ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of hormone secretion
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Accession:GO:0046888 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
Synonyms:exact_synonym: down regulation of hormone secretion;   downregulation of hormone secretion
 narrow_synonym: inhibition of hormone secretion


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negative regulation of hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link 11 79,908,291 79,911,065 RGD:1599138
G Adora1 adenosine A1 receptor GBrowse link 13 47,160,292 47,192,804 RGD:1625242
G Edn1 endothelin 1 GBrowse link 17 28,303,886 28,309,775 RGD:1581817
G Edn2 endothelin 2 GBrowse link 5 140,742,686 140,747,580 RGD:1581817
G Edn3 endothelin 3 GBrowse link 3 166,491,368 166,514,051 RGD:1581817
G Fgf23 fibroblast growth factor 23 GBrowse link 4 163,468,604 163,476,325 RGD:8554413
G Il11 interleukin 11 GBrowse link 1 67,784,584 67,795,141 RGD:1600115
RGD:1624291
G Il6 interleukin 6 GBrowse link 4 456,799 461,376 RGD:1600115
RGD:1624291
G Lif leukemia inhibitory factor GBrowse link 14 84,887,856 84,890,630 RGD:1600115
RGD:1624291
G Nmb neuromedin B GBrowse link 1 137,097,463 137,100,207 RGD:1642347
G Npy1r neuropeptide Y receptor Y1 GBrowse link 16 24,747,183 24,756,507 RGD:1642321
G Osm oncostatin M GBrowse link 14 84,857,232 84,860,082 RGD:1600115
RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1624291
G Ucn urocortin GBrowse link 6 25,216,788 25,217,618 RGD:5490560
negative regulation of adiponectin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1600115
RGD:1624291
negative regulation of corticotropin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crhbp corticotropin releasing hormone binding protein GBrowse link 2 25,801,371 25,813,457 RGD:69816
RGD:1600115
RGD:1624291
negative regulation of cortisol secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1600115
RGD:1624291
negative regulation of epinephrine secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone GBrowse link 2 104,764,023 104,765,887 RGD:704397
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link 10 93,312,405 93,354,229 RGD:704397
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 83,839,822 83,867,017 RGD:5131263
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 GBrowse link 20 1,553,297 1,582,426 RGD:2315495
G Gck glucokinase GBrowse link 14 86,572,518 86,587,723 RGD:2301900
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link 3 15,343,832 15,365,412 RGD:2300224
negative regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 83,839,822 83,867,017 RGD:2317015
G Fst follistatin GBrowse link 2 46,542,246 46,550,678 RGD:69839
G Inha inhibin alpha GBrowse link 9 74,781,223 74,784,124 RGD:2290442
RGD:2290444
G Inhbb inhibin beta-B GBrowse link 13 32,170,987 32,176,689 RGD:1600115
RGD:1624291
G Ucn2 urocortin 2 GBrowse link 8 114,003,817 114,005,366 RGD:2317015
negative regulation of glucagon secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cartpt CART prepropeptide GBrowse link 2 30,889,817 30,891,837 RGD:2313632
G Crh corticotropin releasing hormone GBrowse link 2 104,764,023 104,765,887 RGD:704397
G Lep leptin GBrowse link 4 55,943,837 55,945,938 RGD:1600115
RGD:1624291
negative regulation of glucocorticoid secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cry1 cryptochrome circadian clock 1 GBrowse link 7 20,643,879 20,709,216 RGD:1600115
RGD:1624291
G Cry2 cryptochrome circadian clock 2 GBrowse link 3 76,802,782 76,830,902 RGD:1600115
RGD:1624291
negative regulation of gonadotropin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Npvf neuropeptide VF precursor GBrowse link 4 78,886,521 78,890,237 RGD:1624291
negative regulation of growth hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 GBrowse link 20 25,675,302 25,686,494 RGD:9585999
negative regulation of insulin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link 1 96,622,574 96,703,723 RGD:1598646
G Acvr1c activin A receptor, type IC GBrowse link 3 40,027,228 40,102,303 RGD:1600115
RGD:1624291
G Adra2a adrenoceptor alpha 2A RGD:1624291
G Bmp8a bone morphogenetic protein 8a GBrowse link 5 142,627,733 142,653,782 RGD:1624291
G Drd2 dopamine receptor D2 GBrowse link 8 52,641,160 52,707,749 RGD:2311570
G Fam3d family with sequence similarity 3, member D GBrowse link 15 18,520,414 18,554,410 RGD:1600115
RGD:1624291
G Ghrl ghrelin/obestatin prepropeptide GBrowse link 4 149,622,566 149,628,111 RGD:1624291
RGD:8553721
G Ghsr growth hormone secretagogue receptor GBrowse link 2 113,269,623 113,272,999 RGD:8553721
G Hadh hydroxyacyl-CoA dehydrogenase GBrowse link 2 228,698,545 228,751,691 RGD:2302227
G Inhbb inhibin beta-B GBrowse link 13 32,170,987 32,176,689 RGD:1600115
RGD:1624291
G Irs1 insulin receptor substrate 1 GBrowse link 9 81,585,251 81,638,071 RGD:729325
RGD:1600115
RGD:1624291
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link 1 96,614,960 96,617,993 RGD:1600115
RGD:1624291
G Kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 GBrowse link 1 203,383,401 203,803,687 RGD:1581603
G Midn midnolin GBrowse link 7 11,061,651 11,068,365 RGD:8655525
G Nos1 nitric oxide synthase 1, neuronal GBrowse link 12 39,812,500 39,869,484 RGD:1642149
G Npff neuropeptide FF-amide peptide precursor RGD:2316580
G Park2 parkinson protein 2, E3 ubiquitin protein ligase GBrowse link 1 43,151,265 44,374,470 RGD:1600115
RGD:1624291
G Pde1c phosphodiesterase 1C GBrowse link 4 84,936,642 85,448,339 RGD:2302857
G Pde3b phosphodiesterase 3B, cGMP-inhibited GBrowse link 1 172,409,282 172,577,108 RGD:2302857
G Pde4c phosphodiesterase 4C, cAMP-specific GBrowse link 16 19,197,277 19,215,627 RGD:2302857
G Pde8b phosphodiesterase 8B GBrowse link 2 25,352,725 25,469,209 RGD:2302857
RGD:2312519
G Pfkl phosphofructokinase, liver GBrowse link 20 11,009,359 11,032,511 RGD:1600115
RGD:1624291
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme GBrowse link 2 234,130,176 234,409,232 RGD:2316628
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 GBrowse link 12 34,472,250 34,500,731 RGD:8554418
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1600115
RGD:1624291
G Rest RE1-silencing transcription factor GBrowse link 14 33,136,046 33,151,142 RGD:1600115
RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 GBrowse link 16 73,030,458 73,067,304 RGD:1600115
RGD:1624291
G Sirt4 sirtuin 4 GBrowse link 12 42,394,536 42,402,714 RGD:1600115
RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link 10 46,461,684 46,483,646 RGD:1600115
RGD:1624291
G Stxbp5l syntaxin binding protein 5-like GBrowse link 11 65,129,572 65,455,115 RGD:1600115
RGD:1624291
G Sytl4 synaptotagmin-like 4 GBrowse link X 121,473,414 121,499,134 RGD:1600115
RGD:1624291
G Uts2 urotensin 2 GBrowse link 5 168,143,315 168,148,700 RGD:2306798
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A RGD:1600115
RGD:1624291
RGD:2316628
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 83,839,822 83,867,017 RGD:2306172
G Fkbp1b FK506 binding protein 1B RGD:1600115
RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link 2 27,127,504 27,149,580 RGD:5508687
G LOC259246 alpha-2u globulin PGCL1 GBrowse link 5 78,707,324 78,710,745 RGD:1600115
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 GBrowse link 9 39,087,924 39,213,053 RGD:7495848
G Ndufaf2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 GBrowse link 2 39,269,415 39,382,833 RGD:1624291
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase GBrowse link 7 127,167,984 127,172,018 RGD:1600115
RGD:1624291
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link 1 157,925,514 157,928,222 RGD:7204422
negative regulation of luteinizing hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone GBrowse link 2 104,764,023 104,765,887 RGD:5508201
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 83,839,822 83,867,017 RGD:2317015
G Tacr2 tachykinin receptor 2 RGD:5147487
G Ucn2 urocortin 2 GBrowse link 8 114,003,817 114,005,366 RGD:2317015
negative regulation of peptide hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link 4 151,492,220 151,617,331 RGD:1624291
negative regulation of somatostatin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Irs1 insulin receptor substrate 1 GBrowse link 9 81,585,251 81,638,071 RGD:729325

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 454737
    negative regulation of biological process 41544
      negative regulation of signaling 6401
        negative regulation of hormone secretion 278
          negative regulation of activin secretion 0
          negative regulation of adiponectin secretion 5
          negative regulation of corticotropin-releasing hormone secretion 0
          negative regulation of epinephrine secretion 18
          negative regulation of gonadotropin secretion + 29
          negative regulation of inhibin secretion 0
          negative regulation of juvenile hormone secretion 0
          negative regulation of parathyroid hormone secretion 0
          negative regulation of peptide hormone secretion + 172
          negative regulation of steroid hormone secretion + 12
Path 2
Term Annotations click to browse term
  biological_process 454737
    localization 50475
      establishment of localization 39567
        transport 38758
          single-organism transport 30757
            secretion 5483
              secretion by cell 4647
                signal release 1909
                  hormone secretion 1417
                    regulation of hormone secretion 1087
                      negative regulation of hormone secretion 278
                        negative regulation of activin secretion 0
                        negative regulation of adiponectin secretion 5
                        negative regulation of corticotropin-releasing hormone secretion 0
                        negative regulation of epinephrine secretion 18
                        negative regulation of gonadotropin secretion + 29
                        negative regulation of inhibin secretion 0
                        negative regulation of juvenile hormone secretion 0
                        negative regulation of parathyroid hormone secretion 0
                        negative regulation of peptide hormone secretion + 172
                        negative regulation of steroid hormone secretion + 12
paths to the root