ONTOLOGY REPORT - ANNOTATIONS

Term:pancreas development
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Accession:GO:0031016 term browser browse the term
Definition:The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
Synonyms:xref_analog: Wikipedia:Pancreas

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pancreas development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Acvr2b activin A receptor, type IIB GBrowse link ISO 8 124,364,330 124,395,748 RGD:1624291 RGD
G Acvr2b activin A receptor, type IIB GBrowse link IEA 8 124,364,330 124,395,748 RGD:1600115 ENSEMBL
G Afp alpha-fetoprotein GBrowse link IEP 14 19,092,563 19,110,728 RGD:2292043 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link ISO 8 75,692,099 75,771,159 RGD:1624291 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link ISO 8 75,692,099 75,771,159 RGD:1624291 RGD
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 GBrowse link IEA 8 75,692,099 75,771,159 RGD:1600115 ENSEMBL
G Apc adenomatous polyposis coli GBrowse link IEP 18 26,732,147 26,790,383 RGD:4110129 RGD
G Cckar cholecystokinin A receptor GBrowse link IEP 14 62,052,510 62,057,201 RGD:2313336 RGD
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link ISO 8 125,978,161 125,987,670 RGD:1624291 RGD
G Ctnnb1 catenin (cadherin associated protein), beta 1 GBrowse link IBA 8 125,978,161 125,987,670 RGD:1600115 RefGenome
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISO 4 104,016,940 104,078,261 RGD:1624291 RGD
G Fgf10 fibroblast growth factor 10 GBrowse link ISO 2 50,866,799 50,940,319 RGD:1624291 RGD
G Fgf10 fibroblast growth factor 10 GBrowse link IEA 2 50,866,799 50,940,319 RGD:1600115 ENSEMBL
G Gata6 GATA binding protein 6 GBrowse link ISO 18 2,504,264 2,534,648 RGD:1624291 RGD
G Gdf11 growth differentiation factor 11 GBrowse link ISO 7 2,182,467 2,191,454 RGD:1624291 RGD
G Gdf11 growth differentiation factor 11 GBrowse link IEA 7 2,182,467 2,191,454 RGD:1600115 ENSEMBL
G Hes1 hairy and enhancer of split 1 (Drosophila) GBrowse link ISO 11 72,603,482 72,605,673 RGD:1624291 RGD
G Hhex hematopoietically expressed homeobox GBrowse link ISO 1 241,736,542 241,742,129 RGD:1624291 RGD
G Hhex hematopoietically expressed homeobox GBrowse link IEA 1 241,736,542 241,742,129 RGD:1600115 ENSEMBL
G Ihh Indian hedgehog GBrowse link ISO 9 74,287,115 74,293,332 RGD:1624291 RGD
G Ihh Indian hedgehog GBrowse link ISO 9 74,287,115 74,293,332 RGD:1624291 RGD
G Ihh Indian hedgehog GBrowse link IEA 9 74,287,115 74,293,332 RGD:1600115 ENSEMBL
G Ildr2 immunoglobulin-like domain containing receptor 2 GBrowse link ISO 13 82,011,398 82,052,932 RGD:1624291 RGD
G Ildr2 immunoglobulin-like domain containing receptor 2 GBrowse link IEA 13 82,011,398 82,052,932 RGD:1600115 ENSEMBL
G Invs inversin GBrowse link ISO 5 64,962,873 65,120,158 RGD:1624291 RGD
G Isl1 ISL LIM homeobox 1 GBrowse link ISO 2 48,050,124 48,060,394 RGD:1624291 RGD
G Isl1 ISL LIM homeobox 1 GBrowse link IEA 2 48,050,124 48,060,394 RGD:1600115 ENSEMBL
G Meis2 Meis homeobox 2 GBrowse link IEP 3 101,915,966 102,117,215 RGD:2304272 RGD
G Met met proto-oncogene GBrowse link IEP 4 43,134,183 43,211,355 RGD:2317563 RGD
G Msln mesothelin GBrowse link IEP 10 15,017,162 15,022,823 RGD:2326046 RGD
G Onecut1 one cut homeobox 1 GBrowse link ISO 8 79,644,305 79,672,772 RGD:1624291 RGD
G Onecut2 one cut homeobox 2 GBrowse link ISO 18 60,547,891 60,594,526 RGD:1624291 RGD
G Pax2 paired box 2 GBrowse link IEA 1 249,804,055 249,895,306 RGD:1600115 ENSEMBL
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link IEP 2 1,923,309 1,970,238 RGD:2308896 RGD
G Pdx1 pancreatic and duodenal homeobox 1 IEP RGD:2311165 RGD
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD:1624291 RGD
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD:1624291 RGD
G Pnliprp1 pancreatic lipase-related protein 1 GBrowse link IEP 1 265,237,786 265,253,415 RGD:728275 RGD
G Prox1 prospero homeobox 1 GBrowse link IEA 13 106,421,541 106,471,350 RGD:1600115 ENSEMBL
G Prox1 prospero homeobox 1 GBrowse link ISO 13 106,421,541 106,471,350 RGD:1624291 RGD
G Ptf1a pancreas specific transcription factor, 1a GBrowse link ISO 17 93,494,689 93,496,543 RGD:1624291 RGD
G Ptprv protein tyrosine phosphatase, receptor type, V GBrowse link ISO 13 48,070,488 48,090,682 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link ISO 4 2,200,504 2,209,657 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link ISO 4 2,200,504 2,209,657 RGD:1624291 RGD
G Shh sonic hedgehog GBrowse link IEA 4 2,200,504 2,209,657 RGD:1600115 ENSEMBL
G Smad2 SMAD family member 2 GBrowse link ISO 18 73,180,520 73,241,707 RGD:1624291 RGD
G Smad2 SMAD family member 2 GBrowse link IEA 18 73,180,520 73,241,707 RGD:1600115 ENSEMBL
G Tgfb2 transforming growth factor, beta 2 GBrowse link IEP 13 102,718,703 102,818,768 RGD:2302093 RGD
determination of pancreatic left/right asymmetry term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccdc39 coiled-coil domain containing 39 GBrowse link ISO 2 120,117,112 120,154,958 RGD:1624291 RGD
G Ccdc40 coiled-coil domain containing 40 ISO RGD:1624291 RGD
G Dnaaf1 dynein, axonemal, assembly factor 1 GBrowse link ISO 19 49,821,884 49,842,234 RGD:1624291 RGD
G Nphp3 nephronophthisis 3 (adolescent) GBrowse link ISO 8 109,065,400 109,105,882 RGD:1624291 RGD
G Zic3 Zic family member 3 GBrowse link ISO X 143,128,118 143,139,155 RGD:1624291 RGD
endocrine pancreas development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Anxa1 annexin A1 GBrowse link IEP 1 223,478,436 223,494,455 RGD:2306957 RGD
G Bak1 BCL2-antagonist/killer 1 GBrowse link IEP 20 5,255,954 5,264,593 RGD:2315710 RGD
G Clu clusterin GBrowse link IMP 15 45,365,779 45,405,314 RGD:1582421 RGD
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISO 4 104,016,940 104,078,261 RGD:1624291 RGD
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISS 4 104,016,940 104,078,261 RGD:1600115 UniProtKB
G Foxa2 forkhead box A2 GBrowse link ISO 3 136,739,009 136,743,204 RGD:1624291 RGD
G Foxa2 forkhead box A2 GBrowse link IEA 3 136,739,009 136,743,204 RGD:1600115 ENSEMBL
G Foxa2 forkhead box A2 GBrowse link ISO 3 136,739,009 136,743,204 RGD:1624291 RGD
G Foxa2 forkhead box A2 GBrowse link IBA 3 136,739,009 136,743,204 RGD:1600115 RefGenome
G Gip gastric inhibitory polypeptide GBrowse link ISO 10 84,732,705 84,740,801 RGD:1624291 RGD
G Gip gastric inhibitory polypeptide GBrowse link IEA 10 84,732,705 84,740,801 RGD:1600115 ENSEMBL
G Gipr gastric inhibitory polypeptide receptor GBrowse link ISO 1 78,515,051 78,526,160 RGD:1624291 RGD
G Gipr gastric inhibitory polypeptide receptor GBrowse link IEA 1 78,515,051 78,526,160 RGD:1600115 ENSEMBL
G Hnf1a HNF1 homeobox A GBrowse link ISO 12 42,919,574 42,945,670 RGD:1624291 RGD
G Hnf1a HNF1 homeobox A GBrowse link IEA 12 42,919,574 42,945,670 RGD:1600115 ENSEMBL
G Hnf1b HNF1 homeobox B GBrowse link ISO 10 72,081,091 72,187,014 RGD:1624291 RGD
G Hnf1b HNF1 homeobox B GBrowse link ISS 10 72,081,091 72,187,014 UniProtKB
G Il6 interleukin 6 GBrowse link ISO 4 456,799 461,376 RGD:1624291 RGD
G Il6 interleukin 6 GBrowse link IEA 4 456,799 461,376 RGD:1600115 ENSEMBL
G Il6r interleukin 6 receptor GBrowse link ISO 2 182,078,049 182,128,135 RGD:1624291 RGD
G Insm1 insulinoma-associated 1 GBrowse link ISO 3 134,845,568 134,847,243 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link ISO 3 62,224,633 62,227,936 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link ISO 3 62,224,633 62,227,936 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link ISS 3 62,224,633 62,227,936 RGD:1600115 UniProtKB
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx6-1 NK6 homeobox 1 GBrowse link ISO 14 9,214,743 9,221,676 RGD:1624291 RGD
G Nkx6-2 NK6 homeobox 2 GBrowse link ISO 1 199,397,361 199,398,901 RGD:1624291 RGD
G Nkx6-2 NK6 homeobox 2 GBrowse link IEA 1 199,397,361 199,398,901 RGD:1600115 ENSEMBL
G Onecut1 one cut homeobox 1 GBrowse link ISO 8 79,644,305 79,672,772 RGD:1624291 RGD
G Onecut1 one cut homeobox 1 GBrowse link IEA 8 79,644,305 79,672,772 RGD:1600115 ENSEMBL
G Onecut2 one cut homeobox 2 GBrowse link ISO 18 60,547,891 60,594,526 RGD:1624291 RGD
G Pde3b phosphodiesterase 3B, cGMP-inhibited GBrowse link ISO 1 172,409,282 172,577,108 RGD:1624291 RGD
G Pde3b phosphodiesterase 3B, cGMP-inhibited GBrowse link IEA 1 172,409,282 172,577,108 RGD:1600115 ENSEMBL
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD:1624291 RGD
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
G Sox4 SRY (sex determining region Y)-box 4 GBrowse link ISO 17 42,172,863 42,177,590 RGD:1624291 RGD
G Sox9 SRY (sex determining region Y)-box 9 GBrowse link IMP 10 102,392,187 102,394,256 RGD:2290270 MGI
G Sox9 SRY (sex determining region Y)-box 9 GBrowse link IEA 10 102,392,187 102,394,256 RGD:1600115 ENSEMBL
G Sox9 SRY (sex determining region Y)-box 9 GBrowse link ISO 10 102,392,187 102,394,256 RGD:1624291 RGD
exocrine pancreas development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cela1 chymotrypsin-like elastase family, member 1 GBrowse link ISO 7 139,439,589 139,452,717 RGD:1624291 RGD
G Cela1 chymotrypsin-like elastase family, member 1 GBrowse link IEA 7 139,439,589 139,452,717 RGD:1600115 ENSEMBL
G Igf1 insulin-like growth factor 1 GBrowse link ISO 7 24,531,669 24,605,742 RGD:1624291 RGD
G Igf1 insulin-like growth factor 1 GBrowse link IEA 7 24,531,669 24,605,742 RGD:1600115 ENSEMBL
G Igf1r insulin-like growth factor 1 receptor GBrowse link ISO 1 122,704,976 122,990,007 RGD:1624291 RGD
G Igf1r insulin-like growth factor 1 receptor GBrowse link IEA 1 122,704,976 122,990,007 RGD:1600115 ENSEMBL
G Igf2 insulin-like growth factor 2 GBrowse link ISO 1 202,906,624 202,915,231 RGD:1624291 RGD
G Igf2 insulin-like growth factor 2 GBrowse link IEA 1 202,906,624 202,915,231 RGD:1600115 ENSEMBL
G Insr insulin receptor GBrowse link ISO 12 2,934,967 3,087,691 RGD:1624291 RGD
G Insr insulin receptor GBrowse link IEA 12 2,934,967 3,087,691 RGD:1600115 ENSEMBL
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD:1624291 RGD
G Pdx1 pancreatic and duodenal homeobox 1 IEA RGD:1600115 ENSEMBL
G Ptf1a pancreas specific transcription factor, 1a GBrowse link IDA 17 93,494,689 93,496,543 UniProtKB
G Smo smoothened, frizzled family receptor GBrowse link IBA 4 56,623,494 56,645,571 RGD:1600115 RefGenome
G Xbp1 X-box binding protein 1 GBrowse link ISO 14 86,151,910 86,156,975 RGD:1624291 RGD
G Xbp1 X-box binding protein 1 GBrowse link IEA 14 86,151,910 86,156,975 RGD:1600115 ENSEMBL
negative regulation of pancreatic A cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hes1 hairy and enhancer of split 1 (Drosophila) GBrowse link ISO 11 72,603,482 72,605,673 RGD:1624291 RGD
pancreas morphogenesis term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cela1 chymotrypsin-like elastase family, member 1 GBrowse link ISO 7 139,439,589 139,452,717 RGD:1624291 RGD
G Cela1 chymotrypsin-like elastase family, member 1 GBrowse link IEA 7 139,439,589 139,452,717 RGD:1600115 ENSEMBL
G Smo smoothened, frizzled family receptor GBrowse link ISO 4 56,623,494 56,645,571 RGD:1624291 RGD
G Smo smoothened, frizzled family receptor GBrowse link IEA 4 56,623,494 56,645,571 RGD:1600115 ENSEMBL
pancreatic A cell development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Pax6 paired box 6 GBrowse link ISO 3 91,127,605 91,149,178 RGD:1624291 RGD
G Pax6 paired box 6 GBrowse link ISO 3 91,127,605 91,149,178 RGD:1624291 RGD
G Pax6 paired box 6 GBrowse link IMP 3 91,127,605 91,149,178 BHF-UCL
pancreatic A cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gata6 GATA binding protein 6 GBrowse link ISO 18 2,504,264 2,534,648 RGD:1624291 RGD
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
pancreatic A cell fate commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Neurod1 neuronal differentiation 1 GBrowse link ISO 3 62,224,633 62,227,936 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link IEA 3 62,224,633 62,227,936 RGD:1600115 ENSEMBL
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link IEA 3 135,837,591 135,839,963 RGD:1600115 ENSEMBL
pancreatic D cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
pancreatic epsilon cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
pancreatic PP cell fate commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Neurod1 neuronal differentiation 1 GBrowse link ISO 3 62,224,633 62,227,936 RGD:1624291 RGD
G Neurod1 neuronal differentiation 1 GBrowse link IEA 3 62,224,633 62,227,936 RGD:1600115 ENSEMBL
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link IEA 3 135,837,591 135,839,963 RGD:1600115 ENSEMBL
positive regulation of type B pancreatic cell development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bad BCL2-associated agonist of cell death GBrowse link ISO 1 209,617,373 209,626,292 RGD:1624291 RGD
G Bad BCL2-associated agonist of cell death GBrowse link ISS 1 209,617,373 209,626,292 RGD:1600115 UniProtKB
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) GBrowse link IEA 1 231,342,761 231,499,447 RGD:1600115 ENSEMBL
type B pancreatic cell development term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Bmp4 bone morphogenetic protein 4 GBrowse link ISO 15 22,283,171 22,286,757 RGD:1624291 RGD
G Bmp4 bone morphogenetic protein 4 GBrowse link ISS 15 22,283,171 22,286,757 RGD:1600115 UniProtKB
G Bmp4 bone morphogenetic protein 4 GBrowse link IEA 15 22,283,171 22,286,757 RGD:1600115 ENSEMBL
G Bmp5 bone morphogenetic protein 5 GBrowse link ISO 8 80,593,053 80,717,015 RGD:1624291 RGD
G Bmp5 bone morphogenetic protein 5 GBrowse link IEA 8 80,593,053 80,717,015 RGD:1600115 ENSEMBL
G Bmp6 bone morphogenetic protein 6 GBrowse link ISO 17 32,380,199 32,689,295 RGD:1624291 RGD
G Bmp6 bone morphogenetic protein 6 GBrowse link IEA 17 32,380,199 32,689,295 RGD:1600115 ENSEMBL
G Cdk6 cyclin-dependent kinase 6 GBrowse link ISO 4 27,362,656 27,618,006 RGD:1624291 RGD
G Cdk6 cyclin-dependent kinase 6 GBrowse link IEA 4 27,362,656 27,618,006 RGD:1600115 ENSEMBL
G Insm1 insulinoma-associated 1 GBrowse link ISO 3 134,845,568 134,847,243 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link IEA 3 135,837,591 135,839,963 RGD:1600115 ENSEMBL
G Nkx6-1 NK6 homeobox 1 GBrowse link IEP 14 9,214,743 9,221,676 RGD:2326025 RGD
G Pdpk1 3-phosphoinositide dependent protein kinase-1 GBrowse link ISO 10 13,329,708 13,394,080 RGD:1624291 RGD
G Pdpk1 3-phosphoinositide dependent protein kinase-1 GBrowse link IEA 10 13,329,708 13,394,080 RGD:1600115 ENSEMBL
G Smo smoothened, frizzled family receptor GBrowse link ISO 4 56,623,494 56,645,571 RGD:1624291 RGD
G Smo smoothened, frizzled family receptor GBrowse link IEA 4 56,623,494 56,645,571 RGD:1600115 ENSEMBL
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link ISO 16 3,782,025 3,799,625 RGD:1624291 RGD
G Wnt5a wingless-type MMTV integration site family, member 5A GBrowse link IEA 16 3,782,025 3,799,625 RGD:1600115 ENSEMBL
type B pancreatic cell differentiation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gata6 GATA binding protein 6 GBrowse link ISO 18 2,504,264 2,534,648 RGD:1624291 RGD
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD:1624291 RGD
G Pdx1 pancreatic and duodenal homeobox 1 IMP BHF-UCL
G Rfx6 regulatory factor X, 6 GBrowse link ISO 20 30,344,712 30,391,212 RGD:1624291 RGD
type B pancreatic cell fate commitment term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link ISO 3 135,837,591 135,839,963 RGD:1624291 RGD
G Nkx2-2 NK2 homeobox 2 GBrowse link IEA 3 135,837,591 135,839,963 RGD:1600115 ENSEMBL
type B pancreatic cell maturation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) GBrowse link IEA 1 231,342,761 231,499,447 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    single-organism process 88399
      single-organism developmental process 22738
        pancreas development 160
          determination of pancreatic left/right asymmetry 5
          endocrine pancreas development + 87
          exocrine pancreas development 16
          pancreas morphogenesis + 4
Path 2
Term Annotations click to browse term
  biological_process 135967
    multicellular organismal process 37265
      single-multicellular organism process 36068
        multicellular organismal development 24588
          system development 21128
            organ development 14127
              pancreas development 160
                determination of pancreatic left/right asymmetry 5
                endocrine pancreas development + 87
                exocrine pancreas development 16
                pancreas morphogenesis + 4
paths to the root

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