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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium:proton antiporter activity
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Accession:GO:0015369 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
Synonyms:exact_synonym: calcium:hydrogen antiporter activity
 xref: RHEA:71799;   reactome:R-HSA-8949687 "LETM1 exchanges protons (mitochondrial intermembrane space) for calcium (mitochondrial matrix)"


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calcium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghitm growth hormone inducible transmembrane protein enables ISS
ISO		 GO_REF:0000024
(PMID:36321428)		 UniProt
RGD		 PMID:36321428 GO_REF:0000024 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:19797662)
(MGI:5643854|PMID:23716663), (MGI:5897526|PMID:27669901)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19797662 PMID:23716663 PMID:27669901 GO_REF:0000024 GO_REF:0000107 MGI:5643854 MGI:5897526 NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        active transmembrane transporter activity 448
          active monoatomic ion transmembrane transporter activity 257
            metal cation:monoatomic cation antiporter activity 41
              calcium:monoatomic cation antiporter activity 12
                calcium:proton antiporter activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        monoatomic ion transmembrane transporter activity 752
          monoatomic cation transmembrane transporter activity 631
            metal ion transmembrane transporter activity 461
              calcium ion transmembrane transporter activity 152
                calcium:monoatomic cation antiporter activity 12
                  calcium:proton antiporter activity 2
paths to the root