BMP signaling pathway - Ontology Report

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ONTOLOGY REPORT - ANNOTATIONS

Term:	BMP signaling pathway	go back to main search page
Accession:	GO:0030509	browse the term
Definition:	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:	exact_synonym:	BMP signalling pathway; bone morphogenetic protein signaling pathway; bone morphogenetic protein signalling pathway
	related_synonym:	BMP receptor signaling pathway
	xref_analog:	Reactome:REACT_105000; Reactome:REACT_107332; Reactome:REACT_12034; Reactome:REACT_28579; Reactome:REACT_31763; Reactome:REACT_77157; Reactome:REACT_79322; Reactome:REACT_80158; Reactome:REACT_81213; Reactome:REACT_86022; Reactome:REACT_96139

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BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acvr1	activin A receptor, type I		ISO	3	40,191,727	40,260,488	RGD:1624291	RGD
G	Acvr1	activin A receptor, type I		IEA	3	40,191,727	40,260,488	RGD:1600115	ENSEMBL
G	Acvr2a	activin A receptor, type IIA		ISO	3	29,779,827	29,808,881	RGD:1624291	RGD
G	Acvr2a	activin A receptor, type IIA		ISO	3	29,779,827	29,808,881	RGD:1624291	RGD
G	Acvr2a	activin A receptor, type IIA		ISO	3	29,779,827	29,808,881	RGD:1624291	RGD
G	Acvr2a	activin A receptor, type IIA		ISO	3	29,779,827	29,808,881	RGD:1624291	RGD
G	Acvr2b	activin A receptor, type IIB		ISO	8	124,364,330	124,395,748	RGD:1624291	RGD
G	Acvr2b	activin A receptor, type IIB		ISO	8	124,364,330	124,395,748	RGD:1624291	RGD
G	Acvr2b	activin A receptor, type IIB		IEA	8	124,364,330	124,395,748	RGD:1600115	ENSEMBL
G	Acvrl1	activin A receptor type II-like 1		ISO	7	139,873,596	139,884,675	RGD:1624291	RGD
G	Acvrl1	activin A receptor type II-like 1		IEA	7	139,873,596	139,884,675	RGD:1600115	ENSEMBL
G	Acvrl1	activin A receptor type II-like 1		ISO	7	139,873,596	139,884,675	RGD:1624291	RGD
G	Bmp10	bone morphogenetic protein 10		ISO	4	121,596,150	121,601,778	RGD:1624291	RGD
G	Bmp10	bone morphogenetic protein 10		ISO	4	121,596,150	121,601,778	RGD:1624291	RGD
G	Bmp10	bone morphogenetic protein 10		IEA	4	121,596,150	121,601,778	RGD:1600115	ENSEMBL
G	Bmp2	bone morphogenetic protein 2		IDA	3	121,372,692	121,381,236	RGD:631753	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISS	3	121,372,692	121,381,236	RGD:1600115	UniProtKB
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp6	bone morphogenetic protein 6		ISO	17	32,380,199	32,689,295	RGD:1624291	RGD
G	Bmp6	bone morphogenetic protein 6		ISO	17	32,380,199	32,689,295	RGD:1624291	RGD
G	Bmp6	bone morphogenetic protein 6		ISO	17	32,380,199	32,689,295	RGD:1624291	RGD
G	Bmp6	bone morphogenetic protein 6		IEA	17	32,380,199	32,689,295	RGD:1600115	ENSEMBL
G	Bmp6	bone morphogenetic protein 6		IEA	17	32,380,199	32,689,295	RGD:1600115	ENSEMBL
G	Bmp7	bone morphogenetic protein 7		TAS	3	163,723,429	163,799,567	RGD:737843	RGD
G	Bmp7	bone morphogenetic protein 7		ISO	3	163,723,429	163,799,567	RGD:1624291	RGD
G	Bmp7	bone morphogenetic protein 7		ISO	3	163,723,429	163,799,567	RGD:1624291	RGD
G	Bmp7	bone morphogenetic protein 7		ISO	3	163,723,429	163,799,567	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		ISO	16	10,061,943	10,105,854	RGD:1624291	RGD
G	Bmpr1a	bone morphogenetic protein receptor, type IA		IEA	16	10,061,943	10,105,854	RGD:1600115	ENSEMBL
G	Bmpr1a	bone morphogenetic protein receptor, type IA		IEA	16	10,061,943	10,105,854	RGD:1600115	ENSEMBL
G	Bmpr1b	bone morphogenetic protein receptor, type IB		ISO	2	239,727,569	239,767,802	RGD:1624291	RGD
G	Bmpr1b	bone morphogenetic protein receptor, type IB		ISO	2	239,727,569	239,767,802	RGD:1624291	RGD
G	Bmpr1b	bone morphogenetic protein receptor, type IB		ISO	2	239,727,569	239,767,802	RGD:1624291	RGD
G	Bmpr1b	bone morphogenetic protein receptor, type IB		ISO	2	239,727,569	239,767,802	RGD:1624291	RGD
G	Bmpr1b	bone morphogenetic protein receptor, type IB		IEA	2	239,727,569	239,767,802	RGD:1600115	ENSEMBL
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Cfc1	cripto, FRL-1, cryptic family 1		ISO	9	33,280,037	33,287,118	RGD:1624291	RGD
G	Dsg4	desmoglein 4		ISO	18	12,173,507	12,209,833	RGD:1624291	RGD
G	Dsg4	desmoglein 4		IEA	18	12,173,507	12,209,833	RGD:1600115	ENSEMBL
G	Ecsit	ECSIT signalling integrator		ISO	8	21,180,813	21,188,450	RGD:1624291	RGD
G	Ecsit	ECSIT signalling integrator		IEA	8	21,180,813	21,188,450	RGD:1600115	ENSEMBL
G	Egr1	early growth response 1		ISO	18	27,343,919	27,346,117	RGD:1624291	RGD
G	Egr1	early growth response 1		IEA	18	27,343,919	27,346,117	RGD:1600115	ENSEMBL
G	Fgf8	fibroblast growth factor 8		ISO	1	250,951,023	250,956,730	RGD:1624291	RGD
G	Fgf8	fibroblast growth factor 8		IEA	1	250,951,023	250,956,730	RGD:1600115	ENSEMBL
G	Fst	follistatin		ISO	2	46,542,246	46,550,678	RGD:1624291	RGD
G	Fst	follistatin		IEA	2	46,542,246	46,550,678	RGD:1600115	ENSEMBL
G	Gata4	GATA binding protein 4		ISO	15	42,472,793	42,519,569	RGD:1624291	RGD
G	Gata4	GATA binding protein 4		IEA	15	42,472,793	42,519,569	RGD:1600115	ENSEMBL
G	Gdf2	growth differentiation factor 2		ISO				RGD:1624291	RGD
G	Gdf6	growth differentiation factor 6		ISO	5	23,739,175	23,756,140	RGD:1624291	RGD
G	Gdf6	growth differentiation factor 6		ISO	5	23,739,175	23,756,140	RGD:1624291	RGD
G	Gdf6	growth differentiation factor 6		IEA	5	23,739,175	23,756,140	RGD:1600115	ENSEMBL
G	Gdf6	growth differentiation factor 6		IEA	5	23,739,175	23,756,140	RGD:1600115	ENSEMBL
G	Gdf7	growth differentiation factor 7		ISO	6	31,857,104	31,861,428	RGD:1624291	RGD
G	Gdf7	growth differentiation factor 7		IEA	6	31,857,104	31,861,428	RGD:1600115	ENSEMBL
G	Gdf7	growth differentiation factor 7		IEA	6	31,857,104	31,861,428	RGD:1600115	ENSEMBL
G	Gdf7	growth differentiation factor 7		ISO	6	31,857,104	31,861,428	RGD:1624291	RGD
G	Hfe2	hemochromatosis type 2 (juvenile)		ISO	2	191,329,644	191,333,525	RGD:1624291	RGD
G	Hfe2	hemochromatosis type 2 (juvenile)		IEA	2	191,329,644	191,333,525	RGD:1600115	ENSEMBL
G	Id1	inhibitor of DNA binding 1		ISO	3	143,086,162	143,087,289	RGD:1624291	RGD
G	Id1	inhibitor of DNA binding 1		IEA	3	143,086,162	143,087,289	RGD:1600115	ENSEMBL
G	Lef1	lymphoid enhancer binding factor 1		ISO	2	228,550,263	228,673,131	RGD:1624291	RGD
G	Lef1	lymphoid enhancer binding factor 1		IEA	2	228,550,263	228,673,131	RGD:1600115	ENSEMBL
G	Lef1	lymphoid enhancer binding factor 1		IBA	2	228,550,263	228,673,131	RGD:1600115	RefGenome
G	LOC100360337	zinc finger protein 128-like		ISO	1	72,788,832	72,801,150	RGD:1624291	RGD
G	LOC100360337	zinc finger protein 128-like		IEA	1	72,788,832	72,801,150	RGD:1600115	ENSEMBL
G	LOC100910454	twisted gastrulation protein homolog 1-like		IEA				RGD:1600115	ENSEMBL
G	Mapk3	mitogen activated protein kinase 3		ISO	1	185,935,044	185,941,245	RGD:1624291	RGD
G	Msx1	msh homeobox 1		ISO	14	78,257,345	78,261,144	RGD:1624291	RGD
G	Msx1	msh homeobox 1		ISO	14	78,257,345	78,261,144	RGD:1624291	RGD
G	Msx2	msh homeobox 2		ISO	17	17,243,262	17,248,927	RGD:1624291	RGD
G	Msx2	msh homeobox 2		ISO	17	17,243,262	17,248,927	RGD:1624291	RGD
G	Myh6	myosin, heavy chain 6, cardiac muscle, alpha		ISO	15	33,044,506	33,068,098	RGD:1624291	RGD
G	Myh6	myosin, heavy chain 6, cardiac muscle, alpha		IEA	15	33,044,506	33,068,098	RGD:1600115	ENSEMBL
G	Nkx2-5	NK2 homeobox 5		ISO	10	16,606,183	16,608,952	RGD:1624291	RGD
G	Nkx2-5	NK2 homeobox 5		IEA	10	16,606,183	16,608,952	RGD:1600115	ENSEMBL
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		IEA	10	77,689,244	77,690,871	RGD:1600115	ENSEMBL
G	Rgma	RGM domain family, member A		ISO	1	128,547,399	128,591,304	RGD:1624291	RGD
G	Rgma	RGM domain family, member A		IEA	1	128,547,399	128,591,304	RGD:1600115	ENSEMBL
G	Ryr2	ryanodine receptor 2, cardiac		ISO	17	68,959,042	69,544,816	RGD:1624291	RGD
G	Scx	scleraxis		ISO	7	114,504,701	114,506,719	RGD:1624291	RGD
G	Scx	scleraxis		IEA	7	114,504,701	114,506,719	RGD:1600115	ENSEMBL
G	Smad1	SMAD family member 1		IMP	19	30,348,886	30,409,345	RGD:1643232	RGD
G	Smad1	SMAD family member 1		ISO	19	30,348,886	30,409,345	RGD:1624291	RGD
G	Smad1	SMAD family member 1		ISO	19	30,348,886	30,409,345	RGD:1624291	RGD
G	Smad1	SMAD family member 1		ISO	19	30,348,886	30,409,345	RGD:1624291	RGD
G	Smad1	SMAD family member 1		ISS	19	30,348,886	30,409,345	RGD:1600115	UniProtKB
G	Smad1	SMAD family member 1		ISO	19	30,348,886	30,409,345	RGD:1624291	RGD
G	Smad1	SMAD family member 1		ISO	19	30,348,886	30,409,345	RGD:1624291	RGD
G	Smad4	SMAD family member 4		ISO	18	70,432,705	70,461,541	RGD:1624291	RGD
G	Smad5	SMAD family member 5		ISO	17	13,814,164	13,824,358	RGD:1624291	RGD
G	Smad5	SMAD family member 5		ISO	17	13,814,164	13,824,358	RGD:1624291	RGD
G	Smad5	SMAD family member 5		ISS	17	13,814,164	13,824,358	RGD:1600115	UniProtKB
G	Smad9	SMAD family member 9		ISO	2	144,014,436	144,030,672	RGD:1624291	RGD
G	Smad9	SMAD family member 9		IEA	2	144,014,436	144,030,672	RGD:1600115	ENSEMBL
G	Smad9	SMAD family member 9		ISO	2	144,014,436	144,030,672	RGD:1624291	RGD
G	Smurf1	SMAD specific E3 ubiquitin protein ligase 1		IEA	12	9,950,304	10,042,391	RGD:1600115	ENSEMBL
G	Smurf1	SMAD specific E3 ubiquitin protein ligase 1		ISO	12	9,950,304	10,042,391	RGD:1624291	RGD
G	T	brachyury		ISO	1	46,937,223	46,944,988	RGD:1624291	RGD
G	T	brachyury		IEA	1	46,937,223	46,944,988	RGD:1600115	ENSEMBL
G	Tdgf1	teratocarcinoma-derived growth factor 1		ISO	8	115,341,587	115,346,871	RGD:1624291	RGD
G	Tgfbr3	transforming growth factor, beta receptor III		ISO	14	3,051,039	3,240,286	RGD:1624291	RGD
G	Tgfbr3	transforming growth factor, beta receptor III		IEA	14	3,051,039	3,240,286	RGD:1600115	ENSEMBL
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		ISO	9	104,694,731	104,729,090	RGD:1624291	RGD
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		IEA	9	104,694,731	104,729,090	RGD:1600115	ENSEMBL
G	Usp15	ubiquitin specific peptidase 15		ISO	7	62,871,167	62,961,405	RGD:1624291	RGD
G	Usp15	ubiquitin specific peptidase 15		ISS	7	62,871,167	62,961,405	RGD:1600115	UniProtKB
G	Usp9x	ubiquitin specific peptidase 9, X-linked		IEA	X	21,606,330	21,718,042	RGD:1600115	ENSEMBL
G	Usp9x	ubiquitin specific peptidase 9, X-linked		ISO	X	21,606,330	21,718,042	RGD:1624291	RGD
G	Zcchc12	zinc finger, CCHC domain containing 12		ISO	X	8,729,463	8,732,648	RGD:1624291	RGD
G	Zcchc12	zinc finger, CCHC domain containing 12		IEA	X	8,729,463	8,732,648	RGD:1600115	ENSEMBL
BMP signaling pathway involved in heart development
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Msx1	msh homeobox 1		ISO	14	78,257,345	78,261,144	RGD:1624291	RGD
G	Msx1	msh homeobox 1		IEA	14	78,257,345	78,261,144	RGD:1600115	ENSEMBL
G	Msx2	msh homeobox 2		ISO	17	17,243,262	17,248,927	RGD:1624291	RGD
G	Msx2	msh homeobox 2		IEA	17	17,243,262	17,248,927	RGD:1600115	ENSEMBL
BMP signaling pathway involved in heart induction
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		ISS	3	121,372,692	121,381,236	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
G	Pou5f1	POU class 5 homeobox 1		ISO				RGD:1624291	RGD
BMP signaling pathway involved in mesodermal cell fate specification
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Etv2	ets variant 2		ISO	1	85,684,698	85,686,914	RGD:1624291	RGD
G	Etv2	ets variant 2		IEA	1	85,684,698	85,686,914	RGD:1600115	ENSEMBL
BMP signaling pathway involved in nephric duct formation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
BMP signaling pathway involved in renal system segmentation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
BMP signaling pathway involved in spinal cord dorsal/ventral patterning
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Chrd	chordin		ISO	11	82,401,701	82,410,401	RGD:1624291	RGD
G	Chrd	chordin		IEA	11	82,401,701	82,410,401	RGD:1600115	ENSEMBL
BMP signaling pathway involved in ureter morphogenesis
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
negative regulation of BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmper	BMP-binding endothelial regulator		ISO	8	22,975,570	23,096,066	RGD:1624291	RGD
G	Cav1	caveolin 1, caveolae protein		ISO	4	42,956,102	42,989,057	RGD:1624291	RGD
G	Cav1	caveolin 1, caveolae protein		IEA	4	42,956,102	42,989,057	RGD:1600115	ENSEMBL
G	Cer1	cerberus 1, DAN family BMP antagonist		ISO	5	101,756,095	101,759,451	RGD:1624291	RGD
G	Cer1	cerberus 1, DAN family BMP antagonist		ISO	5	101,756,095	101,759,451	RGD:1624291	RGD
G	Chrd	chordin		ISO	11	82,401,701	82,410,401	RGD:1624291	RGD
G	Chrd	chordin		ISO	11	82,401,701	82,410,401	RGD:1624291	RGD
G	Chrd	chordin		ISO	11	82,401,701	82,410,401	RGD:1624291	RGD
G	Chrd	chordin		IEA	11	82,401,701	82,410,401	RGD:1600115	ENSEMBL
G	Chrd	chordin		IEA	11	82,401,701	82,410,401	RGD:1600115	ENSEMBL
G	Dand5	DAN domain family, member 5		ISO	19	24,989,652	24,995,307	RGD:1624291	RGD
G	Dand5	DAN domain family, member 5		IEA	19	24,989,652	24,995,307	RGD:1600115	ENSEMBL
G	Dkk1	dickkopf WNT signaling pathway inhibitor 1		ISO	1	234,392,743	234,396,426	RGD:1624291	RGD
G	Fstl3	follistatin-like 3 (secreted glycoprotein)		ISO	7	11,438,360	11,442,885	RGD:1624291	RGD
G	Fstl3	follistatin-like 3 (secreted glycoprotein)		ISO	7	11,438,360	11,442,885	RGD:1624291	RGD
G	Fstl3	follistatin-like 3 (secreted glycoprotein)		IEA	7	11,438,360	11,442,885	RGD:1600115	ENSEMBL
G	Fstl3	follistatin-like 3 (secreted glycoprotein)		IEA	7	11,438,360	11,442,885	RGD:1600115	ENSEMBL
G	Fzd1	frizzled family receptor 1		ISO	4	25,994,423	25,998,821	RGD:1624291	RGD
G	Fzd1	frizzled family receptor 1		IEA	4	25,994,423	25,998,821	RGD:1600115	ENSEMBL
G	Fzd1	frizzled family receptor 1		IBA	4	25,994,423	25,998,821	RGD:1600115	RefGenome
G	Grem1	gremlin 1		ISO	3	99,597,201	99,608,935	RGD:1624291	RGD
G	Grem1	gremlin 1		ISO	3	99,597,201	99,608,935	RGD:1624291	RGD
G	Grem1	gremlin 1		ISO	3	99,597,201	99,608,935	RGD:1624291	RGD
G	Grem1	gremlin 1		IEA	3	99,597,201	99,608,935	RGD:1600115	ENSEMBL
G	Grem1	gremlin 1		IEA	3	99,597,201	99,608,935	RGD:1600115	ENSEMBL
G	Hipk2	homeodomain interacting protein kinase 2		ISO	4	66,273,623	66,455,774	RGD:1624291	RGD
G	Htra1	HtrA serine peptidase 1		ISO	1	190,257,899	190,308,325	RGD:1624291	RGD
G	Htra1	HtrA serine peptidase 1		IEA	1	190,257,899	190,308,325	RGD:1600115	ENSEMBL
G	Htra3	HtrA serine peptidase 3		ISO	14	80,702,016	80,730,742	RGD:1624291	RGD
G	Htra3	HtrA serine peptidase 3		ISS	14	80,702,016	80,730,742	RGD:1600115	UniProtKB
G	Lemd3	LEM domain containing 3		IEA	7	60,232,118	60,281,459	RGD:1600115	ENSEMBL
G	Lemd3	LEM domain containing 3		ISO	7	60,232,118	60,281,459	RGD:1624291	RGD
G	LOC100910454	twisted gastrulation protein homolog 1-like		IEA				RGD:1600115	ENSEMBL
G	Nanog	Nanog homeobox		ISO	4	159,190,786	159,198,160	RGD:1624291	RGD
G	Nanog	Nanog homeobox		IEA	4	159,190,786	159,198,160	RGD:1600115	ENSEMBL
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Nog	noggin		IEA	10	77,689,244	77,690,871	RGD:1600115	ENSEMBL
G	Nog	noggin		ISS	10	77,689,244	77,690,871	RGD:1600115	UniProtKB
G	Notch1	notch 1		ISO	3	4,631,797	4,677,640	RGD:1624291	RGD
G	Notch1	notch 1		IEA	3	4,631,797	4,677,640	RGD:1600115	ENSEMBL
G	RGD1565591	similar to Ski protein		IBA	5	171,953,650	171,987,624	RGD:1600115	RefGenome
G	Sfrp1	secreted frizzled-related protein 1		ISO	16	73,030,458	73,067,304	RGD:1624291	RGD
G	Sfrp1	secreted frizzled-related protein 1		IEA	16	73,030,458	73,067,304	RGD:1600115	ENSEMBL
G	Sfrp2	secreted frizzled-related protein 2		IEA	2	175,479,320	175,486,865	RGD:1600115	ENSEMBL
G	Sfrp2	secreted frizzled-related protein 2		ISO	2	175,479,320	175,486,865	RGD:1624291	RGD
G	Skor1	SKI family transcriptional corepressor 1		IEA	8	67,287,385	67,298,047	RGD:1600115	ENSEMBL
G	Skor2	SKI family transcriptional corepressor 2		ISO	18	73,821,250	73,864,209	RGD:1624291	RGD
G	Smad6	SMAD family member 6		IEA	8	68,144,395	68,214,652	RGD:1600115	ENSEMBL
G	Smad6	SMAD family member 6		ISO	8	68,144,395	68,214,652	RGD:1624291	RGD
G	Smad7	SMAD family member 7		ISO	18	72,294,803	72,323,354	RGD:1624291	RGD
G	Smad7	SMAD family member 7		ISO	18	72,294,803	72,323,354	RGD:1624291	RGD
G	Smad7	SMAD family member 7		IEA	18	72,294,803	72,323,354	RGD:1600115	ENSEMBL
G	Smad7	SMAD family member 7		IEA	18	72,294,803	72,323,354	RGD:1600115	ENSEMBL
G	Sost	sclerostin		ISO	10	91,023,712	91,026,759	RGD:1624291	RGD
G	Sost	sclerostin		ISO	10	91,023,712	91,026,759	RGD:1624291	RGD
G	Sost	sclerostin		IEA	10	91,023,712	91,026,759	RGD:1600115	ENSEMBL
G	Sostdc1	sclerostin domain containing 1		ISO	6	55,066,277	55,070,451	RGD:1624291	RGD
G	Sostdc1	sclerostin domain containing 1		ISO	6	55,066,277	55,070,451	RGD:1624291	RGD
G	Sostdc1	sclerostin domain containing 1		IEA	6	55,066,277	55,070,451	RGD:1600115	ENSEMBL
G	Spg20	spastic paraplegia 20 (Troyer syndrome)		ISO	2	144,335,236	144,362,246	RGD:1624291	RGD
G	Tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)		ISO	1	262,031,823	262,226,710	RGD:1624291	RGD
G	Tob1	transducer of ErbB-2.1		ISO	10	82,852,405	82,854,443	RGD:1624291	RGD
G	Trim33	tripartite motif-containing 33		ISO	2	198,525,829	198,603,543	RGD:1624291	RGD
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		ISO	9	104,694,731	104,729,090	RGD:1624291	RGD
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		ISO	9	104,694,731	104,729,090	RGD:1624291	RGD
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		IEA	9	104,694,731	104,729,090	RGD:1600115	ENSEMBL
G	Vwc2	von Willebrand factor C domain containing 2		ISO				RGD:1624291	RGD
G	Vwc2l	von Willebrand factor C domain-containing protein 2-like		ISO	9	69,738,883	69,944,712	RGD:1624291	RGD
G	Vwc2l	von Willebrand factor C domain-containing protein 2-like		IEA	9	69,738,883	69,944,712	RGD:1600115	ENSEMBL
G	Wnt1	wingless-type MMTV integration site family, member 1		ISO	7	137,557,836	137,561,883	RGD:1624291	RGD
G	Wnt5a	wingless-type MMTV integration site family, member 5A		ISO	16	3,782,025	3,799,625	RGD:1624291	RGD
G	Wnt5a	wingless-type MMTV integration site family, member 5A		IEA	16	3,782,025	3,799,625	RGD:1600115	ENSEMBL
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
positive regulation of BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acvrl1	activin A receptor type II-like 1		ISO	7	139,873,596	139,884,675	RGD:1624291	RGD
G	Acvrl1	activin A receptor type II-like 1		ISO	7	139,873,596	139,884,675	RGD:1624291	RGD
G	Acvrl1	activin A receptor type II-like 1		IEA	7	139,873,596	139,884,675	RGD:1600115	ENSEMBL
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
G	Bmpr2	bone morphogenetic protein receptor, type II (serine/threonine kinase)		ISO	9	58,327,587	58,436,057	RGD:1624291	RGD
G	Cyr61	cysteine-rich, angiogenic inducer, 61		ISO	2	243,824,303	243,827,262	RGD:1624291	RGD
G	Cyr61	cysteine-rich, angiogenic inducer, 61		IEA	2	243,824,303	243,827,262	RGD:1600115	ENSEMBL
G	Eng	endoglin		ISO				RGD:1624291	RGD
G	Fbxl15	F-box and leucine-rich repeat protein 15		ISS	1	251,544,341	251,546,582	RGD:1600115	UniProtKB
G	Fbxl15	F-box and leucine-rich repeat protein 15		ISO	1	251,544,341	251,546,582	RGD:1624291	RGD
G	Fkbp8	FK506 binding protein 8		ISO	16	19,401,883	19,407,192	RGD:1624291	RGD
G	Fkbp8	FK506 binding protein 8		IEA	16	19,401,883	19,407,192	RGD:1600115	ENSEMBL
G	Foxd1	forkhead box D1		ISO	2	28,944,067	28,945,665	RGD:1624291	RGD
G	Foxd1	forkhead box D1		ISS	2	28,944,067	28,945,665	RGD:1600115	UniProtKB
G	Foxd1	forkhead box D1		IBA	2	28,944,067	28,945,665	RGD:1600115	RefGenome
G	Foxd2	forkhead box D2		IBA	5	135,269,120	135,270,809	RGD:1600115	RefGenome
G	Foxd4	forkhead box D4		IBA	1	228,348,202	228,349,654	RGD:1600115	RefGenome
G	Gata4	GATA binding protein 4		IDA	15	42,472,793	42,519,569		BHF-UCL
G	Gata6	GATA binding protein 6		IDA	18	2,504,264	2,534,648		BHF-UCL
G	Gdf2	growth differentiation factor 2		ISO				RGD:1624291	RGD
G	Gpc3	glypican 3		ISO	X	139,192,115	139,560,649	RGD:1624291	RGD
G	Hes1	hairy and enhancer of split 1 (Drosophila)		ISO	11	72,603,482	72,605,673	RGD:1624291	RGD
G	Hes5	hairy and enhancer of split 5 (Drosophila)		ISO	5	171,763,869	171,764,636	RGD:1624291	RGD
G	Hes5	hairy and enhancer of split 5 (Drosophila)		ISS	5	171,763,869	171,764,636	RGD:1600115	UniProtKB
G	Ilk	integrin-linked kinase		ISO	1	163,481,299	163,487,550	RGD:1624291	RGD
G	Ilk	integrin-linked kinase		IEA	1	163,481,299	163,487,550	RGD:1600115	ENSEMBL
G	Kcp	kielin/chordin-like protein		ISO	4	56,362,648	56,389,182	RGD:1624291	RGD
G	Kcp	kielin/chordin-like protein		IEA	4	56,362,648	56,389,182	RGD:1600115	ENSEMBL
G	Kdr	kinase insert domain receptor		ISO				RGD:1624291	RGD
G	LOC100910454	twisted gastrulation protein homolog 1-like		IEA				RGD:1600115	ENSEMBL
G	Msx1	msh homeobox 1		ISO	14	78,257,345	78,261,144	RGD:1624291	RGD
G	Msx1	msh homeobox 1		IEA	14	78,257,345	78,261,144	RGD:1600115	ENSEMBL
G	Msx2	msh homeobox 2		ISO	17	17,243,262	17,248,927	RGD:1624291	RGD
G	Msx2	msh homeobox 2		IEA	17	17,243,262	17,248,927	RGD:1600115	ENSEMBL
G	Notch1	notch 1		ISO	3	4,631,797	4,677,640	RGD:1624291	RGD
G	Notch1	notch 1		IEA	3	4,631,797	4,677,640	RGD:1600115	ENSEMBL
G	Notch1	notch 1		ISS	3	4,631,797	4,677,640	RGD:1600115	UniProtKB
G	Rbpj	recombination signal binding protein for immunoglobulin kappa J region		ISO				RGD:1624291	RGD
G	Smad2	SMAD family member 2		ISO	18	73,180,520	73,241,707	RGD:1624291	RGD
G	Smad2	SMAD family member 2		IEA	18	73,180,520	73,241,707	RGD:1600115	ENSEMBL
G	Smad4	SMAD family member 4		ISO	18	70,432,705	70,461,541	RGD:1624291	RGD
G	Sox11	SRY (sex determining region Y)-box 11		ISO	6	45,141,366	45,143,387	RGD:1624291	RGD
G	Sox11	SRY (sex determining region Y)-box 11		ISS	6	45,141,366	45,143,387	RGD:1600115	UniProtKB
G	Sulf1	sulfatase 1		IEA	5	5,582,896	5,748,106	RGD:1600115	ENSEMBL
G	Sulf1	sulfatase 1		ISO	5	5,582,896	5,748,106	RGD:1624291	RGD
G	Sulf1	sulfatase 1		ISS	5	5,582,896	5,748,106	RGD:1600115	UniProtKB
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		ISO	9	104,694,731	104,729,090	RGD:1624291	RGD
G	Twsg1	twisted gastrulation homolog 1 (Drosophila)		IEA	9	104,694,731	104,729,090	RGD:1600115	ENSEMBL
G	Zfp423	zinc finger protein 423		ISO	19	20,475,864	20,739,236	RGD:1624291	RGD
G	Zfp423	zinc finger protein 423		IEA	19	20,475,864	20,739,236	RGD:1600115	ENSEMBL
G	Zfp423	zinc finger protein 423		ISS	19	20,475,864	20,739,236	RGD:1600115	UniProtKB
positive regulation of Wnt receptor signaling pathway by BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp2	bone morphogenetic protein 2		ISO	3	121,372,692	121,381,236	RGD:1624291	RGD
G	Bmp2	bone morphogenetic protein 2		IEA	3	121,372,692	121,381,236	RGD:1600115	ENSEMBL
regulation of BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acvr2a	activin A receptor, type IIA		ISO	3	29,779,827	29,808,881	RGD:1624291	RGD
G	Fkbp8	FK506 binding protein 8		ISO	16	19,401,883	19,407,192	RGD:1624291	RGD
G	Hoxa13	homeo box A13		ISO	4	80,558,841	80,561,053	RGD:1624291	RGD
G	Nog	noggin		ISO	10	77,689,244	77,690,871	RGD:1624291	RGD
G	Rgma	RGM domain family, member A		ISO	1	128,547,399	128,591,304	RGD:1624291	RGD
G	Rgma	RGM domain family, member A		IEA	1	128,547,399	128,591,304	RGD:1600115	ENSEMBL
G	Tfap2b	transcription factor AP-2 beta		ISO	9	18,052,402	18,082,202	RGD:1624291	RGD
G	Tfap2b	transcription factor AP-2 beta		ISS	9	18,052,402	18,082,202	RGD:1600115	UniProtKB
sequestering of BMP in extracellular matrix
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Cer1	cerberus 1, DAN family BMP antagonist		ISO	5	101,756,095	101,759,451	RGD:1624291	RGD
G	Cer1	cerberus 1, DAN family BMP antagonist		IEA	5	101,756,095	101,759,451	RGD:1600115	ENSEMBL
G	Cer1	cerberus 1, DAN family BMP antagonist		ISO	5	101,756,095	101,759,451	RGD:1624291	RGD
G	Fbn1	fibrillin 1		ISO	3	112,608,480	112,804,118	RGD:1624291	RGD
G	Nbl1	neuroblastoma 1, DAN family BMP antagonist		ISO				RGD:1624291	RGD
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL

Term paths to the root

Path 1
Term	Annotations
biological_process	136531
metabolic process	36512
regulation of metabolic process	16743
regulation of macromolecule metabolic process	13752
regulation of gene expression	9589
regulation of transcription, DNA-dependent	7718
regulation of transcription from RNA polymerase II promoter	4055
BMP signaling pathway	319
BMP signaling pathway involved in Malpighian tubule cell chemotaxis	0
BMP signaling pathway involved in determination of left/right symmetry +	0
BMP signaling pathway involved in forebrain neuron fate commitment	0
BMP signaling pathway involved in growth plate cartilage chondrocyte development	0
BMP signaling pathway involved in heart development +	10
BMP signaling pathway involved in mesodermal cell fate specification	2
BMP signaling pathway involved in nephric duct formation	3
BMP signaling pathway involved in renal system segmentation	3
BMP signaling pathway involved in spinal cord dorsal/ventral patterning +	2
BMP signaling pathway involved in ureter morphogenesis	3
negative regulation of BMP signaling pathway +	85
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	4
positive regulation of BMP signaling pathway	53
positive regulation of Wnt receptor signaling pathway by BMP signaling pathway	2
regulation of BMP signaling pathway +	146
regulation of hair cycle by BMP signaling pathway	0
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	4
Path 2
Term	Annotations
biological_process	136531
metabolic process	36512
cellular metabolic process	30527
cellular aromatic compound metabolic process	15094
nucleobase-containing compound metabolic process	14486
nucleic acid metabolic process	12512
RNA metabolic process	10231
RNA biosynthetic process	8851
transcription, DNA-dependent	8783
regulation of transcription, DNA-dependent	7718
regulation of transcription from RNA polymerase II promoter	4055
BMP signaling pathway	319
BMP signaling pathway involved in Malpighian tubule cell chemotaxis	0
BMP signaling pathway involved in determination of left/right symmetry +	0
BMP signaling pathway involved in forebrain neuron fate commitment	0
BMP signaling pathway involved in growth plate cartilage chondrocyte development	0
BMP signaling pathway involved in heart development +	10
BMP signaling pathway involved in mesodermal cell fate specification	2
BMP signaling pathway involved in nephric duct formation	3
BMP signaling pathway involved in renal system segmentation	3
BMP signaling pathway involved in spinal cord dorsal/ventral patterning +	2
BMP signaling pathway involved in ureter morphogenesis	3
negative regulation of BMP signaling pathway +	85
negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	4
positive regulation of BMP signaling pathway	53
positive regulation of Wnt receptor signaling pathway by BMP signaling pathway	2
regulation of BMP signaling pathway +	146
regulation of hair cycle by BMP signaling pathway	0
specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	4