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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation


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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:4052628) RGD PMID:4052628 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Kng1 kininogen 1 involved_in ISO
IBA		 (PMID:11970955)
GO_REF:0000033		 RGD
GO_Central		 PMID:11970955 GO_REF:0000033 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Kng1_v1 kininogen 1, variant 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118
G Kng2 kininogen 2 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within
involved_in		 IDA
ISO
IBA
IEA		 MGI:2183063 (PMID:9616155), (PMID:9788960)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:9616155 PMID:9788960 PMID:1440533 GO_REF:0000033 GO_REF:0000118, RGD:11100042 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IDA
ISO		 PMID:17379830
(PMID:17379830)		 RGD PMID:17379830 PMID:17379830 RGD:8553298 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356 		JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3028929 (PMID:14702107)		 Ensembl
RGD		 PMID:14702107 GO_REF:0000107 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11848438 GO_REF:0000033, RGD:632532 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G F2 coagulation factor II, thrombin involved_in ISO
IEA		 (PMID:12855810)
GO_REF:0000107		 RGD
Ensembl		 PMID:12855810 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
IEA		 (PMID:16846481)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:16846481 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fgl1 fibrinogen-like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000043
MGI:3789962 (PMID:15869579)		 UniProt
RGD		 PMID:15869579 GO_REF:0000043 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrg l1 histidine-rich glycoprotein like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
(PMID:9733098)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:9733098 GO_REF:0000033 GO_REF:0000118 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plg plasminogen involved_in ISO
IEA		 (PMID:14688145), (PMID:17307854), (PMID:22025510)
GO_REF:0000104		 RGD
UniProt		 PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286 		JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
MGI:3789962 (PMID:15869579)
GO_REF:0000118		 GO_Central
RGD
TreeGrafter		 PMID:15869579 GO_REF:0000033 GO_REF:0000118 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrg l1 histidine-rich glycoprotein like 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000118		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA		 (PMID:2503541)
GO_REF:0000107		 RGD
Ensembl		 PMID:2503541 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO		 (PMID:134998) RGD PMID:134998 PMID:6506034 RGD:1625541 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:8995232)		 Ensembl
RGD		 PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (PMID:10557321), (PMID:11435305) RGD PMID:10557321 PMID:11435305 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IEA
ISS		 (PMID:2538439)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA		 (PMID:2538439)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:8188664)		 UniProt
Ensembl
RGD		 PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (PMID:19855083) RGD PMID:19855083 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (PMID:19218546) RGD PMID:19218546 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO		 GO_REF:0000024
(MGI:1202206|PMID:9501222)		 UniProt
RGD		 PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16195328)		 Ensembl
RGD		 PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18541721)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18541721 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3835235|PMID:19008452)		 UniProt
RGD		 PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3813784|PMID:16940418)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16940418 GO_REF:0000024 GO_REF:0000107 MGI:3813784 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4418017|PMID:19855083)		 Ensembl
RGD		 PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in ISO UniProtKB:P35951 (MGI:5905608|PMID:27430239) RGD PMID:27430239 MGI:5905608 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in ISO (PMID:30425049)
(MGI:6284734|PMID:30425049)		 RGD PMID:30425049 MGI:6284734 NCBI chr 6:88,960,691...88,971,744
Ensembl chr 6:88,960,695...88,971,301 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (PMID:20585042) RGD PMID:20585042 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201 		JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO		 GO_REF:0000107
(PMID:89876)		 Ensembl
RGD		 PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786 		JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20292
    negative regulation of biological process 5757
      negative regulation of hemostasis 47
        negative regulation of blood coagulation 46
          fibrinolysis + 21
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 16
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 20292
    biological regulation 13633
      regulation of biological process 13220
        regulation of response to stimulus 4219
          regulation of response to stress 1437
            regulation of response to wounding 187
              regulation of wound healing 139
                regulation of blood coagulation 66
                  negative regulation of blood coagulation 46
                    fibrinolysis + 21
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 16
                    positive regulation of fibrinolysis 4
paths to the root