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ONTOLOGY REPORT - ANNOTATIONS


Term:ABC-type bile acid transporter activity
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Accession:GO:0015432 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.
Synonyms:narrow_synonym: bile acid porter activity;   bile acid-exporting ATPase activity
 related_synonym: ATP-dependent bile acid transmembrane transporter activity;   ATPase-coupled bile acid transmembrane transporter activity
 xref: RHEA:50048;   Reactome:R-HSA-194153 "ABCC3 transports bile salts from cytosol to extracellular region";   Reactome:R-HSA-5678517 "Defective ABCB11 does not transport bile salts from cytosol to extracellular region";   TC:3.A.1.207.2;   reactome:R-HSA-193362 "ABCB11 transports bile salts from cytosol to extracellular region"



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ABC-type bile acid transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 enables IMP
IEA
ISO
ISS
IDA
IBA
PMID:15901796
GO_REF:0000107
(PMID:15791618), (PMID:15901796), (PMID:18985798), (PMID:32203132)
(PMID:18985798)
GO_REF:0000024
GO_REF:0000033
Ensembl
RGD
UniProt
GO_Central
PMID:15791618 PMID:15901796 PMID:18985798 PMID:32203132 PMID:15901796 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:1598579, RGD:30309919 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 enables IDA PMID:10644759 UniProt PMID:10644759 RGD:40902972 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 enables ISS
ISO
IEA
GO_REF:0000024
(PMID:16282361)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:16282361 GO_REF:0000024 GO_REF:0000107 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20890
    ATP-dependent activity 631
      ATPase-coupled transmembrane transporter activity 117
        ATPase-coupled lipid transmembrane transporter activity 7
          ABC-type bile acid transporter activity 3
Path 2
Term Annotations click to browse term
  molecular_function 20890
    transporter activity 1252
      transmembrane transporter activity 1157
        active transmembrane transporter activity 445
          primary active transmembrane transporter activity 152
            ATPase-coupled transmembrane transporter activity 117
              ATPase-coupled organic acid transmembrane transporter activity 3
                ATPase-coupled carboxylic acid transmembrane transporter activity 3
                  ATPase-coupled monocarboxylic acid transmembrane transporter activity 3
                    ABC-type bile acid transporter activity 3
paths to the root