amyloid precursor protein catabolic process - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	amyloid precursor protein catabolic process	go back to main search page
Accession:	GO:0042987	browse the term
Definition:	The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
Synonyms:	exact_synonym:	APP catabolic process; APP catabolism; amyloid precursor protein breakdown; amyloid precursor protein catabolism; amyloid precursor protein degradation

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amyloid precursor protein catabolic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Abcg1	ATP-binding cassette, subfamily G (WHITE), member 1		ISO	20	9,390,485	9,459,574	RGD:1624291	RGD
G	Abcg1	ATP-binding cassette, subfamily G (WHITE), member 1		IEA	20	9,390,485	9,459,574	RGD:1600115	ENSEMBL
G	Aph1a	anterior pharynx defective 1 homolog A (C. elegans)		ISO	2	190,679,692	190,683,202	RGD:1624291	RGD
G	Aph1a	anterior pharynx defective 1 homolog A (C. elegans)		IEA	2	190,679,692	190,683,202	RGD:1600115	ENSEMBL
G	Cln3	ceroid-lipofuscinosis, neuronal 3		ISO	1	185,713,096	185,724,375	RGD:1624291	RGD
G	Cln3	ceroid-lipofuscinosis, neuronal 3		ISS	1	185,713,096	185,724,375	RGD:1600115	UniProtKB
G	Dhcr24	24-dehydrocholesterol reductase		ISO	5	127,637,438	127,662,621	RGD:1624291	RGD
G	Dhcr24	24-dehydrocholesterol reductase		IEA	5	127,637,438	127,662,621	RGD:1600115	ENSEMBL
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Psen1	presenilin 1		IBA	6	107,737,543	107,776,357	RGD:1600115	RefGenome
beta-amyloid formation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Fkbp1a	FK506 binding protein 1a		ISO	3	141,861,237	141,880,797	RGD:1624291	RGD
G	Gsap	gamma-secretase activating protein		ISO	4	9,306,309	9,401,421	RGD:1624291	RGD
G	Gsap	gamma-secretase activating protein		ISO	4	9,306,309	9,401,421	RGD:1624291	RGD
G	Gsap	gamma-secretase activating protein		IEA	4	9,306,309	9,401,421	RGD:1600115	ENSEMBL
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)		ISO	6	109,396,504	109,411,292	RGD:1624291	RGD
G	Tmed10	transmembrane emp24-like trafficking protein 10 (yeast)		ISS	6	109,396,504	109,411,292	RGD:1600115	UniProtKB
positive regulation of beta-amyloid formation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Lrrtm3	leucine rich repeat transmembrane neuronal 3		ISO	20	26,343,897	26,518,838	RGD:1624291	RGD
G	Lrrtm3	leucine rich repeat transmembrane neuronal 3		ISO	20	26,343,897	26,518,838	RGD:1624291	RGD

Term paths to the root

Path 1
Term	Annotations
biological_process	135981
metabolic process	36384
primary metabolic process	29833
protein metabolic process	10747
amyloid precursor protein metabolic process	36
amyloid precursor protein catabolic process	21
beta-amyloid formation +	9
Path 2
Term	Annotations
biological_process	135981
metabolic process	36384
organic substance metabolic process	32718
macromolecule metabolic process	25173
protein metabolic process	10747
amyloid precursor protein metabolic process	36
amyloid precursor protein catabolic process	21
beta-amyloid formation +	9