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ONTOLOGY REPORT - ANNOTATIONS


Term:glycerol channel activity
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Accession:GO:0015254 term browser browse the term
Definition:Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
Synonyms:xref: MetaCyc:TRANS-RXN-131;   RHEA:29675;   reactome:R-HSA-432049 "Aquaporin-9 passively transports glycerol into cell";   reactome:R-HSA-432074 "Aquaporin-7 passively transports glycerol out of cell";   reactome:R-HSA-507869 "Aquaporins passively transport glycerol into cells";   reactome:R-HSA-507871 "Aquaporins passively transport glycerol out of cells"



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glycerol channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp10 aquaporin 10 enables ISO (PMID:30420639) RGD PMID:30420639 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815
JBrowse link
G Aqp11 aquaporin 11 enables ISO
ISS
IEA
(PMID:24845055)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:24845055 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:152,046,515...152,056,675
Ensembl chr 1:152,046,517...152,056,725
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) enables IEA
ISO
IDA
IBA
GO_REF:0000107
(PMID:17943189), (PMID:30420639)
PMID:7517548
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:17943189 PMID:30420639 PMID:7517548 GO_REF:0000033 GO_REF:0000107, RGD:68717 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Aqp7 aquaporin 7 enables IDA
ISO
IBA
(PMID:11952783), (PMID:30420639), (PMID:9405233)
GO_REF:0000033
RGD
GO_Central
PMID:9405233 PMID:11952783 PMID:30420639 PMID:9252401 GO_REF:0000033, RGD:69753 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Aqp9 aquaporin 9 enables ISO
ISS
IBA
(PMID:10564231), (PMID:18762715), (PMID:30420639)
GO_REF:0000024
GO_REF:0000033
RGD
UniProt
GO_Central
PMID:10564231 PMID:18762715 PMID:30420639 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20893
    transporter activity 1260
      transmembrane transporter activity 1153
        carbohydrate transmembrane transporter activity 44
          glycerol transmembrane transporter activity 7
            glycerol channel activity 5
Path 2
Term Annotations click to browse term
  molecular_function 20893
    transporter activity 1260
      transmembrane transporter activity 1153
        organic hydroxy compound transmembrane transporter activity 52
          polyol transmembrane transporter activity 10
            glycerol transmembrane transporter activity 7
              glycerol channel activity 5
paths to the root