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Term:protein processing
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Accession:GO:0016485 term browser browse the term
Definition:Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
Synonyms:exact_synonym: protein maturation by peptide bond cleavage;   protein maturation by peptide bond hydrolysis
 related_synonym: peptidolysis during protein maturation;   protein maturation by proteolysis
 alt_id: GO:0051605

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protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 GBrowse link ISO 10 36,168,655 36,377,640 RGD:1624291 RGD
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 GBrowse link IEA 10 36,168,655 36,377,640 RGD:1600115 ENSEMBL
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 GBrowse link ISO 14 19,756,887 19,963,451 RGD:1624291 RGD
G Adamts3 ADAM metallopeptidase with thrombospondin type 1, motif 3 GBrowse link IEA 14 19,756,887 19,963,451 RGD:1600115 ENSEMBL
G Aph1a anterior pharynx defective 1 homolog A (C. elegans) GBrowse link ISO 2 190,679,692 190,683,202 RGD:1624291 RGD
G Aph1a anterior pharynx defective 1 homolog A (C. elegans) GBrowse link IEA 2 190,679,692 190,683,202 RGD:1600115 ENSEMBL
G Aph1b anterior pharynx defective 1 homolog B (C. elegans) GBrowse link ISO 8 71,122,681 71,143,726 RGD:1624291 RGD
G Aph1b anterior pharynx defective 1 homolog B (C. elegans) GBrowse link IEA 8 71,122,681 71,143,726 RGD:1600115 InterPro
G C2cd3 C2 calcium-dependent domain containing 3 GBrowse link ISO 1 157,774,397 157,892,744 RGD:1624291 RGD
G Casp1 caspase 1 GBrowse link ISO 8 2,027,976 2,036,872 RGD:1624291 RGD
G Casp1 caspase 1 GBrowse link ISO 8 2,027,976 2,036,872 RGD:1624291 RGD
G Casp1 caspase 1 GBrowse link ISO 8 2,027,976 2,036,872 RGD:1624291 RGD
G Casp1 caspase 1 GBrowse link ISO 8 2,027,976 2,036,872 RGD:1624291 RGD
G Casp1 caspase 1 GBrowse link IEA 8 2,027,976 2,036,872 RGD:1600115 ENSEMBL
G Casp2 caspase 2 GBrowse link ISO 4 70,029,728 70,047,164 RGD:1624291 RGD
G Casp2 caspase 2 GBrowse link IEA 4 70,029,728 70,047,164 RGD:1600115 ENSEMBL
G Casp3 caspase 3 GBrowse link ISO 16 48,944,226 48,962,420 RGD:1624291 RGD
G Casp7 caspase 7 GBrowse link ISO 1 262,689,300 262,721,591 RGD:1624291 RGD
G Cln3 ceroid-lipofuscinosis, neuronal 3 GBrowse link ISO 1 185,713,096 185,724,375 RGD:1624291 RGD
G Cln3 ceroid-lipofuscinosis, neuronal 3 GBrowse link IEA 1 185,713,096 185,724,375 RGD:1600115 ENSEMBL
G Corin corin, serine peptidase GBrowse link IMP 14 38,109,932 38,339,631 RGD:1626336 RGD
G Cpe carboxypeptidase E IDA RGD:1626225 RGD
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 GBrowse link ISO 8 3,826,843 4,072,644 RGD:1624291 RGD
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 GBrowse link ISO 8 3,826,843 4,072,644 RGD:1624291 RGD
G Ece1 endothelin converting enzyme 1 GBrowse link IDA 5 156,635,656 156,735,783 RGD:728596 RGD
G Ece1 endothelin converting enzyme 1 GBrowse link ISO 5 156,635,656 156,735,783 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G Fkrp fukutin related protein GBrowse link ISO 1 77,133,884 77,139,485 RGD:1624291 RGD
G Fkrp fukutin related protein GBrowse link IEA 1 77,133,884 77,139,485 RGD:1600115 ENSEMBL
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link IDA 1 136,209,969 136,222,057 RGD:633598 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link IMP 1 136,209,969 136,222,057 RGD:1582619 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Gli3 GLI family zinc finger 3 GBrowse link IDA 17 57,594,102 57,867,710 RGD:2290270 MGI
G Gli3 GLI family zinc finger 3 GBrowse link ISO 17 57,594,102 57,867,710 RGD:1624291 RGD
G Ift172 intraflagellar transport 172 homolog (Chlamydomonas) ISO RGD:1624291 RGD
G Ift88 intraflagellar transport 88 homolog (Chlamydomonas) GBrowse link ISO 15 36,468,007 36,560,959 RGD:1624291 RGD
G Ift88 intraflagellar transport 88 homolog (Chlamydomonas) GBrowse link IEA 15 36,468,007 36,560,959 RGD:1600115 ENSEMBL
G Klk13 kallikrein related-peptidase 13 GBrowse link ISO 1 94,133,589 94,145,208 RGD:1624291 RGD
G Klk13 kallikrein related-peptidase 13 GBrowse link IEA 1 94,133,589 94,145,208 RGD:1600115 ENSEMBL
G LOC691658 similar to anterior pharynx defective 1b homolog GBrowse link IEA 8 71,088,414 71,106,232 RGD:1600115 InterPro
G Lonp2 lon peptidase 2, peroxisomal GBrowse link IBA 19 21,785,263 21,838,495 RGD:1600115 RefGenome
G Metap2 methionyl aminopeptidase 2 GBrowse link ISO 7 30,974,071 31,001,641 RGD:1624291 RGD
G Metap2 methionyl aminopeptidase 2 GBrowse link ISS 7 30,974,071 31,001,641 RGD:1600115 HGNC
G Myc myelocytomatosis oncogene GBrowse link ISO 7 98,953,142 98,958,060 RGD:1624291 RGD
G Myc myelocytomatosis oncogene GBrowse link IEA 7 98,953,142 98,958,060 RGD:1600115 ENSEMBL
G Ncstn nicastrin GBrowse link IEP 13 88,060,484 88,076,493 RGD:724403 RGD
G Ncstn nicastrin GBrowse link ISO 13 88,060,484 88,076,493 RGD:1624291 RGD
G Ncstn nicastrin GBrowse link ISS 13 88,060,484 88,076,493 RGD:1600115 UniProtKB
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 GBrowse link ISO 12 35,074,025 35,117,152 RGD:1624291 RGD
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 GBrowse link IEA 12 35,074,025 35,117,152 RGD:1600115 ENSEMBL
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link ISO 2 1,923,309 1,970,238 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk6 proprotein convertase subtilisin/kexin type 6 GBrowse link ISO 1 120,324,843 120,476,913 RGD:1624291 RGD
G Pcsk6 proprotein convertase subtilisin/kexin type 6 GBrowse link ISO 1 120,324,843 120,476,913 RGD:1624291 RGD
G Pcsk6 proprotein convertase subtilisin/kexin type 6 GBrowse link ISO 1 120,324,843 120,476,913 RGD:1624291 RGD
G Pcsk9 proprotein convertase subtilisin/kexin type 9 GBrowse link IDA 5 127,501,476 127,524,289 RGD:1582518 RGD
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 GBrowse link IMP 18 22,495,197 22,579,656 RGD:628447 RGD
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma GBrowse link ISO 6 135,204,405 135,299,068 RGD:1624291 RGD
G Psen1 presenilin 1 GBrowse link IDA 6 107,737,543 107,776,357 RGD:1358417 RGD
G Psen1 presenilin 1 GBrowse link ISO 6 107,737,543 107,776,357 RGD:1624291 RGD
G Psen1 presenilin 1 GBrowse link ISO 6 107,737,543 107,776,357 RGD:1624291 RGD
G Psen1 presenilin 1 GBrowse link ISO 6 107,737,543 107,776,357 RGD:1624291 RGD
G Psen1 presenilin 1 GBrowse link ISS 6 107,737,543 107,776,357 RGD:1600115 UniProtKB
G Psen2 presenilin 2 GBrowse link ISO 13 95,934,674 95,951,836 RGD:1624291 RGD
G Psen2 presenilin 2 GBrowse link ISO 13 95,934,674 95,951,836 RGD:1624291 RGD
G Psen2 presenilin 2 GBrowse link IEA 13 95,934,674 95,951,836 RGD:1600115 ENSEMBL
G Psenen presenilin enhancer 2 homolog (C. elegans) GBrowse link ISO 1 85,607,051 85,608,248 RGD:1624291 RGD
G Ptch1 patched 1 GBrowse link ISO 17 7,088,234 7,142,459 RGD:1624291 RGD
G Ptch1 patched 1 GBrowse link ISS 17 7,088,234 7,142,459 RGD:1600115 UniProtKB
G Pthlh parathyroid hormone-like hormone GBrowse link ISO 4 184,887,702 184,898,841 RGD:1624291 RGD
G Rnpep arginyl aminopeptidase (aminopeptidase B) GBrowse link NAS 13 48,267,923 48,286,295 RGD:2325944 UniProtKB
G Srgn serglycin GBrowse link ISO 20 29,746,729 29,761,072 RGD:1624291 RGD
G Srgn serglycin GBrowse link ISS 20 29,746,729 29,761,072 RGD:1600115 UniProtKB
G Tysnd1 trypsin domain containing 1 GBrowse link ISS 20 29,062,966 29,068,684 RGD:1600115 UniProtKB
G Tysnd1 trypsin domain containing 1 GBrowse link ISO 20 29,062,966 29,068,684 RGD:1624291 RGD
G Xpnpep3 X-prolyl aminopeptidase (aminopeptidase P) 3, putative GBrowse link IEA 7 119,729,428 119,779,023 RGD:1600115 ENSEMBL
G Xpnpep3 X-prolyl aminopeptidase (aminopeptidase P) 3, putative GBrowse link ISO 7 119,729,428 119,779,023 RGD:1624291 RGD
activation of plasma proteins involved in acute inflammatory response term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link ISO 2 218,371,050 218,382,645 RGD:1624291 RGD
G F3 coagulation factor III (thromboplastin, tissue factor) GBrowse link IEA 2 218,371,050 218,382,645 RGD:1600115 ENSEMBL
angiotensin maturation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 GBrowse link IDA X 22,264,078 22,291,988 RGD:5132599 RGD
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 GBrowse link ISO X 22,264,078 22,291,988 RGD:1624291 RGD
G Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 GBrowse link ISO X 22,264,078 22,291,988 RGD:1624291 RGD
G Ren renin GBrowse link IDA 13 46,262,936 46,275,213 RGD:5132599 RGD
G Ren renin GBrowse link ISO 13 46,262,936 46,275,213 RGD:1624291 RGD
G Ren renin GBrowse link ISO 13 46,262,936 46,275,213 RGD:1624291 RGD
CAAX-box protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Rce1 RCE1 homolog, prenyl protein protease (S. cerevisiae) GBrowse link ISS 1 207,213,714 207,216,814 RGD:1600115 UniProtKB
G Rce1 RCE1 homolog, prenyl protein protease (S. cerevisiae) GBrowse link IEA 1 207,213,714 207,216,814 RGD:1600115 ENSEMBL
G Rce1 RCE1 homolog, prenyl protein protease (S. cerevisiae) GBrowse link ISO 1 207,213,714 207,216,814 RGD:1624291 RGD
G Zmpste24 zinc metallopeptidase STE24 GBrowse link IEA 5 141,644,119 141,677,211 RGD:1600115 InterPro
endothelin maturation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ece1 endothelin converting enzyme 1 GBrowse link ISO 5 156,635,656 156,735,783 RGD:1624291 RGD
enkephalin processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cpe carboxypeptidase E IDA RGD:6483103 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IEA 3 131,925,648 132,256,178 RGD:1600115 ENSEMBL
Factor XII activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
insulin processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cpe carboxypeptidase E ISO RGD:1624291 RGD
G Cpe carboxypeptidase E IDA RGD:1626225 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IEA 3 131,925,648 132,256,178 RGD:1600115 ENSEMBL
intein-mediated protein splicing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Dhh desert hedgehog GBrowse link IEA 7 137,666,984 137,672,479 RGD:1600115 InterPro
G Ihh Indian hedgehog GBrowse link IEA 9 74,287,115 74,293,332 RGD:1600115 InterPro
G Shh sonic hedgehog GBrowse link IEA 4 2,200,504 2,209,657 RGD:1600115 InterPro
islet amyloid polypeptide processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IMP 3 131,925,648 132,256,178 BHF-UCL
mitochondrial protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Afg3l1 AFG3(ATPase family gene 3)-like 1 (S. cerevisiae) GBrowse link ISO 19 53,794,261 53,821,667 RGD:1624291 RGD
G Afg3l2 AFG3 ATPase family member 3-like 2 (S. cerevisiae) GBrowse link ISO 18 63,930,652 63,976,211 RGD:1624291 RGD
G Afg3l2 AFG3 ATPase family member 3-like 2 (S. cerevisiae) GBrowse link IEA 18 63,930,652 63,976,211 RGD:1600115 ENSEMBL
G Oma1 zinc metallopeptidase homolog (S. cerevisiae) GBrowse link ISO 5 124,261,197 124,314,715 RGD:1624291 RGD
G Oma1 zinc metallopeptidase homolog (S. cerevisiae) GBrowse link IEA 5 124,261,197 124,314,715 RGD:1600115 ENSEMBL
G Stoml2 stomatin (Epb7.2)-like 2 GBrowse link ISS 5 59,518,467 59,522,064 RGD:1600115 UniProtKB
negative regulation of activation of membrane attack complex term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd59 CD59 molecule, complement regulatory protein GBrowse link IDA 3 89,243,600 89,245,129 RGD:1600482 RGD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link ISO 3 89,243,600 89,245,129 RGD:1624291 RGD
negative regulation of complement activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd46 CD46 molecule, complement regulatory protein GBrowse link IDA 13 110,972,812 111,003,407 RGD:2293559 RGD
G Cd55 Cd55 molecule GBrowse link IDA 13 43,322,246 43,348,334 RGD:2326180 RGD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link ISO 3 89,243,600 89,245,129 RGD:1624291 RGD
G Cr1l complement component (3b/4b) receptor 1-like GBrowse link IMP 13 111,010,296 111,057,427 RGD:625470 RGD
G Cr1l complement component (3b/4b) receptor 1-like GBrowse link ISO 13 111,010,296 111,057,427 RGD:1624291 RGD
G Masp1 mannan-binding lectin serine peptidase 1 GBrowse link ISO 11 79,532,504 79,602,755 RGD:1624291 RGD
G Masp1 mannan-binding lectin serine peptidase 1 GBrowse link IEA 11 79,532,504 79,602,755 RGD:1600115 ENSEMBL
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G A2m alpha-2-macroglobulin GBrowse link ISO 4 158,103,711 158,153,423 RGD:1624291 RGD
G Serping1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 GBrowse link ISO 3 67,968,808 67,978,102 RGD:1624291 RGD
G Serping1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 GBrowse link ISS 3 67,968,808 67,978,102 RGD:1600115 UniProtKB
negative regulation of plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cpb2 carboxypeptidase B2 (plasma) GBrowse link IMP 15 56,104,920 56,154,321 RGD:7243115 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IEA 12 20,931,996 20,942,374 RGD:1600115 ENSEMBL
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link ISO 9 79,091,414 79,166,330 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link ISO 9 79,091,414 79,166,330 RGD:1624291 RGD
G Serpine2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 GBrowse link IEA 9 79,091,414 79,166,330 RGD:1600115 ENSEMBL
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link ISO 10 62,748,116 62,756,200 RGD:1624291 RGD
G Serpinf2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 GBrowse link IEA 10 62,748,116 62,756,200 RGD:1600115 ENSEMBL
G Thbs1 thrombospondin 1 ISO RGD:1624291 RGD
negative regulation of protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Chac1 ChaC, cation transport regulator homolog 1 (E. coli) GBrowse link ISS 3 105,869,762 105,873,332 RGD:1600115 UniProtKB
G Chac1 ChaC, cation transport regulator homolog 1 (E. coli) GBrowse link ISO 3 105,869,762 105,873,332 RGD:1624291 RGD
G Glg1 golgi glycoprotein 1 GBrowse link ISO 19 41,082,324 41,176,959 RGD:1624291 RGD
G Glg1 golgi glycoprotein 1 GBrowse link IEA 19 41,082,324 41,176,959 RGD:1600115 ENSEMBL
G Mdm2 p53 E3 ubiquitin protein ligase GBrowse link IMP 7 56,996,694 57,020,926 RGD:2317364 RGD
peptide hormone processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Corin corin, serine peptidase GBrowse link ISO 14 38,109,932 38,339,631 RGD:1624291 RGD
G Corin corin, serine peptidase GBrowse link ISO 14 38,109,932 38,339,631 RGD:1624291 RGD
G Corin corin, serine peptidase GBrowse link ISO 14 38,109,932 38,339,631 RGD:1624291 RGD
G Corin corin, serine peptidase GBrowse link ISO 14 38,109,932 38,339,631 RGD:1624291 RGD
G Corin corin, serine peptidase GBrowse link ISO 14 38,109,932 38,339,631 RGD:1624291 RGD
G Corin corin, serine peptidase GBrowse link ISS 14 38,109,932 38,339,631 RGD:1600115 UniProtKB
G Cpe carboxypeptidase E TAS RGD:727682 RGD
G Ece1 endothelin converting enzyme 1 GBrowse link ISO 5 156,635,656 156,735,783 RGD:1624291 RGD
G Ece2 endothelin-converting enzyme 2 GBrowse link TAS 11 82,492,975 82,507,876 RGD:1303943 RGD
G Ece2 endothelin-converting enzyme 2 GBrowse link ISO 11 82,492,975 82,507,876 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link IEA 1 136,209,969 136,222,057 RGD:1600115 ENSEMBL
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link IDA 2 1,923,309 1,970,238 RGD:2308913 RGD
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link IMP 2 1,923,309 1,970,238 RGD:1601276 RGD
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link ISO 2 1,923,309 1,970,238 RGD:1624291 RGD
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link ISO 2 1,923,309 1,970,238 RGD:1624291 RGD
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor GBrowse link ISO X 26,614,585 26,618,027 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IMP 3 131,925,648 132,256,178 RGD:1601276 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link IEA 1 220,961,912 221,405,907 RGD:1600115 ENSEMBL
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link IEA 1 220,961,912 221,405,907 RGD:1600115 ENSEMBL
G Pcsk6 proprotein convertase subtilisin/kexin type 6 GBrowse link IEP 1 120,324,843 120,476,913 RGD:729476 RGD
G Pcsk6 proprotein convertase subtilisin/kexin type 6 GBrowse link ISO 1 120,324,843 120,476,913 RGD:1624291 RGD
G Scg5 secretogranin V (7B2 protein) GBrowse link ISO 3 99,629,194 99,674,523 RGD:1624291 RGD
G Scg5 secretogranin V (7B2 protein) GBrowse link IEA 3 99,629,194 99,674,523 RGD:1600115 ENSEMBL
G Scg5 secretogranin V (7B2 protein) GBrowse link ISS 3 99,629,194 99,674,523 RGD:1600115 UniProtKB
plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Apoh apolipoprotein H (beta-2-glycoprotein I) GBrowse link ISO 10 97,725,088 97,739,213 RGD:1624291 RGD
G Apoh apolipoprotein H (beta-2-glycoprotein I) GBrowse link IEA 10 97,725,088 97,739,213 RGD:1600115 ENSEMBL
G Dhcr24 24-dehydrocholesterol reductase GBrowse link ISO 5 127,637,438 127,662,621 RGD:1624291 RGD
G Dhcr24 24-dehydrocholesterol reductase GBrowse link IEA 5 127,637,438 127,662,621 RGD:1600115 ENSEMBL
G F11 coagulation factor XI GBrowse link ISO 16 50,276,330 50,298,903 RGD:1624291 RGD
G F11 coagulation factor XI GBrowse link IEA 16 50,276,330 50,298,903 RGD:1600115 ENSEMBL
G Hist1h2ba histone cluster 1, H2ba GBrowse link ISO 17 48,290,185 48,290,654 RGD:1624291 RGD
G Hist1h2ba histone cluster 1, H2ba GBrowse link IEA 17 48,290,185 48,290,654 RGD:1600115 ENSEMBL
G Klkb1 kallikrein B, plasma 1 GBrowse link ISO 16 50,248,935 50,272,279 RGD:1624291 RGD
G Klkb1 kallikrein B, plasma 1 GBrowse link IEA 16 50,248,935 50,272,279 RGD:1600115 ENSEMBL
G Plat plasminogen activator, tissue GBrowse link ISO 16 73,711,323 73,736,328 RGD:1624291 RGD
G Plat plasminogen activator, tissue GBrowse link IEA 16 73,711,323 73,736,328 RGD:1600115 ENSEMBL
positive regulation of activation of membrane attack complex term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G C3 complement component 3 ISO RGD:1624291 RGD
G C6 complement component 6 GBrowse link ISO 2 53,691,290 53,764,539 RGD:1624291 RGD
positive regulation of complement activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G C6 complement component 6 GBrowse link ISO 2 53,691,290 53,764,539 RGD:1624291 RGD
G Mbl2 mannose-binding lectin (protein C) 2 GBrowse link IDA 1 233,978,931 233,983,824 RGD:4889148 RGD
positive regulation of plasminogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Clec3b C-type lectin domain family 3, member B ISO RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
G Hpn hepsin GBrowse link ISO 1 86,145,615 86,161,091 RGD:1624291 RGD
G Hpn hepsin GBrowse link ISS 1 86,145,615 86,161,091 RGD:1600115 UniProtKB
G LOC100912012 tetranectin-like ISS RGD:1600115 UniProtKB
G Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein GBrowse link ISO 1 233,030,393 233,042,659 RGD:1624291 RGD
G Plgrkt plasminogen receptor, C-terminal lysine transmembrane protein GBrowse link IEA 1 233,030,393 233,042,659 RGD:1600115 ENSEMBL
positive regulation of protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Astl astacin-like metalloendopeptidase (M12 family) GBrowse link IEA 3 114,845,320 114,861,053 RGD:1600115 ENSEMBL
G Cntn2 contactin 2 (axonal) GBrowse link ISO 13 45,399,915 45,428,789 RGD:1624291 RGD
G Cntn2 contactin 2 (axonal) GBrowse link IEA 13 45,399,915 45,428,789 RGD:1600115 ENSEMBL
G LOC100361444 rCG31799-like GBrowse link ISO 8 20,948,070 20,950,087 RGD:1624291 RGD
G Nkd2 naked cuticle homolog 2 (Drosophila) GBrowse link IEA 1 30,252,093 30,278,933 RGD:1600115 ENSEMBL
G Nkd2 naked cuticle homolog 2 (Drosophila) GBrowse link ISO 1 30,252,093 30,278,933 RGD:1624291 RGD
G Rhbdd1 rhomboid domain containing 1 GBrowse link ISO 9 81,685,464 81,778,714 RGD:1624291 RGD
G Rhbdd1 rhomboid domain containing 1 GBrowse link ISS 9 81,685,464 81,778,714 RGD:1600115 UniProtKB
protein autoprocessing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Capn1 calpain 1, (mu/I) large subunit GBrowse link IC 1 208,620,286 208,645,007 RGD:1626249 RGD
G Capn1 calpain 1, (mu/I) large subunit GBrowse link IDA 1 208,620,286 208,645,007 RGD:2303057 RGD
G Capn2 calpain 2, (m/II) large subunit GBrowse link IC 13 98,473,367 98,524,463 RGD:1626249 RGD
G Capn2 calpain 2, (m/II) large subunit GBrowse link IDA 13 98,473,367 98,524,463 RGD:2303057 RGD
G Casp12 caspase 12 GBrowse link IDA 8 2,082,933 2,110,511 RGD:2311459 RGD
G Ctse cathepsin E GBrowse link IMP 13 44,582,911 44,605,241 RGD:2325171 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
G Fxn frataxin GBrowse link IEA 1 227,647,092 227,671,081 RGD:1600115 ENSEMBL
G Fxn frataxin GBrowse link ISO 1 227,647,092 227,671,081 RGD:1624291 RGD
G Parp1 poly (ADP-ribose) polymerase 1 GBrowse link IDA 13 96,309,670 96,341,486 RGD:1601081 RGD
G Pcsk1 proprotein convertase subtilisin/kexin type 1 GBrowse link IMP 2 1,923,309 1,970,238 RGD:2308914 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link ISO 3 131,925,648 132,256,178 RGD:1624291 RGD
G Pcsk2 proprotein convertase subtilisin/kexin type 2 GBrowse link IEA 3 131,925,648 132,256,178 RGD:1600115 ENSEMBL
G Pcsk9 proprotein convertase subtilisin/kexin type 9 GBrowse link IDA 5 127,501,476 127,524,289 RGD:1582518 RGD
G Pcsk9 proprotein convertase subtilisin/kexin type 9 GBrowse link ISO 5 127,501,476 127,524,289 RGD:1624291 RGD
protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Immp1l IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae) GBrowse link IEA 3 91,408,864 91,436,603 RGD:1600115 InterPro
G Immp2l IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) GBrowse link ISO 6 60,311,939 61,230,323 RGD:1624291 RGD
G Immp2l IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) GBrowse link IEA 6 60,311,939 61,230,323 RGD:1600115 InterPro
G Pmpcb peptidase (mitochondrial processing) beta GBrowse link TAS 4 8,746,904 8,759,681 RGD:729580 RGD
regulation of complement activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISS 10 57,881,783 57,886,434 RGD:1600115 UniProtKB
G C1qbp complement component 1, q subcomponent binding protein GBrowse link ISO 10 57,881,783 57,886,434 RGD:1624291 RGD
G Cd59 CD59 molecule, complement regulatory protein GBrowse link NAS 3 89,243,600 89,245,129 RGD:727654 RGD
G Cfh complement factor H GBrowse link IDA 13 53,252,249 53,355,987 RGD:628500 RGD
G Cfh complement factor H GBrowse link ISO 13 53,252,249 53,355,987 RGD:1624291 RGD
G Cr1l complement component (3b/4b) receptor 1-like GBrowse link ISO 13 111,010,296 111,057,427 RGD:1624291 RGD
regulation of complement activation, classical pathway term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cd55 Cd55 molecule GBrowse link ISO 13 43,322,246 43,348,334 RGD:1624291 RGD
regulation of protein processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Inpp5b inositol polyphosphate-5-phosphatase B GBrowse link ISO 5 144,070,183 144,134,613 RGD:1624291 RGD
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 GBrowse link ISO 3 87,108,483 87,275,069 RGD:1624291 RGD
G Rnf139 ring finger protein 139 GBrowse link ISO 7 95,659,052 95,661,624 RGD:1624291 RGD
G Rps6ka2 ribosomal protein S6 kinase polypeptide 2 GBrowse link ISO 1 47,424,106 47,560,373 RGD:1624291 RGD
signal peptide processing term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cln5 ceroid-lipofuscinosis, neuronal 5 GBrowse link ISO 15 87,080,071 87,089,784 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link ISO 1 136,209,969 136,222,057 RGD:1624291 RGD
G Furin furin (paired basic amino acid cleaving enzyme) GBrowse link IEA 1 136,209,969 136,222,057 RGD:1600115 ENSEMBL
G Lonp2 lon peptidase 2, peroxisomal GBrowse link IEA 19 21,785,263 21,838,495 RGD:1600115 ENSEMBL
G MGC109340 similar to Microsomal signal peptidase 23 kDa subunit (SPase 22 kDa subunit) (SPC22/23) GBrowse link IEA X 123,250,878 123,253,563 RGD:1600115 InterPro
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link ISO 1 220,961,912 221,405,907 RGD:1624291 RGD
G Pcsk5 proprotein convertase subtilisin/kexin type 5 GBrowse link IEA 1 220,961,912 221,405,907 RGD:1600115 ENSEMBL
G Sec11a SEC11 homolog A (S. cerevisiae) GBrowse link IEA 1 137,109,466 137,126,782 RGD:1600115 InterPro
G Sec11c SEC11 homolog C (S. cerevisiae) GBrowse link IEA 18 62,096,585 62,112,929 RGD:1600115 InterPro
G Spcs1 signal peptidase complex subunit 1 homolog (S. cerevisiae) GBrowse link IEA 16 6,427,296 6,428,864 RGD:1600115 InterPro
G Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) GBrowse link IEA 1 157,197,975 157,217,400 RGD:1600115 InterPro
G Spcs3 signal peptidase complex subunit 3 homolog (S. cerevisiae) GBrowse link IEA 16 40,215,903 40,221,337 RGD:1600115 InterPro
trypsinogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Cuzd1 CUB and zona pellucida-like domains 1 GBrowse link ISO 1 190,887,527 190,900,654 RGD:1624291 RGD
G Cuzd1 CUB and zona pellucida-like domains 1 GBrowse link ISS 1 190,887,527 190,900,654 RGD:1600115 UniProtKB
zymogen activation term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ctsh cathepsin H GBrowse link ISO 8 94,971,689 94,990,434 RGD:1624291 RGD
G Ctsh cathepsin H GBrowse link ISO 8 94,971,689 94,990,434 RGD:1624291 RGD
G Ctsh cathepsin H GBrowse link ISS 8 94,971,689 94,990,434 RGD:1600115 UniProtKB
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link ISO 17 15,251,611 15,259,583 RGD:1624291 RGD
G F12 coagulation factor XII (Hageman factor) GBrowse link IEA 17 15,251,611 15,259,583 RGD:1600115 ENSEMBL
G LOC679835 similar to Anionic trypsin II precursor (Pretrypsinogen II) GBrowse link ISO 4 69,144,579 69,149,045 RGD:1624291 RGD
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) GBrowse link ISO 15 32,493,852 32,503,077 RGD:1624291 RGD
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) GBrowse link IEA 15 32,493,852 32,503,077 RGD:1600115 ENSEMBL
G Prss12 protease, serine, 12 neurotrypsin (motopsin) GBrowse link ISO 2 220,194,590 220,254,502 RGD:1624291 RGD
G Prss12 protease, serine, 12 neurotrypsin (motopsin) GBrowse link IEA 2 220,194,590 220,254,502 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    metabolic process 36390
      primary metabolic process 29834
        protein metabolic process 10746
          protein maturation 283
            protein processing 267
              CAAX-box protein processing 4
              Notch receptor processing, ligand-independent 0
              activation of plasma proteins involved in acute inflammatory response + 4
              dibasic protein processing + 0
              mitochondrial protein processing + 10
              negative regulation of protein processing + 29
              peptide bond cleavage involved in epidermal growth factor receptor ligand maturation 0
              peptide hormone processing + 46
              positive regulation of protein processing + 22
              protein autoprocessing 16
              protein initiator methionine removal involved in protein maturation 0
              protein processing in phagocytic vesicle 0
              protein splicing + 3
              regulation of protein processing + 62
              signal peptide processing + 12
              sterol regulatory element binding protein cleavage + 0
              vacuolar protein processing 0
              viral protein processing 0
              zymogen activation + 46
Path 2
Term Annotations click to browse term
  biological_process 135967
    metabolic process 36390
      organic substance metabolic process 32723
        macromolecule metabolic process 25172
          gene expression 12130
            protein maturation 283
              protein processing 267
                CAAX-box protein processing 4
                Notch receptor processing, ligand-independent 0
                activation of plasma proteins involved in acute inflammatory response + 4
                dibasic protein processing + 0
                mitochondrial protein processing + 10
                negative regulation of protein processing + 29
                peptide bond cleavage involved in epidermal growth factor receptor ligand maturation 0
                peptide hormone processing + 46
                positive regulation of protein processing + 22
                protein autoprocessing 16
                protein initiator methionine removal involved in protein maturation 0
                protein processing in phagocytic vesicle 0
                protein splicing + 3
                regulation of protein processing + 62
                signal peptide processing + 12
                sterol regulatory element binding protein cleavage + 0
                vacuolar protein processing 0
                viral protein processing 0
                zymogen activation + 46
paths to the root

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