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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of stress-activated MAPK cascade
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Accession:GO:0032872 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
Synonyms:exact_synonym: regulation of p38 MAPK signaling;   regulation of p38 MAPK signalling;   regulation of stress-activated MAPK signaling pathway;   regulation of stress-activated MAPK signalling pathway;   regulation of stress-activated MAPKKK cascade;   regulation of stress-activated MAPKKK signaling pathway;   regulation of stress-activated MAPKKK signalling pathway


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regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ENSRNOG00000067941 involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 Ensembl chr11:42,352,734...42,354,134 JBrowse link
G Fas Fas cell surface death receptor involved_in ISO
IBA
IEA		 (PMID:11096076)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:11096076 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist NOT|involved_in ISO (MGI:5318033|PMID:12135612) RGD PMID:12135612 MGI:5318033 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009198|PMID:10945608)		 BHF-UCL
RGD		 PMID:10945608 GO_REF:0000024 MGI:5009198 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in TAS
IEA		 PMID:19565474
GO_REF:0000117		 UniProt PMID:19565474 GO_REF:0000117, RGD:8553538 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nbr1 NBR1, autophagy cargo receptor involved_in IEA
ISO		 GO_REF:0000107
(MGI:4818844|PMID:20616007)		 Ensembl
RGD		 PMID:20616007 GO_REF:0000107 MGI:4818844 NCBI chr10:86,477,775...86,506,418
Ensembl chr10:86,478,290...86,506,412 		JBrowse link
G Prdx1 peroxiredoxin 1 acts_upstream_of_or_within ISO (PMID:16880205) RGD PMID:16880205 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 1:198,802,968...198,823,032
Ensembl chr 1:198,802,971...198,823,418 		JBrowse link
negative regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within ISO MGI:3052343 (PMID:19696743) RGD PMID:19696743 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Foxm1 forkhead box M1 involved_in ISO
IEA		 (PMID:19696738)
GO_REF:0000107		 RGD
Ensembl		 PMID:19696738 GO_REF:0000107 NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684 		JBrowse link
G Foxo1 forkhead box O1 involved_in ISO (PMID:19696738) RGD PMID:19696738 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5009411|PMID:16023107)		 BHF-UCL
RGD		 PMID:16023107 GO_REF:0000024 MGI:5009411 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:65,582,832...65,605,078
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:19545562) RGD PMID:19545562 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:26095851)		 UniProt
RGD		 PMID:26095851 GO_REF:0000024 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:11096076)
GO_REF:0000107		 RGD
Ensembl		 PMID:11096076 GO_REF:0000107 NCBI chr 8:109,207,705...109,215,738
Ensembl chr 8:109,207,705...109,215,739 		JBrowse link
positive regulation of stress-activated MAPK cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18387645)		 Ensembl
RGD		 PMID:18387645 GO_REF:0000107 NCBI chr 4:129,810,650...129,838,628
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:17187069)
(MGI:6117948|PMID:29080677)
MGI:3698412 (PMID:17187069)		 UniProt
RGD		 PMID:17187069 PMID:29080677 GO_REF:0000024 MGI:6117948 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:19211730 RGD:5130956 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5487533|PMID:20038207)		 UniProt
RGD		 PMID:20038207 GO_REF:0000024 MGI:5487533 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 involved_in ISO (PMID:24003225) RGD PMID:24003225 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:15671867 RGD:1358666 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IMP
IDA		 RGD PMID:12629164 PMID:15671867 RGD:1626685, RGD:1358666 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor NOT IMP RGD PMID:16222076 RGD:1599289 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Klhdc10 kelch domain containing 10 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:59,021,300...59,079,118
Ensembl chr 4:59,021,310...59,074,941 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 IMP RGD PMID:12024021 RGD:2302280 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Mid1 midline 1 involved_in ISO (PMID:17438131) RGD PMID:17438131 NCBI chr  X:24,116,674...24,491,205
Ensembl chr  X:24,120,293...24,248,353 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:17187069)
(PMID:18261938)		 RGD PMID:17187069 PMID:18261938 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA		 (PMID:22652780)
GO_REF:0000107		 RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098), (PMID:18261938) RGD PMID:11894097 PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (MGI:5803730|PMID:27288407) RGD PMID:27288407 MGI:5803730 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sema4c semaphorin 4C involved_in ISO (PMID:17498836) RGD PMID:17498836 NCBI chr 9:38,791,668...38,802,171
Ensembl chr 9:38,791,670...38,802,128 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO (PMID:22652780) RGD PMID:22652780 NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
G Taok1 TAO kinase 1 involved_in ISO
ISS		 (PMID:17396146)
GO_REF:0000024		 RGD
UniProt		 PMID:17396146 GO_REF:0000024 NCBI chr10:62,373,072...62,465,295
Ensembl chr10:62,381,404...62,465,766 		JBrowse link
G Taok2 TAO kinase 2 involved_in ISO
ISS
IEA		 (PMID:17396146)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Taok3 TAO kinase 3 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17396146)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17396146 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,312,354...39,473,656
Ensembl chr12:39,314,027...39,461,244 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17192487)		 UniProt
RGD		 PMID:17192487 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    regulation of biological process 13220
      regulation of cellular process 12685
        regulation of cellular response to stress 517
          regulation of stress-activated protein kinase signaling cascade 50
            regulation of stress-activated MAPK cascade 48
              negative regulation of stress-activated MAPK cascade + 10
              positive regulation of stress-activated MAPK cascade + 26
              regulation of cell wall integrity MAPK cascade + 0
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        regulation of cellular process 12685
          signal transduction 7163
            intracellular signal transduction 2818
              intracellular signaling cassette 1960
                MAPK cascade 808
                  regulation of MAPK cascade 707
                    regulation of stress-activated MAPK cascade 48
                      negative regulation of stress-activated MAPK cascade + 10
                      positive regulation of stress-activated MAPK cascade + 26
                      regulation of cell wall integrity MAPK cascade + 0
paths to the root