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Term:cytokine-mediated signaling pathway
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Accession:GO:0019221 term browser browse the term
Definition:A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: cytokine and chemokine mediated signaling pathway;   cytokine mediated signalling pathway
 xref_analog: Reactome:REACT_25229

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cytokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G AAAS achalasia, adrenocortical insufficiency, alacrimia GBrowse link TAS 12 53,701,240 53,715,412 RGD:2290271 Reactome
G ADAR adenosine deaminase, RNA-specific GBrowse link TAS 1 154,554,533 154,600,456 RGD:2290271 Reactome
G ARIH1 ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) GBrowse link TAS 15 72,766,667 72,878,896 RGD:2290271 Reactome
G B2M beta-2-microglobulin GBrowse link TAS 15 45,003,685 45,010,357 RGD:2290271 Reactome
G BAD BCL2-associated agonist of cell death GBrowse link IEA 11 64,037,300 64,052,176 RGD:2290271 ENSEMBL
G CAMK2A calcium/calmodulin-dependent protein kinase II alpha GBrowse link TAS 5 149,599,054 149,669,403 RGD:2290271 Reactome
G CAMK2B calcium/calmodulin-dependent protein kinase II beta GBrowse link TAS 7 44,256,749 44,365,230 RGD:2290271 Reactome
G CAMK2D calcium/calmodulin-dependent protein kinase II delta GBrowse link TAS 4 114,372,188 114,683,083 RGD:2290271 Reactome
G CAMK2G calcium/calmodulin-dependent protein kinase II gamma GBrowse link TAS 10 75,572,259 75,634,349 RGD:2290271 Reactome
G CCL2 chemokine (C-C motif) ligand 2 GBrowse link IDA 17 32,582,296 32,584,222 RGD:2290271 BHF-UCL
G CCR1 chemokine (C-C motif) receptor 1 GBrowse link NAS 3 46,243,200 46,249,832 RGD:2290271 UniProtKB
G CCR2 chemokine (C-C motif) receptor 2 GBrowse link IDA 3 46,395,235 46,402,413 RGD:2290271 MGI
G CD44 CD44 molecule (Indian blood group) GBrowse link TAS 11 35,160,417 35,253,949 RGD:2290271 Reactome
G CEBPA CCAAT/enhancer binding protein (C/EBP), alpha GBrowse link NAS 19 33,790,840 33,793,430 RGD:2290271 UniProtKB
G CIITA class II, major histocompatibility complex, transactivator GBrowse link TAS 16 10,971,055 11,018,840 RGD:2290271 Reactome
G CLCF1 cardiotrophin-like cytokine factor 1 GBrowse link NAS 11 67,131,639 67,141,648 RGD:2290271 UniProtKB
G CSF1R colony stimulating factor 1 receptor GBrowse link IMP 5 149,432,854 149,492,935 RGD:2290271 UniProtKB
G CSF3 colony stimulating factor 3 (granulocyte) GBrowse link NAS 17 38,171,614 38,174,066 RGD:2290271 UniProtKB
G CX3CL1 chemokine (C-X3-C motif) ligand 1 GBrowse link TAS 16 57,406,414 57,418,956 RGD:2290271 UniProtKB
G CX3CL1 chemokine (C-X3-C motif) ligand 1 GBrowse link IEA 16 57,406,414 57,418,956 RGD:2290271 ENSEMBL
G DUOX1 dual oxidase 1 GBrowse link IDA 15 45,422,192 45,457,774 RGD:2290271 UniProtKB
G DUOX2 dual oxidase 2 GBrowse link ISS 15 45,384,852 45,406,359 RGD:2290271 UniProtKB
G DUOX2 dual oxidase 2 GBrowse link IDA 15 45,384,852 45,406,359 RGD:2290271 UniProtKB
G EBI3 Epstein-Barr virus induced 3 GBrowse link IPI 19 4,229,540 4,237,525 RGD:2290271 GOC
G EDN2 endothelin 2 GBrowse link IDA 1 41,944,446 41,950,344 RGD:2290271 BHF-UCL
G EGR1 early growth response 1 GBrowse link TAS 5 137,801,181 137,805,004 RGD:2290271 Reactome
G EIF4A1 eukaryotic translation initiation factor 4A1 GBrowse link TAS 17 7,476,024 7,482,324 RGD:2290271 Reactome
G EIF4A2 eukaryotic translation initiation factor 4A2 GBrowse link TAS 3 186,501,361 186,507,686 RGD:2290271 Reactome
G EIF4A3 eukaryotic translation initiation factor 4A3 GBrowse link TAS 17 78,109,013 78,120,982 RGD:2290271 Reactome
G EIF4E eukaryotic translation initiation factor 4E GBrowse link TAS 4 99,799,607 99,851,786 RGD:2290271 Reactome
G EIF4E2 eukaryotic translation initiation factor 4E family member 2 GBrowse link TAS 2 233,415,357 233,433,920 RGD:2290271 Reactome
G EIF4E3 eukaryotic translation initiation factor 4E family member 3 GBrowse link TAS 3 71,728,440 71,803,924 RGD:2290271 Reactome
G EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 GBrowse link TAS 3 184,032,283 184,053,146 RGD:2290271 Reactome
G EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 GBrowse link TAS 11 10,818,593 10,830,582 RGD:2290271 Reactome
G EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 GBrowse link TAS 1 21,132,785 21,503,381 RGD:2290271 Reactome
G EREG epiregulin GBrowse link IDA 4 75,230,860 75,254,477 RGD:2290271 UniProtKB
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) GBrowse link TAS 1 149,754,250 149,764,074 RGD:2290271 Reactome
G FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) GBrowse link TAS 1 120,926,128 120,935,944 RGD:2290271 Reactome
G FER fer (fps/fes related) tyrosine kinase GBrowse link IMP 5 108,083,523 108,523,373 RGD:2290271 UniProtKB
G FLNB filamin B, beta GBrowse link TAS 3 57,994,127 58,157,982 RGD:2290271 Reactome
G FLT3 fms-related tyrosine kinase 3 GBrowse link ISS 13 28,577,411 28,674,729 RGD:2290271 UniProtKB
G GBP1 guanylate binding protein 1, interferon-inducible GBrowse link TAS 1 89,517,987 89,531,043 RGD:2290271 Reactome
G GBP2 guanylate binding protein 2, interferon-inducible GBrowse link TAS 1 89,573,310 89,591,799 RGD:2290271 Reactome
G HCK hemopoietic cell kinase GBrowse link TAS 20 30,639,991 30,689,659 RGD:2290271 UniProtKB
G HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 GBrowse link TAS 4 89,378,268 89,427,321 RGD:2290271 Reactome
G HLA-A major histocompatibility complex, class I, A GBrowse link TAS 6 29,910,247 29,913,661 RGD:2290271 Reactome
G HLA-B major histocompatibility complex, class I, B GBrowse link TAS 6 31,321,649 31,324,989 RGD:2290271 Reactome
G HLA-C major histocompatibility complex, class I, C GBrowse link TAS 6 31,236,526 31,239,913 RGD:2290271 Reactome
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 GBrowse link TAS 6 33,032,346 33,048,555 RGD:2290271 Reactome
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 GBrowse link TAS 6 33,043,703 33,057,473 RGD:2290271 Reactome
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 GBrowse link TAS 6 32,605,183 32,611,429 RGD:2290271 Reactome
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 GBrowse link TAS 6 32,709,163 32,714,664 RGD:2290271 Reactome
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 GBrowse link TAS 6 32,627,241 32,634,466 RGD:2290271 Reactome
G HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 GBrowse link TAS 6 32,723,875 32,731,330 RGD:2290271 Reactome
G HLA-DRA major histocompatibility complex, class II, DR alpha GBrowse link TAS 6 32,407,619 32,412,823 RGD:2290271 Reactome
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 GBrowse link TAS 6 32,546,546 32,557,613 RGD:2290271 Reactome
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 TAS RGD:2290271 Reactome
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 TAS RGD:2290271 Reactome
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 GBrowse link TAS 6 32,485,151 32,498,006 RGD:2290271 Reactome
G HLA-E major histocompatibility complex, class I, E GBrowse link TAS 6 30,457,183 30,461,982 RGD:2290271 Reactome
G HLA-F major histocompatibility complex, class I, F GBrowse link TAS 6 29,691,117 29,695,073 RGD:2290271 Reactome
G HLA-G major histocompatibility complex, class I, G GBrowse link TAS 6 29,794,756 29,798,899 RGD:2290271 Reactome
G ICAM1 intercellular adhesion molecule 1 GBrowse link TAS 19 10,381,517 10,397,291 RGD:2290271 Reactome
G IFI27 interferon, alpha-inducible protein 27 GBrowse link TAS 14 94,577,079 94,583,033 RGD:2290271 Reactome
G IFI30 interferon, gamma-inducible protein 30 GBrowse link TAS 19 18,284,579 18,288,927 RGD:2290271 Reactome
G IFI35 interferon-induced protein 35 GBrowse link TAS 17 41,158,742 41,166,476 RGD:2290271 Reactome
G IFI6 interferon, alpha-inducible protein 6 GBrowse link TAS 1 27,992,572 27,998,724 RGD:2290271 Reactome
G IFIT1 interferon-induced protein with tetratricopeptide repeats 1 GBrowse link TAS 10 91,152,303 91,166,244 RGD:2290271 Reactome
G IFIT2 interferon-induced protein with tetratricopeptide repeats 2 GBrowse link TAS 10 91,061,706 91,069,033 RGD:2290271 Reactome
G IFIT3 interferon-induced protein with tetratricopeptide repeats 3 GBrowse link TAS 10 91,087,602 91,100,725 RGD:2290271 Reactome
G IFITM1 interferon induced transmembrane protein 1 GBrowse link TAS 11 313,991 315,272 RGD:2290271 Reactome
G IFITM2 interferon induced transmembrane protein 2 GBrowse link TAS 11 308,107 309,410 RGD:2290271 Reactome
G IFITM3 interferon induced transmembrane protein 3 GBrowse link TAS 11 319,673 320,914 RGD:2290271 Reactome
G IFNA1 interferon, alpha 1 GBrowse link TAS 9 21,440,453 21,441,315 RGD:2290271 Reactome
G IFNA10 interferon, alpha 10 GBrowse link TAS 9 21,206,180 21,207,142 RGD:2290271 Reactome
G IFNA13 interferon, alpha 13 GBrowse link TAS 9 21,367,371 21,368,075 RGD:2290271 Reactome
G IFNA14 interferon, alpha 14 GBrowse link TAS 9 21,239,201 21,239,978 RGD:2290271 Reactome
G IFNA16 interferon, alpha 16 GBrowse link TAS 9 21,216,372 21,217,310 RGD:2290271 Reactome
G IFNA17 interferon, alpha 17 GBrowse link TAS 9 21,227,242 21,228,221 RGD:2290271 Reactome
G IFNA2 interferon, alpha 2 GBrowse link TAS 9 21,384,254 21,385,396 RGD:2290271 Reactome
G IFNA21 interferon, alpha 21 GBrowse link TAS 9 21,165,636 21,166,659 RGD:2290271 Reactome
G IFNA4 interferon, alpha 4 GBrowse link TAS 9 21,186,617 21,187,598 RGD:2290271 Reactome
G IFNA5 interferon, alpha 5 GBrowse link TAS 9 21,304,613 21,305,312 RGD:2290271 Reactome
G IFNA6 interferon, alpha 6 GBrowse link TAS 9 21,350,317 21,350,886 RGD:2290271 Reactome
G IFNA7 interferon, alpha 7 GBrowse link TAS 9 21,201,468 21,202,204 RGD:2290271 Reactome
G IFNA8 interferon, alpha 8 GBrowse link TAS 9 21,409,146 21,410,184 RGD:2290271 Reactome
G IFNAR1 interferon (alpha, beta and omega) receptor 1 GBrowse link TAS 21 34,697,214 34,732,129 RGD:2290271 Reactome
G IFNAR2 interferon (alpha, beta and omega) receptor 2 GBrowse link TAS 21 34,602,231 34,636,827 RGD:2290271 Reactome
G IFNB1 interferon, beta 1, fibroblast GBrowse link TAS 9 21,077,104 21,077,943 RGD:2290271 Reactome
G IFNG interferon, gamma GBrowse link TAS 12 68,548,550 68,553,521 RGD:2290271 Reactome
G IFNGR1 interferon gamma receptor 1 GBrowse link TAS 6 137,518,621 137,540,567 RGD:2290271 Reactome
G IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) GBrowse link TAS 21 34,775,202 34,809,828 RGD:2290271 Reactome
G IFNK interferon, kappa GBrowse link IDA 9 27,524,312 27,526,496 RGD:2290271 UniProtKB
G IFNLR1 interferon, lambda receptor 1 GBrowse link NAS 1 24,480,647 24,513,765 RGD:2290271 GOC
G IL12RB1 interleukin 12 receptor, beta 1 GBrowse link TAS 19 18,170,371 18,197,697 RGD:2290271 BHF-UCL
G IL12RB2 interleukin 12 receptor, beta 2 GBrowse link TAS 1 67,773,047 67,862,583 RGD:2290271 GOC
G IL13RA2 interleukin 13 receptor, alpha 2 GBrowse link TAS X 114,238,538 114,252,207 RGD:2290271 GOC
G IL15RA interleukin 15 receptor, alpha GBrowse link TAS 10 5,994,334 6,020,150 RGD:2290271 GOC
G IL17RB interleukin 17 receptor B GBrowse link NAS 3 53,880,577 53,899,827 RGD:2290271 GOC
G IL1A interleukin 1, alpha GBrowse link IMP 2 113,531,492 113,542,971 RGD:2290271 BHF-UCL
G IL1B interleukin 1, beta GBrowse link IDA 2 113,587,337 113,594,356 RGD:2290271 BHF-UCL
G IL2RB interleukin 2 receptor, beta GBrowse link IDA 22 37,521,878 37,545,962 RGD:2290271 MGI
G IL31RA interleukin 31 receptor A GBrowse link TAS 5 55,147,207 55,218,682 RGD:2290271 UniProtKB
G IL5 interleukin 5 (colony-stimulating factor, eosinophil) GBrowse link IEA 5 131,877,136 131,879,214 RGD:2290271 ENSEMBL
G IL6 interleukin 6 (interferon, beta 2) GBrowse link IDA 7 22,766,766 22,771,621 RGD:2290271 BHF-UCL
G IL6 interleukin 6 (interferon, beta 2) GBrowse link IDA 7 22,766,766 22,771,621 RGD:2290271 BHF-UCL
G IL6R interleukin 6 receptor GBrowse link IDA 1 154,377,669 154,441,926 RGD:2290271 BHF-UCL
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IDA 5 55,230,923 55,290,821 RGD:2290271 BHF-UCL
G IP6K2 inositol hexakisphosphate kinase 2 GBrowse link TAS 3 48,725,436 48,754,711 RGD:2290271 Reactome
G IRAK3 interleukin-1 receptor-associated kinase 3 GBrowse link ISS 12 66,582,978 66,648,402 RGD:2290271 UniProtKB
G IRAK4 interleukin-1 receptor-associated kinase 4 GBrowse link IEA 12 44,152,747 44,183,346 RGD:2290271 ENSEMBL
G IRAK4 interleukin-1 receptor-associated kinase 4 GBrowse link IEA 12 44,152,747 44,183,346 RGD:2290271 ENSEMBL
G IRF1 interferon regulatory factor 1 GBrowse link TAS 5 131,817,301 131,826,465 RGD:2290271 Reactome
G IRF2 interferon regulatory factor 2 GBrowse link TAS 4 185,308,876 185,395,726 RGD:2290271 Reactome
G IRF3 interferon regulatory factor 3 GBrowse link TAS 19 50,162,826 50,169,132 RGD:2290271 Reactome
G IRF4 interferon regulatory factor 4 GBrowse link TAS 6 391,739 411,443 RGD:2290271 Reactome
G IRF5 interferon regulatory factor 5 GBrowse link TAS 7 128,577,994 128,590,089 RGD:2290271 Reactome
G IRF6 interferon regulatory factor 6 GBrowse link TAS 1 209,958,968 209,979,520 RGD:2290271 Reactome
G IRF7 interferon regulatory factor 7 GBrowse link TAS 11 612,555 615,999 RGD:2290271 Reactome
G IRF8 interferon regulatory factor 8 GBrowse link TAS 16 85,932,774 85,956,212 RGD:2290271 Reactome
G IRF9 interferon regulatory factor 9 GBrowse link TAS 14 24,630,422 24,635,774 RGD:2290271 Reactome
G ISG15 ISG15 ubiquitin-like modifier GBrowse link TAS 1 948,847 949,920 RGD:2290271 Reactome
G ISG20 interferon stimulated exonuclease gene 20kDa GBrowse link TAS 15 89,182,039 89,198,879 RGD:2290271 Reactome
G JAK1 Janus kinase 1 GBrowse link TAS 1 65,298,906 65,432,187 RGD:2290271 Reactome
G JAK2 Janus kinase 2 GBrowse link ISS 9 4,985,245 5,128,183 RGD:2290271 UniProtKB
G JAK2 Janus kinase 2 GBrowse link IDA 9 4,985,245 5,128,183 RGD:2290271 BHF-UCL
G JAK2 Janus kinase 2 GBrowse link TAS 9 4,985,245 5,128,183 RGD:2290271 Reactome
G KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link IDA 4 55,524,095 55,606,881 RGD:2290271 UniProtKB
G KLF6 Kruppel-like factor 6 GBrowse link IEA 10 3,818,188 3,827,473 RGD:2290271 ENSEMBL
G KPNA1 karyopherin alpha 1 (importin alpha 5) GBrowse link TAS 3 122,140,748 122,233,786 RGD:2290271 Reactome
G KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) GBrowse link TAS 17 66,031,848 66,042,970 RGD:2290271 Reactome
G KPNA3 karyopherin alpha 3 (importin alpha 4) GBrowse link TAS 13 50,273,443 50,367,057 RGD:2290271 Reactome
G KPNA4 karyopherin alpha 4 (importin alpha 3) GBrowse link TAS 3 160,212,783 160,283,376 RGD:2290271 Reactome
G KPNA5 karyopherin alpha 5 (importin alpha 6) GBrowse link TAS 6 117,002,367 117,063,030 RGD:2290271 Reactome
G KPNA7 karyopherin alpha 7 (importin alpha 8) GBrowse link TAS 7 98,771,197 98,805,089 RGD:2290271 Reactome
G KPNB1 karyopherin (importin) beta 1 GBrowse link TAS 17 45,727,275 45,761,004 RGD:2290271 Reactome
G KRAS v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog GBrowse link IEA 12 25,358,180 25,403,854 RGD:2290271 ENSEMBL
G LIFR leukemia inhibitory factor receptor alpha GBrowse link IDA 5 38,475,065 38,595,507 RGD:2290271 MGI
G LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor GBrowse link NAS 1 53,708,036 53,793,821 RGD:2290271 UniProtKB
G MAPK3 mitogen-activated protein kinase 3 GBrowse link TAS 16 30,125,426 30,134,630 RGD:2290271 Reactome
G MT2A metallothionein 2A GBrowse link TAS 16 56,642,478 56,643,409 RGD:2290271 Reactome
G MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) GBrowse link TAS 21 42,792,520 42,831,141 RGD:2290271 Reactome
G MX2 myxovirus (influenza virus) resistance 2 (mouse) GBrowse link TAS 21 42,733,950 42,780,869 RGD:2290271 Reactome
G MYD88 myeloid differentiation primary response 88 GBrowse link IEA 3 38,179,969 38,184,513 RGD:2290271 ENSEMBL
G NCAM1 neural cell adhesion molecule 1 GBrowse link TAS 11 112,831,969 113,149,158 RGD:2290271 Reactome
G NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase GBrowse link TAS 15 56,119,120 56,285,835 RGD:2290271 Reactome
G NUMBL numb homolog (Drosophila)-like GBrowse link IDA 19 41,171,810 41,196,556 RGD:2290271 UniProtKB
G NUP107 nucleoporin 107kDa GBrowse link TAS 12 69,080,731 69,136,473 RGD:2290271 Reactome
G NUP133 nucleoporin 133kDa GBrowse link TAS 1 229,577,044 229,644,088 RGD:2290271 Reactome
G NUP153 nucleoporin 153kDa GBrowse link TAS 6 17,615,269 17,706,818 RGD:2290271 Reactome
G NUP155 nucleoporin 155kDa GBrowse link TAS 5 37,291,941 37,371,197 RGD:2290271 Reactome
G NUP160 nucleoporin 160kDa GBrowse link TAS 11 47,799,670 47,870,057 RGD:2290271 Reactome
G NUP188 nucleoporin 188kDa GBrowse link TAS 9 131,709,977 131,769,374 RGD:2290271 Reactome
G NUP205 nucleoporin 205kDa GBrowse link TAS 7 135,242,662 135,333,501 RGD:2290271 Reactome
G NUP210 nucleoporin 210kDa GBrowse link TAS 3 13,357,737 13,461,809 RGD:2290271 Reactome
G NUP214 nucleoporin 214kDa GBrowse link TAS 9 134,000,981 134,109,091 RGD:2290271 Reactome
G NUP35 nucleoporin 35kDa GBrowse link TAS 2 183,989,083 184,026,408 RGD:2290271 Reactome
G NUP37 nucleoporin 37kDa GBrowse link TAS 12 102,467,970 102,512,361 RGD:2290271 Reactome
G NUP43 nucleoporin 43kDa GBrowse link TAS 6 150,045,457 150,067,688 RGD:2290271 Reactome
G NUP50 nucleoporin 50kDa GBrowse link TAS 22 45,559,726 45,583,892 RGD:2290271 Reactome
G NUP54 nucleoporin 54kDa GBrowse link TAS 4 77,035,817 77,069,655 RGD:2290271 Reactome
G NUP62 nucleoporin 62kDa GBrowse link TAS 19 50,410,082 50,432,988 RGD:2290271 Reactome
G NUP85 nucleoporin 85kDa GBrowse link TAS 17 73,201,597 73,231,854 RGD:2290271 Reactome
G NUP88 nucleoporin 88kDa GBrowse link TAS 17 5,289,346 5,323,059 RGD:2290271 Reactome
G NUP93 nucleoporin 93kDa GBrowse link TAS 16 56,764,017 56,878,862 RGD:2290271 Reactome
G NUP98 nucleoporin 98kDa GBrowse link TAS 11 3,696,240 3,819,022 RGD:2290271 Reactome
G NUPL1 nucleoporin like 1 GBrowse link TAS 13 25,875,666 25,916,561 RGD:2290271 Reactome
G NUPL2 nucleoporin like 2 GBrowse link TAS 7 23,221,446 23,240,630 RGD:2290271 Reactome
G OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa GBrowse link TAS 12 113,344,739 113,357,712 RGD:2290271 Reactome
G OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa GBrowse link TAS 12 113,416,274 113,449,528 RGD:2290271 Reactome
G OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa GBrowse link TAS 12 113,376,249 113,411,054 RGD:2290271 Reactome
G OASL 2'-5'-oligoadenylate synthetase-like GBrowse link TAS 12 121,458,095 121,477,045 RGD:2290271 Reactome
G PF4 platelet factor 4 GBrowse link IDA 4 74,846,542 74,847,841 RGD:2290271 UniProtKB
G PIAS1 protein inhibitor of activated STAT, 1 GBrowse link TAS 15 68,346,572 68,480,413 RGD:2290271 Reactome
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 GBrowse link TAS 19 9,945,883 9,960,365 RGD:2290271 Reactome
G PLCG1 phospholipase C, gamma 1 GBrowse link TAS 20 39,766,161 39,804,357 RGD:2290271 Reactome
G PLP2 proteolipid protein 2 (colonic epithelium-enriched) GBrowse link NAS X 49,028,184 49,031,469 RGD:2290271 UniProtKB
G PML promyelocytic leukemia GBrowse link TAS 15 74,287,014 74,340,160 RGD:2290271 Reactome
G POM121 POM121 transmembrane nucleoporin GBrowse link TAS 7 72,349,936 72,421,979 RGD:2290271 Reactome
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B GBrowse link TAS 2 44,396,000 44,461,742 RGD:2290271 Reactome
G PRKCD protein kinase C, delta GBrowse link TAS 3 53,195,223 53,226,733 RGD:2290271 Reactome
G PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 GBrowse link TAS 6 32,808,494 32,812,712 RGD:2290271 Reactome
G PTAFR platelet-activating factor receptor GBrowse link TAS 1 28,473,677 28,520,447 RGD:2290271 Reactome
G PTPN1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link TAS 20 49,126,891 49,201,088 RGD:2290271 Reactome
G PTPN11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link TAS 12 112,856,536 112,947,717 RGD:2290271 Reactome
G PTPN2 protein tyrosine phosphatase, non-receptor type 2 GBrowse link TAS 18 12,785,477 12,884,334 RGD:2290271 Reactome
G PTPN6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link TAS 12 7,055,740 7,070,479 RGD:2290271 Reactome
G RAE1 RAE1 RNA export 1 homolog (S. pombe) GBrowse link TAS 20 55,926,145 55,953,519 RGD:2290271 Reactome
G RANBP2 RAN binding protein 2 GBrowse link TAS 2 109,335,937 109,402,267 RGD:2290271 Reactome
G RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) GBrowse link IDA 11 65,421,067 65,430,443 RGD:2290271 UniProtKB
G RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) GBrowse link TAS 1 182,542,769 182,558,394 RGD:2290271 Reactome
G RPS27A ribosomal protein S27a GBrowse link TAS 2 55,459,039 55,462,989 RGD:2290271 Reactome
G RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) GBrowse link IEA 2 219,433,678 219,458,999 RGD:2290271 ENSEMBL
G SEH1L SEH1-like (S. cerevisiae) GBrowse link TAS 18 12,947,983 12,987,535 RGD:2290271 Reactome
G SH2B2 SH2B adaptor protein 2 GBrowse link IEA 7 101,928,405 101,962,178 RGD:2290271 ENSEMBL
G SOCS1 suppressor of cytokine signaling 1 GBrowse link ISS 16 11,348,274 11,350,039 RGD:2290271 UniProtKB
G SOCS1 suppressor of cytokine signaling 1 GBrowse link TAS 16 11,348,274 11,350,039 RGD:2290271 Reactome
G SOCS3 suppressor of cytokine signaling 3 GBrowse link TAS 17 76,352,859 76,356,158 RGD:2290271 Reactome
G SOCS5 suppressor of cytokine signaling 5 GBrowse link ISS 2 46,926,099 46,989,927 RGD:2290271 UniProtKB
G SP100 SP100 nuclear antigen GBrowse link TAS 2 231,280,871 231,410,317 RGD:2290271 Reactome
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link TAS 2 191,833,762 191,878,976 RGD:2290271 Reactome
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link IEA 2 191,833,762 191,878,976 RGD:2290271 ENSEMBL
G STAT2 signal transducer and activator of transcription 2, 113kDa GBrowse link TAS 12 56,735,381 56,754,037 RGD:2290271 Reactome
G STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link NAS 17 40,465,343 40,540,513 RGD:2290271 UniProtKB
G STAT4 signal transducer and activator of transcription 4 GBrowse link IEA 2 191,894,302 192,016,322 RGD:2290271 ENSEMBL
G STAT5A signal transducer and activator of transcription 5A GBrowse link IEA 17 40,439,565 40,463,961 RGD:2290271 ENSEMBL
G STAT5B signal transducer and activator of transcription 5B GBrowse link IEA 17 40,351,195 40,428,424 RGD:2290271 ENSEMBL
G STAT6 signal transducer and activator of transcription 6, interleukin-4 induced GBrowse link IEA 12 57,489,187 57,505,196 RGD:2290271 ENSEMBL
G SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) GBrowse link TAS 2 203,070,903 203,103,322 RGD:2290271 Reactome
G TNFRSF1A tumor necrosis factor receptor superfamily, member 1A GBrowse link ISS 12 6,437,923 6,451,283 RGD:2290271 UniProtKB
G TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link IDA 13 43,136,872 43,182,149 RGD:2290271 BHF-UCL
G TPR translocated promoter region, nuclear basket protein GBrowse link TAS 1 186,280,784 186,344,457 RGD:2290271 Reactome
G TYK2 tyrosine kinase 2 GBrowse link TAS 19 10,461,204 10,491,248 RGD:2290271 Reactome
G UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 GBrowse link TAS 19 18,682,614 18,688,270 RGD:2290271 Reactome
G UBA7 ubiquitin-like modifier activating enzyme 7 GBrowse link TAS 3 49,842,638 49,851,391 RGD:2290271 Reactome
G UBB ubiquitin B GBrowse link TAS 17 16,284,367 16,286,054 RGD:2290271 Reactome
G UBC ubiquitin C GBrowse link TAS 12 125,396,192 125,399,587 RGD:2290271 Reactome
G UBE2E1 ubiquitin-conjugating enzyme E2E 1 GBrowse link TAS 3 23,847,384 23,933,131 RGD:2290271 Reactome
G UBE2L6 ubiquitin-conjugating enzyme E2L 6 GBrowse link TAS 11 57,319,128 57,335,803 RGD:2290271 Reactome
G UBE2N ubiquitin-conjugating enzyme E2N GBrowse link TAS 12 93,802,088 93,836,026 RGD:2290271 Reactome
G USP18 ubiquitin specific peptidase 18 GBrowse link TAS 22 18,632,758 18,660,164 RGD:2290271 Reactome
G VCAM1 vascular cell adhesion molecule 1 GBrowse link TAS 1 101,185,196 101,204,601 RGD:2290271 Reactome
G XAF1 XIAP associated factor 1 GBrowse link TAS 17 6,659,156 6,678,966 RGD:2290271 Reactome
G ZC3H15 zinc finger CCCH-type containing 15 GBrowse link IEA 2 187,350,885 187,374,088 RGD:2290271 ENSEMBL
G ZNF675 zinc finger protein 675 GBrowse link IDA 19 23,835,708 23,870,017 RGD:2290271 UniProtKB
adiponectin-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G ACSL1 acyl-CoA synthetase long-chain family member 1 GBrowse link IEA 4 185,676,749 185,747,215 RGD:2290271 ENSEMBL
G ADIPOQ adiponectin, C1Q and collagen domain containing GBrowse link IEA 3 186,560,463 186,576,252 RGD:2290271 ENSEMBL
G CSNK2B casein kinase 2, beta polypeptide GBrowse link IDA 6 31,633,657 31,637,843 RGD:2290271 BHF-UCL
G SLC27A1 solute carrier family 27 (fatty acid transporter), member 1 GBrowse link IEA 19 17,581,300 17,616,977 RGD:2290271 ENSEMBL
chemokine (C-C motif) ligand 19 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CCR7 chemokine (C-C motif) receptor 7 GBrowse link IDA 17 38,710,021 38,721,736 RGD:2290271 GOC
chemokine (C-C motif) ligand 21 signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CCR7 chemokine (C-C motif) receptor 7 GBrowse link IDA 17 38,710,021 38,721,736 RGD:2290271 GOC
chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CCBP2 chemokine binding protein 2 GBrowse link TAS 3 42,850,964 42,908,775 RGD:2290271 GOC
G CCL2 chemokine (C-C motif) ligand 2 GBrowse link IEA 17 32,582,296 32,584,222 RGD:2290271 ENSEMBL
G CCL5 chemokine (C-C motif) ligand 5 GBrowse link TAS 17 34,198,495 34,207,377 RGD:2290271 BHF-UCL
G CCR1 chemokine (C-C motif) receptor 1 GBrowse link IDA 3 46,243,200 46,249,832 RGD:2290271 UniProtKB
G CCR2 chemokine (C-C motif) receptor 2 GBrowse link ISS 3 46,395,235 46,402,413 RGD:2290271 BHF-UCL
G CCR3 chemokine (C-C motif) receptor 3 GBrowse link TAS 3 46,283,872 46,308,197 RGD:2290271 GOC
G CCR4 chemokine (C-C motif) receptor 4 GBrowse link TAS 3 32,993,066 32,996,403 RGD:2290271 GOC
G CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) GBrowse link TAS 3 46,411,633 46,417,697 RGD:2290271 GOC
G CCR6 chemokine (C-C motif) receptor 6 GBrowse link TAS 6 167,525,295 167,552,629 RGD:2290271 GOC
G CCR8 chemokine (C-C motif) receptor 8 GBrowse link TAS 3 39,371,197 39,375,171 RGD:2290271 GOC
G CCR9 chemokine (C-C motif) receptor 9 GBrowse link TAS 3 45,927,996 45,944,667 RGD:2290271 GOC
G CCRL1 chemokine (C-C motif) receptor-like 1 GBrowse link TAS 3 132,316,094 132,321,382 RGD:2290271 GOC
G CCRL2 chemokine (C-C motif) receptor-like 2 GBrowse link TAS 3 46,448,721 46,451,014 RGD:2290271 GOC
G CMKLR1 chemokine-like receptor 1 GBrowse link TAS 12 108,681,821 108,733,094 RGD:2290271 GOC
G CX3CR1 chemokine (C-X3-C motif) receptor 1 GBrowse link TAS 3 39,304,985 39,323,226 RGD:2290271 GOC
G CXCL12 chemokine (C-X-C motif) ligand 12 GBrowse link IDA 10 44,865,605 44,880,545 RGD:2290271 BHF-UCL
G CXCR1 chemokine (C-X-C motif) receptor 1 GBrowse link TAS 2 219,027,568 219,031,716 RGD:2290271 GOC
G CXCR7 chemokine (C-X-C motif) receptor 7 GBrowse link IMP 2 237,478,380 237,490,997 RGD:2290271 BHF-UCL
G DARC Duffy blood group, chemokine receptor GBrowse link NAS 1 159,173,803 159,176,290 RGD:2290271 GOC
G GPR17 G protein-coupled receptor 17 GBrowse link TAS 2 128,403,439 128,410,213 RGD:2290271 GOC
G PTK2B protein tyrosine kinase 2 beta GBrowse link ISS 8 27,168,999 27,316,908 RGD:2290271 UniProtKB
G PTK2B protein tyrosine kinase 2 beta GBrowse link IEA 8 27,168,999 27,316,908 RGD:2290271 ENSEMBL
G TFF2 trefoil factor 2 GBrowse link IEA 21 43,766,466 43,771,208 RGD:2290271 ENSEMBL
G XCR1 chemokine (C motif) receptor 1 GBrowse link TAS 3 46,062,291 46,068,979 RGD:2290271 GOC
ciliary neurotrophic factor-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CNTF ciliary neurotrophic factor GBrowse link IDA 11 58,390,146 58,393,206 RGD:2290271 BHF-UCL
G CNTFR ciliary neurotrophic factor receptor GBrowse link IDA 9 34,551,430 34,590,138 RGD:2290271 BHF-UCL
G IL6R interleukin 6 receptor GBrowse link IMP 1 154,377,669 154,441,926 RGD:2290271 BHF-UCL
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IDA 5 55,230,923 55,290,821 RGD:2290271 BHF-UCL
G LIFR leukemia inhibitory factor receptor alpha GBrowse link IDA 5 38,475,065 38,595,507 RGD:2290271 BHF-UCL
erythropoietin-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G EPOR erythropoietin receptor GBrowse link IDA 19 11,487,881 11,495,018 RGD:2290271 GOC
G EPOR erythropoietin receptor GBrowse link TAS 19 11,487,881 11,495,018 RGD:2290271 GOC
G KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link ISS 4 55,524,095 55,606,881 RGD:2290271 UniProtKB
interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G B2M beta-2-microglobulin GBrowse link TAS 15 45,003,685 45,010,357 RGD:2290271 Reactome
G CAMK2A calcium/calmodulin-dependent protein kinase II alpha GBrowse link TAS 5 149,599,054 149,669,403 RGD:2290271 Reactome
G CAMK2B calcium/calmodulin-dependent protein kinase II beta GBrowse link TAS 7 44,256,749 44,365,230 RGD:2290271 Reactome
G CAMK2D calcium/calmodulin-dependent protein kinase II delta GBrowse link TAS 4 114,372,188 114,683,083 RGD:2290271 Reactome
G CAMK2G calcium/calmodulin-dependent protein kinase II gamma GBrowse link TAS 10 75,572,259 75,634,349 RGD:2290271 Reactome
G CD44 CD44 molecule (Indian blood group) GBrowse link TAS 11 35,160,417 35,253,949 RGD:2290271 Reactome
G CIITA class II, major histocompatibility complex, transactivator GBrowse link TAS 16 10,971,055 11,018,840 RGD:2290271 Reactome
G FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) GBrowse link TAS 1 149,754,250 149,764,074 RGD:2290271 Reactome
G FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) GBrowse link TAS 1 120,926,128 120,935,944 RGD:2290271 Reactome
G GBP1 guanylate binding protein 1, interferon-inducible GBrowse link TAS 1 89,517,987 89,531,043 RGD:2290271 Reactome
G GBP2 guanylate binding protein 2, interferon-inducible GBrowse link TAS 1 89,573,310 89,591,799 RGD:2290271 Reactome
G HCK hemopoietic cell kinase GBrowse link TAS 20 30,639,991 30,689,659 RGD:2290271 UniProtKB
G HLA-A major histocompatibility complex, class I, A GBrowse link TAS 6 29,910,247 29,913,661 RGD:2290271 Reactome
G HLA-B major histocompatibility complex, class I, B GBrowse link TAS 6 31,321,649 31,324,989 RGD:2290271 Reactome
G HLA-C major histocompatibility complex, class I, C GBrowse link TAS 6 31,236,526 31,239,913 RGD:2290271 Reactome
G HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 GBrowse link TAS 6 33,032,346 33,048,555 RGD:2290271 Reactome
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 GBrowse link TAS 6 33,043,703 33,057,473 RGD:2290271 Reactome
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 GBrowse link TAS 6 32,605,183 32,611,429 RGD:2290271 Reactome
G HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 GBrowse link TAS 6 32,709,163 32,714,664 RGD:2290271 Reactome
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 GBrowse link TAS 6 32,627,241 32,634,466 RGD:2290271 Reactome
G HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 GBrowse link TAS 6 32,723,875 32,731,330 RGD:2290271 Reactome
G HLA-DRA major histocompatibility complex, class II, DR alpha GBrowse link TAS 6 32,407,619 32,412,823 RGD:2290271 Reactome
G HLA-DRB1 major histocompatibility complex, class II, DR beta 1 GBrowse link TAS 6 32,546,546 32,557,613 RGD:2290271 Reactome
G HLA-DRB3 major histocompatibility complex, class II, DR beta 3 TAS RGD:2290271 Reactome
G HLA-DRB4 major histocompatibility complex, class II, DR beta 4 TAS RGD:2290271 Reactome
G HLA-DRB5 major histocompatibility complex, class II, DR beta 5 GBrowse link TAS 6 32,485,151 32,498,006 RGD:2290271 Reactome
G HLA-E major histocompatibility complex, class I, E GBrowse link TAS 6 30,457,183 30,461,982 RGD:2290271 Reactome
G HLA-F major histocompatibility complex, class I, F GBrowse link TAS 6 29,691,117 29,695,073 RGD:2290271 Reactome
G HLA-G major histocompatibility complex, class I, G GBrowse link TAS 6 29,794,756 29,798,899 RGD:2290271 Reactome
G ICAM1 intercellular adhesion molecule 1 GBrowse link TAS 19 10,381,517 10,397,291 RGD:2290271 Reactome
G IFI30 interferon, gamma-inducible protein 30 GBrowse link TAS 19 18,284,579 18,288,927 RGD:2290271 Reactome
G IFNG interferon, gamma GBrowse link TAS 12 68,548,550 68,553,521 RGD:2290271 Reactome
G IFNGR1 interferon gamma receptor 1 GBrowse link TAS 6 137,518,621 137,540,567 RGD:2290271 Reactome
G IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) GBrowse link TAS 21 34,775,202 34,809,828 RGD:2290271 Reactome
G IRF1 interferon regulatory factor 1 GBrowse link ISS 5 131,817,301 131,826,465 RGD:2290271 UniProtKB
G IRF1 interferon regulatory factor 1 GBrowse link TAS 5 131,817,301 131,826,465 RGD:2290271 Reactome
G IRF1 interferon regulatory factor 1 GBrowse link IEA 5 131,817,301 131,826,465 RGD:2290271 ENSEMBL
G IRF2 interferon regulatory factor 2 GBrowse link TAS 4 185,308,876 185,395,726 RGD:2290271 Reactome
G IRF3 interferon regulatory factor 3 GBrowse link TAS 19 50,162,826 50,169,132 RGD:2290271 Reactome
G IRF4 interferon regulatory factor 4 GBrowse link TAS 6 391,739 411,443 RGD:2290271 Reactome
G IRF5 interferon regulatory factor 5 GBrowse link TAS 7 128,577,994 128,590,089 RGD:2290271 Reactome
G IRF6 interferon regulatory factor 6 GBrowse link TAS 1 209,958,968 209,979,520 RGD:2290271 Reactome
G IRF7 interferon regulatory factor 7 GBrowse link TAS 11 612,555 615,999 RGD:2290271 Reactome
G IRF8 interferon regulatory factor 8 GBrowse link TAS 16 85,932,774 85,956,212 RGD:2290271 Reactome
G IRF9 interferon regulatory factor 9 GBrowse link TAS 14 24,630,422 24,635,774 RGD:2290271 Reactome
G JAK1 Janus kinase 1 GBrowse link TAS 1 65,298,906 65,432,187 RGD:2290271 Reactome
G JAK2 Janus kinase 2 GBrowse link IEA 9 4,985,245 5,128,183 RGD:2290271 ENSEMBL
G JAK2 Janus kinase 2 GBrowse link TAS 9 4,985,245 5,128,183 RGD:2290271 Reactome
G MT2A metallothionein 2A GBrowse link TAS 16 56,642,478 56,643,409 RGD:2290271 Reactome
G NCAM1 neural cell adhesion molecule 1 GBrowse link TAS 11 112,831,969 113,149,158 RGD:2290271 Reactome
G OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa GBrowse link TAS 12 113,344,739 113,357,712 RGD:2290271 Reactome
G OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa GBrowse link TAS 12 113,416,274 113,449,528 RGD:2290271 Reactome
G OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa GBrowse link TAS 12 113,376,249 113,411,054 RGD:2290271 Reactome
G OASL 2'-5'-oligoadenylate synthetase-like GBrowse link TAS 12 121,458,095 121,477,045 RGD:2290271 Reactome
G PIAS1 protein inhibitor of activated STAT, 1 GBrowse link TAS 15 68,346,572 68,480,413 RGD:2290271 Reactome
G PML promyelocytic leukemia GBrowse link TAS 15 74,287,014 74,340,160 RGD:2290271 Reactome
G PRKCD protein kinase C, delta GBrowse link TAS 3 53,195,223 53,226,733 RGD:2290271 Reactome
G PTAFR platelet-activating factor receptor GBrowse link TAS 1 28,473,677 28,520,447 RGD:2290271 Reactome
G PTPN1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link TAS 20 49,126,891 49,201,088 RGD:2290271 Reactome
G PTPN11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link TAS 12 112,856,536 112,947,717 RGD:2290271 Reactome
G PTPN2 protein tyrosine phosphatase, non-receptor type 2 GBrowse link TAS 18 12,785,477 12,884,334 RGD:2290271 Reactome
G PTPN6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link TAS 12 7,055,740 7,070,479 RGD:2290271 Reactome
G SOCS1 suppressor of cytokine signaling 1 GBrowse link TAS 16 11,348,274 11,350,039 RGD:2290271 Reactome
G SOCS3 suppressor of cytokine signaling 3 GBrowse link TAS 17 76,352,859 76,356,158 RGD:2290271 Reactome
G SP100 SP100 nuclear antigen GBrowse link IC 2 231,280,871 231,410,317 RGD:2290271 BHF-UCL
G SP100 SP100 nuclear antigen GBrowse link TAS 2 231,280,871 231,410,317 RGD:2290271 Reactome
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link IDA 2 191,833,762 191,878,976 RGD:2290271 BHF-UCL
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link TAS 2 191,833,762 191,878,976 RGD:2290271 Reactome
G SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) GBrowse link TAS 2 203,070,903 203,103,322 RGD:2290271 Reactome
G VCAM1 vascular cell adhesion molecule 1 GBrowse link TAS 1 101,185,196 101,204,601 RGD:2290271 Reactome
interleukin-1-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G EGR1 early growth response 1 GBrowse link IMP 5 137,801,181 137,805,004 RGD:2290271 BHF-UCL
G IL1R1 interleukin 1 receptor, type I GBrowse link IDA 2 102,770,402 102,796,334 RGD:2290271 BHF-UCL
G IRAK1 interleukin-1 receptor-associated kinase 1 GBrowse link IMP X 153,275,957 153,285,342 RGD:2290271 BHF-UCL
G IRAK2 interleukin-1 receptor-associated kinase 2 GBrowse link IMP 3 10,206,563 10,285,427 RGD:2290271 BHF-UCL
G IRAK3 interleukin-1 receptor-associated kinase 3 GBrowse link IMP 12 66,582,978 66,648,402 RGD:2290271 BHF-UCL
G MAPK3 mitogen-activated protein kinase 3 GBrowse link IMP 16 30,125,426 30,134,630 RGD:2290271 BHF-UCL
G PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link IDA 20 8,113,296 8,865,547 RGD:2290271 BHF-UCL
G RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 GBrowse link IMP 11 64,126,625 64,139,687 RGD:2290271 BHF-UCL
G RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 GBrowse link IMP 14 91,337,159 91,526,993 RGD:2290271 BHF-UCL
G TNIP2 TNFAIP3 interacting protein 2 GBrowse link ISS 4 2,743,387 2,758,103 RGD:2290271 UniProtKB
G TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase GBrowse link IEA 11 36,505,317 36,531,863 RGD:2290271 ENSEMBL
G TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase GBrowse link IEA 11 36,505,317 36,531,863 RGD:2290271 ENSEMBL
interleukin-12-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL12RB1 interleukin 12 receptor, beta 1 GBrowse link IDA 19 18,170,371 18,197,697 RGD:2290271 GOC
G JAK2 Janus kinase 2 GBrowse link IDA 9 4,985,245 5,128,183 RGD:2290271 BHF-UCL
G PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link IDA 20 8,113,296 8,865,547 RGD:2290271 BHF-UCL
interleukin-15-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link IDA 20 8,113,296 8,865,547 RGD:2290271 BHF-UCL
interleukin-2-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL2RB interleukin 2 receptor, beta GBrowse link TAS 22 37,521,878 37,545,962 RGD:2290271 GOC
G IL2RB interleukin 2 receptor, beta GBrowse link IDA 22 37,521,878 37,545,962 RGD:2290271 GOC
G IL2RG interleukin 2 receptor, gamma GBrowse link TAS X 70,327,254 70,331,481 RGD:2290271 GOC
interleukin-21-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL21R interleukin 21 receptor GBrowse link NAS 16 27,413,483 27,463,363 RGD:2290271 GOC
interleukin-23-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL12RB1 interleukin 12 receptor, beta 1 GBrowse link IDA 19 18,170,371 18,197,697 RGD:2290271 GOC
G IL23R interleukin 23 receptor GBrowse link IDA 1 67,632,169 67,725,662 RGD:2290271 GOC
interleukin-27-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IMP 5 55,230,923 55,290,821 RGD:2290271 BHF-UCL
interleukin-3-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GBrowse link TAS 22 37,309,675 37,336,481 RGD:2290271 GOC
G IL3RA interleukin 3 receptor, alpha (low affinity) GBrowse link TAS X
Y		 1,455,509
1,405,509		 1,501,582
1,451,582		 RGD:2290271 GOC
interleukin-4-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL2RG interleukin 2 receptor, gamma GBrowse link TAS X 70,327,254 70,331,481 RGD:2290271 GOC
G IL4R interleukin 4 receptor GBrowse link TAS 16 27,325,230 27,376,099 RGD:2290271 GOC
G JAK3 Janus kinase 3 GBrowse link IDA 19 17,935,591 17,958,841 RGD:2290271 BHF-UCL
interleukin-5-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) GBrowse link TAS 22 37,309,675 37,336,481 RGD:2290271 GOC
G IL5RA interleukin 5 receptor, alpha GBrowse link TAS 3 3,108,008 3,152,058 RGD:2290271 GOC
interleukin-6-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CTR9 Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) GBrowse link ISS 11 10,772,811 10,801,290 RGD:2290271 UniProtKB
G FER fer (fps/fes related) tyrosine kinase GBrowse link IMP 5 108,083,523 108,523,373 RGD:2290271 UniProtKB
G GAB1 GRB2-associated binding protein 1 GBrowse link IEA 4 144,257,983 144,395,718 RGD:2290271 ENSEMBL
G IL6 interleukin 6 (interferon, beta 2) GBrowse link IDA 7 22,766,766 22,771,621 RGD:2290271 BHF-UCL
G IL6 interleukin 6 (interferon, beta 2) GBrowse link IEA 7 22,766,766 22,771,621 RGD:2290271 ENSEMBL
G IL6R interleukin 6 receptor GBrowse link IMP 1 154,377,669 154,441,926 RGD:2290271 BHF-UCL
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IGI 5 55,230,923 55,290,821 RGD:2290271 GOC
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IDA 5 55,230,923 55,290,821 RGD:2290271 GOC
G STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link IDA 17 40,465,343 40,540,513 RGD:2290271 BHF-UCL
G STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) GBrowse link IDA 17 40,465,343 40,540,513 RGD:2290271 BHF-UCL
G ZCCHC11 zinc finger, CCHC domain containing 11 GBrowse link IEA 1 52,888,947 53,018,762 RGD:2290271 ENSEMBL
interleukin-7-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL2RG interleukin 2 receptor, gamma GBrowse link TAS X 70,327,254 70,331,481 RGD:2290271 GOC
G IL7R interleukin 7 receptor GBrowse link TAS 5 35,856,977 35,879,705 RGD:2290271 GOC
interleukin-8-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CXCR1 chemokine (C-X-C motif) receptor 1 GBrowse link IDA 2 219,027,568 219,031,716 RGD:2290271 GOC
G CXCR2 chemokine (C-X-C motif) receptor 2 GBrowse link IDA 2 218,990,013 219,001,976 RGD:2290271 GOC
interleukin-9-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL9R interleukin 9 receptor GBrowse link TAS X
Y		 155,227,246
59,330,252		 155,240,482
59,343,488		 RGD:2290271 GOC
Kit signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G FER fer (fps/fes related) tyrosine kinase GBrowse link ISS 5 108,083,523 108,523,373 RGD:2290271 UniProtKB
G KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog GBrowse link IDA 4 55,524,095 55,606,881 RGD:2290271 UniProtKB
leptin-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G LEP leptin GBrowse link IEA 7 127,881,331 127,897,682 RGD:2290271 ENSEMBL
G MT3 metallothionein 3 GBrowse link ISS 16 56,623,267 56,625,000 RGD:2290271 UniProtKB
macrophage colony-stimulating factor signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CSF1R colony stimulating factor 1 receptor GBrowse link TAS 5 149,432,854 149,492,935 RGD:2290271 GOC
G CSF1R colony stimulating factor 1 receptor GBrowse link IMP 5 149,432,854 149,492,935 RGD:2290271 GOC
G CSF1R colony stimulating factor 1 receptor GBrowse link IMP 5 149,432,854 149,492,935 RGD:2290271 GOC
G MST1R macrophage stimulating 1 receptor (c-met-related tyrosine kinase) GBrowse link TAS 3 49,924,435 49,941,306 RGD:2290271 GOC
macrophage migration inhibitory factor signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CD74 CD74 molecule, major histocompatibility complex, class II invariant chain GBrowse link IEA 5 149,781,200 149,792,499 RGD:2290271 ENSEMBL
negative regulation of appetite by leptin-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G BBS2 Bardet-Biedl syndrome 2 GBrowse link ISS 16 56,518,259 56,554,008 RGD:2290271 BHF-UCL
G BBS2 Bardet-Biedl syndrome 2 GBrowse link IEA 16 56,518,259 56,554,008 RGD:2290271 ENSEMBL
G BBS4 Bardet-Biedl syndrome 4 GBrowse link ISS 15 72,978,520 73,030,817 RGD:2290271 BHF-UCL
G BBS4 Bardet-Biedl syndrome 4 GBrowse link IEA 15 72,978,520 73,030,817 RGD:2290271 ENSEMBL
G MKKS McKusick-Kaufman syndrome GBrowse link ISS 20 10,385,428 10,414,887 RGD:2290271 BHF-UCL
negative regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CCL5 chemokine (C-C motif) ligand 5 GBrowse link IDA 17 34,198,495 34,207,377 RGD:2290271 GOC
G ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) GBrowse link IMP 3 78,646,388 79,817,059 RGD:2290271 BHF-UCL
G SLIT2 slit homolog 2 (Drosophila) GBrowse link IMP 4 20,255,235 20,620,788 RGD:2290271 BHF-UCL
G SLIT3 slit homolog 3 (Drosophila) GBrowse link IMP 5 168,093,071 168,728,133 RGD:2290271 BHF-UCL
negative regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CAV1 caveolin 1, caveolae protein, 22kDa GBrowse link IEA 7 116,164,839 116,201,239 RGD:2290271 ENSEMBL
G ECM1 extracellular matrix protein 1 GBrowse link IEA 1 150,480,487 150,486,265 RGD:2290271 ENSEMBL
G IL1RN interleukin 1 receptor antagonist GBrowse link IDA 2 113,875,470 113,891,593 RGD:2290271 GOC
G IL36RN interleukin 36 receptor antagonist GBrowse link TAS 2 113,816,215 113,822,321 RGD:2290271 GOC
G IRAK3 interleukin-1 receptor-associated kinase 3 GBrowse link IC 12 66,582,978 66,648,402 RGD:2290271 BHF-UCL
G PALM3 paralemmin 3 GBrowse link IDA 19 14,164,179 14,169,971 RGD:2290271 UniProtKB
G PTPRC protein tyrosine phosphatase, receptor type, C GBrowse link ISS 1 198,608,098 198,726,605 RGD:2290271 UniProtKB
G PTPRC protein tyrosine phosphatase, receptor type, C GBrowse link IEA 1 198,608,098 198,726,605 RGD:2290271 ENSEMBL
G PXDN peroxidasin homolog (Drosophila) GBrowse link NAS 2 1,635,659 1,748,291 RGD:2290271 GOC
G SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain GBrowse link ISS 11 405,716 417,397 RGD:2290271 HGNC
negative regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link IDA 16 4,475,806 4,506,776 RGD:2290271 UniProtKB
G NR1H2 nuclear receptor subfamily 1, group H, member 2 GBrowse link NAS 19 50,879,680 50,886,285 RGD:2290271 BHF-UCL
G NR1H3 nuclear receptor subfamily 1, group H, member 3 GBrowse link NAS 11 47,269,851 47,290,584 RGD:2290271 BHF-UCL
G PPARG peroxisome proliferator-activated receptor gamma GBrowse link IMP 3 12,329,349 12,475,855 RGD:2290271 BHF-UCL
negative regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL1RN interleukin 1 receptor antagonist GBrowse link IDA 2 113,875,470 113,891,593 RGD:2290271 BHF-UCL
G IL1RN interleukin 1 receptor antagonist GBrowse link IDA 2 113,875,470 113,891,593 RGD:2290271 BHF-UCL
G ZNF675 zinc finger protein 675 GBrowse link IDA 19 23,835,708 23,870,017 RGD:2290271 BHF-UCL
negative regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IDA 5 55,230,923 55,290,821 RGD:2290271 BHF-UCL
negative regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G ADIPOQ adiponectin, C1Q and collagen domain containing GBrowse link IDA 3 186,560,463 186,576,252 RGD:2290271 BHF-UCL
G APOA1 apolipoprotein A-I GBrowse link IDA 11 116,706,469 116,708,338 RGD:2290271 BHF-UCL
G F2RL1 coagulation factor II (thrombin) receptor-like 1 GBrowse link IDA 5 76,114,833 76,131,140 RGD:2290271 UniProtKB
G GAS6 growth arrest-specific 6 GBrowse link IDA 13 114,523,522 114,567,046 RGD:2290271 UniProtKB
G GSTP1 glutathione S-transferase pi 1 GBrowse link IC 11 67,351,066 67,354,124 RGD:2290271 BHF-UCL
G ZNF675 zinc finger protein 675 GBrowse link IDA 19 23,835,708 23,870,017 RGD:2290271 BHF-UCL
negative regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CACTIN cactin, spliceosome C complex subunit GBrowse link IMP 19 3,610,626 3,626,813 RGD:2290271 UniProtKB
G NLRC5 NLR family, CARD domain containing 5 GBrowse link IDA 16 57,050,986 57,117,436 RGD:2290271 UniProtKB
oncostatin-M-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) GBrowse link IDA 5 55,230,923 55,290,821 RGD:2290271 GOC
G LIFR leukemia inhibitory factor receptor alpha GBrowse link IDA 5 38,475,065 38,595,507 RGD:2290271 GOC
G OSMR oncostatin M receptor GBrowse link IDA 5 38,845,960 38,935,743 RGD:2290271 GOC
positive regulation of chemokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G EDN1 endothelin 1 GBrowse link IC 6 12,290,529 12,297,427 RGD:2290271 BHF-UCL
G HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link IC 14 62,162,119 62,214,977 RGD:2290271 BHF-UCL
positive regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 GBrowse link IC 6 32,135,983 32,145,888 RGD:2290271 BHF-UCL
G AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 GBrowse link IC 9 139,567,595 139,581,911 RGD:2290271 BHF-UCL
G AXL AXL receptor tyrosine kinase GBrowse link IDA 19 41,725,108 41,767,671 RGD:2290271 UniProtKB
G CD74 CD74 molecule, major histocompatibility complex, class II invariant chain GBrowse link IMP 5 149,781,200 149,792,499 RGD:2290271 BHF-UCL
G GAS6 growth arrest-specific 6 GBrowse link IMP 13 114,523,522 114,567,046 RGD:2290271 UniProtKB
G PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) GBrowse link IEA 17 2,496,923 2,588,909 RGD:2290271 ENSEMBL
G RIPK2 receptor-interacting serine-threonine kinase 2 GBrowse link IEA 8 90,769,975 90,803,292 RGD:2290271 ENSEMBL
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator GBrowse link IMP 18 59,992,520 60,054,943 RGD:2290271 BHF-UCL
G TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link IDA 13 43,136,872 43,182,149 RGD:2290271 BHF-UCL
positive regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G HPX hemopexin GBrowse link IEA 11 6,452,268 6,462,254 RGD:2290271 ENSEMBL
G MED1 mediator complex subunit 1 GBrowse link IEA 17 37,560,538 37,607,527 RGD:2290271 ENSEMBL
G NLRC5 NLR family, CARD domain containing 5 GBrowse link IDA 16 57,050,986 57,117,436 RGD:2290271 UniProtKB
G NLRC5 NLR family, CARD domain containing 5 GBrowse link IMP 16 57,050,986 57,117,436 RGD:2290271 BHF-UCL
G TXK TXK tyrosine kinase GBrowse link IDA 4 48,068,410 48,136,273 RGD:2290271 UniProtKB
positive regulation of interleukin-6-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G GFI1 growth factor independent 1 transcription repressor GBrowse link IDA 1 92,940,318 92,952,433 RGD:2290271 UniProtKB
positive regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G FADD Fas (TNFRSF6)-associated via death domain GBrowse link IMP 11 70,049,269 70,053,508 RGD:2290271 UniProtKB
G IRF7 interferon regulatory factor 7 GBrowse link IEA 11 612,555 615,999 RGD:2290271 ENSEMBL
G MAVS mitochondrial antiviral signaling protein GBrowse link IDA 20 3,827,446 3,856,770 RGD:2290271 BHF-UCL
G MAVS mitochondrial antiviral signaling protein GBrowse link IDA 20 3,827,446 3,856,770 RGD:2290271 UniProtKB
G NLRC5 NLR family, CARD domain containing 5 GBrowse link IDA 16 57,050,986 57,117,436 RGD:2290271 UniProtKB
G WNT5A wingless-type MMTV integration site family, member 5A GBrowse link IDA 3 55,499,743 55,521,670 RGD:2290271 BHF-UCL
G ZBP1 Z-DNA binding protein 1 GBrowse link IEA 20 56,178,902 56,195,632 RGD:2290271 ENSEMBL
prolactin signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G PRLR prolactin receptor GBrowse link NAS 5 35,048,861 35,230,823 RGD:2290271 GOC
G PRLR prolactin receptor GBrowse link TAS 5 35,048,861 35,230,823 RGD:2290271 GOC
regulation of cytokine-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CD24 CD24 molecule ISS RGD:2290271 UniProtKB
G IRAK1 interleukin-1 receptor-associated kinase 1 GBrowse link IMP X 153,275,957 153,285,342 RGD:2290271 BHF-UCL
G IRAK2 interleukin-1 receptor-associated kinase 2 GBrowse link IMP 3 10,206,563 10,285,427 RGD:2290271 BHF-UCL
regulation of interferon-gamma-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CDC37 cell division cycle 37 GBrowse link IMP 19 10,501,809 10,514,271 RGD:2290271 MGI
G HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 GBrowse link IMP 6 44,214,849 44,221,614 RGD:2290271 MGI
G IFNG interferon, gamma GBrowse link TAS 12 68,548,550 68,553,521 RGD:2290271 Reactome
G IFNGR1 interferon gamma receptor 1 GBrowse link TAS 6 137,518,621 137,540,567 RGD:2290271 Reactome
G IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1) GBrowse link TAS 21 34,775,202 34,809,828 RGD:2290271 Reactome
G JAK1 Janus kinase 1 GBrowse link TAS 1 65,298,906 65,432,187 RGD:2290271 Reactome
G JAK2 Janus kinase 2 GBrowse link TAS 9 4,985,245 5,128,183 RGD:2290271 Reactome
G PIAS1 protein inhibitor of activated STAT, 1 GBrowse link TAS 15 68,346,572 68,480,413 RGD:2290271 Reactome
G PTPN1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link TAS 20 49,126,891 49,201,088 RGD:2290271 Reactome
G PTPN11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link TAS 12 112,856,536 112,947,717 RGD:2290271 Reactome
G PTPN2 protein tyrosine phosphatase, non-receptor type 2 GBrowse link TAS 18 12,785,477 12,884,334 RGD:2290271 Reactome
G PTPN6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link TAS 12 7,055,740 7,070,479 RGD:2290271 Reactome
G SOCS1 suppressor of cytokine signaling 1 GBrowse link TAS 16 11,348,274 11,350,039 RGD:2290271 Reactome
G SOCS3 suppressor of cytokine signaling 3 GBrowse link TAS 17 76,352,859 76,356,158 RGD:2290271 Reactome
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link TAS 2 191,833,762 191,878,976 RGD:2290271 Reactome
G SUMO1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) GBrowse link TAS 2 203,070,903 203,103,322 RGD:2290271 Reactome
regulation of interleukin-1-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G VRK2 vaccinia related kinase 2 GBrowse link IMP 2 58,273,777 58,387,055 RGD:2290271 UniProtKB
regulation of tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G HIPK1 homeodomain interacting protein kinase 1 GBrowse link IDA 1 114,471,996 114,520,491 RGD:2290271 UniProtKB
G PYCARD PYD and CARD domain containing GBrowse link IMP 16 31,212,807 31,214,097 RGD:2290271 UniProtKB
G SHARPIN SHANK-associated RH domain interactor GBrowse link IDA 8 145,153,536 145,159,140 RGD:2290271 UniProtKB
G SPHK1 sphingosine kinase 1 GBrowse link IDA 17 74,380,690 74,383,941 RGD:2290271 UniProtKB
regulation of type I interferon-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G CDC37 cell division cycle 37 GBrowse link IMP 19 10,501,809 10,514,271 RGD:2290271 MGI
G HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 GBrowse link IMP 6 44,214,849 44,221,614 RGD:2290271 MGI
G IFNA1 interferon, alpha 1 GBrowse link TAS 9 21,440,453 21,441,315 RGD:2290271 Reactome
G IFNA10 interferon, alpha 10 GBrowse link TAS 9 21,206,180 21,207,142 RGD:2290271 Reactome
G IFNA13 interferon, alpha 13 GBrowse link TAS 9 21,367,371 21,368,075 RGD:2290271 Reactome
G IFNA14 interferon, alpha 14 GBrowse link TAS 9 21,239,201 21,239,978 RGD:2290271 Reactome
G IFNA16 interferon, alpha 16 GBrowse link TAS 9 21,216,372 21,217,310 RGD:2290271 Reactome
G IFNA17 interferon, alpha 17 GBrowse link TAS 9 21,227,242 21,228,221 RGD:2290271 Reactome
G IFNA2 interferon, alpha 2 GBrowse link TAS 9 21,384,254 21,385,396 RGD:2290271 Reactome
G IFNA21 interferon, alpha 21 GBrowse link TAS 9 21,165,636 21,166,659 RGD:2290271 Reactome
G IFNA4 interferon, alpha 4 GBrowse link TAS 9 21,186,617 21,187,598 RGD:2290271 Reactome
G IFNA5 interferon, alpha 5 GBrowse link TAS 9 21,304,613 21,305,312 RGD:2290271 Reactome
G IFNA6 interferon, alpha 6 GBrowse link TAS 9 21,350,317 21,350,886 RGD:2290271 Reactome
G IFNA7 interferon, alpha 7 GBrowse link TAS 9 21,201,468 21,202,204 RGD:2290271 Reactome
G IFNA8 interferon, alpha 8 GBrowse link TAS 9 21,409,146 21,410,184 RGD:2290271 Reactome
G IFNAR1 interferon (alpha, beta and omega) receptor 1 GBrowse link TAS 21 34,697,214 34,732,129 RGD:2290271 Reactome
G IFNAR2 interferon (alpha, beta and omega) receptor 2 GBrowse link TAS 21 34,602,231 34,636,827 RGD:2290271 Reactome
G IFNB1 interferon, beta 1, fibroblast GBrowse link TAS 9 21,077,104 21,077,943 RGD:2290271 Reactome
G JAK1 Janus kinase 1 GBrowse link TAS 1 65,298,906 65,432,187 RGD:2290271 Reactome
G PTPN1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link TAS 20 49,126,891 49,201,088 RGD:2290271 Reactome
G PTPN11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link TAS 12 112,856,536 112,947,717 RGD:2290271 Reactome
G PTPN6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link TAS 12 7,055,740 7,070,479 RGD:2290271 Reactome
G SOCS1 suppressor of cytokine signaling 1 GBrowse link TAS 16 11,348,274 11,350,039 RGD:2290271 Reactome
G SOCS3 suppressor of cytokine signaling 3 GBrowse link TAS 17 76,352,859 76,356,158 RGD:2290271 Reactome
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link TAS 2 191,833,762 191,878,976 RGD:2290271 Reactome
G STAT2 signal transducer and activator of transcription 2, 113kDa GBrowse link TAS 12 56,735,381 56,754,037 RGD:2290271 Reactome
G TYK2 tyrosine kinase 2 GBrowse link TAS 19 10,461,204 10,491,248 RGD:2290271 Reactome
G USP18 ubiquitin specific peptidase 18 GBrowse link TAS 22 18,632,758 18,660,164 RGD:2290271 Reactome
TNFSF11-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator GBrowse link IMP 18 59,992,520 60,054,943 RGD:2290271 BHF-UCL
G TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link IDA 13 43,136,872 43,182,149 RGD:2290271 BHF-UCL
tumor necrosis factor-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G AIM2 absent in melanoma 2 GBrowse link IDA 1 159,032,275 159,046,647 RGD:2290271 UniProtKB
G CDIP1 cell death-inducing p53 target 1 GBrowse link IGI 16 4,560,676 4,588,816 RGD:2290271 MGI
G COMMD7 COMM domain containing 7 GBrowse link IDA 20 31,290,493 31,331,814 RGD:2290271 UniProtKB
G EDA2R ectodysplasin A2 receptor GBrowse link NAS X 65,815,479 65,859,140 RGD:2290271 GOC
G JAK2 Janus kinase 2 GBrowse link IDA 9 4,985,245 5,128,183 RGD:2290271 BHF-UCL
G KRT18 keratin 18 GBrowse link IEA 12 53,342,655 53,346,685 RGD:2290271 ENSEMBL
G PTK2B protein tyrosine kinase 2 beta GBrowse link IMP 8 27,168,999 27,316,908 RGD:2290271 UniProtKB
G PYCARD PYD and CARD domain containing GBrowse link IDA 16 31,212,807 31,214,097 RGD:2290271 HGNC
G PYDC1 PYD (pyrin domain) containing 1 GBrowse link IDA 16 31,227,283 31,228,398 RGD:2290271 HGNC
G RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 GBrowse link IC 6 3,077,058 3,115,421 RGD:2290271 BHF-UCL
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link IDA 2 191,833,762 191,878,976 RGD:2290271 UniProtKB
G TNF tumor necrosis factor GBrowse link IMP 6 31,543,344 31,546,113 RGD:2290271 BHF-UCL
G TNF tumor necrosis factor GBrowse link IEA 6 31,543,344 31,546,113 RGD:2290271 ENSEMBL
G TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator GBrowse link ISS 18 59,992,520 60,054,943 RGD:2290271 BHF-UCL
G TNFRSF14 tumor necrosis factor receptor superfamily, member 14 GBrowse link TAS 1 2,487,805 2,495,268 RGD:2290271 GOC
G TNFRSF17 tumor necrosis factor receptor superfamily, member 17 GBrowse link RCA 16 12,058,964 12,061,925 RGD:2290271 GOC
G TNFRSF18 tumor necrosis factor receptor superfamily, member 18 GBrowse link TAS 1 1,138,888 1,142,089 RGD:2290271 GOC
G TNFRSF19 tumor necrosis factor receptor superfamily, member 19 GBrowse link NAS 13 24,144,509 24,250,244 RGD:2290271 GOC
G TNFRSF25 tumor necrosis factor receptor superfamily, member 25 GBrowse link TAS 1 6,521,211 6,526,255 RGD:2290271 GOC
G TNFRSF8 tumor necrosis factor receptor superfamily, member 8 GBrowse link RCA 1 12,123,434 12,204,264 RGD:2290271 GOC
G TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 GBrowse link ISS 13 43,136,872 43,182,149 RGD:2290271 BHF-UCL
G TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 GBrowse link ISS 1 173,010,360 173,020,103 RGD:2290271 UniProtKB
G TRADD TNFRSF1A-associated via death domain GBrowse link TAS 16 67,188,088 67,193,812 RGD:2290271 BHF-UCL
G TRAF2 TNF receptor-associated factor 2 GBrowse link IEA 9 139,780,965 139,821,067 RGD:2290271 InterPro
G TRAF2 TNF receptor-associated factor 2 GBrowse link IDA 9 139,780,965 139,821,067 RGD:2290271 UniProtKB
G TRAF3 TNF receptor-associated factor 3 GBrowse link IEA 14 103,243,816 103,377,837 RGD:2290271 InterPro
G TRAF3 TNF receptor-associated factor 3 GBrowse link IMP 14 103,243,816 103,377,837 RGD:2290271 UniProtKB
G TXNDC17 thioredoxin domain containing 17 GBrowse link IMP 17 6,544,222 6,547,861 RGD:2290271 UniProtKB
type I interferon-mediated signaling pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G ADAR adenosine deaminase, RNA-specific GBrowse link TAS 1 154,554,533 154,600,456 RGD:2290271 Reactome
G EGR1 early growth response 1 GBrowse link TAS 5 137,801,181 137,805,004 RGD:2290271 Reactome
G GBP2 guanylate binding protein 2, interferon-inducible GBrowse link TAS 1 89,573,310 89,591,799 RGD:2290271 Reactome
G HLA-A major histocompatibility complex, class I, A GBrowse link TAS 6 29,910,247 29,913,661 RGD:2290271 Reactome
G HLA-B major histocompatibility complex, class I, B GBrowse link TAS 6 31,321,649 31,324,989 RGD:2290271 Reactome
G HLA-C major histocompatibility complex, class I, C GBrowse link TAS 6 31,236,526 31,239,913 RGD:2290271 Reactome
G HLA-E major histocompatibility complex, class I, E GBrowse link TAS 6 30,457,183 30,461,982 RGD:2290271 Reactome
G HLA-F major histocompatibility complex, class I, F GBrowse link TAS 6 29,691,117 29,695,073 RGD:2290271 Reactome
G HLA-G major histocompatibility complex, class I, G GBrowse link TAS 6 29,794,756 29,798,899 RGD:2290271 Reactome
G IFI27 interferon, alpha-inducible protein 27 GBrowse link TAS 14 94,577,079 94,583,033 RGD:2290271 Reactome
G IFI35 interferon-induced protein 35 GBrowse link TAS 17 41,158,742 41,166,476 RGD:2290271 Reactome
G IFI6 interferon, alpha-inducible protein 6 GBrowse link TAS 1 27,992,572 27,998,724 RGD:2290271 Reactome
G IFIT1 interferon-induced protein with tetratricopeptide repeats 1 GBrowse link TAS 10 91,152,303 91,166,244 RGD:2290271 Reactome
G IFIT2 interferon-induced protein with tetratricopeptide repeats 2 GBrowse link TAS 10 91,061,706 91,069,033 RGD:2290271 Reactome
G IFIT3 interferon-induced protein with tetratricopeptide repeats 3 GBrowse link TAS 10 91,087,602 91,100,725 RGD:2290271 Reactome
G IFITM1 interferon induced transmembrane protein 1 GBrowse link TAS 11 313,991 315,272 RGD:2290271 Reactome
G IFITM2 interferon induced transmembrane protein 2 GBrowse link TAS 11 308,107 309,410 RGD:2290271 Reactome
G IFITM3 interferon induced transmembrane protein 3 GBrowse link TAS 11 319,673 320,914 RGD:2290271 Reactome
G IFNA1 interferon, alpha 1 GBrowse link TAS 9 21,440,453 21,441,315 RGD:2290271 Reactome
G IFNA10 interferon, alpha 10 GBrowse link TAS 9 21,206,180 21,207,142 RGD:2290271 Reactome
G IFNA13 interferon, alpha 13 GBrowse link TAS 9 21,367,371 21,368,075 RGD:2290271 Reactome
G IFNA14 interferon, alpha 14 GBrowse link TAS 9 21,239,201 21,239,978 RGD:2290271 Reactome
G IFNA16 interferon, alpha 16 GBrowse link TAS 9 21,216,372 21,217,310 RGD:2290271 Reactome
G IFNA17 interferon, alpha 17 GBrowse link TAS 9 21,227,242 21,228,221 RGD:2290271 Reactome
G IFNA2 interferon, alpha 2 GBrowse link TAS 9 21,384,254 21,385,396 RGD:2290271 Reactome
G IFNA21 interferon, alpha 21 GBrowse link TAS 9 21,165,636 21,166,659 RGD:2290271 Reactome
G IFNA4 interferon, alpha 4 GBrowse link TAS 9 21,186,617 21,187,598 RGD:2290271 Reactome
G IFNA5 interferon, alpha 5 GBrowse link TAS 9 21,304,613 21,305,312 RGD:2290271 Reactome
G IFNA6 interferon, alpha 6 GBrowse link TAS 9 21,350,317 21,350,886 RGD:2290271 Reactome
G IFNA7 interferon, alpha 7 GBrowse link TAS 9 21,201,468 21,202,204 RGD:2290271 Reactome
G IFNA8 interferon, alpha 8 GBrowse link TAS 9 21,409,146 21,410,184 RGD:2290271 Reactome
G IFNAR1 interferon (alpha, beta and omega) receptor 1 GBrowse link TAS 21 34,697,214 34,732,129 RGD:2290271 Reactome
G IFNAR2 interferon (alpha, beta and omega) receptor 2 GBrowse link TAS 21 34,602,231 34,636,827 RGD:2290271 Reactome
G IFNB1 interferon, beta 1, fibroblast GBrowse link TAS 9 21,077,104 21,077,943 RGD:2290271 Reactome
G IP6K2 inositol hexakisphosphate kinase 2 GBrowse link TAS 3 48,725,436 48,754,711 RGD:2290271 Reactome
G IRF1 interferon regulatory factor 1 GBrowse link TAS 5 131,817,301 131,826,465 RGD:2290271 Reactome
G IRF2 interferon regulatory factor 2 GBrowse link TAS 4 185,308,876 185,395,726 RGD:2290271 Reactome
G IRF3 interferon regulatory factor 3 GBrowse link TAS 19 50,162,826 50,169,132 RGD:2290271 Reactome
G IRF4 interferon regulatory factor 4 GBrowse link TAS 6 391,739 411,443 RGD:2290271 Reactome
G IRF5 interferon regulatory factor 5 GBrowse link TAS 7 128,577,994 128,590,089 RGD:2290271 Reactome
G IRF6 interferon regulatory factor 6 GBrowse link TAS 1 209,958,968 209,979,520 RGD:2290271 Reactome
G IRF7 interferon regulatory factor 7 GBrowse link TAS 11 612,555 615,999 RGD:2290271 Reactome
G IRF8 interferon regulatory factor 8 GBrowse link TAS 16 85,932,774 85,956,212 RGD:2290271 Reactome
G IRF9 interferon regulatory factor 9 GBrowse link TAS 14 24,630,422 24,635,774 RGD:2290271 Reactome
G ISG15 ISG15 ubiquitin-like modifier GBrowse link TAS 1 948,847 949,920 RGD:2290271 Reactome
G ISG20 interferon stimulated exonuclease gene 20kDa GBrowse link TAS 15 89,182,039 89,198,879 RGD:2290271 Reactome
G JAK1 Janus kinase 1 GBrowse link TAS 1 65,298,906 65,432,187 RGD:2290271 Reactome
G MX1 myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) GBrowse link TAS 21 42,792,520 42,831,141 RGD:2290271 Reactome
G MX2 myxovirus (influenza virus) resistance 2 (mouse) GBrowse link TAS 21 42,733,950 42,780,869 RGD:2290271 Reactome
G OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa GBrowse link TAS 12 113,344,739 113,357,712 RGD:2290271 Reactome
G OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa GBrowse link TAS 12 113,416,274 113,449,528 RGD:2290271 Reactome
G OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa GBrowse link TAS 12 113,376,249 113,411,054 RGD:2290271 Reactome
G OASL 2'-5'-oligoadenylate synthetase-like GBrowse link TAS 12 121,458,095 121,477,045 RGD:2290271 Reactome
G PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 GBrowse link TAS 6 32,808,494 32,812,712 RGD:2290271 Reactome
G PTPN1 protein tyrosine phosphatase, non-receptor type 1 GBrowse link TAS 20 49,126,891 49,201,088 RGD:2290271 Reactome
G PTPN11 protein tyrosine phosphatase, non-receptor type 11 GBrowse link TAS 12 112,856,536 112,947,717 RGD:2290271 Reactome
G PTPN6 protein tyrosine phosphatase, non-receptor type 6 GBrowse link TAS 12 7,055,740 7,070,479 RGD:2290271 Reactome
G RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) GBrowse link TAS 1 182,542,769 182,558,394 RGD:2290271 Reactome
G SOCS1 suppressor of cytokine signaling 1 GBrowse link TAS 16 11,348,274 11,350,039 RGD:2290271 Reactome
G SOCS3 suppressor of cytokine signaling 3 GBrowse link TAS 17 76,352,859 76,356,158 RGD:2290271 Reactome
G SP100 SP100 nuclear antigen GBrowse link IC 2 231,280,871 231,410,317 RGD:2290271 BHF-UCL
G STAT1 signal transducer and activator of transcription 1, 91kDa GBrowse link TAS 2 191,833,762 191,878,976 RGD:2290271 Reactome
G STAT2 signal transducer and activator of transcription 2, 113kDa GBrowse link TAS 12 56,735,381 56,754,037 RGD:2290271 Reactome
G TYK2 tyrosine kinase 2 GBrowse link TAS 19 10,461,204 10,491,248 RGD:2290271 Reactome
G USP18 ubiquitin specific peptidase 18 GBrowse link TAS 22 18,632,758 18,660,164 RGD:2290271 Reactome
G XAF1 XIAP associated factor 1 GBrowse link TAS 17 6,659,156 6,678,966 RGD:2290271 Reactome
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 117121
    single-organism process 69555
      single organism signaling 15984
        signal transduction 13710
          cell surface receptor signaling pathway 6011
            cytokine-mediated signaling pathway 600
              Kit signaling pathway + 2
              adiponectin-mediated signaling pathway 4
              chemokine-mediated signaling pathway + 32
              ciliary neurotrophic factor-mediated signaling pathway 5
              erythropoietin-mediated signaling pathway 3
              granulocyte colony-stimulating factor signaling pathway 0
              granulocyte-macrophage colony-stimulating factor signaling pathway 0
              interferon-gamma-mediated signaling pathway + 95
              interleukin-1-mediated signaling pathway + 16
              interleukin-11-mediated signaling pathway 0
              interleukin-12-mediated signaling pathway 3
              interleukin-13-mediated signaling pathway 0
              interleukin-15-mediated signaling pathway 1
              interleukin-17-mediated signaling pathway 0
              interleukin-17A-mediated signaling pathway 0
              interleukin-18-mediated signaling pathway + 0
              interleukin-2-mediated signaling pathway 3
              interleukin-21-mediated signaling pathway 1
              interleukin-23-mediated signaling pathway 2
              interleukin-27-mediated signaling pathway + 1
              interleukin-3-mediated signaling pathway 2
              interleukin-32-mediated signaling pathway 0
              interleukin-33-mediated signaling pathway 0
              interleukin-34-mediated signaling pathway 0
              interleukin-35-mediated signaling pathway + 0
              interleukin-4-mediated signaling pathway 3
              interleukin-5-mediated signaling pathway 2
              interleukin-6-mediated signaling pathway + 13
              interleukin-7-mediated signaling pathway 2
              interleukin-8-mediated signaling pathway 2
              interleukin-9-mediated signaling pathway 1
              leptin-mediated signaling pathway + 7
              macrophage colony-stimulating factor signaling pathway 4
              macrophage migration inhibitory factor signaling pathway + 1
              negative regulation of cytokine-mediated signaling pathway + 30
              oncostatin-M-mediated signaling pathway 3
              positive regulation of cytokine-mediated signaling pathway + 22
              prolactin signaling pathway 2
              regulation of cytokine-mediated signaling pathway + 104
              tumor necrosis factor-mediated signaling pathway + 42
              type I interferon-mediated signaling pathway + 103
Path 2
Term Annotations click to browse term
  biological_process 117121
    cellular process 80039
      single-organism cellular process 49274
        cellular response to stimulus 17850
          cellular response to chemical stimulus 4438
            cellular response to organic substance 3353
              cellular response to cytokine stimulus 766
                cytokine-mediated signaling pathway 600
                  Kit signaling pathway + 2
                  adiponectin-mediated signaling pathway 4
                  chemokine-mediated signaling pathway + 32
                  ciliary neurotrophic factor-mediated signaling pathway 5
                  erythropoietin-mediated signaling pathway 3
                  granulocyte colony-stimulating factor signaling pathway 0
                  granulocyte-macrophage colony-stimulating factor signaling pathway 0
                  interferon-gamma-mediated signaling pathway + 95
                  interleukin-1-mediated signaling pathway + 16
                  interleukin-11-mediated signaling pathway 0
                  interleukin-12-mediated signaling pathway 3
                  interleukin-13-mediated signaling pathway 0
                  interleukin-15-mediated signaling pathway 1
                  interleukin-17-mediated signaling pathway 0
                  interleukin-17A-mediated signaling pathway 0
                  interleukin-18-mediated signaling pathway + 0
                  interleukin-2-mediated signaling pathway 3
                  interleukin-21-mediated signaling pathway 1
                  interleukin-23-mediated signaling pathway 2
                  interleukin-27-mediated signaling pathway + 1
                  interleukin-3-mediated signaling pathway 2
                  interleukin-32-mediated signaling pathway 0
                  interleukin-33-mediated signaling pathway 0
                  interleukin-34-mediated signaling pathway 0
                  interleukin-35-mediated signaling pathway + 0
                  interleukin-4-mediated signaling pathway 3
                  interleukin-5-mediated signaling pathway 2
                  interleukin-6-mediated signaling pathway + 13
                  interleukin-7-mediated signaling pathway 2
                  interleukin-8-mediated signaling pathway 2
                  interleukin-9-mediated signaling pathway 1
                  leptin-mediated signaling pathway + 7
                  macrophage colony-stimulating factor signaling pathway 4
                  macrophage migration inhibitory factor signaling pathway + 1
                  negative regulation of cytokine-mediated signaling pathway + 30
                  oncostatin-M-mediated signaling pathway 3
                  positive regulation of cytokine-mediated signaling pathway + 22
                  prolactin signaling pathway 2
                  regulation of cytokine-mediated signaling pathway + 104
                  tumor necrosis factor-mediated signaling pathway + 42
                  type I interferon-mediated signaling pathway + 103
paths to the root

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