ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of hormone secretion
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Accession:GO:0046888 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
Synonyms:exact_synonym: down regulation of hormone secretion;   downregulation of hormone secretion
 narrow_synonym: inhibition of hormone secretion


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negative regulation of hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing GBrowse link 11 84,363,940 84,382,663 RGD:1599138
G Adora1 adenosine A1 receptor GBrowse link 13 56,097,883 56,132,155 RGD:1625242
G Edn1 endothelin 1 GBrowse link 17 24,117,499 24,124,188 RGD:1581817
G Edn2 endothelin 2 GBrowse link 5 142,891,221 142,896,115 RGD:1581817
G Edn3 endothelin 3 GBrowse link 3 178,903,017 178,925,563 RGD:1581817
G Fgf23 fibroblast growth factor 23 GBrowse link 4 231,971,932 231,990,610 RGD:8554413
G Il11 interleukin 11 GBrowse link 1 75,891,524 75,902,590 RGD:1600115
RGD:1624291
G Il6 interleukin 6 GBrowse link 4 3,095,536 3,100,112 RGD:1600115
RGD:1624291
G Lif leukemia inhibitory factor GBrowse link 14 85,163,603 85,181,855 RGD:1600115
RGD:1624291
G Nmb neuromedin B GBrowse link 1 143,673,434 143,676,833 RGD:1642347
G Npy1r neuropeptide Y receptor Y1 GBrowse link 16 24,663,045 24,672,508 RGD:1642321
G Osm oncostatin M GBrowse link 14 85,139,161 85,151,646 RGD:1600115
RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 42,762,630 42,822,760 RGD:1624291
G Ucn urocortin GBrowse link 6 36,418,524 36,419,354 RGD:5490560
negative regulation of adiponectin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Il1b interleukin 1 beta GBrowse link 3 128,133,929 128,140,354 RGD:1600115
RGD:1624291
negative regulation of corticotropin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crhbp corticotropin releasing hormone binding protein GBrowse link 2 44,299,507 44,311,225 RGD:69816
RGD:1600115
RGD:1624291
negative regulation of cortisol secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 42,762,630 42,822,760 RGD:1600115
RGD:1624291
negative regulation of epinephrine secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone GBrowse link 2 124,182,919 124,184,783 RGD:704397
G Crhr1 corticotropin releasing hormone receptor 1 GBrowse link 10 91,953,470 91,995,414 RGD:704397
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 149,943,615 149,986,646 RGD:5131263
G Gabbr1 gamma-aminobutyric acid (GABA) B receptor 1 GBrowse link 20 3,996,333 4,025,508 RGD:2315495
G Gck glucokinase GBrowse link 14 86,832,735 86,875,295 RGD:2301900
G Ptgs1 prostaglandin-endoperoxide synthase 1 GBrowse link 3 20,869,915 20,891,512 RGD:2300224
negative regulation of follicle-stimulating hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 149,943,615 149,986,646 RGD:2317015
G Fst follistatin GBrowse link 2 65,576,721 65,583,918 RGD:69839
G Inha inhibin alpha GBrowse link 9 82,469,743 82,472,644 RGD:2290442
RGD:2290444
G Inhbb inhibin beta-B GBrowse link 13 40,555,699 40,561,388 RGD:1600115
RGD:1624291
G Ucn2 urocortin 2 GBrowse link 8 117,078,961 117,080,510 RGD:2317015
negative regulation of glucagon secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cartpt CART prepropeptide GBrowse link 2 49,285,118 49,287,405 RGD:2313632
G Crh corticotropin releasing hormone GBrowse link 2 124,182,919 124,184,783 RGD:704397
G Lep leptin GBrowse link 4 56,085,079 56,099,209 RGD:1600115
RGD:1624291
negative regulation of glucocorticoid secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Cry1 cryptochrome circadian clock 1 GBrowse link 7
7
24,684,038
26,277,264
24,784,329
26,278,124
RGD:1600115
RGD:1624291
G Cry2 cryptochrome circadian clock 2 GBrowse link 3 88,018,201 88,048,651 RGD:1600115
RGD:1624291
negative regulation of gonadotropin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Npvf neuropeptide VF precursor GBrowse link 4 145,061,114 145,064,805 RGD:1624291
negative regulation of growth hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Madd MAP-kinase activating death domain GBrowse link 3 86,669,054 86,711,776 RGD:9588640
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 42,762,630 42,822,760 RGD:1600115
RGD:1624291
G Sirt1 sirtuin 1 GBrowse link 20 8,139,854 8,159,830 RGD:9585999
negative regulation of insulin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 GBrowse link 1 103,194,473 103,275,508 RGD:1598646
G Acvr1c activin A receptor, type IC GBrowse link 3 49,392,012 49,462,621 RGD:1600115
RGD:1624291
G Adra2a adrenoceptor alpha 2A GBrowse link 1 282,178,475 282,181,275 RGD:1624291
G Bmp8a bone morphogenetic protein 8a GBrowse link 5 144,797,125 144,823,640 RGD:1624291
G Drd2 dopamine receptor D2 GBrowse link 8 52,298,097 52,363,814 RGD:2311570
G Fam3d family with sequence similarity 3, member D GBrowse link 15 22,298,428 22,332,832 RGD:1600115
RGD:1624291
G Ghrl ghrelin/obestatin prepropeptide GBrowse link 4 208,969,963 208,976,778 RGD:1624291
RGD:8553721
G Ghsr growth hormone secretagogue receptor GBrowse link 2 132,784,207 132,789,319 RGD:8553721
G Hadh hydroxyacyl-CoA dehydrogenase GBrowse link 2 254,902,140 254,944,001 RGD:2302227
G Hdac1 histone deacetylase 1 GBrowse link 5 151,445,686 151,472,652 RGD:9590127
G Inhbb inhibin beta-B GBrowse link 13 40,555,699 40,561,388 RGD:1600115
RGD:1624291
G Irs1 insulin receptor substrate 1 GBrowse link 9 87,782,499 87,835,248 RGD:729325
RGD:1600115
RGD:1624291
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 GBrowse link 1 103,186,859 103,190,535 RGD:1600115
RGD:1624291
G Kcnq1 potassium voltage-gated channel, KQT-like subfamily, member 1 GBrowse link 1 223,154,713 223,490,458 RGD:1581603
G Midn midnolin GBrowse link 7 12,584,413 12,594,483 RGD:8655525
G Mtnr1b melatonin receptor 1B GBrowse link 8 14,446,990 14,461,614 RGD:9588673
G Nos1 nitric oxide synthase 1, neuronal GBrowse link 12 46,049,288 46,209,569 RGD:1642149
G Npff neuropeptide FF-amide peptide precursor GBrowse link 7 141,919,079 141,919,868 RGD:2316580
G Park2 parkinson protein 2, E3 ubiquitin protein ligase GBrowse link 1 49,684,308 50,875,397 RGD:1600115
RGD:1624291
G Pde1c phosphodiesterase 1C GBrowse link 4 151,012,195 151,485,775 RGD:2302857
G Pde3b phosphodiesterase 3B, cGMP-inhibited GBrowse link 1 190,865,614 191,050,207 RGD:2302857
G Pde4c phosphodiesterase 4C, cAMP-specific GBrowse link 16 20,298,910 20,318,430 RGD:2302857
G Pde8b phosphodiesterase 8B GBrowse link 2 43,877,817 44,112,405 RGD:2302857
RGD:2312519
G Pfkl phosphofructokinase, liver GBrowse link 20 13,563,748 13,585,941 RGD:1600115
RGD:1624291
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isozyme GBrowse link 2 260,463,144 260,737,186 RGD:2316628
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 GBrowse link 12 40,670,892 40,699,374 RGD:8554418
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 42,762,630 42,822,760 RGD:1600115
RGD:1624291
G Rest RE1-silencing transcription factor GBrowse link 14 32,925,741 32,951,551 RGD:1600115
RGD:1624291
G Sfrp1 secreted frizzled-related protein 1 GBrowse link 16 73,006,739 73,045,509 RGD:1600115
RGD:1624291
G Sirt4 sirtuin 4 GBrowse link 12 48,665,591 48,673,711 RGD:1600115
RGD:1624291
G Srebf1 sterol regulatory element binding transcription factor 1 GBrowse link 10 46,326,015 46,348,035 RGD:1600115
RGD:1624291
G Stxbp5l syntaxin binding protein 5-like GBrowse link 11 69,337,663 69,661,463 RGD:1600115
RGD:1624291
G Sytl4 synaptotagmin-like 4 GBrowse link X 104,598,207 104,648,029 RGD:1600115
RGD:1624291
G Uts2 urotensin 2 GBrowse link 5 171,655,843 171,661,228 RGD:2306798
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A GBrowse link 1 282,178,475 282,181,275 RGD:1600115
RGD:1624291
RGD:2316628
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 149,943,615 149,986,646 RGD:2306172
G Fkbp1b FK506 binding protein 1B GBrowse link 6 39,899,242 39,908,337 RGD:1600115
RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link 2 46,592,881 46,614,276 RGD:5508687
G LOC259246 alpha-2u globulin PGCL1 RGD:1600115
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 GBrowse link 9 46,342,983 46,469,618 RGD:7495848
G Ndufaf2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 GBrowse link 2 58,406,989 58,518,870 RGD:1624291
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase GBrowse link 7 129,544,588 129,547,908 RGD:1600115
RGD:1624291
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) GBrowse link 1 171,707,625 171,713,991 RGD:7204422
negative regulation of luteinizing hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone GBrowse link 2 124,182,919 124,184,783 RGD:5508201
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 149,943,615 149,986,646 RGD:2317015
G Tacr2 tachykinin receptor 2 GBrowse link 20 33,683,625 33,697,583 RGD:5147487
G Ucn2 urocortin 2 GBrowse link 8 117,078,961 117,080,510 RGD:2317015
negative regulation of peptide hormone secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Pparg peroxisome proliferator-activated receptor gamma GBrowse link 4 210,562,928 210,688,585 RGD:1624291
negative regulation of somatostatin secretion term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Irs1 insulin receptor substrate 1 GBrowse link 9 87,782,499 87,835,248 RGD:729325

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 456524
    hormone secretion 1435
      negative regulation of hormone secretion 285
        negative regulation of activin secretion 0
        negative regulation of adiponectin secretion 5
        negative regulation of corticotropin-releasing hormone secretion 0
        negative regulation of epinephrine secretion 18
        negative regulation of gonadotropin secretion + 29
        negative regulation of histamine secretion by mast cell 0
        negative regulation of inhibin secretion 0
        negative regulation of juvenile hormone secretion 0
        negative regulation of parathyroid hormone secretion 0
        negative regulation of peptide hormone secretion + 179
        negative regulation of steroid hormone secretion + 12
Path 2
Term Annotations click to browse term
  biological_process 456524
    localization 50978
      establishment of localization 39888
        transport 39071
          single-organism transport 30974
            secretion 5636
              secretion by cell 4797
                signal release 1944
                  hormone secretion 1435
                    regulation of hormone secretion 1108
                      negative regulation of hormone secretion 285
                        negative regulation of activin secretion 0
                        negative regulation of adiponectin secretion 5
                        negative regulation of corticotropin-releasing hormone secretion 0
                        negative regulation of epinephrine secretion 18
                        negative regulation of gonadotropin secretion + 29
                        negative regulation of histamine secretion by mast cell 0
                        negative regulation of inhibin secretion 0
                        negative regulation of juvenile hormone secretion 0
                        negative regulation of parathyroid hormone secretion 0
                        negative regulation of peptide hormone secretion + 179
                        negative regulation of steroid hormone secretion + 12
paths to the root