ONTOLOGY REPORT - ANNOTATIONS


Term:DNA duplex unwinding
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Accession:GO:0032508 term browser browse the term
Definition:The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
Comment:Note that this term refers to a geometric change in DNA conformation, and should not be confused with 'DNA topological change ; GO:0006265'.
Synonyms:exact_synonym: DNA unwinding;   duplex DNA melting


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DNA duplex unwinding term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ascc3 activating signal cointegrator 1 complex subunit 3 GBrowse link ISS 20 54,581,641 54,869,456 RGD:1600115 UniProtKB
G Chd8 chromodomain helicase DNA binding protein 8 GBrowse link ISO 15 27,642,767 27,704,443 RGD:1624291 RGD
G Ddx1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 GBrowse link ISO 6 36,794,602 36,825,473 RGD:1624291 RGD
G Ddx1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 GBrowse link ISS 6 36,794,602 36,825,473 RGD:1600115 UniProtKB
G Dna2 DNA replication helicase 2 homolog (yeast) GBrowse link ISO 20 25,288,326 25,316,851 RGD:1624291 RGD
G Ino80 INO80 homolog (S. cerevisiae) GBrowse link ISO 3 105,898,279 105,979,698 RGD:1624291 RGD
G Mre11a MRE11 meiotic recombination 11 homolog A (S. cerevisiae) GBrowse link ISO 8 11,588,409 11,632,483 RGD:1624291 RGD
G Nbn nibrin GBrowse link ISO 5 30,541,610 30,576,168 RGD:1624291 RGD
G Pot1 protection of telomeres 1 GBrowse link ISO 4 52,233,404 52,289,574 RGD:1624291 RGD
G Rad50 RAD50 homolog (S. cerevisiae) GBrowse link ISO 10 39,112,733 39,164,694 RGD:1624291 RGD
G Recql RecQ protein-like (DNA helicase Q1-like) GBrowse link ISO 4 179,927,255 179,951,742 RGD:1624291 RGD
G Recql4 RecQ protein-like 4 GBrowse link ISO 7 114,752,863 114,760,027 RGD:1624291 RGD
G Ruvbl1 RuvB-like 1 (E. coli) GBrowse link ISO 4 122,556,857 122,591,769 RGD:1624291 RGD
G Ruvbl2 RuvB-like 2 (E. coli) GBrowse link ISO 1 95,894,029 95,906,885 RGD:1624291 RGD
G Supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) GBrowse link ISO 20 29,681,431 29,714,796 RGD:1624291 RGD
G Supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) GBrowse link ISS 20 29,681,431 29,714,796 RGD:1600115 UniProtKB
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
G Wrn Werner syndrome, RecQ helicase-like GBrowse link ISO 16 62,535,144 62,668,700 RGD:1624291 RGD
DNA unwinding involved in replication term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G LOC100911267 DNA repair protein RAD51 homolog 1-like IEA RGD:1600115 ENSEMBL
G Mcm2 minichromosome maintenance complex component 2 GBrowse link ISO 4 122,977,522 122,991,934 RGD:1624291 RGD
G Mcm2 minichromosome maintenance complex component 2 GBrowse link IEA 4 122,977,522 122,991,934 RGD:1600115 ENSEMBL
G Mcm4 minichromosome maintenance complex component 4 GBrowse link ISO 11 87,169,742 87,183,443 RGD:1624291 RGD
G Mcm4 minichromosome maintenance complex component 4 GBrowse link IEA 11 87,169,742 87,183,443 RGD:1600115 ENSEMBL
G Mcm6 minichromosome maintenance complex component 6 GBrowse link ISO 13 41,045,677 41,070,868 RGD:1624291 RGD
G Mcm6 minichromosome maintenance complex component 6 GBrowse link IEA 13 41,045,677 41,070,868 RGD:1600115 ENSEMBL
G Mcm7 minichromosome maintenance complex component 7 GBrowse link ISO 12 17,607,250 17,614,508 RGD:1624291 RGD
G Mcm7 minichromosome maintenance complex component 7 GBrowse link IEA 12 17,607,250 17,614,508 RGD:1600115 ENSEMBL
G Peo1 progressive external ophthalmoplegia 1 GBrowse link ISO 1 250,073,350 250,079,743 RGD:1624291 RGD
G Peo1 progressive external ophthalmoplegia 1 GBrowse link IEA 1 250,073,350 250,079,743 RGD:1600115 ENSEMBL
G Pura purine rich element binding protein A GBrowse link ISO 18 28,916,722 28,925,008 RGD:1624291 RGD
G Pura purine rich element binding protein A GBrowse link IEA 18 28,916,722 28,925,008 RGD:1600115 ENSEMBL
G Rad51 RAD51 homolog (S. cerevisiae) GBrowse link ISO 3 105,625,265 105,650,392 RGD:1624291 RGD
nucleotide-excision repair, DNA duplex unwinding term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 GBrowse link ISO 18 24,684,912 24,716,143 RGD:1624291 RGD
G Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 GBrowse link IEA 18 24,684,912 24,716,143 RGD:1600115 ENSEMBL

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    cellular process 85138
      cellular metabolic process 30423
        cellular macromolecule metabolic process 21835
          DNA metabolic process 2273
            DNA conformation change 256
              DNA geometric change 39
                DNA duplex unwinding 34
                  DNA unwinding involved in replication 14
                  nucleotide-excision repair, DNA duplex unwinding 2
Path 2
Term Annotations click to browse term
  biological_process 135967
    metabolic process 36390
      cellular metabolic process 30423
        cellular nitrogen compound metabolic process 15301
          nucleobase-containing compound metabolic process 14436
            nucleic acid metabolic process 12471
              DNA metabolic process 2273
                DNA conformation change 256
                  DNA geometric change 39
                    DNA duplex unwinding 34
                      DNA unwinding involved in replication 14
                      nucleotide-excision repair, DNA duplex unwinding 2
paths to the root