negative regulation of MAP kinase activity - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	negative regulation of MAP kinase activity	go back to main search page
Accession:	GO:0043407	browse the term
Definition:	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
Synonyms:	exact_synonym:	down regulation of MAPK activity; downregulation of MAPK activity; negative regulation of mitogen activated protein kinase activity
	narrow_synonym:	inhibition of MAPK activity

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negative regulation of MAP kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Adipoq	adiponectin, C1Q and collagen domain containing		ISO	11	79,908,291	79,911,065	RGD:1624291	RGD
G	Adipoq	adiponectin, C1Q and collagen domain containing		ISS	11	79,908,291	79,911,065	RGD:1600115	UniProtKB
G	Apoe	apolipoprotein E		ISO	1	79,003,634	79,006,387	RGD:1624291	RGD
G	Apoe	apolipoprotein E		IEA	1	79,003,634	79,006,387	RGD:1600115	ENSEMBL
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
G	Bmp7	bone morphogenetic protein 7		ISO	3	163,723,429	163,799,567	RGD:1624291	RGD
G	Bmp7	bone morphogenetic protein 7		IEA	3	163,723,429	163,799,567	RGD:1600115	ENSEMBL
G	Cav1	caveolin 1, caveolae protein		ISO	4	42,956,102	42,989,057	RGD:1624291	RGD
G	Cav3	caveolin 3		ISO	4	148,294,428	148,310,380	RGD:1624291	RGD
G	Cav3	caveolin 3		IEA	4	148,294,428	148,310,380	RGD:1600115	ENSEMBL
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		IEA	1	79,091,412	79,108,189	RGD:1600115	ENSEMBL
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		ISO	1	79,091,412	79,108,189	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISS	3	14,667,700	14,840,625	RGD:1600115	UniProtKB
G	Dusp7	dual specificity phosphatase 7		ISO	8	111,510,358	111,515,989	RGD:1624291	RGD
G	Fem1a	fem-1 homolog a (C. elegans)		ISO				RGD:1624291	RGD
G	Gba	glucosidase, beta, acid		ISO				RGD:1624291	RGD
G	Gba	glucosidase, beta, acid		IEA				RGD:1600115	ENSEMBL
G	Gsk3b	glycogen synthase kinase 3 beta		IMP	11	64,284,731	64,428,698	RGD:2301767	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Hmgcr	3-hydroxy-3-methylglutaryl-CoA reductase		ISO	2	27,127,504	27,149,580	RGD:1624291	RGD
G	Hmgcr	3-hydroxy-3-methylglutaryl-CoA reductase		IEA	2	27,127,504	27,149,580	RGD:1600115	ENSEMBL
G	Hyal2	hyaluronoglucosaminidase 2		ISO	8	112,817,001	112,820,693	RGD:1624291	RGD
G	Hyal2	hyaluronoglucosaminidase 2		IEA	8	112,817,001	112,820,693	RGD:1600115	ENSEMBL
G	Hyal2	hyaluronoglucosaminidase 2		ISS	8	112,817,001	112,820,693	RGD:1600115	UniProtKB
G	Il1b	interleukin 1 beta		ISO	3	116,964,422	116,970,867	RGD:1624291	RGD
G	Il1b	interleukin 1 beta		IEA	3	116,964,422	116,970,867	RGD:1600115	ENSEMBL
G	Inpp5k	inositol polyphosphate-5-phosphatase K		ISO	10	62,953,425	62,971,016	RGD:1624291	RGD
G	Inppl1	inositol polyphosphate phosphatase-like 1		IMP	1	159,278,131	159,292,740	RGD:1626126	RGD
G	Irak3	interleukin-1 receptor-associated kinase 3		ISO	7	59,408,198	59,467,821	RGD:1624291	RGD
G	Irak3	interleukin-1 receptor-associated kinase 3		IEA	7	59,408,198	59,467,821	RGD:1600115	ENSEMBL
G	Irak3	interleukin-1 receptor-associated kinase 3		ISO	7	59,408,198	59,467,821	RGD:1624291	RGD
G	Kng1	kininogen 1		IDA	11	80,109,499	80,131,887	RGD:1600541	RGD
G	Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog		ISO	5	16,933,111	17,054,564	RGD:1624291	RGD
G	Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog		ISS	5	16,933,111	17,054,564	RGD:1600115	UniProtKB
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISS	10	65,574,833	65,766,305	RGD:1600115	HGNC
G	Nup62	nucleoporin 62		ISO	1	95,288,019	95,303,545	RGD:1624291	RGD
G	Nup62	nucleoporin 62		IEA	1	95,288,019	95,303,545	RGD:1600115	ENSEMBL
G	Prkcd	protein kinase C, delta		ISO	16	5,954,218	5,975,743	RGD:1624291	RGD
G	Prkcd	protein kinase C, delta		IEA	16	5,954,218	5,975,743	RGD:1600115	ENSEMBL
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		ISO	4	160,843,699	160,868,856	RGD:1624291	RGD
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		ISO	4	160,843,699	160,868,856	RGD:1624291	RGD
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		IEA	4	160,843,699	160,868,856	RGD:1600115	ENSEMBL
G	Ptprj	protein tyrosine phosphatase, receptor type, J		ISO	3	74,796,764	74,935,540	RGD:1624291	RGD
G	Ptprj	protein tyrosine phosphatase, receptor type, J		ISO	3	74,796,764	74,935,540	RGD:1624291	RGD
G	Rgs14	regulator of G-protein signaling 14		ISO	17	15,293,100	15,307,162	RGD:1624291	RGD
G	Rgs14	regulator of G-protein signaling 14		ISS	17	15,293,100	15,307,162	RGD:1600115	UniProtKB
G	Rgs2	regulator of G-protein signaling 2		ISO	13	57,891,849	57,894,452	RGD:1624291	RGD
G	Rgs2	regulator of G-protein signaling 2		IEA	13	57,891,849	57,894,452	RGD:1600115	ENSEMBL
G	Smpd1	sphingomyelin phosphodiesterase 1, acid lysosomal		ISO	1	163,278,970	163,282,813	RGD:1624291	RGD
G	Smpd1	sphingomyelin phosphodiesterase 1, acid lysosomal		IEA	1	163,278,970	163,282,813	RGD:1600115	ENSEMBL
G	Spry1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)		IEA	2	124,213,692	124,218,334	RGD:1600115	ENSEMBL
G	Spry2	sprouty homolog 2 (Drosophila)		ISO	15	90,009,109	90,011,940	RGD:1624291	RGD
G	Spry2	sprouty homolog 2 (Drosophila)		IEA	15	90,009,109	90,011,940	RGD:1600115	ENSEMBL
G	Spry4	sprouty homolog 4 (Drosophila)		ISO	18	31,532,680	31,547,586	RGD:1624291	RGD
G	Spry4	sprouty homolog 4 (Drosophila)		IEA	18	31,532,680	31,547,586	RGD:1600115	ENSEMBL
G	Tsc2	tuberous sclerosis 2		IMP	10	13,848,210	13,883,189	RGD:1580517	RGD
G	Uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)		ISO	14	44,114,392	44,124,947	RGD:1624291	RGD
G	Uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)		IEA	14	44,114,392	44,124,947	RGD:1600115	ENSEMBL
inactivation of MAPK activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Cav1	caveolin 1, caveolae protein		ISO	4	42,956,102	42,989,057	RGD:1624291	RGD
G	Cav1	caveolin 1, caveolae protein		IEA	4	42,956,102	42,989,057	RGD:1600115	ENSEMBL
G	Dusp1	dual specificity phosphatase 1		IBA	10	16,942,913	16,945,696	RGD:1600115	RefGenome
G	Dusp10	dual specificity phosphatase 10		IBA	13	100,022,421	100,059,539	RGD:1600115	RefGenome
G	Dusp10	dual specificity phosphatase 10		ISO	13	100,022,421	100,059,539	RGD:1624291	RGD
G	Dusp16	dual specificity phosphatase 16		ISO	4	171,620,395	171,667,593	RGD:1624291	RGD
G	Dusp16	dual specificity phosphatase 16		IBA	4	171,620,395	171,667,593	RGD:1600115	RefGenome
G	Dusp19	dual specificity phosphatase 19		ISO	3	63,473,333	63,485,843	RGD:1624291	RGD
G	Dusp19	dual specificity phosphatase 19		IEA	3	63,473,333	63,485,843	RGD:1600115	ENSEMBL
G	Dusp2	dual specificity phosphatase 2		IBA	3	114,838,605	114,840,790	RGD:1600115	RefGenome
G	Dusp3	dual specificity phosphatase 3		ISO	10	91,031,206	91,044,858	RGD:1624291	RGD
G	Dusp3	dual specificity phosphatase 3		IBA	10	91,031,206	91,044,858	RGD:1600115	GOC
G	Dusp4	dual specificity phosphatase 4		IBA	16	61,109,626	61,119,981	RGD:1600115	RefGenome
G	Dusp5	dual specificity phosphatase 5		IBA	1	259,754,234	259,767,645	RGD:1600115	RefGenome
G	Dusp6	dual specificity phosphatase 6		ISO	7	36,893,264	36,897,494	RGD:1624291	RGD
G	Dusp6	dual specificity phosphatase 6		IBA	7	36,893,264	36,897,494	RGD:1600115	RefGenome
G	Dusp7	dual specificity phosphatase 7		IBA	8	111,510,358	111,515,989	RGD:1600115	RefGenome
G	Dusp9	dual specificity phosphatase 9		ISO	X	159,538,012	159,541,937	RGD:1624291	RGD
G	Dusp9	dual specificity phosphatase 9		IBA	X	159,538,012	159,541,937	RGD:1600115	RefGenome
G	Lax1	lymphocyte transmembrane adaptor 1		ISO	13	46,606,072	46,616,628	RGD:1624291	RGD
G	Lax1	lymphocyte transmembrane adaptor 1		IEA	13	46,606,072	46,616,628	RGD:1600115	ENSEMBL
G	Prkca	protein kinase C, alpha		ISO	10	97,367,196	97,638,910	RGD:1624291	RGD
G	Spred1	sprouty-related, EVH1 domain containing 1		ISO	3	103,184,312	103,246,353	RGD:1624291	RGD
G	Spred1	sprouty-related, EVH1 domain containing 1		IEA	3	103,184,312	103,246,353	RGD:1600115	ENSEMBL
G	Spred2	sprouty-related, EVH1 domain containing 2		ISO	14	100,775,869	100,797,717	RGD:1624291	RGD
G	Spred2	sprouty-related, EVH1 domain containing 2		IEA	14	100,775,869	100,797,717	RGD:1600115	ENSEMBL
G	Spred3	sprouty-related, EVH1 domain containing 3		ISO	1	84,295,411	84,303,809	RGD:1624291	RGD
G	Spred3	sprouty-related, EVH1 domain containing 3		IEA	1	84,295,411	84,303,809	RGD:1600115	ENSEMBL
negative regulation of JUN kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Aida	axin interactor, dorsalization associated		ISO	13	99,339,703	99,357,665	RGD:1624291	RGD
G	Aida	axin interactor, dorsalization associated		IEA	13	99,339,703	99,357,665	RGD:1600115	ENSEMBL
G	Aida	axin interactor, dorsalization associated		IEA	13	99,339,703	99,357,665	RGD:1600115	ENSEMBL
G	Aida	axin interactor, dorsalization associated		ISO	13	99,339,703	99,357,665	RGD:1624291	RGD
G	Dusp10	dual specificity phosphatase 10		ISO	13	100,022,421	100,059,539	RGD:1624291	RGD
G	Dusp10	dual specificity phosphatase 10		IBA	13	100,022,421	100,059,539	RGD:1600115	RefGenome
G	Dusp19	dual specificity phosphatase 19		ISO	3	63,473,333	63,485,843	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISS	1	206,627,398	206,629,866	RGD:1600115	BHF-UCL
G	Hipk3	homeodomain interacting protein kinase 3		ISO	3	89,749,949	89,816,787	RGD:1624291	RGD
G	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1		IMP	3	76,781,504	76,790,661	RGD:1299562	RGD
G	Pdcd4	programmed cell death 4		ISS	1	260,183,648	260,202,032	RGD:1600115	UniProtKB
G	Sfrp1	secreted frizzled-related protein 1		ISO	16	73,030,458	73,067,304	RGD:1624291	RGD
G	Sfrp1	secreted frizzled-related protein 1		IEA	16	73,030,458	73,067,304	RGD:1600115	ENSEMBL
G	Sfrp2	secreted frizzled-related protein 2		ISO	2	175,479,320	175,486,865	RGD:1624291	RGD
G	Sfrp2	secreted frizzled-related protein 2		IEA	2	175,479,320	175,486,865	RGD:1600115	ENSEMBL
G	Sfrp5	secreted frizzled-related protein 5		ISO	1	248,652,323	248,656,785	RGD:1624291	RGD
G	Sfrp5	secreted frizzled-related protein 5		IEA	1	248,652,323	248,656,785	RGD:1600115	ENSEMBL
G	Tp73	tumor protein p73		ISO	5	170,848,979	171,078,739	RGD:1624291	RGD
G	Tp73	tumor protein p73		IBA	5	170,848,979	171,078,739	RGD:1600115	RefGenome

Term paths to the root

Path 1
Term	Annotations
biological_process	135967
negative regulation of biological process	13304
negative regulation of signaling	1772
negative regulation of signal transduction	1699
negative regulation of intracellular protein kinase cascade	365
negative regulation of MAPK cascade	232
negative regulation of MAP kinase activity	116
inactivation of MAPK activity +	28
negative regulation of JUN kinase activity	23
Path 2
Term	Annotations
biological_process	135967
biological regulation	56440
regulation of biological process	51470
negative regulation of biological process	13304
negative regulation of cellular process	11066
negative regulation of cellular metabolic process	3509
negative regulation of phosphorus metabolic process	571
negative regulation of phosphate metabolic process	571
negative regulation of phosphorylation	488
negative regulation of protein phosphorylation	458
negative regulation of protein kinase activity	289
negative regulation of protein serine/threonine kinase activity	164
negative regulation of MAP kinase activity	116
inactivation of MAPK activity +	28
negative regulation of JUN kinase activity	23