling pathway
 xref_analog: Reactome:REACT_25078

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interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Irf1 interferon regulatory factor 1 GBrowse link ISO 10 39,220,600 39,227,602 RGD:1624291 RGD
G Irf1 interferon regulatory factor 1 GBrowse link ISS 10 39,220,600 39,227,602 RGD:1600115 UniProtKB
G Irf1 interferon regulatory factor 1 GBrowse link IEA 10 39,220,600 39,227,602 RGD:1600115 ENSEMBL
G Jak2 Janus kinase 2 GBrowse link IDA 1 232,915,995 232,974,763 BHF-UCL
G Stat1 signal transducer and activator of transcription 1 GBrowse link ISO 9 46,455,635 46,497,560 RGD:1624291 RGD
G Stat1 signal transducer and activator of transcription 1 GBrowse link IEA 9 46,455,635 46,497,560 RGD:1600115 ENSEMBL
negative regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link ISO 10 10,984,721 11,009,374 RGD:1624291 RGD
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link IEA 10 10,984,721 11,009,374 RGD:1600115 ENSEMBL
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link ISO 4 151,492,220 151,617,331 RGD:1624291 RGD
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link IEA 4 151,492,220 151,617,331 RGD:1600115 ENSEMBL
positive regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hpx hemopexin GBrowse link ISO 1 163,319,509 163,327,017 RGD:1624291 RGD
G Hpx hemopexin GBrowse link IEA 1 163,319,509 163,327,017 RGD:1600115 ENSEMBL
G Med1 mediator complex subunit 1 GBrowse link ISO 10 86,917,525 86,959,080 RGD:1624291 RGD
G Med1 mediator complex subunit 1 GBrowse link IEA 10 86,917,525 86,959,080 RGD:1600115 ENSEMBL
G Txk TXK tyrosine kinase GBrowse link ISO 14 37,867,565 37,923,075 RGD:1624291 RGD
G Txk TXK tyrosine kinase GBrowse link IEA 14 37,867,565 37,923,075 RGD:1600115 ENSEMBL
regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cdc37 cell division cycle 37 GBrowse link ISO 8 20,164,150 20,176,763 RGD:1624291 RGD
G Cdc37 cell division cycle 37 GBrowse link IEA 8 20,164,150 20,176,763 RGD:1600115 ENSEMBL
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 GBrowse link ISO 9 11,033,496 11,038,868 RGD:1624291 RGD
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 GBrowse link IEA 9 11,033,496 11,038,868 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    regulation of biological process 51470
      regulation of cellular process 43219
        signal transduction 13563
          cell surface receptor signaling pathway 7212
            cytokine-mediated signaling pathway 400
              interferon-gamma-mediated signaling pathway 20
                negative regulation of interferon-gamma-mediated signaling pathway 4
                positive regulation of interferon-gamma-mediated signaling pathway 6
                regulation of interferon-gamma-mediated signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 135967
    single-organism process 88399
      single-organism cellular process 56334
        cellular response to stimulus 19015
          cellular response to chemical stimulus 4549
            cellular response to organic substance 3309
              cellular response to cytokine stimulus 741
                cytokine-mediated signaling pathway 400
                  interferon-gamma-mediated signaling pathway 20
                    negative regulation of interferon-gamma-mediated signaling pathway 4
                    positive regulation of interferon-gamma-mediated signaling pathway 6
                    regulation of interferon-gamma-mediated signaling pathway + 14
paths to the root

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