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Term: CD95 death-inducing signaling complex
Accession: GO:0031265
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Definition: A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
Synonyms: exact_synonym: CD95 DISC; CD95 death-inducing signalling complex; Fas death-inducing signaling complex
CD95 death-inducing signaling complex
G
Casp8
caspase 8
IDA
9
57,389,353
57,437,803
RGD:4143200
RGD
G
Cflar
CASP8 and FADD-like apoptosis regulator
IDA
9
57,309,836
57,356,635
RGD:4143200
RGD
G
Fadd
Fas (TNFRSF6)-associated via death domain
IDA
1
205,010,363
205,012,768
RGD:4143200
RGD
G
Fadd
Fas (TNFRSF6)-associated via death domain
ISO
1
205,010,363
205,012,768
RGD:1624291
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
IDA
1
238,259,443
238,274,745
RGD:4143200
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
ISO
1
238,259,443
238,274,745
RGD:1624291
RGD
G
Fas
Fas (TNF receptor superfamily, member 6)
ISO
1
238,259,443
238,274,745
RGD:1624291
RGD
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