ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of MAPK cascade
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Accession:GO:0043410 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
Synonyms:exact_synonym: positive regulation of MAP kinase cascade;   positive regulation of MAPKKK cascade;   positive regulation of mitogen-activated protein kinase cascade;   stimulation of MAPK cascade;   up regulation of MAPKKK cascade;   up-regulation of MAPK cascade;   upregulation of MAPK cascade;   upregulation of MAPKKK cascade
 narrow_synonym: activation of MAPK cascade;   activation of MAPKKK cascade;   stimulation of MAPKKK cascade


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positive regulation of MAPK cascade term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A GBrowse link 15 46,173,429 46,263,198 RGD:1600115
RGD:1624291
G Adra1b adrenoceptor alpha 1B GBrowse link 10 28,889,092 28,946,889 RGD:1600115
RGD:1624291
G Adrb2 adrenoceptor beta 2, surface GBrowse link 18 58,174,958 58,177,000 RGD:1600115
RGD:1624291
G Adrb3 adrenoceptor beta 3 GBrowse link 16 69,163,620 69,166,384 RGD:1600115
RGD:1624291
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) GBrowse link 19 54,738,556 54,750,349 RGD:1600115
RGD:1624291
G Alox12b arachidonate 12-lipoxygenase, 12R type GBrowse link 10 55,917,373 55,926,321 RGD:1600115
RGD:1624291
G Ar androgen receptor GBrowse link X 85,949,507 86,119,199 RGD:1600115
RGD:1624291
G Bank1 B-cell scaffold protein with ankyrin repeats 1 GBrowse link 2 233,471,600 233,747,012 RGD:1624291
G Bmp2 bone morphogenetic protein 2 GBrowse link 3 121,372,692 121,381,236 RGD:1624291
G Bnip2 BCL2/adenovirus E1B interacting protein 2 GBrowse link 8 74,421,904 74,435,300 RGD:1600115
RGD:1624291
G C1qtnf1 C1q and tumor necrosis factor related protein 1 GBrowse link 10 108,431,984 108,452,099 RGD:1600115
RGD:1624291
G Ccr2 chemokine (C-C motif) receptor 2 GBrowse link 8 128,892,784 128,893,905 RGD:2303073
G Cd36 CD36 molecule (thrombospondin receptor) GBrowse link 4 13,471,878 13,525,620 RGD:1624291
G Cdc42 cell division cycle 42 GBrowse link 5 156,106,123 156,143,040 RGD:1624291
G Cdh2 cadherin 2 GBrowse link 18 8,048,920 8,267,974 RGD:1600115
RGD:1624291
G Cdk10 cyclin-dependent kinase 10 GBrowse link 19 53,545,204 53,552,911 RGD:1624291
G Cdon cell adhesion associated, oncogene regulated GBrowse link 8 35,238,899 35,291,743 RGD:1600115
RGD:1624291
G Cntf ciliary neurotrophic factor GBrowse link 1 215,842,668 215,844,691 RGD:1626128
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link 8 125,978,161 125,987,670 RGD:1600115
RGD:1624291
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1600115
RGD:1624291
G Dusp19 dual specificity phosphatase 19 GBrowse link 3 63,473,333 63,485,843 RGD:1624291
G Epha8 Eph receptor A8 GBrowse link 5 155,696,393 155,717,598 RGD:1600115
RGD:1624291
G Erbb2 v-erb-b2 avian erythroblastic leukemia viral oncogene 2 GBrowse link 10 87,219,157 87,242,919 RGD:1582137
G F2r coagulation factor II (thrombin) receptor GBrowse link 2 25,985,800 25,989,072 RGD:1600115
RGD:1624291
G Fam58b family with sequence similarity 58, member B GBrowse link 10 64,864,942 64,866,105 RGD:1624291
G Fgf10 fibroblast growth factor 10 GBrowse link 2 50,866,799 50,940,319 RGD:1624291
G Fgf9 fibroblast growth factor 9 GBrowse link 15 37,115,068 37,155,652 RGD:8553955
G Fgfr1 Fibroblast growth factor receptor 1 GBrowse link 16 70,869,974 70,910,045 RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 GBrowse link 1 189,482,975 189,589,279 RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 GBrowse link 14 82,683,191 82,697,229 RGD:1624291
G Flt1 FMS-related tyrosine kinase 1 GBrowse link 12 7,858,092 8,035,966 RGD:1624291
G Flt4 fms-related tyrosine kinase 4 GBrowse link 10 35,071,002 35,112,006 RGD:1624291
G Gab1 GRB2-associated binding protein 1 GBrowse link 19 28,980,284 29,088,877 RGD:1624291
G Gper1 G protein-coupled estrogen receptor 1 GBrowse link 12 15,718,615 15,719,893 RGD:1600115
RGD:1624291
G Grm4 glutamate receptor, metabotropic 4 GBrowse link 20 5,627,733 5,727,274 RGD:1624291
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1624291
G Igf1 insulin-like growth factor 1 GBrowse link 7 24,531,669 24,605,742 RGD:1600115
RGD:1624291
G Igf1r insulin-like growth factor 1 receptor GBrowse link 1 122,704,976 122,990,007 RGD:1600115
RGD:1624291
G Igf2 insulin-like growth factor 2 GBrowse link 1 202,906,624 202,915,231 RGD:1600115
RGD:1624291
G Igfbp3 insulin-like growth factor binding protein 3 GBrowse link 14 87,959,153 87,967,085 RGD:1600115
RGD:1624291
G Igfbp4 insulin-like growth factor binding protein 4 GBrowse link 10 87,822,429 87,834,315 RGD:1600115
RGD:1624291
G Il11 interleukin 11 GBrowse link 1 67,784,584 67,795,141 RGD:1600115
RGD:1624291
G Il6 interleukin 6 GBrowse link 4 456,799 461,376 RGD:1624291
G Il6r interleukin 6 receptor GBrowse link 2 182,078,049 182,128,135 RGD:1600115
RGD:1624291
G Ilk integrin-linked kinase GBrowse link 1 163,481,299 163,487,550 RGD:2302063
G Ins2 insulin 2 GBrowse link 1 202,935,548 202,936,379 RGD:1624291
G Insr insulin receptor GBrowse link 12 2,934,967 3,087,691 RGD:1624291
G Itgav integrin, alpha V GBrowse link 3 66,953,403 67,029,774 RGD:1625134
G Itgb1 integrin, beta 1 GBrowse link 19 58,600,095 58,647,531 RGD:1625134
G Itgb3 integrin, beta 3 RGD:1625134
G Kdr kinase insert domain receptor RGD:1600115
RGD:1624291
G Kiss1 KiSS-1 metastasis-suppressor GBrowse link 13 46,244,786 46,247,288 RGD:1599289
G Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link 14 34,906,043 34,984,819 RGD:1624291
G Kng1 kininogen 1 GBrowse link 11 80,109,499 80,131,887 RGD:1600455
G Ksr1 kinase suppressor of ras 1 GBrowse link 10 65,186,444 65,322,155 RGD:1600115
RGD:1624291
G Ksr2 kinase suppressor of ras 2 GBrowse link 12 39,998,030 40,376,125 RGD:1624291
G Lamtor1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 GBrowse link 1 159,367,471 159,373,042 RGD:1600115
RGD:1624291
G Lep leptin GBrowse link 4 55,943,837 55,945,938 RGD:2290294
G Lepr leptin receptor GBrowse link 5 122,320,075 122,503,449 RGD:2290294
G Lepr_v1 leptin receptor, variant 1 RGD:2290294
G Lepr_v2 leptin receptor, variant 2 RGD:2290294
G Lif leukemia inhibitory factor GBrowse link 14 84,887,856 84,890,630 RGD:1600115
RGD:1624291
G Lpar1 lysophosphatidic acid receptor 1 GBrowse link 5 76,449,470 76,571,458 RGD:1624291
G Lpar2 lysophosphatidic acid receptor 2 GBrowse link 16 20,079,826 20,085,307 RGD:1624291
G Lpar3 lysophosphatidic acid receptor 3 GBrowse link 2 244,431,789 244,510,815 RGD:1624291
G Nenf neudesin neurotrophic factor GBrowse link 13 107,368,359 107,377,301 RGD:1600115
RGD:1624291
G Ngfr nerve growth factor receptor GBrowse link 10 84,262,804 84,281,006 RGD:5508773
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link 19 19,662,337 19,697,341 RGD:1624291
G Nox1 NADPH oxidase 1 RGD:1624291
G Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 GBrowse link 17 11,494,463 11,811,654 RGD:8553408
G Osm oncostatin M GBrowse link 14 84,857,232 84,860,082 RGD:1600115
RGD:1624291
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 GBrowse link 12 35,074,025 35,117,152 RGD:1624291
G Pdgfa platelet-derived growth factor alpha polypeptide GBrowse link 12 16,151,045 16,172,412 RGD:1600115
RGD:1624291
G Pdgfb platelet-derived growth factor beta polypeptide GBrowse link 7 118,244,385 118,262,021 RGD:1600115
RGD:1624291
G Peli2 pellino E3 ubiquitin protein ligase family member 2 GBrowse link 15 24,227,734 24,371,242 RGD:1600115
RGD:1624291
G Prkcd protein kinase C, delta GBrowse link 16 5,954,218 5,975,743 RGD:1642529
G Prkce protein kinase C, epsilon GBrowse link 6 9,631,234 10,097,311 RGD:1600115
RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C GBrowse link 13 51,246,163 51,357,995 RGD:1624291
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 GBrowse link 17 37,183,591 37,216,533 RGD:1624291
G Ryk receptor-like tyrosine kinase GBrowse link 8 107,822,823 107,894,331 RGD:1600115
RGD:1624291
G Sorbs3 sorbin and SH3 domain containing 3 GBrowse link 15 50,580,018 50,611,107 RGD:1600115
RGD:1624291
G Sox2 SRY (sex determining region Y)-box 2 GBrowse link 2 120,969,021 120,971,430 RGD:1600115
RGD:1624291
G Spag9 sperm associated antigen 9 GBrowse link 10 82,649,289 82,762,795 RGD:1624291
G Sstr4 somatostatin receptor 4 GBrowse link 3 137,150,419 137,152,284 RGD:2325010
G Tbx1 T-box 1 GBrowse link 11 84,400,980 84,410,631 RGD:1600115
RGD:1624291
G Timp2 TIMP metallopeptidase inhibitor 2 GBrowse link 10 108,310,473 108,358,821 RGD:1598578
G Traf7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase GBrowse link 10 13,760,687 13,779,228 RGD:1600115
RGD:1624291
G Trim5 tripartite motif-containing 5 GBrowse link 1 162,096,439 162,113,409 RGD:1624291
G Wwc1 WW and C2 domain containing 1 GBrowse link 10 20,750,770 20,910,298 RGD:1600115
RGD:1624291
G Zfp622 zinc finger protein 622 GBrowse link 2 77,571,866 77,585,706 RGD:1624291
activation of JUN kinase activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Axin1 axin 1 GBrowse link 10 15,409,373 15,462,726 RGD:1600115
G Crk v-crk avian sarcoma virus CT10 oncogene homolog GBrowse link 10 63,017,662 63,040,420 RGD:1298803
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link 2 55,714,874 55,736,370 RGD:1600115
RGD:1624291
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1600115
RGD:1624291
G Ercc6 excision repair cross-complementation group 6 GBrowse link 16 8,024,881 8,091,587 RGD:1600115
RGD:1624291
G Fcer1a Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide GBrowse link 13 89,429,982 89,436,507 RGD:1600115
RGD:1624291
G Fgd4 FYVE, RhoGEF and PH domain containing 4 GBrowse link 11 86,700,118 86,767,928 RGD:1299389
G Gab1 GRB2-associated binding protein 1 GBrowse link 19 28,980,284 29,088,877 RGD:1600115
RGD:1624291
G Ins2 insulin 2 GBrowse link 1 202,935,548 202,936,379 RGD:1624291
G Map2k4 mitogen activated protein kinase kinase 4 GBrowse link 10 52,009,149 52,041,599 RGD:2298577
RGD:2298708
G Map2k7 mitogen activated protein kinase kinase 7 GBrowse link 12 1,545,407 1,552,353 RGD:1624291
RGD:2298561
RGD:2298565
RGD:2298577
G Map3k1 mitogen activated protein kinase kinase kinase 1 GBrowse link 2 43,062,252 43,126,058 RGD:1624291
G Map3k11 mitogen-activated protein kinase kinase kinase 11 GBrowse link 1 208,312,955 208,326,289 RGD:1600115
RGD:1624291
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 GBrowse link 1 209,121,164 209,136,316 RGD:1600115
RGD:1624291
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link 10 14,147,895 14,186,277 RGD:1600115
RGD:1624291
G Mdfi MyoD family inhibitor GBrowse link 9 8,623,038 8,641,388 RGD:1600115
RGD:1624291
G Mdfic MyoD family inhibitor domain containing GBrowse link 4 41,241,856 41,321,515 RGD:1600115
RGD:1624291
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 GBrowse link 5 157,213,350 157,222,401 RGD:1600115
RGD:1624291
G Spag9 sperm associated antigen 9 GBrowse link 10 82,649,289 82,762,795 RGD:1600115
RGD:1624291
G Syk spleen tyrosine kinase GBrowse link 17 18,440,672 18,498,001 RGD:1600115
RGD:1624291
G Tf transferrin GBrowse link 8 108,217,774 108,244,487 RGD:1624291
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link 15 59,397,837 59,428,014 RGD:1624291
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link 16 3,782,025 3,799,625 RGD:1600115
RGD:1624291
G Wnt7b wingless-type MMTV integration site family, member 7B GBrowse link 7 123,533,713 123,554,333 RGD:2292645
G Zak sterile alpha motif and leucine zipper containing kinase AZK GBrowse link 3 54,767,724 54,915,022 RGD:1600115
RGD:1624291
activation of MAPK activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra2b adrenoceptor alpha 2B GBrowse link 3 114,867,357 114,869,680 RGD:1304238
G Alk anaplastic lymphoma receptor tyrosine kinase GBrowse link 6 23,009,061 23,730,939 RGD:1600115
G Arrb1 arrestin, beta 1 GBrowse link 1 156,871,564 156,937,540 RGD:631797
RGD:1304268
G Avpi1 arginine vasopressin-induced 1 GBrowse link 1 248,727,385 248,733,112 RGD:1600115
RGD:1624291
G Bmp2 bone morphogenetic protein 2 GBrowse link 3 121,372,692 121,381,236 RGD:1600115
RGD:1624291
G C1qtnf2 C1q and tumor necrosis factor related protein 2 GBrowse link 10 28,571,051 28,588,714 RGD:1600115
RGD:1624291
G Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain GBrowse link 18 56,756,511 56,765,711 RGD:728220
G Cd81 Cd81 molecule GBrowse link 1 203,327,287 203,342,901 RGD:1600115
RGD:1624291
G Chrna7 cholinergic receptor, nicotinic, alpha 7 (neuronal) GBrowse link 1 117,587,580 117,716,267 RGD:1600115
RGD:1624291
G Cspg4 chondroitin sulfate proteoglycan 4 GBrowse link 8 60,610,835 60,645,877 RGD:1600115
RGD:1624291
G Drd4 dopamine receptor D4 GBrowse link 1 201,485,597 201,488,784 RGD:1600115
RGD:1624291
G Efna1 ephrin A1 GBrowse link 2 181,444,599 181,451,944 RGD:1600115
RGD:1624291
G Epgn epithelial mitogen GBrowse link 14 18,573,036 18,579,934 RGD:1600115
RGD:1624291
G Fcer1a Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide GBrowse link 13 89,429,982 89,436,507 RGD:1624291
G Fgf10 fibroblast growth factor 10 GBrowse link 2 50,866,799 50,940,319 RGD:1600115
RGD:1624291
G Frs2 fibroblast growth factor receptor substrate 2 GBrowse link 7 56,409,863 56,490,535 RGD:1600115
RGD:1624291
G Gab1 GRB2-associated binding protein 1 GBrowse link 19 28,980,284 29,088,877 RGD:1624291
G Ghr growth hormone receptor GBrowse link 2 52,496,517 52,658,066 RGD:8553732
G Ghrl ghrelin/obestatin prepropeptide GBrowse link 4 149,622,566 149,628,111 RGD:1600115
RGD:1624291
G Grm1 glutamate receptor, metabotropic 1 GBrowse link 1 5,318,617 5,744,593 RGD:1600115
RGD:1624291
G Grm4 glutamate receptor, metabotropic 4 GBrowse link 20 5,627,733 5,727,274 RGD:1600115
RGD:1624291
G Hgf hepatocyte growth factor GBrowse link 4 14,864,357 14,932,513 RGD:1600115
RGD:1624291
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1600115
RGD:1624291
G Ins2 insulin 2 GBrowse link 1 202,935,548 202,936,379 RGD:1600115
RGD:1624291
G Insr insulin receptor GBrowse link 12 2,934,967 3,087,691 RGD:1600115
RGD:1624291
G Iqgap3 IQ motif containing GTPase activating protein 3 GBrowse link 2 180,155,679 180,198,814 RGD:1600115
RGD:1624291
G Itga1 integrin, alpha 1 GBrowse link 2 47,107,849 47,206,261 RGD:2302385
G Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link 14 34,906,043 34,984,819 RGD:1600115
RGD:1624291
G Lpar1 lysophosphatidic acid receptor 1 GBrowse link 5 76,449,470 76,571,458 RGD:1600115
RGD:1624291
G Lpar2 lysophosphatidic acid receptor 2 GBrowse link 16 20,079,826 20,085,307 RGD:1600115
RGD:1624291
G Lpar3 lysophosphatidic acid receptor 3 GBrowse link 2 244,431,789 244,510,815 RGD:1600115
RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 GBrowse link 7 130,105,902 130,267,747 RGD:1600115
RGD:1624291
G Madd MAP-kinase activating death domain GBrowse link 3 75,498,321 75,541,073 RGD:1600115
RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 GBrowse link 8 68,379,074 68,451,554 RGD:1624291
RGD:2293305
RGD:8553538
G Map2k2 mitogen activated protein kinase kinase 2 GBrowse link 7 10,074,654 10,094,003 RGD:8553538
G Map2k3 mitogen activated protein kinase kinase 3 GBrowse link 10 47,075,270 47,096,617 RGD:1624291
G Map2k5 mitogen activated protein kinase kinase 5 GBrowse link 8 67,313,472 67,542,723 RGD:8553940
G Map2k6 mitogen-activated protein kinase kinase 6 GBrowse link 10 99,859,684 99,974,446 RGD:1600115
RGD:1624291
G Map3k11 mitogen-activated protein kinase kinase kinase 11 GBrowse link 1 208,312,955 208,326,289 RGD:1624291
G Map3k2 mitogen activated protein kinase kinase kinase 2 GBrowse link 18 24,606,219 24,672,732 RGD:724475
G Map3k5 mitogen-activated protein kinase kinase kinase 5 GBrowse link 1 15,205,361 15,346,422 RGD:1600115
RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 GBrowse link 5 48,252,637 48,308,820 RGD:1624291
G Met MET proto-oncogene, receptor tyrosine kinase GBrowse link 4 43,134,183 43,211,355 RGD:1600115
RGD:1624291
G Mos Moloney sarcoma oncogene GBrowse link 5 17,158,906 17,160,204 RGD:1600115
G Muc20 mucin 20, cell surface associated GBrowse link 11 69,808,275 69,823,526 RGD:1600115
RGD:1624291
G Ntf3 neurotrophin 3 GBrowse link 4 162,435,781 162,506,961 RGD:1600115
RGD:1624291
G Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 GBrowse link 1 133,925,530 134,302,139 RGD:1600115
RGD:1624291
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 GBrowse link 12 35,074,025 35,117,152 RGD:1600115
RGD:1624291
G Pak3 p21 protein (Cdc42/Rac)-activated kinase 3 GBrowse link X 34,734,814 34,842,093 RGD:1600115
RGD:1624291
G Pde6g phosphodiesterase 6G, cGMP-specific, rod, gamma RGD:1600115
RGD:1624291
G Pde6h phosphodiesterase 6H, cGMP-specific, cone, gamma GBrowse link 4 174,009,860 174,014,405 RGD:1600115
RGD:1624291
G Plce1 phospholipase C, epsilon 1 GBrowse link 1 242,794,858 243,103,437 RGD:1600115
RGD:1624291
G Prdx2 peroxiredoxin 2 GBrowse link 19 24,836,199 24,841,390 RGD:1624291
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link 2 54,327,821 54,360,462 RGD:1600115
G Prok1 prokineticin 1 GBrowse link 2 202,707,628 202,712,886 RGD:1600115
RGD:1624291
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link 12 36,501,886 36,558,055 RGD:1600115
RGD:1624291
G Ptprc protein tyrosine phosphatase, receptor type, C GBrowse link 13 51,246,163 51,357,995 RGD:1600115
RGD:1624291
G Pxn paxillin GBrowse link 12 42,322,193 42,370,507 RGD:1600115
RGD:1624291
G Shc1 SHC (Src homology 2 domain containing) transforming protein 1 GBrowse link 2 181,616,581 181,628,144 RGD:1580336
RGD:1600115
RGD:1624291
G Sod1 superoxide dismutase 1, soluble GBrowse link 11 29,810,766 29,816,342 RGD:1600115
RGD:1624291
G Spag9 sperm associated antigen 9 GBrowse link 10 82,649,289 82,762,795 RGD:1624291
G Syk spleen tyrosine kinase GBrowse link 17 18,440,672 18,498,001 RGD:1624291
G Tdgf1 teratocarcinoma-derived growth factor 1 GBrowse link 8 115,341,587 115,346,871 RGD:1600115
RGD:1624291
G Tgfa transforming growth factor alpha GBrowse link 4 120,355,649 120,437,772 RGD:1600115
RGD:1624291
G Tgfb3 transforming growth factor, beta 3 GBrowse link 6 110,173,443 110,195,215 RGD:1579859
G Thbs1 thrombospondin 1 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 GBrowse link 5 83,564,100 83,577,735 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:1600115
RGD:1624291
G Tp73 tumor protein p73 GBrowse link 5 170,848,979 171,078,739 RGD:2291838
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link 16 3,782,025 3,799,625 RGD:1624291
activation of MAPK activity by adrenergic receptor signaling pathway term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A RGD:1600115
RGD:1624291
G Adra2b adrenoceptor alpha 2B GBrowse link 3 114,867,357 114,869,680 RGD:1600115
RGD:1624291
G Adra2c adrenoceptor alpha 2C GBrowse link 14 81,107,907 81,109,610 RGD:1600115
RGD:1624291
activation of MAPK activity involved in innate immune response term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adam8 ADAM metallopeptidase domain 8 GBrowse link 1 199,780,772 199,791,855 RGD:1600115
RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link 19 19,662,337 19,697,341 RGD:1624291
positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Abca7 ATP-binding cassette, subfamily A (ABC1), member 7 GBrowse link 7 11,203,983 11,222,960 RGD:1600115
G Adcyap1 adenylate cyclase activating polypeptide 1 RGD:1624291
RGD:8554519
G Adra1a adrenoceptor alpha 1A GBrowse link 15 46,173,429 46,263,198 RGD:5688340
G Alox15 arachidonate 15-lipoxygenase GBrowse link 10 57,185,939 57,194,388 RGD:1600115
RGD:1624291
G Angpt1 angiopoietin 1 GBrowse link 7 78,195,504 78,451,471 RGD:1600115
RGD:1624291
G Arhgap8 Rho GTPase activating protein 8 GBrowse link 7 122,730,224 122,794,430 RGD:1624291
G Arrb1 arrestin, beta 1 GBrowse link 1 156,871,564 156,937,540 RGD:1624291
RGD:5509998
G Arrb2 arrestin, beta 2 GBrowse link 10 57,244,071 57,284,166 RGD:1624291
RGD:5510006
G Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 GBrowse link X 160,306,354 160,313,434 RGD:1600115
G Bmp2 bone morphogenetic protein 2 GBrowse link 3 121,372,692 121,381,236 RGD:1600115
RGD:1624291
G Bmp4 bone morphogenetic protein 4 GBrowse link 15 22,283,171 22,286,757 RGD:1600115
RGD:1624291
G Bmper BMP-binding endothelial regulator GBrowse link 8 22,975,570 23,096,066 RGD:1600115
RGD:1624291
G Braf B-Raf proto-oncogene, serine/threonine kinase GBrowse link 4 67,117,759 67,243,058 RGD:1624291
RGD:2315869
G C1qtnf3 C1q and tumor necrosis factor related protein 3 GBrowse link 2 60,303,261 60,325,510 RGD:1600115
RGD:1624291
G C3 complement component 3 RGD:5129534
G C5ar1 complement component 5a receptor 1 RGD:1600115
RGD:1624291
G C5ar2 complement component 5a receptor 2 RGD:1600115
G Camk2d calcium/calmodulin-dependent protein kinase II delta GBrowse link 2 223,840,650 224,108,082 RGD:6907067
G Ccl19 chemokine (C-C motif) ligand 19 GBrowse link 5 59,221,738 59,223,682 RGD:1600115
RGD:1624291
G Ccl21 chemokine (C-C motif) ligand 21 GBrowse link 5 59,238,897 59,240,001 RGD:1600115
RGD:1624291
G Ccl3 chemokine (C-C motif) ligand 3 GBrowse link 10 71,744,559 71,746,109 RGD:1600115
RGD:1624291
G Ccr1 chemokine (C-C motif) receptor 1 GBrowse link 8 128,693,658 128,699,213 RGD:1624291
G Cd44 Cd44 molecule GBrowse link 3 88,022,962 88,110,352 RGD:1600115
RGD:1624291
G Cd74 Cd74 molecule, major histocompatibility complex, class II invariant chain GBrowse link 18 56,756,511 56,765,711 RGD:1600115
RGD:1624291
G Chi3l1 chitinase 3-like 1 (cartilage glycoprotein-39) GBrowse link 13 47,139,658 47,147,591 RGD:1600115
RGD:1624291
G Cib1 calcium and integrin binding 1 (calmyrin) GBrowse link 1 136,031,865 136,045,153 RGD:1600115
RGD:1624291
G Csf1r colony stimulating factor 1 receptor GBrowse link 18 57,080,324 57,107,295 RGD:1600115
RGD:1624291
G Ctgf connective tissue growth factor GBrowse link 1 21,327,099 21,330,215 RGD:1600115
RGD:1624291
G Cxcr7 chemokine (C-X-C motif) receptor 7 GBrowse link 9 89,343,528 89,355,053 RGD:1600115
RGD:1624291
G Cysltr2 cysteinyl leukotriene receptor 2 GBrowse link 15 53,647,500 53,648,429 RGD:5144006
G Dcc DCC netrin 1 receptor GBrowse link 18 68,026,795 69,140,741 RGD:2314384
G Drd2 dopamine receptor D2 GBrowse link 8 52,641,160 52,707,749 RGD:2311559
G Ednra endothelin receptor type A GBrowse link 19 32,042,366 32,108,153 RGD:4892323
G Egfr epidermal growth factor receptor GBrowse link 14 97,617,358 97,788,211 RGD:1600115
RGD:1624291
G Erbb4 v-erb-b2 avian erythroblastic leukemia viral oncogene 4 GBrowse link 9 66,843,898 67,967,970 RGD:1600115
RGD:1624291
G Esr1 estrogen receptor 1 GBrowse link 1 35,523,680 35,759,891 RGD:5128669
G Esr2 estrogen receptor 2 (ER beta) GBrowse link 6 98,691,167 98,775,299 RGD:5128669
G F2r coagulation factor II (thrombin) receptor GBrowse link 2 25,985,800 25,989,072 RGD:1600115
RGD:1624291
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link 2 25,886,177 25,899,128 RGD:1600115
RGD:1624291
G Fbxw7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase GBrowse link 2 176,675,226 176,750,737 RGD:1600115
RGD:1624291
G Ffar4 free fatty acid receptor 4 GBrowse link 1 242,423,455 242,441,475 RGD:1600115
RGD:1624291
G Fga fibrinogen alpha chain GBrowse link 2 174,737,640 174,753,598 RGD:1624291
G Fgb fibrinogen beta chain GBrowse link 2 174,768,193 174,775,102 RGD:1624291
G Fgf10 fibroblast growth factor 10 GBrowse link 2 50,866,799 50,940,319 RGD:1600115
RGD:1624291
G Fgf18 fibroblast growth factor 18 RGD:1600115
RGD:1624291
G Fgf19 fibroblast growth factor 19 GBrowse link 1 205,324,890 205,328,178 RGD:1600115
RGD:1624291
G Fgf2 fibroblast growth factor 2 GBrowse link 2 123,893,314 123,947,136 RGD:1600115
RGD:1624291
G Fgf20 fibroblast growth factor 20 GBrowse link 16 55,386,987 55,393,744 RGD:8553960
G Fgf21 fibroblast growth factor 21 GBrowse link 1 96,082,475 96,083,718 RGD:1600115
RGD:1624291
G Fgf23 fibroblast growth factor 23 GBrowse link 4 163,468,604 163,476,325 RGD:1600115
RGD:1624291
G Fgf4 fibroblast growth factor 4 GBrowse link 1 205,292,272 205,293,705 RGD:1600115
RGD:1624291
G Fgfr2 fibroblast growth factor receptor 2 GBrowse link 1 189,482,975 189,589,279 RGD:1600115
RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 GBrowse link 14 82,683,191 82,697,229 RGD:1600115
RGD:1624291
G Fgfr4 fibroblast growth factor receptor 4 GBrowse link 17 15,512,144 15,527,348 RGD:1600115
RGD:1624291
G Fgg fibrinogen gamma chain GBrowse link 2 174,727,312 174,734,594 RGD:1624291
G Flt4 fms-related tyrosine kinase 4 GBrowse link 10 35,071,002 35,112,006 RGD:1600115
RGD:1624291
G Garem GRB2 associated, regulator of MAPK1 RGD:1600115
RGD:1624291
G Gas6 growth arrest specific 6 GBrowse link 16 80,900,159 80,930,929 RGD:1600115
RGD:1624291
G Gcg glucagon GBrowse link 3 44,433,180 44,438,004 RGD:1600115
RGD:1624291
G Gcnt2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme GBrowse link 17 29,767,383 29,808,950 RGD:1624291
G Glipr2 GLI pathogenesis-related 2 GBrowse link 5 60,419,965 60,439,957 RGD:1624291
G Gper1 G protein-coupled estrogen receptor 1 GBrowse link 12 15,718,615 15,719,893 RGD:1624291
RGD:4892081
RGD:4892084
RGD:8553898
RGD:8553942
G Gpr183 G protein-coupled receptor 183 GBrowse link 15 107,056,367 107,067,887 RGD:1600115
RGD:1624291
G Gpr55 G protein-coupled receptor 55 GBrowse link 9 84,657,975 84,658,934 RGD:1600115
RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link 2 27,127,504 27,149,580 RGD:5508698
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1624291
RGD:2314843
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link 15 55,463,743 55,532,293 RGD:1600115
RGD:1624291
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link 9 84,840,026 84,852,984 RGD:1600115
RGD:1624291
G Htr2c 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled GBrowse link X 31,012,921 31,244,127 RGD:1600115
RGD:1624291
G Icam1 intercellular adhesion molecule 1 GBrowse link 8 20,040,177 20,051,939 RGD:1624291
G Il1a interleukin 1 alpha GBrowse link 3 116,913,612 116,924,114 RGD:2311095
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1358666
G Il6 interleukin 6 GBrowse link 4 456,799 461,376 RGD:2306937
RGD:5128677
G Itgb3 integrin, beta 3 RGD:4892659
G Kdr kinase insert domain receptor RGD:1600115
RGD:1624291
G Mapk3 mitogen activated protein kinase 3 GBrowse link 1 185,935,044 185,941,245 RGD:1624291
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link 20 13,191,986 13,192,851 RGD:1624291
G Mt3 metallothionein 3 GBrowse link 19 11,284,554 11,286,402 RGD:1600115
RGD:1624291
G Nod1 nucleotide-binding oligomerization domain containing 1 GBrowse link 4 83,398,809 83,449,207 RGD:1600115
RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link 19 19,662,337 19,697,341 RGD:1600115
RGD:1624291
G Nodal nodal growth differentiation factor GBrowse link 20 29,546,982 29,555,419 RGD:1600115
RGD:1624291
G Nox4 NADPH oxidase 4 GBrowse link 1 143,415,816 143,603,554 RGD:1600115
RGD:1624291
G Nrp1 neuropilin 1 GBrowse link 19 58,332,004 58,487,686 RGD:1624291
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 GBrowse link 2 179,838,740 179,855,545 RGD:1600115
RGD:1624291
G Oprm1 opioid receptor, mu 1 GBrowse link 1 37,535,416 37,779,392 RGD:8656005
G P2ry1 purinergic receptor P2Y, G-protein coupled, 1 GBrowse link 2 150,460,361 150,465,855 RGD:8554370
G Pdgfa platelet-derived growth factor alpha polypeptide GBrowse link 12 16,151,045 16,172,412 RGD:1600115
RGD:1624291
G Pdgfb platelet-derived growth factor beta polypeptide GBrowse link 7 118,244,385 118,262,021 RGD:1600115
RGD:1624291
G Pdgfra platelet derived growth factor receptor, alpha polypeptide GBrowse link 14 35,369,422 35,418,126 RGD:1600115
RGD:1624291
G Pdgfrb platelet derived growth factor receptor, beta polypeptide GBrowse link 18 57,014,475 57,053,581 RGD:1600115
RGD:1624291
G Prkca protein kinase C, alpha GBrowse link 10 97,367,196 97,638,910 RGD:8554603
G Prkcdbp protein kinase C, delta binding protein GBrowse link 1 163,212,922 163,214,511 RGD:1624291
G Prkcz protein kinase C, zeta GBrowse link 5 172,061,825 172,172,793 RGD:1600115
RGD:1624291
RGD:8554313
G Prkd2 protein kinase D2 GBrowse link 1 77,168,290 77,197,277 RGD:1600115
RGD:1624291
G Ptk2b protein tyrosine kinase 2 beta GBrowse link 15 45,589,222 45,717,866 RGD:1600115
RGD:1624291
G Pycard PYD and CARD domain containing GBrowse link 1 187,276,089 187,277,122 RGD:1600115
RGD:1624291
G Rap1a RAP1A, member of RAS oncogene family GBrowse link 2 200,980,324 201,001,561 RGD:1624291
RGD:8554481
G Rap1b RAP1B, member of RAS oncogene family GBrowse link 7 57,132,750 57,139,811 RGD:1624291
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 GBrowse link 2 170,472,420 170,587,987 RGD:1600115
RGD:1624291
RGD:8554481
G Rara retinoic acid receptor, alpha GBrowse link 10 87,740,479 87,753,265 RGD:8553301
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link 5 30,714,817 30,745,941 RGD:1600115
RGD:1624291
G S100a7a S100 calcium binding protein A7A GBrowse link 2 182,946,273 182,950,714 RGD:1624291
G Scimp SLP adaptor and CSK interacting membrane protein GBrowse link 10 57,687,664 57,707,493 RGD:1600115
RGD:1624291
G Sema7a semaphorin 7A, GPI membrane anchor GBrowse link 8 61,717,449 61,739,529 RGD:1624291
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link 10 62,748,116 62,756,200 RGD:1600115
RGD:1624291
G Spry2 sprouty homolog 2 (Drosophila) GBrowse link 15 90,009,109 90,011,940 RGD:1600115
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase GBrowse link 3 148,157,256 148,170,524 RGD:1624291
RGD:8553998
G St5 suppression of tumorigenicity 5 GBrowse link 1 167,119,711 167,284,482 RGD:1600115
RGD:1624291
G Tek TEK tyrosine kinase, endothelial GBrowse link 5 115,047,195 115,196,172 RGD:1600115
RGD:1624291
G Tff2 trefoil factor 2 GBrowse link 20 9,492,341 9,510,558 RGD:1600115
RGD:1624291
G Thpo thrombopoietin GBrowse link 11 82,412,552 82,417,807 RGD:1600115
RGD:1624291
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link 8 34,966,856 34,969,727 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 GBrowse link 5 83,564,100 83,577,735 RGD:1600115
RGD:1624291
G Trem2 triggering receptor expressed on myeloid cells 2 GBrowse link 9 8,059,023 8,065,585 RGD:1624291
G Vegfa vascular endothelial growth factor A GBrowse link 9 10,520,730 10,536,071 RGD:1600115
RGD:1624291
G Vegfb vascular endothelial growth factor B GBrowse link 1 209,657,632 209,661,271 RGD:1600115
RGD:1624291
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator GBrowse link 13 11,958,002 12,014,371 RGD:1600115
RGD:1624291
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link 15 59,397,837 59,428,014 RGD:1624291
positive regulation of JNK cascade term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Ankrd6 ankyrin repeat domain 6 GBrowse link 5 49,098,952 49,211,771 RGD:1600115
G Axin1 axin 1 GBrowse link 10 15,409,373 15,462,726 RGD:1600115
RGD:1624291
G Card9 caspase recruitment domain family, member 9 GBrowse link 3 4,524,781 4,533,412 RGD:1624291
G Ccl19 chemokine (C-C motif) ligand 19 GBrowse link 5 59,221,738 59,223,682 RGD:1600115
RGD:1624291
G Ccl21 chemokine (C-C motif) ligand 21 GBrowse link 5 59,238,897 59,240,001 RGD:1600115
RGD:1624291
G Cd27 CD27 molecule GBrowse link 4 161,351,797 161,356,688 RGD:1600115
RGD:1624291
G Cdc42 cell division cycle 42 GBrowse link 5 156,106,123 156,143,040 RGD:2298583
G Ctgf connective tissue growth factor GBrowse link 1 21,327,099 21,330,215 RGD:1600115
RGD:1624291
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1600115
RGD:1624291
G Dixdc1 DIX domain containing 1 GBrowse link 8 54,018,179 54,073,235 RGD:2308917
G Dusp15 dual specificity phosphatase 15 GBrowse link 3 143,285,894 143,294,571 RGD:1600115
G Dusp19 dual specificity phosphatase 19 GBrowse link 3 63,473,333 63,485,843 RGD:1624291
G Dusp22 dual specificity phosphatase 22 GBrowse link 17 40,229,790 40,281,414 RGD:1600115
RGD:1624291
G Eda2r ectodysplasin A2 receptor GBrowse link X 85,010,195 85,049,670 RGD:1600115
RGD:1624291
G F2rl1 coagulation factor II (thrombin) receptor-like 1 GBrowse link 2 25,886,177 25,899,128 RGD:1600115
RGD:1624291
G Fgf19 fibroblast growth factor 19 GBrowse link 1 205,324,890 205,328,178 RGD:1600115
RGD:1624291
G Flt4 fms-related tyrosine kinase 4 GBrowse link 10 35,071,002 35,112,006 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link 4 96,649,941 96,652,243 RGD:1600115
RGD:1624291
G Gadd45b growth arrest and DNA-damage-inducible, beta GBrowse link 7 10,289,073 10,291,102 RGD:1600115
RGD:1624291
G Gadd45g growth arrest and DNA-damage-inducible, gamma GBrowse link 17 19,230,896 19,232,641 RGD:1600115
RGD:1624291
G Hipk2 homeodomain interacting protein kinase 2 GBrowse link 4 66,273,623 66,455,774 RGD:1600115
RGD:1624291
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1600115
RGD:1624291
G Il1a interleukin 1 alpha GBrowse link 3 116,913,612 116,924,114 RGD:1358666
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1358666
RGD:1600115
RGD:1624291
G Il3 interleukin 3 GBrowse link 10 39,684,691 39,687,041 RGD:1600115
RGD:1624291
G Ltbr lymphotoxin beta receptor (TNFR superfamily, member 3) GBrowse link 4 161,431,864 161,438,265 RGD:1600115
RGD:1624291
G Map3k10 mitogen activated protein kinase kinase kinase 10 GBrowse link 1 82,750,424 82,768,725 RGD:1600115
RGD:1624291
G Map3k11 mitogen-activated protein kinase kinase kinase 11 GBrowse link 1 208,312,955 208,326,289 RGD:1600115
RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 GBrowse link 5 48,252,637 48,308,820 RGD:1624291
G Map4k2 mitogen activated protein kinase kinase kinase kinase 2 GBrowse link 1 209,121,164 209,136,316 RGD:1600115
RGD:1624291
G Mink1 misshapen-like kinase 1 GBrowse link 10 57,443,253 57,496,763 RGD:1600115
RGD:1624291
G Myd88 myeloid differentiation primary response 88 GBrowse link 8 124,299,729 124,303,798 RGD:1600115
RGD:1624291
G Nod1 nucleotide-binding oligomerization domain containing 1 GBrowse link 4 83,398,809 83,449,207 RGD:1600115
RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link 19 19,662,337 19,697,341 RGD:1624291
G Nox1 NADPH oxidase 1 RGD:1624291
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link 3 122,797,718 123,523,675 RGD:1600115
RGD:1624291
G Ptk2b protein tyrosine kinase 2 beta GBrowse link 15 45,589,222 45,717,866 RGD:1600115
RGD:1624291
G Pycard PYD and CARD domain containing GBrowse link 1 187,276,089 187,277,122 RGD:1600115
RGD:1624291
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 GBrowse link 17 37,183,591 37,216,533 RGD:1600115
RGD:1624291
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link 5 30,714,817 30,745,941 RGD:1600115
RGD:1624291
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link 10 62,748,116 62,756,200 RGD:1600115
RGD:1624291
G Stk3 serine/threonine kinase 3 GBrowse link 7 70,308,195 70,597,445 RGD:1600115
RGD:1624291
G Taok1 TAO kinase 1 GBrowse link 10 66,503,966 66,584,625 RGD:1600115
RGD:1624291
G Taok2 TAO kinase 2 GBrowse link 1 186,049,010 186,063,423 RGD:1600115
RGD:1624291
G Taok3 TAO kinase 3 GBrowse link 12 40,502,499 40,583,816 RGD:1600115
RGD:1624291
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein GBrowse link 8 34,966,856 34,969,727 RGD:1600115
RGD:1624291
G Tlr3 toll-like receptor 3 GBrowse link 16 50,112,910 50,126,371 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 GBrowse link 5 83,564,100 83,577,735 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:1600115
RGD:1624291
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link 15 59,397,837 59,428,014 RGD:1624291
G Tpd52l1 tumor protein D52-like 1 GBrowse link 1 26,788,964 26,951,930 RGD:1600115
RGD:1624291
G Traf4 Tnf receptor associated factor 4 GBrowse link 10 64,471,018 64,477,122 RGD:1600115
RGD:1624291
G Unc5cl unc-5 homolog C (C. elegans)-like RGD:1624291
G Wnt16 wingless-type MMTV integration site family, member 16 GBrowse link 4 48,609,677 48,620,317 RGD:1600115
RGD:1624291
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link 16 3,782,025 3,799,625 RGD:1600115
RGD:1624291
G Wnt7a wingless-type MMTV integration site family, member 7A GBrowse link 4 125,541,281 125,586,167 RGD:4107045
G Wnt7b wingless-type MMTV integration site family, member 7B GBrowse link 7 123,533,713 123,554,333 RGD:2292645
G Zfp622 zinc finger protein 622 GBrowse link 2 77,571,866 77,585,706 RGD:1600115
RGD:1624291
positive regulation of JUN kinase activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Axin1 axin 1 GBrowse link 10 15,409,373 15,462,726 RGD:1624291
G Dab2ip DAB2 interacting protein GBrowse link 3 14,667,700 14,840,625 RGD:1624291
G Dusp19 dual specificity phosphatase 19 GBrowse link 3 63,473,333 63,485,843 RGD:1624291
G Dvl2 dishevelled segment polarity protein 2 RGD:1600115
RGD:1624291
G Dvl3 dishevelled segment polarity protein 3 GBrowse link 11 82,597,654 82,622,175 RGD:1600115
RGD:1624291
G Edn1 endothelin 1 GBrowse link 17 28,303,886 28,309,775 RGD:1600115
RGD:1624291
G Epha4 Eph receptor A4 GBrowse link 9 76,676,778 76,820,752 RGD:1600115
RGD:1624291
G Fzd10 frizzled class receptor 10 GBrowse link 12 29,164,632 29,166,832 RGD:1624291
G Fzd4 frizzled class receptor 4 GBrowse link 1 145,953,743 145,957,666 RGD:1600115
RGD:1624291
G Fzd5 frizzled class receptor 5 GBrowse link 9 63,386,990 63,388,747 RGD:1624291
G Fzd8 frizzled class receptor 8 GBrowse link 17 65,968,739 65,971,724 RGD:1624291
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1626684
G Il1rn interleukin 1 receptor antagonist GBrowse link 3 2,607,800 2,613,216 RGD:1626684
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link X 159,960,184 159,969,180 RGD:1624291
G LOC100361515 rCG34913-like GBrowse link 10 56,846,963 56,856,302 RGD:1600115
G Magi3 membrane associated guanylate kinase, WW and PDZ domain containing 3 GBrowse link 2 199,247,907 199,448,518 RGD:1600115
RGD:1624291
G Map3k1 mitogen activated protein kinase kinase kinase 1 GBrowse link 2 43,062,252 43,126,058 RGD:2293488
G Map3k10 mitogen activated protein kinase kinase kinase 10 GBrowse link 1 82,750,424 82,768,725 RGD:1600115
RGD:1624291
G Map3k11 mitogen-activated protein kinase kinase kinase 11 GBrowse link 1 208,312,955 208,326,289 RGD:1624291
G Map3k4 mitogen activated protein kinase kinase kinase 4 GBrowse link 1 42,891,172 42,978,862 RGD:1600115
RGD:1624291
G Map3k7 mitogen activated protein kinase kinase kinase 7 GBrowse link 5 48,252,637 48,308,820 RGD:1600115
RGD:1624291
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 GBrowse link 10 14,147,895 14,186,277 RGD:1624291
G Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 GBrowse link 1 155,057,622 155,174,714 RGD:1600115
RGD:1624291
RGD:8554570
G Ptk2b protein tyrosine kinase 2 beta GBrowse link 15 45,589,222 45,717,866 RGD:1642623
G Sash1 SAM and SH3 domain containing 1 GBrowse link 1 3,322,905 3,486,748 RGD:1624291
G Taok3 TAO kinase 3 GBrowse link 12 40,502,499 40,583,816 RGD:1600115
RGD:1624291
G Tlr6 toll-like receptor 6 GBrowse link 14 46,089,365 46,100,687 RGD:1600115
RGD:1624291
G Tlr9 toll-like receptor 9 RGD:1624291
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:1600115
RGD:1624291
G Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator GBrowse link 13 11,958,002 12,014,371 RGD:1600115
RGD:1624291
G Traf2 Tnf receptor-associated factor 2 GBrowse link 3 3,692,740 3,717,332 RGD:1600115
RGD:1624291
G Traf6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase GBrowse link 3 86,827,582 86,847,408 RGD:1600115
RGD:1624291
G Vangl2 VANGL planar cell polarity protein 2 GBrowse link 13 87,964,426 87,988,364 RGD:1600115
RGD:1624291
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link 16 3,782,025 3,799,625 RGD:1624291
G Zeb2 zinc finger E-box binding homeobox 2 GBrowse link 3 25,513,009 25,654,964 RGD:1600115
RGD:1624291
positive regulation of MAP kinase activity term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Adra2a adrenoceptor alpha 2A RGD:1624291
G Ajuba ajuba LIM protein GBrowse link 15 32,627,633 32,637,861 RGD:1600115
RGD:1624291
G Cd24 CD24 molecule GBrowse link 20 47,502,354 47,507,663 RGD:1600115
RGD:1624291
RGD:8554185
G Cd40 CD40 molecule, TNF receptor superfamily member 5 GBrowse link 3 156,092,602 156,107,427 RGD:1600115
RGD:1624291
RGD:2290270
G Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) GBrowse link 1 80,742,540 80,758,943 RGD:625644
G Csk c-src tyrosine kinase GBrowse link 8 61,381,336 61,386,013 RGD:5134370
G Diras1 DIRAS family, GTP-binding RAS-like 1 GBrowse link 7 10,171,727 10,176,591 RGD:1624291
G Diras2 DIRAS family, GTP-binding RAS-like 2 GBrowse link 17 18,604,023 18,605,223 RGD:1624291
G Edn1 endothelin 1 GBrowse link 17 28,303,886 28,309,775 RGD:1624291
G Edn3 endothelin 3 GBrowse link 3 166,491,368 166,514,051 RGD:1600115
RGD:1624291
G Egf epidermal growth factor GBrowse link 2 227,103,900 227,195,062 RGD:1624291
G Egfr epidermal growth factor receptor GBrowse link 14 97,617,358 97,788,211 RGD:1600115
RGD:1624291
G Epgn epithelial mitogen GBrowse link 14 18,573,036 18,579,934 RGD:1600115
RGD:1624291
G Erbb2 v-erb-b2 avian erythroblastic leukemia viral oncogene 2 GBrowse link 10 87,219,157 87,242,919 RGD:1600115
RGD:1624291
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit GBrowse link 4 75,709,959 75,773,279 RGD:1600115
RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 GBrowse link 16 70,869,974 70,910,045 RGD:1600115
RGD:1624291
G Flt1 FMS-related tyrosine kinase 1 GBrowse link 12 7,858,092 8,035,966 RGD:1600115
RGD:1624291
G Hras Harvey rat sarcoma virus oncogene GBrowse link 1 201,385,705 201,388,987 RGD:1600115
RGD:1624291
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled GBrowse link 15 55,463,743 55,532,293 RGD:1624373
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link 9 84,840,026 84,852,984 RGD:1600115
RGD:1624291
G Ilk integrin-linked kinase GBrowse link 1 163,481,299 163,487,550 RGD:2301767
G Irak1 interleukin-1 receptor-associated kinase 1 GBrowse link X 159,960,184 159,969,180 RGD:1624291
G Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link 14 34,906,043 34,984,819 RGD:1624291
G Kitlg KIT ligand GBrowse link 7 37,714,157 37,795,722 RGD:1600115
RGD:1624291
G Kras Kirsten rat sarcoma viral oncogene GBrowse link 4 182,869,242 182,895,106 RGD:1600497
G LOC100911280 vascular endothelial growth factor receptor 1-like RGD:1600115
G Maged1 melanoma antigen, family D, 1 GBrowse link X 82,054,042 82,060,563 RGD:1600115
RGD:1624291
G Map3k1 mitogen activated protein kinase kinase kinase 1 GBrowse link 2 43,062,252 43,126,058 RGD:2293488
G Mef2c myocyte enhancer factor 2C GBrowse link 2 12,331,078 12,346,520 RGD:8554846
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link 20 13,191,986 13,192,851 RGD:1624291
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) GBrowse link 8 113,175,977 113,189,511 RGD:1600115
RGD:1624291
G Nek10 NIMA-related kinase 10 GBrowse link 15 11,865,467 12,045,333 RGD:1624291
G Nox4 NADPH oxidase 4 GBrowse link 1 143,415,816 143,603,554 RGD:1600115
RGD:1624291
G Pdcd10 programmed cell death 10 GBrowse link 2 166,402,652 166,445,015 RGD:1600115
RGD:1624291
G Pde5a phosphodiesterase 5A, cGMP-specific GBrowse link 2 219,410,394 219,550,910 RGD:1600115
RGD:1624291
G Pdgfa platelet-derived growth factor alpha polypeptide GBrowse link 12 16,151,045 16,172,412 RGD:1600115
RGD:1624291
G Pdgfb platelet-derived growth factor beta polypeptide GBrowse link 7 118,244,385 118,262,021 RGD:1624291
RGD:8554838
G Pdgfrb platelet derived growth factor receptor, beta polypeptide GBrowse link 18 57,014,475 57,053,581 RGD:1600115
RGD:1624291
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma GBrowse link 6 50,441,892 50,476,931 RGD:1600115
RGD:1624291
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 GBrowse link 10 55,270,065 55,303,503 RGD:1600115
RGD:1624291
G Prkcd protein kinase C, delta GBrowse link 16 5,954,218 5,975,743 RGD:1642549
G Psen1 presenilin 1 GBrowse link 6 107,737,543 107,776,357 RGD:1600115
RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase GBrowse link 3 148,157,256 148,170,524 RGD:8553998
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 GBrowse link 7 118,368,997 118,402,928 RGD:5508182
G Tenm1 teneurin transmembrane protein 1 GBrowse link X 1,895,286 2,529,211 RGD:1624291
G Tgfb1 transforming growth factor, beta 1 GBrowse link 1 80,894,705 80,911,020 RGD:1600115
RGD:1624291
G Tnf tumor necrosis factor GBrowse link 20 3,661,000 3,663,618 RGD:1624291
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link 15 59,397,837 59,428,014 RGD:1624291
G Tpd52l1 tumor protein D52-like 1 GBrowse link 1 26,788,964 26,951,930 RGD:1600115
RGD:1624291
G Vegfa vascular endothelial growth factor A GBrowse link 9 10,520,730 10,536,071 RGD:1600115
RGD:1624291
positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Fgf21 fibroblast growth factor 21 GBrowse link 1 96,082,475 96,083,718 RGD:1600115
RGD:1624291
G Fgf23 fibroblast growth factor 23 GBrowse link 4 163,468,604 163,476,325 RGD:1600115
RGD:1624291
G Fgfr1 Fibroblast growth factor receptor 1 GBrowse link 16 70,869,974 70,910,045 RGD:1600115
RGD:1624291
G Fgfr3 fibroblast growth factor receptor 3 GBrowse link 14 82,683,191 82,697,229 RGD:1600115
RGD:1624291
G Kl Klotho GBrowse link 12 3,732,712 3,772,371 RGD:1600115
RGD:1624291
G Klb klotho beta GBrowse link 14 45,598,875 45,650,432 RGD:1600115
RGD:1624291
positive regulation of p38MAPK cascade term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 GBrowse link 3 121,372,692 121,381,236 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha GBrowse link 4 96,649,941 96,652,243 RGD:1600115
RGD:1624291
G Gadd45b growth arrest and DNA-damage-inducible, beta GBrowse link 7 10,289,073 10,291,102 RGD:1600115
RGD:1624291
G Gadd45g growth arrest and DNA-damage-inducible, gamma GBrowse link 17 19,230,896 19,232,641 RGD:1600115
RGD:1624291
G Map3k4 mitogen activated protein kinase kinase kinase 4 GBrowse link 1 42,891,172 42,978,862 RGD:1600115
RGD:1624291
G Sash1 SAM and SH3 domain containing 1 GBrowse link 1 3,322,905 3,486,748 RGD:1624291
G Vegfa vascular endothelial growth factor A GBrowse link 9 10,520,730 10,536,071 RGD:1600115
RGD:1624291
G Xdh xanthine dehydrogenase GBrowse link 6 21,417,685 21,590,015 RGD:1600115
RGD:1624291
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name GBrowse Chr Start Stop Reference
G Arl6ip5 ADP-ribosylation factor-like 6 interacting protein 5 GBrowse link 4 131,929,503 131,953,033 RGD:1624291
G Card9 caspase recruitment domain family, member 9 GBrowse link 3 4,524,781 4,533,412 RGD:1624291
G Crhr2 corticotropin releasing hormone receptor 2 GBrowse link 4 83,839,822 83,867,017 RGD:5130956
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 RGD:1600115
RGD:1624291
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase GBrowse link 2 27,127,504 27,149,580 RGD:5508698
G Il1a interleukin 1 alpha GBrowse link 3 116,913,612 116,924,114 RGD:1358666
G Il1b interleukin 1 beta GBrowse link 3 116,964,422 116,970,867 RGD:1358666
RGD:1626685
G Kiss1 KiSS-1 metastasis-suppressor GBrowse link 13 46,244,786 46,247,288 RGD:1599289
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 GBrowse link 7 127,773,156 127,780,772 RGD:2302280
G Mid1 midline 1 GBrowse link X 44,751,950 44,879,999 RGD:1600115
RGD:1624291
G Nod1 nucleotide-binding oligomerization domain containing 1 GBrowse link 4 83,398,809 83,449,207 RGD:1624291
G Nod2 nucleotide-binding oligomerization domain containing 2 GBrowse link 19 19,662,337 19,697,341 RGD:1600115
RGD:1624291
G Ripk2 receptor-interacting serine-threonine kinase 2 GBrowse link 5 30,714,817 30,745,941 RGD:1624291
G Sema4c sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C GBrowse link 9 35,492,647 35,503,102 RGD:1600115
RGD:1624291
G Taok1 TAO kinase 1 GBrowse link 10 66,503,966 66,584,625 RGD:1600115
RGD:1624291
G Taok2 TAO kinase 2 GBrowse link 1 186,049,010 186,063,423 RGD:1600115
RGD:1624291
G Taok3 TAO kinase 3 GBrowse link 12 40,502,499 40,583,816 RGD:1600115
RGD:1624291
G Tgfb2 transforming growth factor, beta 2 GBrowse link 13 102,718,703 102,818,768 RGD:1600115
RGD:1624291
G Tlr4 toll-like receptor 4 GBrowse link 5 83,564,100 83,577,735 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 171926
    positive regulation of biological process 23445
      positive regulation of signaling 3341
        positive regulation of signal transduction 3144
          positive regulation of intracellular signal transduction 2005
            positive regulation of MAPK cascade 916
              positive regulation of ERK1 and ERK2 cascade + 263
              positive regulation of ERK5 cascade 0
              positive regulation of MAP kinase activity + 342
              positive regulation of MAPK cascade involved in cell wall organization or biogenesis 0
              positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 12
              positive regulation of stress-activated MAPK cascade + 163
Path 2
Term Annotations click to browse term
  biological_process 171926
    biological regulation 72558
      regulation of biological process 66499
        regulation of metabolic process 22703
          regulation of cellular metabolic process 18713
            regulation of phosphorus metabolic process 5315
              regulation of phosphate metabolic process 5297
                regulation of phosphorylation 3600
                  positive regulation of phosphorylation 2272
                    positive regulation of MAPK cascade 916
                      positive regulation of ERK1 and ERK2 cascade + 263
                      positive regulation of ERK5 cascade 0
                      positive regulation of MAP kinase activity + 342
                      positive regulation of MAPK cascade involved in cell wall organization or biogenesis 0
                      positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway 12
                      positive regulation of stress-activated MAPK cascade + 163
paths to the root