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ONTOLOGY REPORT - ANNOTATIONS


Term:proton-transporting ATP synthase activity, rotational mechanism
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Accession:GO:0046933 term browser browse the term
Definition:Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).
Synonyms:exact_synonym: hydrogen ion transporting ATP synthase activity, rotational mechanism
 related_synonym: H+-transporting ATP synthase activity
 xref: EC:7.1.2.2;   MetaCyc:ATPSYN-RXN;   RHEA:57720;   TC:3.A.2.1.1;   reactome:R-HSA-164832 "ATPase synthesizes ATP"



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proton-transporting ATP synthase activity, rotational mechanism term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025819.1 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr16:48,628,407...48,628,892 JBrowse link
G AC105662.3 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 6:98,696,037...98,697,181 JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha contributes_to
enables
ISO
IEA
IBA
(PMID:12110673)
(PMID:21106936)
GO_REF:0000107
GO_REF:0000002
GO_REF:0000118
GO_REF:0000033
(PMID:17612527)
RGD
Ensembl
InterPro
TreeGrafter
GO_Central
PMID:12110673 PMID:17612527 PMID:21106936 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta contributes_to
enables
ISO
IEA
ISS
IBA
(PMID:12110673)
GO_REF:0000003
GO_REF:0000024
(PMID:21106936), (PMID:36239646)
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:12110673 PMID:21106936 PMID:36239646 GO_REF:0000003 GO_REF:0000024 GO_REF:0000033 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma enables
contributes_to
IEA
ISO
IBA
GO_REF:0000002
(PMID:12110673)
GO_REF:0000118
GO_REF:0000033
InterPro
RGD
TreeGrafter
GO_Central
PMID:12110673 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367
JBrowse link
G Atp5f1d ATP synthase F1 subunit delta contributes_to
enables
TAS
ISO
IEA
IBA
(PMID:12110673)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
RGD
InterPro
Ensembl
GO_Central
TreeGrafter
PMID:12110673 PMID:9578578 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:724594 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon contributes_to
enables
ISO
IEA
IBA
(PMID:12110673)
GO_REF:0000002
GO_REF:0000033
GO_REF:0000118
RGD
InterPro
GO_Central
TreeGrafter
PMID:12110673 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp5hl1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d-like 1 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr16:48,628,349...48,628,948
Ensembl chr16:48,628,407...48,628,892
JBrowse link
G Atp5me ATP synthase membrane subunit e contributes_to ISO (PMID:12110673) RGD PMID:12110673 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp5mf ATP synthase membrane subunit f contributes_to
enables
ISO
IEA
IBA
(PMID:12110673)
GO_REF:0000118
GO_REF:0000033
RGD
TreeGrafter
GO_Central
PMID:12110673 GO_REF:0000033 GO_REF:0000118 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
JBrowse link
G Atp5mg ATP synthase membrane subunit G contributes_to
enables
ISO
IBA
IEA
(PMID:12110673)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:12110673 GO_REF:0000033 GO_REF:0000118 NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559
JBrowse link
G Atp5mgl3 ATP synthase membrane subunit G like 3 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 6:15,945,315...15,945,626
Ensembl chr 6:15,945,315...15,945,626
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b contributes_to
enables
ISO
IEA
IBA
(PMID:12110673)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
RGD
Ensembl
GO_Central
TreeGrafter
PMID:12110673 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d contributes_to
enables
ISO
IBA
IEA
(PMID:12110673)
GO_REF:0000033
GO_REF:0000118
RGD
GO_Central
TreeGrafter
PMID:12110673 GO_REF:0000033 GO_REF:0000118 NCBI chr10:100,657,700...100,662,960
Ensembl chr10:100,657,708...100,663,479
JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 contributes_to ISO (PMID:12110673) RGD PMID:12110673 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP contributes_to
enables
ISO
IEA
IBA
(PMID:12110673)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:12110673 GO_REF:0000033 GO_REF:0000107 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A enables IEA GO_REF:0000003 UniProt GO_REF:0000003 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G LOC100361879 ATP synthase subunit epsilon, mitochondrial-like contributes_to IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:77,863,480...77,864,135
Ensembl chr14:77,863,571...77,863,729
JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 contributes_to ISO
IBA
(PMID:12110673)
GO_REF:0000033
RGD
GO_Central
PMID:12110673 GO_REF:0000033 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599
JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 contributes_to ISO (PMID:12110673) RGD PMID:12110673 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961
JBrowse link
G Taf3 TATA-box binding protein associated factor 3 enables IEA GO_REF:0000002
GO_REF:0000118
InterPro
TreeGrafter
GO_REF:0000002 GO_REF:0000118 NCBI chr17:68,455,389...68,608,367
Ensembl chr17:68,423,909...68,608,367
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    catalytic activity 6118
      ligase activity 180
        proton-transporting ATP synthase activity, rotational mechanism 21
Path 2
Term Annotations click to browse term
  molecular_function 20890
    transporter activity 1252
      transmembrane transporter activity 1157
        passive transmembrane transporter activity 517
          channel activity 517
            monoatomic ion channel activity 456
              monoatomic cation channel activity 345
                proton channel activity 29
                  proton-transporting ATP synthase activity, rotational mechanism 21
paths to the root