ONTOLOGY REPORT - ANNOTATIONS


Term:metalloendopeptidase inhibitor activity
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Accession:GO:0008191 term browser browse the term
Definition:Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
Synonyms:broad_synonym: metalloprotease inhibitor;   metalloproteinase inhibitor


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metalloendopeptidase inhibitor activity term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G BST2 bone marrow stromal cell antigen 2 GBrowse link IDA 19 17,513,755 17,516,384 RGD:2290271 UniProtKB
G COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) GBrowse link NAS 2 228,029,281 228,179,508 RGD:2290271 UniProtKB
G LXN latexin GBrowse link IEA 3 158,384,203 158,390,482 RGD:2290271 ENSEMBL
G RECK reversion-inducing-cysteine-rich protein with kazal motifs GBrowse link TAS 9 36,036,910 36,124,452 RGD:2290271 PINC
G SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 GBrowse link IDA 5 136,310,987 136,835,018 RGD:2290271 UniProtKB
G SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 GBrowse link IDA 4 167,654,535 168,155,741 RGD:2290271 UniProtKB
G SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 GBrowse link IEA 4 167,654,535 168,155,741 RGD:2290271 UniProtKB
G TIMP1 TIMP metallopeptidase inhibitor 1 GBrowse link IDA X 47,441,690 47,446,190 RGD:2290271 UniProtKB
G TIMP1 TIMP metallopeptidase inhibitor 1 GBrowse link IEA X 47,441,690 47,446,190 RGD:2290271 InterPro
G TIMP2 TIMP metallopeptidase inhibitor 2 GBrowse link IEA 17 76,849,059 76,921,472 RGD:2290271 InterPro
G TIMP2 TIMP metallopeptidase inhibitor 2 GBrowse link IEA 17 76,849,059 76,921,472 RGD:2290271 ENSEMBL
G TIMP3 TIMP metallopeptidase inhibitor 3 GBrowse link TAS 22 33,196,802 33,259,028 RGD:2290271 BHF-UCL
G TIMP4 TIMP metallopeptidase inhibitor 4 GBrowse link NAS 3 12,194,568 12,200,851 RGD:2290271 UniProtKB
G WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 GBrowse link IEA 16 681,012 684,116 RGD:2290271 UniProtKB
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 GBrowse link IEA 17 48,912,605 48,919,709 RGD:2290271 UniProtKB

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 78551
    enzyme regulator activity 1559
      enzyme inhibitor activity 495
        metalloenzyme inhibitor activity 15
          metalloendopeptidase inhibitor activity 15
Path 2
Term Annotations click to browse term
  molecular_function 78551
    enzyme regulator activity 1559
      enzyme inhibitor activity 495
        peptidase inhibitor activity 288
          endopeptidase inhibitor activity 276
            metalloendopeptidase inhibitor activity 15
paths to the root