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ONTOLOGY REPORT - ANNOTATIONS


Term:coenzyme A biosynthetic process
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Accession:GO:0015937 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
Synonyms:exact_synonym: CoA biosynthesis;   coenzyme A anabolism;   coenzyme A biosynthesis;   coenzyme A formation;   coenzyme A synthesis
 alt_id: GO:0006764
 xref: MetaCyc:COA-PWY;   MetaCyc:PANTOSYN-PWY;   MetaCyc:PWY-4221



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coenzyme A biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat1 acetyl-CoA acetyltransferase 1 involved_in ISO (PMID:17371050) RGD PMID:17371050 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acot7 acyl-CoA thioesterase 7 involved_in ISO
IEA
(PMID:10578051)
GO_REF:0000107
RGD
Ensembl
PMID:10578051 GO_REF:0000107 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
JBrowse link
G Coasy Coenzyme A synthase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:11923312)
GO_REF:0000033
(PMID:11980892)
RGD
GO_Central
PMID:11923312 PMID:11980892 GO_REF:0000033 NCBI chr10:86,014,566...86,018,849
Ensembl chr10:86,014,597...86,018,841
JBrowse link
G Dcakd dephospho-CoA kinase domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054
JBrowse link
G Pank1 pantothenate kinase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:2176050|MGI:4462018 (PMID:20559429), (PMID:22815849)
MGI:1921700 (PMID:10625688), (PMID:22815849)
GO_Central
RGD
PMID:10625688 PMID:20559429 PMID:22815849 GO_REF:0000033 NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
JBrowse link
G Pank2 pantothenate kinase 2 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1922985|MGI:3514020 (PMID:22815849), (PMID:24316510)
MGI:2176050|MGI:5446719 (PMID:22815849)
GO_Central
RGD
PMID:22815849 PMID:24316510 GO_REF:0000033 NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320
JBrowse link
G Pank3 pantothenate kinase 3 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:20797618), (PMID:30927326)
GO_REF:0000033
(PMID:16040613)
RGD
GO_Central
PMID:16040613 PMID:20797618 PMID:30927326 GO_REF:0000033 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Pank4 pantothenate kinase 4 involved_in IEA
IBA
GO_REF:0000104
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000104 NCBI chr 5:165,525,340...165,542,139
Ensembl chr 5:165,525,402...165,542,135
JBrowse link
G Ppcdc phosphopantothenoylcysteine decarboxylase involved_in ISO
IBA
(PMID:11923312)
GO_REF:0000033
RGD
GO_Central
PMID:11923312 GO_REF:0000033 NCBI chr 8:57,815,195...57,842,863
Ensembl chr 8:57,815,195...58,000,570
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase involved_in ISO
IBA
(PMID:11923312), (PMID:29754768)
GO_REF:0000033
RGD
GO_Central
PMID:11923312 PMID:29754768 GO_REF:0000033 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:29,047,793...29,094,209
Ensembl chr20:29,047,796...29,094,084
JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        organic cyclic compound metabolic process 6260
          purine-containing compound metabolic process 607
            purine nucleoside bisphosphate metabolic process 118
              coenzyme A metabolic process 19
                coenzyme A biosynthetic process 12
                  regulation of coenzyme A biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        organic cyclic compound metabolic process 6260
          nucleobase-containing compound metabolic process 5743
            nucleobase-containing small molecule metabolic process 713
              nucleoside phosphate metabolic process 639
                nucleotide metabolic process 629
                  purine nucleotide metabolic process 572
                    purine nucleotide biosynthetic process 212
                      purine ribonucleotide biosynthetic process 181
                        coenzyme A biosynthetic process 12
                          regulation of coenzyme A biosynthetic process 0
paths to the root