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ONTOLOGY REPORT - ANNOTATIONS

Term:follicle-stimulating hormone activity
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Accession:GO:0016913 term browser browse the term
Definition:The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.
Synonyms:exact_synonym: FSH activity;   follitropin activity


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follicle-stimulating hormone activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cga glycoprotein hormones, alpha polypeptide enables ISO
ISS
IBA		 (PMID:24692546), (PMID:2494176)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:2494176 PMID:24692546 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Fshb follicle stimulating hormone subunit beta enables TAS
ISO
ISS
IBA		 (PMID:11514332), (PMID:24692546), (PMID:2494176)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:2494176 PMID:11514332 PMID:24692546 PMID:2504572 GO_REF:0000024 GO_REF:0000033, RGD:61788 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
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  molecular_function 21010
    binding 18037
      protein binding 14764
        signaling receptor binding 1640
          receptor ligand activity 495
            hormone activity 137
              follicle-stimulating hormone activity 2
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