ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of proteolysis
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Accession:GO:0045862 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: positive regulation of peptidolysis;   up regulation of proteolysis;   upregulation of proteolysis
 narrow_synonym: activation of proteolysis;   stimulation of proteolysis


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positive regulation of proteolysis term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Asph aspartate-beta-hydroxylase GBrowse link 5 23,495,780 23,520,672 RGD:1624291
G Aurkaip1 aurora kinase A interacting protein 1 GBrowse link 5 172,684,455 172,685,851 RGD:1600115
RGD:1624291
G Bad BCL2-associated agonist of cell death GBrowse link 1 209,617,373 209,626,292 RGD:1600115
RGD:1624291
G Bak1 BCL2-antagonist/killer 1 GBrowse link 20 5,255,954 5,264,593 RGD:1600115
RGD:1624291
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase GBrowse link 1 250,528,730 250,693,952 RGD:1600115
RGD:1624291
G Capn3 calpain 3 GBrowse link 3 106,946,878 106,998,274 RGD:1600115
RGD:1624291
G Casp8 caspase 8 GBrowse link 9 57,389,353 57,437,803 RGD:1600115
RGD:1624291
G Cln6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant GBrowse link 8 66,987,057 67,002,013 RGD:1600115
RGD:1624291
G Cyfip2 cytoplasmic FMR1 interacting protein 2 GBrowse link 10 31,321,000 31,443,480 RGD:1600115
RGD:1624291
G Ep300 E1A binding protein p300 GBrowse link 7 119,938,507 120,008,886 RGD:2289912
G Fadd Fas (TNFRSF6)-associated via death domain GBrowse link 1 205,010,363 205,012,768 RGD:1600115
RGD:1624291
G Fbxw11 F-box and WD repeat domain containing 11 GBrowse link 10 17,502,480 17,600,199 RGD:1600115
RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 GBrowse link 17 15,512,144 15,527,348 RGD:1600115
RGD:1624291
G Hdac2 histone deacetylase 2 GBrowse link 20 41,162,093 41,186,492 RGD:1624291
G Ist1 increased sodium tolerance 1 homolog (yeast) GBrowse link 19 39,554,205 39,576,343 RGD:1600115
RGD:1624291
G Mgea5 meningioma expressed antigen 5 (hyaluronidase) GBrowse link 1 250,966,386 251,000,363 RGD:2305953
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase GBrowse link X 89,721,369 89,766,218 RGD:1600115
RGD:1624291
G Perp PERP, TP53 apoptosis effector GBrowse link 1 13,976,356 13,988,803 RGD:1600115
RGD:1624291
G Plk1 polo-like kinase 1 GBrowse link 1 181,002,811 181,012,741 RGD:1624291
G Tbc1d10a TBC1 domain family, member 10a GBrowse link 14 84,810,214 84,837,928 RGD:1624291
G Trim32 tripartite motif-containing 32 GBrowse link 5 82,380,439 82,391,290 RGD:1600115
RGD:1624291
G Wfs1 Wolfram syndrome 1 (wolframin) GBrowse link 14 79,379,680 79,404,003 RGD:1600115
RGD:1624291
activation of mitotic anaphase-promoting complex activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Plk1 polo-like kinase 1 GBrowse link 1 181,002,811 181,012,741 RGD:1600115
RGD:1624291
G Pten phosphatase and tensin homolog GBrowse link 1 236,771,027 236,837,261 RGD:1600115
RGD:1624291
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adam8 ADAM metallopeptidase domain 8 GBrowse link 1 199,780,772 199,791,855 RGD:1600115
RGD:1624291
G Adam9 ADAM metallopeptidase domain 9 GBrowse link 16 71,446,498 71,526,108 RGD:1600115
RGD:1624291
G Adra2a adrenoceptor alpha 2A RGD:1600115
RGD:1624291
G Apoe apolipoprotein E GBrowse link 1 79,003,634 79,006,387 RGD:1600115
RGD:1624291
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 GBrowse link 17 47,145,567 47,188,345 RGD:1600115
RGD:1624291
G Ifng interferon gamma GBrowse link 7 57,621,756 57,625,792 RGD:1600115
RGD:1624291
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1600115
RGD:1624291
G Nrd1 nardilysin 1 GBrowse link 5 130,345,980 130,408,734 RGD:1624291
G Pacsin3 protein kinase C and casein kinase substrate in neurons 3 GBrowse link 3 75,611,040 75,619,605 RGD:1600115
RGD:1624291
G Sh3d19 SH3 domain containing 19 GBrowse link 2 178,045,383 178,083,708 RGD:1600115
RGD:1624291
G Snx33 sorting nexin 33 GBrowse link 8 60,663,024 60,673,400 RGD:1624291
G Snx9 sorting nexin 9 RGD:1624291
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:1600115
RGD:1624291
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b GBrowse link 5 163,666,541 163,697,484 RGD:1600115
RGD:1624291
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1600115
RGD:1624291
G Fbxw7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase GBrowse link 2 176,675,226 176,750,737 RGD:1624291
G Kcne2 potassium voltage-gated channel, Isk-related family, member 2 GBrowse link 11 32,277,711 32,290,828 RGD:1600115
RGD:1624291
G Osbpl7 oxysterol binding protein-like 7 GBrowse link 10 85,771,941 85,789,490 RGD:1600115
RGD:1624291
G Park2 parkinson protein 2, E3 ubiquitin protein ligase GBrowse link 1 43,151,265 44,374,470 RGD:1624291
G Xbp1 X-box binding protein 1 GBrowse link 14 86,151,910 86,156,975 RGD:1600115
RGD:1624291
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link 6 137,640,482 137,657,552 RGD:1600115
RGD:1624291
G Aurka aurora kinase A GBrowse link 3 163,270,479 163,284,506 RGD:1600115
RGD:1624291
G Axin1 axin 1 GBrowse link 10 15,409,373 15,462,726 RGD:1600115
RGD:1624291
G Bbs7 Bardet-Biedl syndrome 7 GBrowse link 2 123,070,273 123,109,862 RGD:1600115
RGD:1624291
G Clu clusterin GBrowse link 15 45,365,779 45,405,314 RGD:1600115
RGD:1624291
G Csnk1d casein kinase 1, delta GBrowse link 10 110,166,244 110,197,233 RGD:1600115
RGD:1624291
G Csnk1e casein kinase 1, epsilon GBrowse link 7 117,402,718 117,420,764 RGD:1600115
RGD:1624291
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link 2 55,714,874 55,736,370 RGD:1600115
RGD:1624291
G Dnajb2 DnaJ (Hsp40) homolog, subfamily B, member 2 GBrowse link 9 74,517,647 74,525,857 RGD:1600115
RGD:1624291
G Dvl1 dishevelled segment polarity protein 1 GBrowse link 5 172,705,951 172,717,626 RGD:1600115
RGD:1624291
G Fbxo22 F-box protein 22 GBrowse link 8 58,751,584 58,767,613 RGD:1600115
RGD:1624291
G Gclc glutamate-cysteine ligase, catalytic subunit GBrowse link 8 82,724,429 82,762,848 RGD:1600115
RGD:1624291
G Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 GBrowse link 10 34,067,237 34,072,593 RGD:1600115
RGD:1624291
G Gsk3b glycogen synthase kinase 3 beta GBrowse link 11 64,284,731 64,428,698 RGD:1600115
RGD:1624291
G Hspbp1 HSPA binding protein, cytoplasmic cochaperone 1 GBrowse link 1 67,882,356 67,905,766 RGD:1600115
RGD:1624291
G Il33 interleukin 33 GBrowse link 1 233,670,801 233,685,798 RGD:1624291
G LOC100911959 ubiquitin carboxyl-terminal hydrolase 5-like RGD:1600115
RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 GBrowse link 7 130,105,902 130,267,747 RGD:1600115
RGD:1624291
G Mdm2 MDM2 proto-oncogene, E3 ubiquitin protein ligase GBrowse link 7 56,996,694 57,020,926 RGD:1600115
RGD:1624291
G Nkd2 naked cuticle homolog 2 (Drosophila) GBrowse link 1 30,252,093 30,278,933 RGD:1600115
RGD:1624291
G Nub1 negative regulator of ubiquitin-like proteins 1 GBrowse link 4 5,820,488 5,850,809 RGD:1600115
RGD:1624291
G Pias1 protein inhibitor of activated STAT, 1 GBrowse link 8 67,025,248 67,123,016 RGD:1600115
RGD:1624291
G Plk1 polo-like kinase 1 GBrowse link 1 181,002,811 181,012,741 RGD:1600115
RGD:1624291
G Plk2 polo-like kinase 2 GBrowse link 2 41,800,745 41,806,503 RGD:7241135
G Prickle1 prickle homolog 1 (Drosophila) GBrowse link 7 131,967,220 131,986,187 RGD:1600115
RGD:1624291
G Psen1 presenilin 1 GBrowse link 6 107,737,543 107,776,357 RGD:1600115
RGD:1624291
G Psen2 presenilin 2 GBrowse link 13 95,934,674 95,951,836 RGD:1624291
G Psmd10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 RGD:1600115
RGD:1624291
G Rchy1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase GBrowse link 14 17,683,377 17,698,982 RGD:1600115
RGD:1624291
G Rfwd2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase GBrowse link 13 74,552,876 74,590,608 RGD:1624291
G Rnf180 ring finger protein 180 GBrowse link 2 36,186,010 36,253,660 RGD:1600115
RGD:1624291
G Sirt2 sirtuin 2 GBrowse link 1 83,873,578 83,896,121 RGD:1600115
RGD:1624291
G Smad7 SMAD family member 7 GBrowse link 18 72,294,803 72,323,354 RGD:1600115
RGD:1624291
G Socs4 suppressor of cytokine signaling 4 GBrowse link 15 23,229,083 23,243,568 RGD:1600115
G Socs5 suppressor of cytokine signaling 5 GBrowse link 6 10,552,177 10,582,783 RGD:1600115
RGD:1624291
G Stub1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase GBrowse link 10 15,096,150 15,098,431 RGD:1600115
RGD:1624291
G Sumo1 small ubiquitin-like modifier 1 GBrowse link 9 58,212,538 58,242,760 RGD:1600115
RGD:1624291
G Sumo2 small ubiquitin-like modifier 2 GBrowse link 10 105,608,097 105,620,455 RGD:1624291
G Taf1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor GBrowse link X 89,590,556 89,666,569 RGD:1624291
G Trib1 tribbles pseudokinase 1 GBrowse link 7 96,442,239 96,448,785 RGD:1600115
RGD:1624291
G Trib2 tribbles pseudokinase 2 GBrowse link 6 39,474,243 39,496,718 RGD:1600115
RGD:1624291
G Ube2v2 ubiquitin-conjugating enzyme E2 variant 2 GBrowse link 11 87,215,842 87,249,726 RGD:1299567
G Usp5 ubiquitin specific peptidase 5 (isopeptidase T) GBrowse link 4 160,937,706 160,952,769 RGD:1600115
G Vcp valosin-containing protein GBrowse link 5 59,472,100 59,491,508 RGD:1599730
RGD:1624291
G Zfand2a zinc finger, AN1-type domain 2A GBrowse link 12 15,661,609 15,672,672 RGD:1600115
RGD:1624291
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Plk3 polo-like kinase 3 GBrowse link 5 137,443,540 137,448,715 RGD:1600115
RGD:1624291
G Sirt2 sirtuin 2 GBrowse link 1 83,873,578 83,896,121 RGD:1600115
RGD:1624291
positive regulation of proteolysis involved in cellular protein catabolic process term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ctsc cathepsin C GBrowse link 1 144,629,802 144,661,183 RGD:8661625

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Term Annotations click to browse term
  biological_process 178291
    biological regulation 74501
      regulation of biological process 68652
        regulation of cellular process 57834
          regulation of cellular metabolic process 19271
            regulation of cellular protein metabolic process 4098
              positive regulation of cellular protein metabolic process 2375
                positive regulation of proteolysis 176
                  positive regulation of membrane protein ectodomain proteolysis 31
                  positive regulation of proteolysis involved in cellular protein catabolic process + 105
Path 2
Term Annotations click to browse term
  biological_process 178291
    biological regulation 74501
      regulation of biological process 68652
        regulation of metabolic process 23362
          regulation of macromolecule metabolic process 18563
            regulation of gene expression 12530
              regulation of protein maturation 372
                regulation of protein processing 372
                  positive regulation of protein processing 204
                    positive regulation of proteolysis 176
                      positive regulation of membrane protein ectodomain proteolysis 31
                      positive regulation of proteolysis involved in cellular protein catabolic process + 105
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