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Term:alpha-beta T cell activation
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Accession:GO:0046631 term browser browse the term
Definition:The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:exact_synonym: alpha-beta T lymphocyte activation

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alpha-beta T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dock2 dedicator of cytokinesis 2 GBrowse link ISO 10 19,207,499 19,660,353 RGD:1624291 RGD
G Ins2 insulin 2 GBrowse link ISO 1 202,935,548 202,936,379 RGD:1624291 RGD
alpha-beta T cell activation involved in immune response term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 GBrowse link ISO 20 1,412,553 1,416,692 RGD:1624291 RGD
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 GBrowse link IEA 20 1,412,553 1,416,692 RGD:1600115 ENSEMBL
alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Anxa1 annexin A1 GBrowse link ISO 1 223,478,436 223,494,455 RGD:1624291 RGD
G Anxa1 annexin A1 GBrowse link IEA 1 223,478,436 223,494,455 RGD:1600115 ENSEMBL
G Bcl11b B-cell CLL/lymphoma 11B (zinc finger protein) GBrowse link ISO 6 132,292,671 132,384,572 RGD:1624291 RGD
G Bcl11b B-cell CLL/lymphoma 11B (zinc finger protein) GBrowse link IEA 6 132,292,671 132,384,572 RGD:1600115 ENSEMBL
G Blm Bloom syndrome, RecQ helicase-like GBrowse link ISO 1 136,271,573 136,358,077 RGD:1624291 RGD
G Blm Bloom syndrome, RecQ helicase-like GBrowse link IEA 1 136,271,573 136,358,077 RGD:1600115 ENSEMBL
G Lef1 lymphoid enhancer binding factor 1 GBrowse link ISO 2 228,550,263 228,673,131 RGD:1624291 RGD
G Lef1 lymphoid enhancer binding factor 1 GBrowse link IBA 2 228,550,263 228,673,131 RGD:1600115 RefGenome
G Rpl22 ribosomal protein L22 GBrowse link ISO 5 169,557,840 169,564,566 RGD:1624291 RGD
G Tcf7 transcription factor 7 (T-cell specific, HMG-box) GBrowse link ISO 10 37,686,862 37,716,831 RGD:1624291 RGD
G Tcf7 transcription factor 7 (T-cell specific, HMG-box) GBrowse link IEA 10 37,686,862 37,716,831 RGD:1600115 ENSEMBL
alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dock2 dedicator of cytokinesis 2 GBrowse link ISO 10 19,207,499 19,660,353 RGD:1624291 RGD
beta selection term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Syk spleen tyrosine kinase GBrowse link ISO 17 18,440,672 18,498,001 RGD:1624291 RGD
G Syk spleen tyrosine kinase GBrowse link IEA 17 18,440,672 18,498,001 RGD:1600115 ENSEMBL
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link ISO 9 35,693,089 35,715,071 RGD:1624291 RGD
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link IEA 9 35,693,089 35,715,071 RGD:1600115 ENSEMBL
CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISS 6 44,100,775 44,113,910 RGD:1600115 UniProtKB
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISO 6 44,100,775 44,113,910 RGD:1624291 RGD
G Stoml2 stomatin (Epb7.2)-like 2 GBrowse link ISS 5 59,518,467 59,522,064 RGD:1600115 UniProtKB
CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Nkx2-3 NK2 homeobox 3 GBrowse link ISO 1 247,221,087 247,224,040 RGD:1624291 RGD
G Nkx2-3 NK2 homeobox 3 GBrowse link IEA 1 247,221,087 247,224,040 RGD:1600115 ENSEMBL
G Pax1 paired box 1 GBrowse link ISO 3 136,006,504 136,018,849 RGD:1624291 RGD
G Pax1 paired box 1 GBrowse link IEA 3 136,006,504 136,018,849 RGD:1600115 ENSEMBL
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISS 6 44,100,775 44,113,910 RGD:1600115 UniProtKB
G Rsad2 radical S-adenosyl methionine domain containing 2 GBrowse link ISO 6 44,100,775 44,113,910 RGD:1624291 RGD
G Satb1 SATB homeobox 1 GBrowse link ISO 9 3,307,651 3,391,348 RGD:1624291 RGD
G Satb1 SATB homeobox 1 GBrowse link IEA 9 3,307,651 3,391,348 RGD:1600115 ENSEMBL
CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Foxp3 forkhead box P3 GBrowse link ISO X 26,950,006 26,965,329 RGD:1624291 RGD
G Foxp3 forkhead box P3 GBrowse link ISO X 26,950,006 26,965,329 RGD:1624291 RGD
G Foxp3 forkhead box P3 GBrowse link IEA X 26,950,006 26,965,329 RGD:1600115 ENSEMBL
G Fut7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) GBrowse link ISO 3 3,590,174 3,593,046 RGD:1624291 RGD
G Fut7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) GBrowse link IEA 3 3,590,174 3,593,046 RGD:1600115 ENSEMBL
G Ncor1 nuclear receptor co-repressor 1 GBrowse link ISO 10 48,481,110 48,628,538 RGD:1624291 RGD
CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Irf1 interferon regulatory factor 1 GBrowse link ISO 10 39,220,600 39,227,602 RGD:1624291 RGD
G Irf1 interferon regulatory factor 1 GBrowse link IEA 10 39,220,600 39,227,602 RGD:1600115 ENSEMBL
G Pax1 paired box 1 GBrowse link ISO 3 136,006,504 136,018,849 RGD:1624291 RGD
G Pax1 paired box 1 GBrowse link IEA 3 136,006,504 136,018,849 RGD:1600115 ENSEMBL
G Satb1 SATB homeobox 1 GBrowse link ISO 9 3,307,651 3,391,348 RGD:1624291 RGD
G Satb1 SATB homeobox 1 GBrowse link ISO 9 3,307,651 3,391,348 RGD:1624291 RGD
G Satb1 SATB homeobox 1 GBrowse link IEA 9 3,307,651 3,391,348 RGD:1600115 ENSEMBL
G Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 ISO RGD:1624291 RGD
CD8-positive, alpha-beta T cell differentiation involved in immune response term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Eomes eomesodermin GBrowse link ISO 8 123,376,689 123,383,451 RGD:1624291 RGD
G Eomes eomesodermin GBrowse link ISO 8 123,376,689 123,383,451 RGD:1624291 RGD
G Ifng interferon gamma GBrowse link ISO 7 57,621,756 57,625,792 RGD:1624291 RGD
G Ifng interferon gamma GBrowse link IEA 7 57,621,756 57,625,792 RGD:1600115 ENSEMBL
CD8-positive, alpha-beta T cell lineage commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link ISO 13 12,730,736 12,905,108 RGD:1624291 RGD
G Bcl2 B-cell CLL/lymphoma 2 GBrowse link IEA 13 12,730,736 12,905,108 RGD:1600115 ENSEMBL
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adora2a adenosine A2a receptor GBrowse link ISO 20 13,815,719 13,834,131 RGD:1624291 RGD
G Adora2a adenosine A2a receptor GBrowse link IEA 20 13,815,719 13,834,131 RGD:1600115 ENSEMBL
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gli3 GLI family zinc finger 3 GBrowse link IMP 17 57,594,102 57,867,710 RGD:2290270 BHF-UCL
G Gli3 GLI family zinc finger 3 GBrowse link ISO 17 57,594,102 57,867,710 RGD:1624291 RGD
G Gli3 GLI family zinc finger 3 GBrowse link ISO 17 57,594,102 57,867,710 RGD:2290270 RGD
G Ihh Indian hedgehog GBrowse link ISO 9 74,287,115 74,293,332 RGD:1624291 RGD
G Ihh Indian hedgehog GBrowse link IEA 9 74,287,115 74,293,332 RGD:1600115 ENSEMBL
G Shh sonic hedgehog GBrowse link ISO 4 2,200,504 2,209,657 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link IEA 4 2,200,504 2,209,657 RGD:1600115 ENSEMBL
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Btla B and T lymphocyte associated GBrowse link ISO 11 57,102,004 57,123,067 RGD:1624291 RGD
G Btla B and T lymphocyte associated GBrowse link IEA 11 57,102,004 57,123,067 RGD:1600115 ENSEMBL
G Cblb Cbl proto-oncogene, E3 ubiquitin protein ligase B GBrowse link ISO 11 49,690,402 49,856,762 RGD:1624291 RGD
G Cblb Cbl proto-oncogene, E3 ubiquitin protein ligase B GBrowse link IEA 11 49,690,402 49,856,762 RGD:1600115 ENSEMBL
G Itch itchy E3 ubiquitin protein ligase GBrowse link ISO 3 145,644,315 145,707,190 RGD:1624291 RGD
G Itch itchy E3 ubiquitin protein ligase GBrowse link IEA 3 145,644,315 145,707,190 RGD:1600115 ENSEMBL
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 GBrowse link ISO 5 171,727,707 171,735,340 RGD:1624291 RGD
G Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 GBrowse link IEA 5 171,727,707 171,735,340 RGD:1600115 ENSEMBL
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Xcl1 chemokine (C motif) ligand 1 GBrowse link ISO 13 80,691,195 80,694,638 RGD:1624291 RGD
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Xcl1 chemokine (C motif) ligand 1 GBrowse link ISO 13 80,691,195 80,694,638 RGD:1624291 RGD
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il4r interleukin 4 receptor GBrowse link ISO 1 184,612,903 184,637,863 RGD:1624291 RGD
G Il4r interleukin 4 receptor GBrowse link IEA 1 184,612,903 184,637,863 RGD:1600115 ENSEMBL
G Jak3 Janus kinase 3 GBrowse link ISO 16 18,878,139 18,889,441 RGD:1624291 RGD
G Jak3 Janus kinase 3 GBrowse link ISS 16 18,878,139 18,889,441 RGD:1600115 BHF-UCL
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link IEA 13 77,026,337 77,050,223 RGD:1600115 ENSEMBL
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il4 interleukin 4 GBrowse link ISO 10 39,074,582 39,080,134 RGD:1624291 RGD
G Il4 interleukin 4 GBrowse link IEA 10 39,074,582 39,080,134 RGD:1600115 ENSEMBL
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bcl6 B-cell CLL/lymphoma 6 GBrowse link ISO 11 79,006,123 79,030,555 RGD:1624291 RGD
G Bcl6 B-cell CLL/lymphoma 6 GBrowse link IEA 11 79,006,123 79,030,555 RGD:1600115 ENSEMBL
G Hlx H2.0-like homeobox GBrowse link ISO 13 100,685,757 100,691,658 RGD:1624291 RGD
G Hlx H2.0-like homeobox GBrowse link IEA 13 100,685,757 100,691,658 RGD:1600115 ENSEMBL
G Socs5 suppressor of cytokine signaling 5 GBrowse link ISO 6 10,552,177 10,582,783 RGD:1624291 RGD
G Socs5 suppressor of cytokine signaling 5 GBrowse link IEA 6 10,552,177 10,582,783 RGD:1600115 ENSEMBL
G Zfp35 zinc finger protein 35 GBrowse link ISO 18 15,749,584 15,765,238 RGD:1624291 RGD
negative regulation of T-helper cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rc3h1 ring finger and CCCH-type domains 1 GBrowse link ISO 13 76,493,343 76,530,107 RGD:1624291 RGD
NK T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Itk IL2-inducible T-cell kinase GBrowse link ISO 10 31,455,982 31,518,075 RGD:1624291 RGD
G Itk IL2-inducible T-cell kinase GBrowse link IEA 10 31,455,982 31,518,075 RGD:1600115 ENSEMBL
G Txk TXK tyrosine kinase GBrowse link ISO 14 37,867,565 37,923,075 RGD:1624291 RGD
G Txk TXK tyrosine kinase GBrowse link IEA 14 37,867,565 37,923,075 RGD:1600115 ENSEMBL
NK T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Elf4 E74-like factor 4 (ets domain transcription factor) GBrowse link ISO X 134,808,886 134,818,835 RGD:1624291 RGD
G Elf4 E74-like factor 4 (ets domain transcription factor) GBrowse link IEA X 134,808,886 134,818,835 RGD:1600115 ENSEMBL
G Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor GBrowse link IDA 13 86,867,641 86,877,665 RGD:1304543 RGD
G Il15 interleukin 15 GBrowse link ISO 19 27,487,268 27,498,973 RGD:1624291 RGD
G Il15 interleukin 15 GBrowse link IEA 19 27,487,268 27,498,973 RGD:1600115 ENSEMBL
positive regulation of alpha-beta T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G LOC688090 similar to RT1 class II histocompatibility antigen, B-1 beta chain precursor (RT1.B-beta(1)) IEA RGD:1600115 ENSEMBL
G RT1-Bb RT1 class II, locus Bb GBrowse link ISO 20 4,730,559 4,736,201 RGD:1624291 RGD
G RT1-Bb RT1 class II, locus Bb GBrowse link ISO 20 4,730,559 4,736,201 RGD:1624291 RGD
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ada adenosine deaminase GBrowse link ISO 3 154,636,530 154,660,637 RGD:1624291 RGD
G Ada adenosine deaminase GBrowse link ISO 3 154,636,530 154,660,637 RGD:1624291 RGD
G Ada adenosine deaminase GBrowse link ISO 3 154,636,530 154,660,637 RGD:1624291 RGD
G Ada adenosine deaminase GBrowse link IEA 3 154,636,530 154,660,637 RGD:1600115 ENSEMBL
G Gli3 GLI family zinc finger 3 GBrowse link IMP 17 57,594,102 57,867,710 RGD:2290270 BHF-UCL
G Gli3 GLI family zinc finger 3 GBrowse link ISO 17 57,594,102 57,867,710 RGD:1624291 RGD
G Gli3 GLI family zinc finger 3 GBrowse link ISO 17 57,594,102 57,867,710 RGD:2290270 RGD
G Ihh Indian hedgehog GBrowse link ISO 9 74,287,115 74,293,332 RGD:1624291 RGD
G Ihh Indian hedgehog GBrowse link IEA 9 74,287,115 74,293,332 RGD:1600115 ENSEMBL
G Itpkb inositol-trisphosphate 3-kinase B GBrowse link ISO 13 96,044,260 96,138,456 RGD:1624291 RGD
G Itpkb inositol-trisphosphate 3-kinase B GBrowse link IEA 13 96,044,260 96,138,456 RGD:1600115 ENSEMBL
G Nkap NFKB activating protein GBrowse link ISO X 7,762,215 7,781,862 RGD:1624291 RGD
G Nkap NFKB activating protein GBrowse link ISS X 7,762,215 7,781,862 RGD:1600115 UniProtKB
G Pnp purine nucleoside phosphorylase GBrowse link ISO 15 26,929,784 26,937,434 RGD:1624291 RGD
G Pnp purine nucleoside phosphorylase GBrowse link ISO 15 26,929,784 26,937,434 RGD:1624291 RGD
G Pnp purine nucleoside phosphorylase GBrowse link ISO 15 26,929,784 26,937,434 RGD:1624291 RGD
G Pnp purine nucleoside phosphorylase GBrowse link ISO 15 26,929,784 26,937,434 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link ISO 4 2,200,504 2,209,657 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link IEA 4 2,200,504 2,209,657 RGD:1600115 ENSEMBL
G Shh sonic hedgehog GBrowse link ISS 4 2,200,504 2,209,657 RGD:1600115 UniProtKB
G Syk spleen tyrosine kinase GBrowse link ISO 17 18,440,672 18,498,001 RGD:1624291 RGD
G Syk spleen tyrosine kinase GBrowse link IEA 17 18,440,672 18,498,001 RGD:1600115 ENSEMBL
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link ISO 9 35,693,089 35,715,071 RGD:1624291 RGD
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link ISO 9 35,693,089 35,715,071 RGD:1624291 RGD
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link ISO 9 35,693,089 35,715,071 RGD:1624291 RGD
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link IEA 9 35,693,089 35,715,071 RGD:1600115 ENSEMBL
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Blm Bloom syndrome, RecQ helicase-like GBrowse link ISO 1 136,271,573 136,358,077 RGD:1624291 RGD
G Blm Bloom syndrome, RecQ helicase-like GBrowse link IEA 1 136,271,573 136,358,077 RGD:1600115 ENSEMBL
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link ISS 8 128,892,784 128,893,905 RGD:1600115 BHF-UCL
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link ISO 20 47,502,354 47,507,663 RGD:1624291 RGD
G Cd24 CD24 molecule GBrowse link IEA 20 47,502,354 47,507,663 RGD:1600115 ENSEMBL
G Cd28 Cd28 molecule GBrowse link ISO 9 59,342,273 59,367,743 RGD:1624291 RGD
G Cd28 Cd28 molecule GBrowse link ISO 9 59,342,273 59,367,743 RGD:1624291 RGD
G Cd28 Cd28 molecule GBrowse link ISO 9 59,342,273 59,367,743 RGD:1624291 RGD
G Cd28 Cd28 molecule GBrowse link IEA 9 59,342,273 59,367,743 RGD:1600115 ENSEMBL
G Cd3e CD3 molecule, epsilon GBrowse link ISO 8 47,947,257 47,958,419 RGD:1624291 RGD
G Cd3e CD3 molecule, epsilon GBrowse link ISO 8 47,947,257 47,958,419 RGD:1624291 RGD
G Cd3e CD3 molecule, epsilon GBrowse link ISO 8 47,947,257 47,958,419 RGD:1624291 RGD
G Cd3e CD3 molecule, epsilon GBrowse link IEA 8 47,947,257 47,958,419 RGD:1600115 ENSEMBL
G Cd80 Cd80 molecule GBrowse link ISO 11 64,045,358 64,070,072 RGD:1624291 RGD
G Cd80 Cd80 molecule GBrowse link IEA 11 64,045,358 64,070,072 RGD:1600115 ENSEMBL
G Ptprc protein tyrosine phosphatase, receptor type, C GBrowse link ISO 13 51,246,163 51,357,995 RGD:1624291 RGD
G Ptprc protein tyrosine phosphatase, receptor type, C GBrowse link IEA 13 51,246,163 51,357,995 RGD:1600115 ENSEMBL
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
G Syk spleen tyrosine kinase GBrowse link ISO 17 18,440,672 18,498,001 RGD:1624291 RGD
G Syk spleen tyrosine kinase GBrowse link IEA 17 18,440,672 18,498,001 RGD:1600115 ENSEMBL
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link IEA 13 77,026,337 77,050,223 RGD:1600115 ENSEMBL
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link ISO 9 35,693,089 35,715,071 RGD:1624291 RGD
G Zap70 zeta-chain (TCR) associated protein kinase 70 GBrowse link IEA 9 35,693,089 35,715,071 RGD:1600115 ENSEMBL
positive regulation of CD4-positive, alpha beta T cell costimulation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link IEA 13 77,026,337 77,050,223 RGD:1600115 ENSEMBL
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd83 CD83 molecule GBrowse link ISO 17 26,705,646 26,725,470 RGD:1624291 RGD
G Cd83 CD83 molecule GBrowse link IEA 17 26,705,646 26,725,470 RGD:1600115 ENSEMBL
G Nckap1l NCK associated protein 1 like GBrowse link ISO 7 142,351,954 142,397,045 RGD:1624291 RGD
G Nckap1l NCK associated protein 1 like GBrowse link IEA 7 142,351,954 142,397,045 RGD:1600115 ENSEMBL
G Sash3 SAM and SH3 domain containing 3 GBrowse link ISO X 134,511,776 134,526,489 RGD:1624291 RGD
G Sash3 SAM and SH3 domain containing 3 GBrowse link IEA X 134,511,776 134,526,489 RGD:1600115 ENSEMBL
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Xcl1 chemokine (C motif) ligand 1 GBrowse link ISO 13 80,691,195 80,694,638 RGD:1624291 RGD
G Xcl1 chemokine (C motif) ligand 1 GBrowse link IEA 13 80,691,195 80,694,638 RGD:1600115 ENSEMBL
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Foxp3 forkhead box P3 GBrowse link ISO X 26,950,006 26,965,329 RGD:1624291 RGD
G Foxp3 forkhead box P3 GBrowse link ISO X 26,950,006 26,965,329 RGD:1624291 RGD
G Foxp3 forkhead box P3 GBrowse link IBA X 26,950,006 26,965,329 RGD:1600115 RefGenome
G Gimap5 GTPase, IMAP family member 5 GBrowse link IMP 4 76,836,521 76,843,214 RGD:2303772 RGD
G Il2rg interleukin 2 receptor, gamma GBrowse link ISO X 89,342,055 89,345,715 RGD:1624291 RGD
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Nckap1l NCK associated protein 1 like GBrowse link ISO 7 142,351,954 142,397,045 RGD:1624291 RGD
G Nckap1l NCK associated protein 1 like GBrowse link IEA 7 142,351,954 142,397,045 RGD:1600115 ENSEMBL
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Xcl1 chemokine (C motif) ligand 1 GBrowse link ISO 13 80,691,195 80,694,638 RGD:1624291 RGD
positive regulation of NK T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd1d1 CD1d1 molecule GBrowse link ISO 2 179,011,165 179,014,672 RGD:1624291 RGD
G Cd1d1 CD1d1 molecule GBrowse link ISO 2 179,011,165 179,014,672 RGD:1624291 RGD
G Cd1d1 CD1d1 molecule GBrowse link ISO 2 179,011,165 179,014,672 RGD:1624291 RGD
G Il12a interleukin 12A GBrowse link ISO 2 158,710,261 158,717,689 RGD:1624291 RGD
G Il12a interleukin 12A GBrowse link IEA 2 158,710,261 158,717,689 RGD:1600115 ENSEMBL
G Il12b interleukin 12B GBrowse link ISO 10 29,558,955 29,568,331 RGD:1624291 RGD
G Il23a Interleukin 23, alpha subunit p19 GBrowse link ISO 7 1,584,112 1,586,226 RGD:1624291 RGD
G Il23a Interleukin 23, alpha subunit p19 GBrowse link IEA 7 1,584,112 1,586,226 RGD:1600115 ENSEMBL
positive regulation of NK T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit GBrowse link ISO 2 24,670,078 24,872,770 RGD:1624291 RGD
G Ap3b1 adaptor-related protein complex 3, beta 1 subunit GBrowse link IEA 2 24,670,078 24,872,770 RGD:1600115 ENSEMBL
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit GBrowse link ISO 7 10,480,810 10,516,163 RGD:1624291 RGD
G Ap3d1 adaptor-related protein complex 3, delta 1 subunit GBrowse link IEA 7 10,480,810 10,516,163 RGD:1600115 ENSEMBL
G Cd1d1 CD1d1 molecule GBrowse link ISO 2 179,011,165 179,014,672 RGD:1624291 RGD
G Cd1d1 CD1d1 molecule GBrowse link ISO 2 179,011,165 179,014,672 RGD:1624291 RGD
G Ikzf1 IKAROS family zinc finger 1 GBrowse link ISO 14 92,560,200 92,657,336 RGD:1624291 RGD
G Ikzf1 IKAROS family zinc finger 1 GBrowse link IEA 14 92,560,200 92,657,336 RGD:1600115 ENSEMBL
G Tgfbr2 transforming growth factor, beta receptor II GBrowse link ISO 8 120,593,595 120,680,453 RGD:1624291 RGD
G Tgfbr2 transforming growth factor, beta receptor II GBrowse link IEA 8 120,593,595 120,680,453 RGD:1600115 ENSEMBL
positive regulation of NK T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il12b interleukin 12B GBrowse link ISO 10 29,558,955 29,568,331 RGD:1624291 RGD
G Il18 interleukin 18 GBrowse link ISO 8 53,936,584 53,943,228 RGD:1624291 RGD
G Il18 interleukin 18 GBrowse link IEA 8 53,936,584 53,943,228 RGD:1600115 ENSEMBL
G Il23a Interleukin 23, alpha subunit p19 GBrowse link ISO 7 1,584,112 1,586,226 RGD:1624291 RGD
G Il23a Interleukin 23, alpha subunit p19 GBrowse link IEA 7 1,584,112 1,586,226 RGD:1600115 ENSEMBL
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hlx H2.0-like homeobox GBrowse link ISO 13 100,685,757 100,691,658 RGD:1624291 RGD
G Hlx H2.0-like homeobox GBrowse link IEA 13 100,685,757 100,691,658 RGD:1600115 ENSEMBL
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link ISO 5 30,714,817 30,745,941 RGD:1624291 RGD
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 5 30,714,817 30,745,941 RGD:1600115 ENSEMBL
G Socs5 suppressor of cytokine signaling 5 GBrowse link ISO 6 10,552,177 10,582,783 RGD:1624291 RGD
G Socs5 suppressor of cytokine signaling 5 GBrowse link IEA 6 10,552,177 10,582,783 RGD:1600115 ENSEMBL
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il23a Interleukin 23, alpha subunit p19 GBrowse link ISO 7 1,584,112 1,586,226 RGD:1624291 RGD
G Il23a Interleukin 23, alpha subunit p19 GBrowse link IEA 7 1,584,112 1,586,226 RGD:1600115 ENSEMBL
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Prkcq protein kinase C, theta GBrowse link ISO 17 78,486,998 78,566,741 RGD:1624291 RGD
G Prkcq protein kinase C, theta GBrowse link IEA 17 78,486,998 78,566,741 RGD:1600115 ENSEMBL
G Prkcq protein kinase C, theta GBrowse link ISS 17 78,486,998 78,566,741 RGD:1600115 UniProtKB
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il4r interleukin 4 receptor GBrowse link ISO 1 184,612,903 184,637,863 RGD:1624291 RGD
G Il4r interleukin 4 receptor GBrowse link IEA 1 184,612,903 184,637,863 RGD:1600115 ENSEMBL
G Il6 interleukin 6 GBrowse link ISO 4 456,799 461,376 RGD:1624291 RGD
G Il6 interleukin 6 GBrowse link IEA 4 456,799 461,376 RGD:1600115 ENSEMBL
G Prkcz protein kinase C, zeta GBrowse link ISO 5 172,061,825 172,172,793 RGD:1624291 RGD
G Prkcz protein kinase C, zeta GBrowse link ISS 5 172,061,825 172,172,793 RGD:1600115 UniProtKB
G Rara retinoic acid receptor, alpha GBrowse link ISO 10 87,740,479 87,753,265 RGD:1624291 RGD
G Rara retinoic acid receptor, alpha GBrowse link IEA 10 87,740,479 87,753,265 RGD:1600115 ENSEMBL
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link IEA 13 77,026,337 77,050,223 RGD:1600115 ENSEMBL
regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gata3 GATA binding protein 3 GBrowse link ISO 17 79,991,587 80,011,574 RGD:1624291 RGD
G Gata3 GATA binding protein 3 GBrowse link IEA 17 79,991,587 80,011,574 RGD:1600115 ENSEMBL
G Zbtb7b zinc finger and BTB domain containing 7B GBrowse link ISO 2 181,576,165 181,578,156 RGD:1624291 RGD
regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Zbtb7b zinc finger and BTB domain containing 7B GBrowse link ISO 2 181,576,165 181,578,156 RGD:1624291 RGD
regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Irf1 interferon regulatory factor 1 GBrowse link ISO 10 39,220,600 39,227,602 RGD:1624291 RGD
G Irf1 interferon regulatory factor 1 GBrowse link ISS 10 39,220,600 39,227,602 RGD:1600115 UniProtKB
G Irf1 interferon regulatory factor 1 GBrowse link IEA 10 39,220,600 39,227,602 RGD:1600115 ENSEMBL
regulation of NK T cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cxcr6 chemokine (C-X-C motif) receptor 6 GBrowse link IEA 8 128,569,564 128,570,619 RGD:1600115 InterPro
regulation of T-helper 1 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il27 interleukin 27 GBrowse link IEA 1 185,730,394 185,735,604 RGD:1600115 ENSEMBL
G Il27 interleukin 27 GBrowse link ISO 1 185,730,394 185,735,604 RGD:1624291 RGD
regulation of T-helper cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il12rb2 interleukin 12 receptor, beta 2 GBrowse link NAS 4 96,929,755 96,995,733 RGD:1331512 RGD
T-helper 1 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il18r1 interleukin 18 receptor 1 GBrowse link ISO 9 39,627,915 39,659,828 RGD:1624291 RGD
G Lef1 lymphoid enhancer binding factor 1 GBrowse link ISO 2 228,550,263 228,673,131 RGD:1624291 RGD
G Lef1 lymphoid enhancer binding factor 1 GBrowse link IEA 2 228,550,263 228,673,131 RGD:1600115 ENSEMBL
G Relb v-rel reticuloendotheliosis viral oncogene homolog B ISO RGD:1624291 RGD
G Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A GBrowse link ISO 2 180,552,405 180,570,359 RGD:1624291 RGD
G Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A GBrowse link IEA 2 180,552,405 180,570,359 RGD:1600115 ENSEMBL
T-helper 1 cell lineage commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Il4 interleukin 4 GBrowse link ISO 10 39,074,582 39,080,134 RGD:1624291 RGD
G Il4 interleukin 4 GBrowse link IEA 10 39,074,582 39,080,134 RGD:1600115 ENSEMBL
G Stat6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link ISO 7 67,623,534 67,642,283 RGD:1624291 RGD
G Stat6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link IEA 7 67,623,534 67,642,283 RGD:1600115 ENSEMBL
T-helper 17 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISS 6 109,793,076 109,817,614 RGD:1600115 UniProtKB
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
T-helper 17 cell lineage commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISS 6 109,793,076 109,817,614 RGD:1600115 UniProtKB
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
G Irf4 interferon regulatory factor 4 GBrowse link ISO 17 40,170,409 40,189,976 RGD:1624291 RGD
T-helper 2 cell activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link ISO 13 77,026,337 77,050,223 RGD:1624291 RGD
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 GBrowse link IEA 13 77,026,337 77,050,223 RGD:1600115 ENSEMBL
T-helper 2 cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISS 6 109,793,076 109,817,614 RGD:1600115 UniProtKB
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
G Batf basic leucine zipper transcription factor, ATF-like GBrowse link ISO 6 109,793,076 109,817,614 RGD:1624291 RGD
G Bcl3 B-cell CLL/lymphoma 3 GBrowse link ISO 1 79,122,801 79,137,035 RGD:1624291 RGD
G Bcl3 B-cell CLL/lymphoma 3 GBrowse link IEA 1 79,122,801 79,137,035 RGD:1600115 ENSEMBL
G Gata3 GATA binding protein 3 GBrowse link ISO 17 79,991,587 80,011,574 RGD:1624291 RGD
G Gata3 GATA binding protein 3 GBrowse link IEA 17 79,991,587 80,011,574 RGD:1600115 ENSEMBL
G Il4 interleukin 4 GBrowse link ISO 10 39,074,582 39,080,134 RGD:1624291 RGD
G Il4 interleukin 4 GBrowse link IEA 10 39,074,582 39,080,134 RGD:1600115 ENSEMBL
T-helper cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Atp7a ATPase, Cu++ transporting, alpha polypeptide GBrowse link ISO X 94,192,540 94,249,776 RGD:1624291 RGD
G Atp7a ATPase, Cu++ transporting, alpha polypeptide GBrowse link IEA X 94,192,540 94,249,776 RGD:1600115 ENSEMBL
G Il12b interleukin 12B GBrowse link ISO 10 29,558,955 29,568,331 RGD:1624291 RGD
G Ptger4 prostaglandin E receptor 4 (subtype EP4) GBrowse link ISO 2 54,423,280 54,433,907 RGD:1624291 RGD
G Ptger4 prostaglandin E receptor 4 (subtype EP4) GBrowse link ISS 2 54,423,280 54,433,907 RGD:1600115 UniProtKB
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    immune system process 6124
      leukocyte activation 1882
        lymphocyte activation 1639
          T cell activation 1060
            alpha-beta T cell activation 262
              CD4-positive, alpha-beta T cell activation + 111
              CD8-positive, alpha-beta T cell activation + 21
              NK T cell activation + 9
              alpha-beta T cell activation by superantigen 0
              alpha-beta T cell activation involved in immune response + 74
              alpha-beta T cell differentiation + 176
              alpha-beta T cell proliferation + 57
              negative regulation of alpha-beta T cell activation + 35
              positive regulation of alpha-beta T cell activation + 121
              regulation of alpha-beta T cell activation + 169
Path 2
Term Annotations click to browse term
  biological_process 135967
    cellular process 85138
      single-organism cellular process 56334
        cell activation 2072
          leukocyte activation 1882
            lymphocyte activation 1639
              T cell activation 1060
                alpha-beta T cell activation 262
                  CD4-positive, alpha-beta T cell activation + 111
                  CD8-positive, alpha-beta T cell activation + 21
                  NK T cell activation + 9
                  alpha-beta T cell activation by superantigen 0
                  alpha-beta T cell activation involved in immune response + 74
                  alpha-beta T cell differentiation + 176
                  alpha-beta T cell proliferation + 57
                  negative regulation of alpha-beta T cell activation + 35
                  positive regulation of alpha-beta T cell activation + 121
                  regulation of alpha-beta T cell activation + 169
paths to the root

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