ONTOLOGY REPORT - ANNOTATIONS

Term:senescence-associated heterochromatin focus
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Accession:GO:0035985 term browser browse the term
Definition:A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
Synonyms:exact_synonym: SAHF;   senescence-associated heterochromatin foci

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senescence-associated heterochromatin focus term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cdkn2a cyclin-dependent kinase inhibitor 2A GBrowse link ISO 5 108,908,749 108,916,380 RGD:1624291 RGD
G Hmga1 high mobility group AT-hook 1 GBrowse link ISS 20 5,769,052 5,772,269 RGD:1600115 UniProtKB
G Hmga2 high mobility group AT-hook 2 GBrowse link ISO 7 59,638,555 59,753,791 RGD:1624291 RGD
G Hmga2 high mobility group AT-hook 2 GBrowse link ISS 7 59,638,555 59,753,791 RGD:1600115 UniProtKB
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 76953
    organelle part 15043
      intracellular organelle part 14529
        chromosomal part 1391
          chromatin 611
            heterochromatin 136
              senescence-associated heterochromatin focus 4
Path 2
Term Annotations click to browse term
  cellular_component 76953
    cell 60947
      cell part 60939
        intracellular 47382
          intracellular part 46617
            intracellular organelle 34940
              intracellular non-membrane-bounded organelle 8789
                chromosome 1627
                  chromosomal part 1391
                    chromatin 611
                      heterochromatin 136
                        senescence-associated heterochromatin focus 4
paths to the root

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