insulin receptor substrate binding - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	insulin receptor substrate binding	go back to main search page
Accession:	GO:0043560	browse the term
Definition:	Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
Synonyms:	exact_synonym:	IRS [protein] binding; IRS binding; insulin receptor substrate [protein] binding

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insulin receptor substrate binding
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Grb2	growth factor receptor bound protein 2		IPI	10	105,722,014	105,818,649	RGD:1299201	RGD
G	Grb2	growth factor receptor bound protein 2		IPI	10	105,722,014	105,818,649	RGD:1299201	RGD
G	Grb2	growth factor receptor bound protein 2		ISO	10	105,722,014	105,818,649	RGD:1624291	RGD
G	Igf1r	insulin-like growth factor 1 receptor		IPI	1	122,704,976	122,990,007	RGD:1581313	RGD
G	Igf1r	insulin-like growth factor 1 receptor		ISO	1	122,704,976	122,990,007	RGD:1624291	RGD
G	Igf1r	insulin-like growth factor 1 receptor		ISS	1	122,704,976	122,990,007	RGD:1600115	UniProtKB
G	Insr	insulin receptor		IMP	12	2,934,967	3,087,691	RGD:1580595	RGD
G	Insr	insulin receptor		ISO	12	2,934,967	3,087,691	RGD:1624291	RGD
G	Insr	insulin receptor		ISO	12	2,934,967	3,087,691	RGD:1624291	RGD
G	Insr	insulin receptor		IEA	12	2,934,967	3,087,691	RGD:1600115	InterPro
G	Insr	insulin receptor		IEA	12	2,934,967	3,087,691	RGD:1600115	ENSEMBL
G	Insr	insulin receptor		ISO	12	2,934,967	3,087,691	RGD:1624291	RGD
G	Insrr	insulin receptor-related receptor		IEA	2	179,857,189	179,876,572	RGD:1600115	InterPro
G	Jak2	Janus kinase 2		IPI	1	232,915,995	232,974,763	RGD:1641881	RGD
G	Pik3ca	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha		ISO	2	118,640,277	118,672,440	RGD:1624291	RGD
G	Pik3cb	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta		ISO	8	103,886,682	103,957,112	RGD:1624291	RGD
G	Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)		IPI	2	32,602,673	32,675,350	RGD:1299201	RGD
G	Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)		IPI	2	32,602,673	32,675,350	RGD:1299201	RGD
G	Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)		ISO	2	32,602,673	32,675,350	RGD:1624291	RGD
G	Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)		ISS	2	32,602,673	32,675,350	RGD:1600115	UniProtKB
G	Pik3r1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)		IPI	2	32,602,673	32,675,350		BHF-UCL
G	Prkcd	protein kinase C, delta		ISO	16	5,954,218	5,975,743	RGD:1624291	RGD
G	Prkcd	protein kinase C, delta		IEA	16	5,954,218	5,975,743	RGD:1600115	ENSEMBL
G	Ptpn11	protein tyrosine phosphatase, non-receptor type 11		IPI	12	36,501,886	36,558,055	RGD:1299201	RGD
G	Wdr6	WD repeat domain 6		IPI	8	113,618,341	113,624,757	RGD:2301084	RGD

Term paths to the root

Path 1
Term	Annotations
molecular_function	87625
binding	56359
protein binding	38746
insulin receptor substrate binding	25