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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium:monoatomic cation antiporter activity
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Accession:GO:0015368 term browser browse the term
Definition:Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).
Synonyms:broad_synonym: calcium:cation antiporter activity
 xref: reactome:R-HSA-425822 "K+-independent Li+/Ca2+ exchanger transport"


show annotations for term's descendants           Sort by:
calcium:monoatomic cation antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc8a3 solute carrier family 8 member A3 enables ISO (PMID:8798769) RGD PMID:8798769 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
calcium, potassium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc24a1 solute carrier family 24 member 1 enables ISO
IBA
IEA		 (PMID:26631410)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:26631410 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:65,440,842...65,466,001
Ensembl chr 8:65,440,730...65,466,001 		JBrowse link
G Slc24a2 solute carrier family 24 member 2 enables IMP
IBA
IEA
ISO
IDA		 GO_REF:0000033
GO_REF:0000107
(PMID:10662833), (PMID:18166528), (PMID:26631410), (PMID:27093457)		 GO_Central
Ensembl
RGD		 PMID:10662833 PMID:18166528 PMID:26631410 PMID:27093457 PMID:12377762 More... GO_REF:0000033 GO_REF:0000107, RGD:730066, RGD:7175087 NCBI chr 5:101,497,916...101,741,840
Ensembl chr 5:101,502,278...101,739,337 		JBrowse link
G Slc24a3 solute carrier family 24 member 3 enables IDA
ISO
IBA
IEA		 (PMID:11294880)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
(PMID:26631410)		 RGD
GO_Central
TreeGrafter
Ensembl		 PMID:11294880 PMID:26631410 PMID:11294880 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:68852 NCBI chr 3:132,552,119...133,051,192
Ensembl chr 3:132,551,595...133,051,192 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 enables ISO
IBA		 (PMID:26631410)
GO_REF:0000033
(MGI:6718234|PMID:27093457)		 RGD
GO_Central		 PMID:26631410 PMID:27093457 GO_REF:0000033 MGI:6718234 NCBI chr 6:121,279,590...121,419,811
Ensembl chr 6:121,280,031...121,414,949 		JBrowse link
G Slc24a5 solute carrier family 24 member 5 enables ISO
IBA		 (PMID:18166528), (PMID:27093457)
GO_REF:0000033		 RGD
GO_Central		 PMID:18166528 PMID:27093457 GO_REF:0000033 NCBI chr 3:112,319,349...112,338,889
Ensembl chr 3:112,319,308...112,339,231 		JBrowse link
calcium:manganese antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30, member 10 enables ISO (PMID:30755481) RGD PMID:30755481 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc8a1 solute carrier family 8 member A1 enables IMP
ISO		 PMID:17215351
(PMID:1700476)		 RGD PMID:1700476 PMID:17215351 RGD:7175092 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 enables IMP
NAS
IDA		 PMID:8021246 SynGO PMID:8021246 PMID:8021246 PMID:8021246 RGD:730182, RGD:730182, RGD:730182 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 enables IMP
IDA
NAS		 PMID:8798769 SynGO PMID:8798769 PMID:8798769 PMID:8798769 RGD:730187, RGD:730187, RGD:730187 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
calcium:proton antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghitm growth hormone inducible transmembrane protein enables ISS
ISO		 GO_REF:0000024
(PMID:36321428)		 UniProt
RGD		 PMID:36321428 GO_REF:0000024 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Letm1 leucine zipper and EF-hand containing transmembrane protein 1 enables ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5643854|PMID:23716663), (MGI:5897526|PMID:27669901)
(PMID:19797662)		 UniProt
Ensembl
RGD		 PMID:19797662 PMID:23716663 PMID:27669901 GO_REF:0000024 GO_REF:0000107 MGI:5643854 MGI:5897526 NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904 		JBrowse link
calcium:sodium antiporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc8a1 solute carrier family 8 member A1 enables IDA
IBA
ISO
IEA
IMP		 GO_REF:0000033
(MGI:1927695|PMID:10967099)
GO_REF:0000117
(PMID:19481548)
PMID:11916852
(PMID:17962412)
(PMID:1374913), (PMID:25589784)		 GO_Central
RGD
UniProt		 PMID:1374913 PMID:10967099 PMID:17962412 PMID:19481548 PMID:25589784 More... GO_REF:0000033 GO_REF:0000117 MGI:1927695, RGD:730112, RGD:8553768, RGD:1581354, RGD:7175087, RGD:7175092, RGD:7241256, RGD:8554390 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 enables TAS
IBA
IEA
ISO
IDA		 GO_REF:0000033
GO_REF:0000117
(MGI:2664655|PMID:12818181)		 GO_Central
UniProt
RGD		 PMID:12818181 PMID:12377375 PMID:17343909 PMID:9486131 GO_REF:0000033 GO_REF:0000117 MGI:2664655, RGD:727449, RGD:7241257, RGD:2316984 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 enables IDA
IBA
IEA
ISO
EXP		 GO_REF:0000033
GO_REF:0000117
(MGI:3027331|PMID:14722618), (MGI:5013898|PMID:21593315)
PMID:24101730		 GO_Central
UniProt
RGD		 PMID:14722618 PMID:21593315 PMID:8798769 PMID:24101730 PMID:17343909 GO_REF:0000033 GO_REF:0000117 MGI:3027331 MGI:5013898, RGD:730187, RGD:12903236, RGD:7241257 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
G Slc8b1 solute carrier family 8 member B1 enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(MGI:4420691|PMID:20018762), (MGI:5902863|PMID:28445457), (PMID:14625281)
GO_REF:0000118
GO_REF:0000033
(PMID:15060069), (PMID:20018762), (PMID:23056385), (PMID:24898248), (PMID:28130126), (PMID:28219928)		 UniProt
RGD
TreeGrafter
GO_Central		 PMID:14625281 PMID:15060069 PMID:20018762 PMID:23056385 PMID:24898248 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:4420691 MGI:5902863, RGD:9685493 NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031 		JBrowse link
calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc8b1 solute carrier family 8 member B1 enables ISO
ISS		 (MGI:5902676|PMID:24067497), (MGI:5902863|PMID:28445457)
GO_REF:0000024		 RGD
UniProt		 PMID:24067497 PMID:28445457 GO_REF:0000024 MGI:5902676 MGI:5902863 NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        monoatomic ion transmembrane transporter activity 752
          active monoatomic ion transmembrane transporter activity 257
            metal cation:monoatomic cation antiporter activity 41
              calcium:monoatomic cation antiporter activity 12
                calcium:manganese antiporter activity 1
                calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration 3
                calcium:monoatomic cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration 0
                calcium:proton antiporter activity 2
                calcium:sodium antiporter activity + 9
Path 2
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        monoatomic ion transmembrane transporter activity 752
          monoatomic cation transmembrane transporter activity 631
            metal ion transmembrane transporter activity 461
              metal cation:monoatomic cation antiporter activity 41
                calcium:monoatomic cation antiporter activity 12
                  calcium:manganese antiporter activity 1
                  calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration 3
                  calcium:monoatomic cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration 0
                  calcium:proton antiporter activity 2
                  calcium:sodium antiporter activity + 9
paths to the root