ONTOLOGY REPORT - ANNOTATIONS


Term:CD95 death-inducing signaling complex
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Accession:GO:0031265 term browser browse the term
Definition:A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
Synonyms:exact_synonym: CD95 DISC;   CD95 death-inducing signalling complex;   Fas death-inducing signaling complex


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CD95 death-inducing signaling complex term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Casp8 caspase 8 GBrowse link IDA 9 57,389,353 57,437,803 RGD:4143200 RGD
G Cflar CASP8 and FADD-like apoptosis regulator GBrowse link IDA 9 57,309,836 57,356,635 RGD:4143200 RGD
G Fadd Fas (TNFRSF6)-associated via death domain GBrowse link IDA 1 205,010,363 205,012,768 RGD:4143200 RGD
G Fadd Fas (TNFRSF6)-associated via death domain GBrowse link ISO 1 205,010,363 205,012,768 RGD:1624291 RGD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link IDA 1 238,259,443 238,274,745 RGD:4143200 RGD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link ISO 1 238,259,443 238,274,745 RGD:1624291 RGD
G Fas Fas (TNF receptor superfamily, member 6) GBrowse link ISO 1 238,259,443 238,274,745 RGD:1624291 RGD

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 76599
    macromolecular complex 9662
      protein complex 7827
        death-inducing signaling complex 16
          CD95 death-inducing signaling complex 7
Path 2
Term Annotations click to browse term
  cellular_component 76599
    cell 60574
      cell part 60566
        cell periphery 9071
          plasma membrane 8674
            plasma membrane part 3836
              death-inducing signaling complex 16
                CD95 death-inducing signaling complex 7
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