ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of hormone secretion
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Accession:GO:0046888 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
Synonyms:exact_synonym: down regulation of hormone secretion;   downregulation of hormone secretion
 narrow_synonym: inhibition of hormone secretion


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negative regulation of hormone secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link IDA 11 79,908,291 79,911,065 RGD:1599138 RGD
G Adora1 adenosine A1 receptor GBrowse link IMP 13 47,160,292 47,192,804 RGD:1625242 RGD
G Edn1 endothelin 1 GBrowse link IDA 17 28,303,886 28,309,775 RGD:1581817 RGD
G Edn2 endothelin 2 GBrowse link IDA 5 140,742,686 140,747,580 RGD:1581817 RGD
G Edn3 endothelin 3 GBrowse link IDA 3 166,491,368 166,514,051 RGD:1581817 RGD
G Fgf23 fibroblast growth factor 23 GBrowse link IDA 4 163,468,604 163,476,325 UniProt
G Il11 interleukin 11 GBrowse link IEA 1 67,784,584 67,795,141 RGD:1600115 Ensembl
G Il11 interleukin 11 GBrowse link ISO 1 67,784,584 67,795,141 RGD:1624291 RGD
G Il6 interleukin 6 GBrowse link ISO 4 456,799 461,376 RGD:1624291 RGD
G Il6 interleukin 6 GBrowse link IEA 4 456,799 461,376 RGD:1600115 Ensembl
G Lif leukemia inhibitory factor GBrowse link IEA 14 84,887,856 84,890,630 RGD:1600115 Ensembl
G Lif leukemia inhibitory factor GBrowse link ISO 14 84,887,856 84,890,630 RGD:1624291 RGD
G Nmb neuromedin B GBrowse link IMP 1 137,097,463 137,100,207 RGD:1642347 RGD
G Npy1r neuropeptide Y receptor Y1 GBrowse link IMP 16 24,747,183 24,756,507 RGD:1642321 RGD
G Osm oncostatin M GBrowse link ISO 14 84,857,232 84,860,082 RGD:1624291 RGD
G Osm oncostatin M GBrowse link IEA 14 84,857,232 84,860,082 RGD:1600115 Ensembl
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISO 12 36,501,886 36,558,055 RGD:1624291 RGD
G Ucn urocortin GBrowse link IDA 6 25,216,788 25,217,618 RGD:5490560 RGD
negative regulation of adiponectin secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il1b interleukin 1 beta GBrowse link ISO 3 116,964,422 116,970,867 RGD:1624291 RGD
G Il1b interleukin 1 beta GBrowse link IEA 3 116,964,422 116,970,867 RGD:1600115 Ensembl
negative regulation of corticotropin secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Crhbp corticotropin releasing hormone binding protein GBrowse link ISO 2 25,801,371 25,813,457 RGD:1624291 RGD
G Crhbp corticotropin releasing hormone binding protein GBrowse link IEA 2 25,801,371 25,813,457 RGD:1600115 Ensembl
G Crhbp corticotropin releasing hormone binding protein GBrowse link IDA 2 25,801,371 25,813,457 RGD:69816 UniProt
negative regulation of cortisol secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISO 12 36,501,886 36,558,055 RGD:1624291 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IEA 12 36,501,886 36,558,055 RGD:1600115 Ensembl
negative regulation of epinephrine secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Crh corticotropin releasing hormone GBrowse link IDA 2 104,764,023 104,765,887 RGD:704397 RGD
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link IMP 10 93,312,405 93,354,229 RGD:704397 RGD
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link IMP 4 83,839,822 83,867,017 RGD:5131263 RGD
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 GBrowse link IMP 20 1,553,297 1,582,426 RGD:2315495 RGD
G Gck glucokinase GBrowse link IMP 14 86,572,518 86,587,723 RGD:2301900 RGD
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link IMP 3 15,343,832 15,365,412 RGD:2300224 RGD
negative regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link IMP 4 83,839,822 83,867,017 RGD:2317015 RGD
G Fst follistatin GBrowse link TAS 2 46,542,246 46,550,678 RGD:69839 RGD
G Inha inhibin alpha GBrowse link IMP 9 74,781,223 74,784,124 RGD:2290444 RGD
G Inha inhibin alpha GBrowse link IMP 9 74,781,223 74,784,124 RGD:2290442 RGD
G Inhbb inhibin beta-B GBrowse link ISO 13 32,170,987 32,176,689 RGD:1624291 RGD
G Inhbb inhibin beta-B GBrowse link ISS 13 32,170,987 32,176,689 RGD:1600115 UniProt
G Ucn2 urocortin 2 GBrowse link IMP 8 114,003,817 114,005,366 RGD:2317015 RGD
negative regulation of glucagon secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cartpt CART prepropeptide GBrowse link IDA 2 30,889,817 30,891,837 RGD:2313632 RGD
G Crh corticotropin releasing hormone GBrowse link IDA 2 104,764,023 104,765,887 RGD:704397 RGD
G Lep leptin GBrowse link ISO 4 55,943,837 55,945,938 RGD:1624291 RGD
G Lep leptin GBrowse link IEA 4 55,943,837 55,945,938 RGD:1600115 Ensembl
negative regulation of gonadotropin secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Npvf neuropeptide VF precursor GBrowse link ISO 4 78,886,521 78,890,237 RGD:1624291 RGD
negative regulation of growth hormone secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISO 12 36,501,886 36,558,055 RGD:1624291 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IEA 12 36,501,886 36,558,055 RGD:1600115 Ensembl
negative regulation of insulin secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link IDA 1 96,622,574 96,703,723 RGD:1598646 RGD
G Acvr1c activin A receptor, type IC GBrowse link ISO 3 40,027,228 40,102,303 RGD:1624291 RGD
G Acvr1c activin A receptor, type IC GBrowse link IEA 3 40,027,228 40,102,303 RGD:1600115 Ensembl
G Adra2a adrenoceptor alpha 2A ISO RGD:1624291 RGD
G Bmp8b bone morphogenetic protein 8b GBrowse link ISO 5 142,421,940 142,440,765 RGD:1624291 RGD
G Drd2 dopamine receptor D2 GBrowse link IMP 8 52,641,160 52,707,749 RGD:2311570 RGD
G Fam3d family with sequence similarity 3, member D GBrowse link IEA 15 18,520,414 18,554,410 RGD:1600115 Ensembl
G Fam3d family with sequence similarity 3, member D GBrowse link ISO 15 18,520,414 18,554,410 RGD:1624291 RGD
G Ghrl ghrelin/obestatin prepropeptide GBrowse link ISO 4 149,622,566 149,628,111 RGD:1624291 RGD
G Ghrl ghrelin/obestatin prepropeptide GBrowse link IDA 4 149,622,566 149,628,111 MGI
G Ghsr growth hormone secretagogue receptor GBrowse link IDA 2 113,269,623 113,272,999 MGI
G Hadh hydroxyacyl-CoA dehydrogenase GBrowse link IMP 2 228,698,545 228,751,691 RGD:2302227 RGD
G Inhbb inhibin beta-B GBrowse link ISO 13 32,170,987 32,176,689 RGD:1624291 RGD
G Inhbb inhibin beta-B GBrowse link ISS 13 32,170,987 32,176,689 RGD:1600115 UniProt
G Irs1 insulin receptor substrate 1 GBrowse link ISO 9 81,585,251 81,638,071 RGD:1624291 RGD
G Irs1 insulin receptor substrate 1 GBrowse link IEA 9 81,585,251 81,638,071 RGD:1600115 Ensembl
G Irs1 insulin receptor substrate 1 GBrowse link IMP 9 81,585,251 81,638,071 RGD:729325 BHF-UCL
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link ISO 1 96,614,960 96,617,993 RGD:1624291 RGD
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link IEA 1 96,614,960 96,617,993 RGD:1600115 Ensembl
G Kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 GBrowse link IDA 1 203,383,401 203,803,687 RGD:1581603 RGD
G Nos1 nitric oxide synthase 1, neuronal GBrowse link IMP 12 39,812,500 39,869,484 RGD:1642149 RGD
G Npff neuropeptide FF-amide peptide precursor IDA RGD:2316580 RGD
G Pde1c phosphodiesterase 1C GBrowse link IMP 4 84,936,642 85,448,339 RGD:2302857 RGD
G Pde3b phosphodiesterase 3B, cGMP-inhibited GBrowse link IMP 1 172,409,282 172,577,108 RGD:2302857 RGD
G Pde4c phosphodiesterase 4C, cAMP-specific GBrowse link IMP 16 19,197,277 19,215,627 RGD:2302857 RGD
G Pde8b phosphodiesterase 8B GBrowse link IMP 2 25,352,725 25,469,209 RGD:2312519 RGD
G Pde8b phosphodiesterase 8B GBrowse link IMP 2 25,352,725 25,469,209 RGD:2302857 RGD
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkl phosphofructokinase, liver GBrowse link IEA 20 11,009,359 11,032,511 RGD:1600115 Ensembl
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme GBrowse link IMP 2 234,130,176 234,409,232 RGD:2316628 BHF-UCL
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 GBrowse link IMP 12 34,472,250 34,500,731 BHF-UCL
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link ISO 12 36,501,886 36,558,055 RGD:1624291 RGD
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link IEA 12 36,501,886 36,558,055 RGD:1600115 Ensembl
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link ISO 13 48,070,488 48,090,682 RGD:1624291 RGD
G Rest RE1-silencing transcription factor GBrowse link ISO 14 33,136,046 33,151,142 RGD:1624291 RGD
G Rest RE1-silencing transcription factor GBrowse link ISS 14 33,136,046 33,151,142 RGD:1600115 UniProt
G Rest RE1-silencing transcription factor GBrowse link IEA 14 33,136,046 33,151,142 RGD:1600115 Ensembl
G Sfrp1 secreted frizzled-related protein 1 GBrowse link IEA 16 73,030,458 73,067,304 RGD:1600115 Ensembl
G Sfrp1 secreted frizzled-related protein 1 GBrowse link ISO 16 73,030,458 73,067,304 RGD:1624291 RGD
G Sirt4 sirtuin 4 GBrowse link ISO 12 42,394,536 42,402,714 RGD:1624291 RGD
G Sirt4 sirtuin 4 GBrowse link IEA 12 42,394,536 42,402,714 RGD:1600115 Ensembl
G Sirt4 sirtuin 4 GBrowse link ISO 12 42,394,536 42,402,714 RGD:1624291 RGD
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link ISO 10 46,461,684 46,483,646 RGD:1624291 RGD
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link IEA 10 46,461,684 46,483,646 RGD:1600115 Ensembl
G Stxbp5l syntaxin binding protein 5-like GBrowse link ISO 11 65,129,572 65,455,115 RGD:1624291 RGD
G Stxbp5l syntaxin binding protein 5-like GBrowse link IEA 11 65,129,572 65,455,115 RGD:1600115 Ensembl
G Sytl4 synaptotagmin-like 4 GBrowse link ISO X 121,473,414 121,499,134 RGD:1624291 RGD
G Sytl4 synaptotagmin-like 4 GBrowse link IEA X 121,473,414 121,499,134 RGD:1600115 Ensembl
G Uts2 urotensin 2 GBrowse link IMP 5 168,143,315 168,148,700 RGD:2306798 RGD
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adra2a adrenoceptor alpha 2A IMP RGD:2316628 BHF-UCL
G Adra2a adrenoceptor alpha 2A ISO RGD:1624291 RGD
G Adra2a adrenoceptor alpha 2A IEA RGD:1600115 Ensembl
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link IMP 4 83,839,822 83,867,017 RGD:2306172 RGD
G Fkbp1b FK506 binding protein 1B IEA RGD:1600115 Ensembl
G Fkbp1b FK506 binding protein 1B ISO RGD:1624291 RGD
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link IMP 2 27,127,504 27,149,580 RGD:5508687 RGD
G LOC259246 alpha-2u globulin PGCL1 GBrowse link ISS 5 78,707,324 78,710,745 RGD:1600115 UniProt
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 GBrowse link IMP 9 39,087,924 39,213,053 RGD:7495848 RGD
G Ndufaf2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 GBrowse link ISO 2 39,269,415 39,382,833 RGD:1624291 RGD
G Pim3 pim-3 oncogene GBrowse link ISO 7 127,167,984 127,172,018 RGD:1624291 RGD
G Pim3 pim-3 oncogene GBrowse link IEA 7 127,167,984 127,172,018 RGD:1600115 Ensembl
G Pim3 pim-3 oncogene GBrowse link ISS 7 127,167,984 127,172,018 RGD:1600115 UniProt
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link IMP 1 157,925,514 157,928,222 RGD:7204422 RGD
negative regulation of luteinizing hormone secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Crh corticotropin releasing hormone GBrowse link IMP 2 104,764,023 104,765,887 RGD:5508201 RGD
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link IMP 4 83,839,822 83,867,017 RGD:2317015 RGD
G Tacr2 tachykinin receptor 2 IMP RGD:5147487 RGD
G Ucn2 urocortin 2 GBrowse link IMP 8 114,003,817 114,005,366 RGD:2317015 RGD
negative regulation of peptide hormone secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link ISO 4 151,492,220 151,617,331 RGD:1624291 RGD
negative regulation of somatostatin secretion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Irs1 insulin receptor substrate 1 GBrowse link IMP 9 81,585,251 81,638,071 RGD:729325 BHF-UCL

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 157111
    negative regulation of biological process 15802
      negative regulation of cellular process 13068
        negative regulation of hormone secretion 114
          negative regulation of activin secretion 0
          negative regulation of adiponectin secretion 2
          negative regulation of corticotropin-releasing hormone secretion 0
          negative regulation of epinephrine secretion 6
          negative regulation of gonadotropin secretion + 12
          negative regulation of inhibin secretion 0
          negative regulation of juvenile hormone secretion 0
          negative regulation of parathyroid hormone secretion 0
          negative regulation of peptide hormone secretion + 74
          negative regulation of steroid hormone secretion + 2
Path 2
Term Annotations click to browse term
  biological_process 157111
    localization 15974
      establishment of localization 11446
        transport 11165
          single-organism transport 9490
            secretion 2194
              secretion by cell 1837
                signal release 756
                  hormone secretion 569
                    regulation of hormone secretion 420
                      negative regulation of hormone secretion 114
                        negative regulation of activin secretion 0
                        negative regulation of adiponectin secretion 2
                        negative regulation of corticotropin-releasing hormone secretion 0
                        negative regulation of epinephrine secretion 6
                        negative regulation of gonadotropin secretion + 12
                        negative regulation of inhibin secretion 0
                        negative regulation of juvenile hormone secretion 0
                        negative regulation of parathyroid hormone secretion 0
                        negative regulation of peptide hormone secretion + 74
                        negative regulation of steroid hormone secretion + 2
paths to the root