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ONTOLOGY REPORT - ANNOTATIONS

Term:ceramide biosynthetic process
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Accession:GO:0046513 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
Synonyms:exact_synonym: ceramide anabolism;   ceramide biosynthesis;   ceramide formation;   ceramide synthesis


show annotations for term's descendants           Sort by:
ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer3 alkaline ceramidase 3 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:152,504,180...152,606,596
Ensembl chr 1:152,504,186...152,606,591 		JBrowse link
G Agk acylglycerol kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:15252046)		 GO_Central
RGD		 PMID:15252046 GO_REF:0000033 NCBI chr 4:69,114,850...69,193,989
Ensembl chr 4:69,114,269...69,193,934 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:3789553|PMID:17403930)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17403930 GO_REF:0000024 GO_REF:0000107 MGI:3789553 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:5496904 (PMID:22832496)
(MGI:5488571|PMID:22832496)		 UniProt
RGD		 PMID:22832496 GO_REF:0000024 MGI:5488571 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 involved_in ISO
ISS		 (PMID:12764132), (PMID:12815059)
GO_REF:0000024		 RGD
UniProt		 PMID:12764132 PMID:12815059 GO_REF:0000024 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
IDA		 (PMID:11278489), (PMID:17475390)
(MGI:6274955|PMID:21613224)
PMID:15123644		 RGD PMID:11278489 PMID:17475390 PMID:21613224 PMID:15123644 PMID:11278489 MGI:6274955, RGD:13838793, RGD:13838803 NCBI chr 1:229,865,662...229,973,253
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO
IBA		 (PMID:12105227), (PMID:12869556), (PMID:15823095), (PMID:17548428), (PMID:18541923), (PMID:22922758), (PMID:24782409)
GO_REF:0000033
(MGI:3696321|PMID:16951403), (MGI:3764760|PMID:17977534), (MGI:5008665|PMID:21625621), (MGI:5755322|PMID:26620563), (MGI:6380950|PMID:30605666)		 RGD
GO_Central		 PMID:12105227 PMID:12869556 PMID:15823095 PMID:16951403 PMID:17548428 More... GO_REF:0000033 MGI:3696321 MGI:3764760 MGI:5008665 MGI:5755322 MGI:6380950 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers2 ceramide synthase 2 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:18165233), (PMID:29632068)
(PMID:15823095)
GO_REF:0000033
(MGI:4421488|PMID:19801672), (MGI:5755322|PMID:26620563)		 RGD
GO_Central		 PMID:15823095 PMID:17977534 PMID:18165233 PMID:19801672 PMID:26620563 More... GO_REF:0000033 MGI:4421488 MGI:5755322 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314 		JBrowse link
G Cers3 ceramide synthase 3 involved_in ISO
IBA		 (PMID:17977534), (PMID:22038835), (PMID:23754960)
GO_REF:0000033
(MGI:5303015|PMID:22038835)		 RGD
GO_Central		 PMID:17977534 PMID:22038835 PMID:23754960 GO_REF:0000033 MGI:5303015 NCBI chr 1:120,316,930...120,422,926
Ensembl chr 1:120,318,212...120,422,902 		JBrowse link
G Cers4 ceramide synthase 4 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17977534), (PMID:29632068)
(PMID:12912983), (PMID:15823095)
GO_REF:0000033		 RGD
GO_Central		 PMID:12912983 PMID:15823095 PMID:17977534 PMID:29632068 GO_REF:0000033 NCBI chr12:2,851,784...2,890,244
Ensembl chr12:2,851,784...2,886,828 		JBrowse link
G Cers5 ceramide synthase 5 involved_in ISO
IBA		 (PMID:16951403), (PMID:29632068)
GO_REF:0000033
(MGI:3696624|PMID:16100120), (MGI:3722529|PMID:17609214), (MGI:3764760|PMID:17977534)		 RGD
GO_Central		 PMID:16100120 PMID:16951403 PMID:17609214 PMID:17977534 PMID:29632068 GO_REF:0000033 MGI:3696624 MGI:3722529 MGI:3764760 NCBI chr 7:130,859,993...130,897,979
Ensembl chr 7:130,859,990...130,897,947 		JBrowse link
G Cers6 ceramide synthase 6 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:17609214), (PMID:17977534)
(PMID:15823095)
GO_REF:0000033
(MGI:5513027|PMID:23760501), (MGI:5755322|PMID:26620563)		 RGD
GO_Central		 PMID:15823095 PMID:17609214 PMID:17977534 PMID:23760501 PMID:26620563 GO_REF:0000033 MGI:5513027 MGI:5755322 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 involved_in ISO
IBA		 (PMID:26056268)
GO_REF:0000033		 RGD
GO_Central		 PMID:26056268 GO_REF:0000033 NCBI chr 7:11,426,806...11,505,553
Ensembl chr 7:11,433,371...11,536,181 		JBrowse link
G Degs1 delta(4)-desaturase, sphingolipid 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3529540 (PMID:22984457)		 GO_Central
RGD		 PMID:22984457 GO_REF:0000033 NCBI chr13:93,946,154...93,953,677
Ensembl chr13:93,946,157...93,953,664 		JBrowse link
G Degs1l1 delta(4)-desaturase, sphingolipid 1 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:92,772,654...92,818,811
Ensembl chr13:92,772,649...92,818,574 		JBrowse link
G Degs1l2 delta(4)-desaturase, sphingolipid 1 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:92,831,549...92,839,257
Ensembl chr13:92,831,537...92,839,246 		JBrowse link
G Degs2 delta(4)-desaturase, sphingolipid 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:127,596,063...127,613,293
Ensembl chr 6:127,596,071...127,613,293 		JBrowse link
G Elovl1 ELOVL fatty acid elongase 1 involved_in ISO (MGI:5532629|PMID:23689133) RGD PMID:23689133 MGI:5532629 NCBI chr 5:131,961,478...131,965,961
Ensembl chr 5:131,961,322...131,965,958 		JBrowse link
G ENSRNOG00000069695 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr14:25,729,638...25,730,194 JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISO
ISS		 (PMID:15337768)
(MGI:6245295|PMID:22517924)
GO_REF:0000024		 RGD
UniProt		 PMID:15337768 PMID:22517924 GO_REF:0000024 MGI:6245295 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gba1 glucosylceramidase beta 1 involved_in ISO (PMID:19279011) RGD PMID:19279011 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO (PMID:16325464) RGD PMID:16325464 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO (PMID:16325464) RGD PMID:16325464 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:27751867)
(MGI:5882269|PMID:27751867)		 RGD PMID:27751867 MGI:5882269 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:19506037)
MGI:5749225 (PMID:25605874), (PMID:25667419)
GO_REF:0000033		 RGD
GO_Central		 PMID:19506037 PMID:25605874 PMID:25667419 GO_REF:0000033 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
G Sgms1 sphingomyelin synthase 1 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25605874)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:25605874 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:229,996,673...230,259,591
Ensembl chr 1:229,998,119...230,259,603 		JBrowse link
G Sgms2 sphingomyelin synthase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:4818459 (PMID:25605874)
GO_REF:0000033
GO_REF:0000118		 Ensembl
RGD
GO_Central
TreeGrafter		 PMID:25605874 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:219,889,809...219,967,704
Ensembl chr 2:219,893,572...219,967,546 		JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 involved_in IMP
ISO
IBA		 (MGI:82530|PMID:8706124), (PMID:35705808)
GO_REF:0000033
(PMID:17303575), (PMID:18815062), (PMID:19279011), (PMID:20807762), (PMID:33163980), (PMID:8706124)		 RGD
GO_Central		 PMID:8706124 PMID:17303575 PMID:18815062 PMID:19279011 PMID:20807762 More... GO_REF:0000033 MGI:82530, RGD:1601344 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794 		JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12473648 GO_REF:0000033, RGD:1581395 NCBI chr20:44,986,229...44,989,343
Ensembl chr20:44,986,231...44,989,441 		JBrowse link
G Smpd4 sphingomyelin phosphodiesterase 4 involved_in ISO
IBA		 (PMID:16517606), (PMID:25180167)
GO_REF:0000033
(MGI:6450503|PMID:25180167)		 RGD
GO_Central		 PMID:16517606 PMID:25180167 GO_REF:0000033 MGI:6450503 NCBI chr11:83,362,534...83,386,257
Ensembl chr11:83,362,534...83,386,250 		JBrowse link
G Smpd5 sphingomyelin phosphodiesterase 5 involved_in ISO (MGI:6450238|PMID:21183079) RGD PMID:21183079 MGI:6450238 NCBI chr 7:108,009,182...108,011,767
Ensembl chr 7:108,009,173...108,011,763 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:25691431)
MGI:3815115 (PMID:16216550)
GO_REF:0000118
GO_REF:0000033		 RGD
TreeGrafter
GO_Central		 PMID:16216550 PMID:25691431 GO_REF:0000033 GO_REF:0000118 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25691431)
MGI:3815117 (PMID:16216550)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:16216550 PMID:25691431 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:106,948,682...107,031,532
Ensembl chr 6:106,950,949...107,031,542 		JBrowse link
G Sptlc3 serine palmitoyltransferase, long chain base subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010 		JBrowse link
G Sptssa serine palmitoyltransferase, small subunit A acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:25691431)
GO_REF:0000033		 RGD
GO_Central		 PMID:25691431 GO_REF:0000033 NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214 		JBrowse link
G Sptssb serine palmitoyltransferase, small subunit B acts_upstream_of_or_within ISO MGI:5689843 (PMID:26438849) RGD PMID:26438849 NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120 		JBrowse link
G Tlcd3b TLC domain containing 3B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:23275342)		 GO_Central
RGD		 PMID:23275342 GO_REF:0000033 NCBI chr 1:181,421,104...181,439,744
Ensembl chr 1:181,422,830...181,439,743 		JBrowse link
galactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt1 Beta-1,3-galactosyltransferase 1 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr 3:52,253,413...52,826,508
Ensembl chr 3:52,253,618...52,825,313 		JBrowse link
G B3galt2 Beta-1,3-galactosyltransferase 2 involved_in ISO (PMID:9582303) RGD PMID:9582303 NCBI chr13:55,389,406...55,398,419
Ensembl chr13:55,389,406...55,398,419 		JBrowse link
G B4galt3 beta-1,4-galactosyltransferase 3 involved_in ISO
IBA
IEA		 (PMID:9405390)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:9405390 GO_REF:0000033 GO_REF:0000107 NCBI chr13:83,691,378...83,697,448
Ensembl chr13:83,691,446...83,697,448 		JBrowse link
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO
IMP
IEA		 GO_REF:0000024
(MGI:3696647|PMID:15658937), (MGI:3826747|PMID:18815260)
PMID:17901466
GO_REF:0000041		 UniProt
RGD		 PMID:15658937 PMID:18815260 PMID:17901466 GO_REF:0000024 GO_REF:0000041 MGI:3696647 MGI:3826747, RGD:13825191 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Gal3st1 galactose-3-O-sulfotransferase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10727929)		 GO_Central
RGD		 PMID:10727929 GO_REF:0000033 NCBI chr14:78,868,049...78,886,402
Ensembl chr14:78,870,793...78,886,388 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 involved_in IDA
IBA
IEA		 PMID:8713090
GO_REF:0000033
GO_REF:0000041		 GO_Central
UniProt		 PMID:8713090 GO_REF:0000033 GO_REF:0000041, RGD:39458006 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 Beta-1,3-galactosyltransferase 4 involved_in ISO
IEA		 (PMID:9582303)
GO_REF:0000107		 RGD
Ensembl		 PMID:9582303 GO_REF:0000107 NCBI chr20:4,936,089...4,937,664
Ensembl chr20:4,931,768...4,938,315 		JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA
IDA		 GO_REF:0000024
MGI:2158349|MGI:96074 (PMID:10021458)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(MGI:83232|PMID:8855236)
PMID:3140234
(PMID:1601877), (PMID:7487055), (PMID:7890749)		 UniProt
RGD
GO_Central
TreeGrafter
Ensembl		 PMID:1601877 PMID:7487055 PMID:7890749 PMID:8855236 PMID:10021458 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:83232, RGD:21201261 NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190 		JBrowse link
G Rps18 ribosomal protein S18 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146 		JBrowse link
G St6galnac3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:242,129,755...242,645,120
Ensembl chr 2:242,129,763...242,645,133 		JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243 		JBrowse link
G St6galnac5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:241,741,933...241,911,214
Ensembl chr 2:241,742,688...241,911,208 		JBrowse link
G St6galnac6 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10702226)		 GO_Central
RGD		 PMID:10702226 GO_REF:0000033 NCBI chr 3:15,894,275...15,907,502
Ensembl chr 3:15,885,968...15,907,496 		JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 1:127,762,573...127,838,017
Ensembl chr 1:127,762,573...127,838,091 		JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO (PMID:10766765)
(MGI:74245|PMID:7782326)		 RGD PMID:7782326 PMID:10766765 MGI:74245 NCBI chr18:57,754,349...57,760,839
Ensembl chr18:57,754,347...57,760,839 		JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in ISO (PMID:10766765) RGD PMID:10766765 NCBI chr 9:95,990,131...96,084,661
Ensembl chr 9:95,993,503...96,084,653 		JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in ISO (MGI:2182536|PMID:11980897) RGD PMID:11980897 MGI:2182536 NCBI chr17:76,740,755...76,884,178
Ensembl chr17:76,745,224...76,884,299 		JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt5 beta-1,4-galactosyltransferase 5 involved_in ISO (MGI:6196231|PMID:30114188) RGD PMID:30114188 MGI:6196231 NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6196231|PMID:30114188)		 UniProt
RGD		 PMID:30114188 GO_REF:0000024 MGI:6196231 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
G C3h20orf173 similar to human chromosome 20 open reading frame 173 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 3:144,514,060...144,524,979
Ensembl chr 3:144,519,930...144,524,920 		JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in ISO
IBA		 (PMID:8027041)
GO_REF:0000033
(MGI:65558|PMID:8144500)		 RGD
GO_Central		 PMID:8027041 PMID:8144500 GO_REF:0000033 MGI:65558 NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236 		JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IDA
IBA
IEA
ISO		 PMID:8144500
GO_REF:0000033
GO_REF:0000117
(MGI:6467685|PMID:22735313), (MGI:65558|PMID:8144500)
(PMID:8920913)		 GO_Central
UniProt
RGD		 PMID:8144500 PMID:8920913 PMID:22735313 PMID:8144500 GO_REF:0000033 GO_REF:0000117 MGI:6467685 MGI:65558, RGD:68307 NCBI chr19:38,888,851...38,939,874
Ensembl chr19:38,923,999...38,939,869 		JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6467685|PMID:22735313)		 Ensembl
RGD		 PMID:22735313 GO_REF:0000107 MGI:6467685 NCBI chr 5:131,470,348...131,670,794
Ensembl chr 5:131,470,348...131,670,810 		JBrowse link
glucosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fa2h fatty acid 2-hydroxylase involved_in ISS
ISO		 GO_REF:0000024
(MGI:5285470|PMID:21628453)		 UniProt
RGD		 PMID:21628453 GO_REF:0000024 MGI:5285470 NCBI chr19:39,312,904...39,364,153
Ensembl chr19:39,312,906...39,364,153 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase involved_in ISO
IBA
ISS		 (PMID:8643456)
GO_REF:0000033
(MGI:2180222|PMID:10430909), (MGI:3603060|PMID:16109770), (MGI:5448789|PMID:22851168), (MGI:5510915|PMID:23748427)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:8643456 PMID:10430909 PMID:16109770 PMID:22851168 PMID:23748427 GO_REF:0000024 GO_REF:0000033 MGI:2180222 MGI:3603060 MGI:5448789 MGI:5510915 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
lactosylceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4galt4 beta-1,4-galactosyltransferase 4 involved_in ISO
ISS		 (PMID:9792633)
GO_REF:0000024		 RGD
UniProt		 PMID:9792633 GO_REF:0000024 NCBI chr11:61,995,807...62,021,751
Ensembl chr11:61,995,814...62,021,671 		JBrowse link
G B4galt6 beta-1,4-galactosyltransferase 6 involved_in ISO (PMID:10320813) RGD PMID:10320813 NCBI chr18:11,958,382...12,015,247
Ensembl chr18:11,958,390...12,015,247 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) RGD PMID:25691431 NCBI chr 7:1,247,869...1,250,999
Ensembl chr 7:1,246,479...1,250,907 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:25691431)		 Ensembl
RGD		 PMID:25691431 GO_REF:0000107 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:6294167|PMID:16118219)
(PMID:16118219)		 UniProt
Ensembl
RGD		 PMID:16118219 GO_REF:0000024 GO_REF:0000107 MGI:6294167 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
omega-hydroxyceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpla1 patatin-like phospholipase domain containing 1 involved_in ISO (PMID:28248318)
(MGI:5888934|PMID:28248300)		 RGD PMID:28248300 PMID:28248318 MGI:5888934 NCBI chr20:6,917,993...6,952,157
Ensembl chr20:6,917,931...6,952,375 		JBrowse link
positive regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:19364818) RGD PMID:19364818 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947032|PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 MGI:4947032 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Pla2g6 phospholipase A2 group VI involved_in IDA
IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central
RGD		 PMID:18936091 GO_REF:0000033 GO_REF:0000118, RGD:6482750 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
IEA		 (PMID:19279011)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279011 GO_REF:0000107 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO (MGI:5755322|PMID:26620563) RGD PMID:26620563 MGI:5755322 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IMP RGD PMID:20096352 RGD:10041064 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:16118219)
(MGI:6294167|PMID:16118219)		 RGD PMID:16118219 MGI:6294167 NCBI chr 1:96,180,872...96,188,592
Ensembl chr 1:96,180,887...96,188,391 		JBrowse link
G Znf750 zinc finger protein 750 acts_upstream_of_or_within ISO MGI:7470773 (PMID:37115925) RGD PMID:37115925 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200 		JBrowse link
regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000068509 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr17:11,942,344...11,942,538 JBrowse link
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of ISO MGI:1913862 (PMID:31880535) RGD PMID:31880535 NCBI chr 9:48,243,365...48,253,316
Ensembl chr 9:48,237,572...48,253,211 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of ISO MGI:2137691|MGI:2181669|MGI:6382064 (PMID:31880535) RGD PMID:31880535 NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISO
ISS		 (PMID:17303575)
GO_REF:0000024		 RGD
UniProt		 PMID:17303575 GO_REF:0000024 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Samd8 sterile alpha motif domain containing 8 involved_in ISO (PMID:19506037) RGD PMID:19506037 NCBI chr15:2,512,104...2,562,368
Ensembl chr15:2,512,105...2,515,379
Ensembl chr15:2,512,105...2,515,379 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      amide metabolic process 455
        amide biosynthetic process 145
          ceramide biosynthetic process 74
            ganglioside biosynthetic process + 17
            glycosylceramide biosynthetic process + 7
            isogloboside biosynthetic process 0
            lactosylceramide biosynthetic process 2
            negative regulation of ceramide biosynthetic process + 4
            omega-hydroxyceramide biosynthetic process 1
            positive regulation of ceramide biosynthetic process + 8
            regulation of ceramide biosynthetic process + 14
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        lipid metabolic process 1489
          cellular lipid metabolic process 1106
            membrane lipid metabolic process 213
              sphingolipid metabolic process 158
                ceramide metabolic process 111
                  ceramide biosynthetic process 74
                    ganglioside biosynthetic process + 17
                    glycosylceramide biosynthetic process + 7
                    isogloboside biosynthetic process 0
                    lactosylceramide biosynthetic process 2
                    negative regulation of ceramide biosynthetic process + 4
                    omega-hydroxyceramide biosynthetic process 1
                    positive regulation of ceramide biosynthetic process + 8
                    regulation of ceramide biosynthetic process + 14
paths to the root