negative regulation of isotype switching - Ontology Report

Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	negative regulation of isotype switching	go back to main search page
Accession:	GO:0045829	browse the term
Definition:	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.
Synonyms:	exact_synonym:	down regulation of isotype switching; downregulation of isotype switching; negative regulation of class switch recombination; negative regulation of class switching; negative regulation of isotype switch recombination
	narrow_synonym:	inhibition of isotype switching

negative regulation of isotype switching to IgE isotypes
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bcl6	B-cell CLL/lymphoma 6		ISO	11	79,006,123	79,030,555	RGD:1624291	RGD
G	Bcl6	B-cell CLL/lymphoma 6		IEA	11	79,006,123	79,030,555	RGD:1600115	ENSEMBL
G	Foxp3	forkhead box P3		ISO	X	26,950,006	26,965,329	RGD:1624291	RGD
G	Foxp3	forkhead box P3		IBA	X	26,950,006	26,965,329	RGD:1600115	RefGenome
G	Ndfip1	Nedd4 family interacting protein 1		ISO	18	31,351,538	31,401,736	RGD:1624291	RGD
G	Ndfip1	Nedd4 family interacting protein 1		IEA	18	31,351,538	31,401,736	RGD:1600115	ENSEMBL

Term paths to the root

Path 1
Term	Annotations
biological_process	135967
negative regulation of biological process	13304
negative regulation of immune system process	499
negative regulation of immune effector process	127
negative regulation of isotype switching	6
negative regulation of isotype switching to IgA isotypes	0
negative regulation of isotype switching to IgD isotypes	0
negative regulation of isotype switching to IgE isotypes	6
negative regulation of isotype switching to IgG isotypes	0
Path 2
Term	Annotations
biological_process	135967
metabolic process	36390
cellular metabolic process	30423
cellular aromatic compound metabolic process	15057
nucleobase-containing compound metabolic process	14436
nucleic acid metabolic process	12471
DNA metabolic process	2273
DNA recombination	365
somatic cell DNA recombination	135
somatic diversification of immune receptors via germline recombination within a single locus	134
somatic recombination of immunoglobulin gene segments	99
somatic recombination of immunoglobulin genes involved in immune response	78
isotype switching	76
regulation of isotype switching	41
negative regulation of isotype switching	6
negative regulation of isotype switching to IgA isotypes	0
negative regulation of isotype switching to IgD isotypes	0
negative regulation of isotype switching to IgE isotypes	6
negative regulation of isotype switching to IgG isotypes	0