ONTOLOGY REPORT - ANNOTATIONS

Term:acrosome reaction
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Accession:GO:0007340 term browser browse the term
Definition:The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg.
Synonyms:xref_analog: Wikipedia:Acrosome_reaction

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acrosome reaction term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Acr acrosin GBrowse link ISO 7 127,885,399 127,891,552 RGD:1624291 RGD
G Acr acrosin GBrowse link ISS 7 127,885,399 127,891,552 RGD:1600115 UniProtKB
G Acr acrosin GBrowse link TAS 7 127,885,399 127,891,552 HGNC
G Glra1 glycine receptor, alpha 1 GBrowse link ISO 10 40,922,867 41,021,767 RGD:1624291 RGD
G Glra1 glycine receptor, alpha 1 GBrowse link IEA 10 40,922,867 41,021,767 RGD:1600115 ENSEMBL
G Glrb glycine receptor, beta GBrowse link ISO 2 172,451,807 172,522,841 RGD:1624291 RGD
G Glrb glycine receptor, beta GBrowse link IEA 2 172,451,807 172,522,841 RGD:1600115 ENSEMBL
G Pcsk4 proprotein convertase subtilisin/kexin type 4 GBrowse link ISO 7 10,892,705 10,900,928 RGD:1624291 RGD
G Pcsk4 proprotein convertase subtilisin/kexin type 4 GBrowse link IEA 7 10,892,705 10,900,928 RGD:1600115 ENSEMBL
G Plcd4 phospholipase C, delta 4 GBrowse link ISO 9 73,878,506 73,905,127 RGD:1624291 RGD
G Plcd4 phospholipase C, delta 4 GBrowse link IEA 9 73,878,506 73,905,127 RGD:1600115 ENSEMBL
G Spesp1 sperm equatorial segment protein 1 GBrowse link IEA 8 66,408,588 66,423,084 RGD:1600115 ENSEMBL
G Spesp1 sperm equatorial segment protein 1 GBrowse link ISO 8 66,408,588 66,423,084 RGD:1624291 RGD
G Stx2 syntaxin 2 GBrowse link ISO 12 28,751,591 28,773,351 RGD:1624291 RGD
G Syt6 synaptotagmin VI GBrowse link ISO 2 198,807,340 198,862,227 RGD:1624291 RGD
G Syt8 synaptotagmin VIII GBrowse link ISO 1 202,683,924 202,686,122 RGD:1624291 RGD
G Tnp2 transition protein 2 GBrowse link IEA 10 4,816,612 4,817,340 RGD:1600115 ENSEMBL
G Tnp2 transition protein 2 GBrowse link ISO 10 4,816,612 4,817,340 RGD:1624291 RGD
G Trim36 tripartite motif-containing 36 GBrowse link ISO 18 40,329,191 40,356,113 RGD:1624291 RGD
G Trim36 tripartite motif-containing 36 GBrowse link IEA 18 40,329,191 40,356,113 RGD:1600115 ENSEMBL
G Trpc2 transient receptor potential cation channel, subfamily C, member 2 GBrowse link ISO 1 159,542,801 159,576,294 RGD:1624291 RGD
acrosomal vesicle exocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Eqtn equatorin, sperm acrosome associated GBrowse link ISO 5 115,214,513 115,224,207 RGD:1624291 RGD
G Syt6 synaptotagmin VI GBrowse link ISO 2 198,807,340 198,862,227 RGD:1624291 RGD
G Zp4 zona pellucida glycoprotein 4 GBrowse link IEA 17 69,576,957 69,583,510 RGD:1600115 ENSEMBL
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISS 12 21,805,746 21,812,711 RGD:1600115 UniProtKB
positive regulation of acrosome reaction term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit GBrowse link ISO 10 14,621,372 14,679,051 RGD:1624291 RGD
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit GBrowse link IEA 10 14,621,372 14,679,051 RGD:1600115 ENSEMBL
G Glra1 glycine receptor, alpha 1 GBrowse link ISO 10 40,922,867 41,021,767 RGD:1624291 RGD
G Glra1 glycine receptor, alpha 1 GBrowse link IEA 10 40,922,867 41,021,767 RGD:1600115 ENSEMBL
G Plcb1 phospholipase C, beta 1 (phosphoinositide-specific) GBrowse link ISO 3 122,797,718 123,523,675 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link IEA 12 21,805,746 21,812,711 RGD:1600115 ENSEMBL
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISO 12 21,805,746 21,812,711 RGD:1624291 RGD
G Zp3 zona pellucida glycoprotein 3 (sperm receptor) GBrowse link ISS 12 21,805,746 21,812,711 RGD:1600115 UniProtKB
G Zp4 zona pellucida glycoprotein 4 GBrowse link IEA 17 69,576,957 69,583,510 RGD:1600115 ENSEMBL
regulation of acrosome reaction term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 GBrowse link ISO 5 58,196,388 58,243,231 RGD:1624291 RGD
G B4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 GBrowse link IEA 5 58,196,388 58,243,231 RGD:1600115 ENSEMBL
G Pkdrej polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) GBrowse link IEA 7 123,820,836 123,827,210 RGD:1600115 ENSEMBL
G Pkdrej polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) GBrowse link ISO 7 123,820,836 123,827,210 RGD:1624291 RGD
G Serpina10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 GBrowse link NOT ISO 6 127,887,684 127,896,122 RGD:1624291 RGD
G Spink1 serine peptidase inhibitor, Kazal type 1 GBrowse link ISO 18 37,090,934 37,099,835 RGD:1624291 RGD
G Zp2 zona pellucida glycoprotein 2 (sperm receptor) NOT ISO RGD:1624291 RGD
G Zp2 zona pellucida glycoprotein 2 (sperm receptor) NOT ISO RGD:1624291 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 136531
    cellular process 85606
      cellular process involved in reproduction 1117
        acrosome reaction 47
          acrosomal vesicle exocytosis + 6
          acrosome matrix dispersal 0
          membrane fusion involved in acrosome reaction 0
          peptidyl-serine phosphorylation involved in acrosome reaction 0
          positive regulation of acrosome reaction 12
          positive regulation of actin filament polymerization involved in acrosome reaction 0
          protein localization involved in acrosome reaction 0
          regulation of acrosome reaction + 23
Path 2
Term Annotations click to browse term
  biological_process 136531
    localization 13374
      establishment of localization 9639
        transport 9442
          single-organism transport 8060
            secretion 1903
              secretion by cell 1579
                exocytosis 448
                  calcium ion-dependent exocytosis 115
                    acrosome reaction 47
                      acrosomal vesicle exocytosis + 6
                      acrosome matrix dispersal 0
                      membrane fusion involved in acrosome reaction 0
                      peptidyl-serine phosphorylation involved in acrosome reaction 0
                      positive regulation of acrosome reaction 12
                      positive regulation of actin filament polymerization involved in acrosome reaction 0
                      protein localization involved in acrosome reaction 0
                      regulation of acrosome reaction + 23
paths to the root

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