ONTOLOGY REPORT - ANNOTATIONS

Term:zymogen activation
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Accession:GO:0031638 term browser browse the term
Definition:The proteolytic processing of an inactive enzyme to an active form.
Synonyms:exact_synonym: zymogen activation by proteolytic cleavage

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zymogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ctsh cathepsin H GBrowse link ISO 8 94,971,689 94,990,434 RGD:1624291 RGD
G Ctsh cathepsin H GBrowse link ISO 8 94,971,689 94,990,434 RGD:1624291 RGD
G Ctsh cathepsin H GBrowse link ISS 8 94,971,689 94,990,434 RGD:1600115 UniProtKB
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
G LOC679835 similar to Anionic trypsin II precursor (Pretrypsinogen II) GBrowse link ISO 4 69,144,579 69,149,045 RGD:1624291 RGD
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) GBrowse link ISO 15 32,493,852 32,503,077 RGD:1624291 RGD
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) GBrowse link IEA 15 32,493,852 32,503,077 RGD:1600115 ENSEMBL
G Prss12 protease, serine, 12 neurotrypsin (motopsin) GBrowse link ISO 2 220,194,590 220,254,502 RGD:1624291 RGD
G Prss12 protease, serine, 12 neurotrypsin (motopsin) GBrowse link IEA 2 220,194,590 220,254,502 RGD:1600115 ENSEMBL
negative regulation of plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cpb2 carboxypeptidase B2 (plasma) GBrowse link IMP 15 56,104,920 56,154,321 RGD:7243115 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IEA 12 20,931,996 20,942,374 RGD:1600115 ENSEMBL
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link ISO 9 79,091,414 79,166,330 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link ISO 9 79,091,414 79,166,330 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link IEA 9 79,091,414 79,166,330 RGD:1600115 ENSEMBL
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link ISO 10 62,748,116 62,756,200 RGD:1624291 RGD
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link IEA 10 62,748,116 62,756,200 RGD:1600115 ENSEMBL
G Thbs1 thrombospondin 1 ISO RGD:1624291 RGD
plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Apoh apolipoprotein H (beta-2-glycoprotein I) GBrowse link ISO 10 97,725,088 97,739,213 RGD:1624291 RGD
G Apoh apolipoprotein H (beta-2-glycoprotein I) GBrowse link IEA 10 97,725,088 97,739,213 RGD:1600115 ENSEMBL
G Dhcr24 24-dehydrocholesterol reductase GBrowse link ISO 5 127,637,438 127,662,621 RGD:1624291 RGD
G Dhcr24 24-dehydrocholesterol reductase GBrowse link IEA 5 127,637,438 127,662,621 RGD:1600115 ENSEMBL
G F11 coagulation factor XI GBrowse link ISO 16 50,276,330 50,298,903 RGD:1624291 RGD
G F11 coagulation factor XI GBrowse link IEA 16 50,276,330 50,298,903 RGD:1600115 ENSEMBL
G Hist1h2ba histone cluster 1, H2ba GBrowse link ISO 17 48,290,185 48,290,654 RGD:1624291 RGD
G Hist1h2ba histone cluster 1, H2ba GBrowse link IEA 17 48,290,185 48,290,654 RGD:1600115 ENSEMBL
G Klkb1 kallikrein B, plasma 1 GBrowse link ISO 16 50,248,935 50,272,279 RGD:1624291 RGD
G Klkb1 kallikrein B, plasma 1 GBrowse link IEA 16 50,248,935 50,272,279 RGD:1600115 ENSEMBL
G Plat plasminogen activator, tissue GBrowse link ISO 16 73,711,323 73,736,328 RGD:1624291 RGD
G Plat plasminogen activator, tissue GBrowse link IEA 16 73,711,323 73,736,328 RGD:1600115 ENSEMBL
positive regulation of plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Clec3b C-type lectin domain family 3, member B ISO RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
G Hpn hepsin GBrowse link ISO 1 86,145,615 86,161,091 RGD:1624291 RGD
G Hpn hepsin GBrowse link ISS 1 86,145,615 86,161,091 RGD:1600115 UniProtKB
G LOC100912012 tetranectin-like ISS RGD:1600115 UniProtKB
G Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein GBrowse link ISO 1 233,030,393 233,042,659 RGD:1624291 RGD
G Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein GBrowse link IEA 1 233,030,393 233,042,659 RGD:1600115 ENSEMBL
trypsinogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cuzd1 CUB and zona pellucida-like domains 1 GBrowse link ISO 1 190,887,527 190,900,654 RGD:1624291 RGD
G Cuzd1 CUB and zona pellucida-like domains 1 GBrowse link ISS 1 190,887,527 190,900,654 RGD:1600115 UniProtKB
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    metabolic process 36390
      primary metabolic process 29834
        protein metabolic process 10746
          protein maturation 283
            protein processing 267
              zymogen activation 46
                plasminogen activation + 32
                trypsinogen activation 2
                zymogen activation in other organism + 0
Path 2
Term Annotations click to browse term
  biological_process 135967
    metabolic process 36390
      organic substance metabolic process 32723
        macromolecule metabolic process 25172
          gene expression 12130
            protein maturation 283
              protein processing 267
                zymogen activation 46
                  plasminogen activation + 32
                  trypsinogen activation 2
                  zymogen activation in other organism + 0
paths to the root

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