ONTOLOGY REPORT - ANNOTATIONS


Term:cell cycle arrest
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Accession:GO:0007050 term browser browse the term
Definition:A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
Synonyms:exact_synonym: arrest of cell cycle progression;   cessation of cell cycle;   termination of cell cycle
 xref_analog: Reactome:REACT_104854;   Reactome:REACT_110745;   Reactome:REACT_21387;   Reactome:REACT_34173;   Reactome:REACT_34536;   Reactome:REACT_78416;   Reactome:REACT_78593;   Reactome:REACT_79397;   Reactome:REACT_80257;   Reactome:REACT_80760;   Reactome:REACT_81821;   Reactome:REACT_84630;   Reactome:REACT_86872;   Reactome:REACT_90070;   Reactome:REACT_90301;   Reactome:REACT_92874;   Reactome:REACT_92909


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cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ak1 adenylate kinase 1 JBrowse link 3 11,652,143 11,659,135 RGD:1600115
RGD:1624291
G Apbb1 amyloid beta precursor protein binding family B member 1 JBrowse link 1 170,387,625 170,411,263 RGD:1600115
RGD:1624291
G Apbb2 amyloid beta precursor protein binding family B member 2 JBrowse link 14 43,205,047 43,526,968 RGD:1624291
G Apc APC, WNT signaling pathway regulator JBrowse link 18 27,011,710 27,106,323 RGD:1600115
RGD:1624291
G Atm ATM serine/threonine kinase JBrowse link 8 58,015,938 58,119,973 RGD:1600115
RGD:1624291
G Brinp1 BMP/retinoic acid inducible neural specific 1 JBrowse link 5 84,919,416 85,123,828 RGD:1600115
G Brinp2 BMP/retinoic acid inducible neural specific 2 JBrowse link 13 75,948,679 76,049,363 RGD:1600115
G Brinp3 BMP/retinoic acid inducible neural specific 3 JBrowse link 13 63,526,486 63,959,390 RGD:1600115
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:1600115
RGD:1624291
G Cdc123 cell division cycle 123 JBrowse link 17 76,410,629 76,454,275 RGD:1600115
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:1600115
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1600115
RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:1600115
RGD:1624291
G Cdkn2c cyclin-dependent kinase inhibitor 2C JBrowse link 5 129,347,731 129,352,886 RGD:1600115
RGD:1624291
G Cdkn3 cyclin-dependent kinase inhibitor 3 JBrowse link 15 23,553,171 23,564,538 RGD:1600115
RGD:1624291
G Cgref1 cell growth regulator with EF hand domain 1 JBrowse link 6 26,797,126 26,809,132 RGD:1600115
G Cgrrf1 cell growth regulator with ring finger domain 1 JBrowse link 15 23,619,176 23,639,622 RGD:1600115
G Commd5 COMM domain containing 5 JBrowse link 7 117,963,213 117,965,010 RGD:632845
G Ddit3 DNA-damage inducible transcript 3 JBrowse link 7 70,578,564 70,585,074 RGD:1600115
RGD:1624291
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 JBrowse link 3 110,159,624 110,245,382 RGD:1600115
G Ern1 endoplasmic reticulum to nucleus signaling 1 JBrowse link 10 94,588,555 94,682,072 RGD:1600115
RGD:1624291
G Ern2 endoplasmic reticulum to nucleus signaling 2 JBrowse link 1 192,126,023 192,142,865 RGD:1600115
RGD:1624291
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:1600115
G Gas2l1 growth arrest-specific 2 like 1 JBrowse link 14 85,308,443 85,318,475 RGD:1600115
G Hras Harvey rat sarcoma virus oncogene JBrowse link 1 214,178,404 214,181,841 RGD:1600115
RGD:1624291
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:1600115
RGD:1624291
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:1600115
RGD:1624291
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:1600115
RGD:1624291
G Ilk integrin-linked kinase JBrowse link 1 170,578,941 170,585,192 RGD:2301768
G Ing4 inhibitor of growth family, member 4 JBrowse link 4 157,554,729 157,563,353 RGD:1600115
RGD:1624291
G Inhba inhibin beta A subunit JBrowse link 17 51,894,869 51,919,998 RGD:1600115
RGD:1624291
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:1600115
RGD:1624291
G Irf6 interferon regulatory factor 6 JBrowse link 13 111,870,121 111,889,328 RGD:1600115
RGD:1624291
G Jmy junction mediating and regulatory protein, p53 cofactor JBrowse link 2 23,026,506 23,097,702 RGD:1624291
G LOC100910954 cellular tumor antigen p53-like JBrowse link 2 49,338,328 49,383,164 RGD:1600115
G LOC102551694 killin-like JBrowse link 1 251,417,849 251,420,794 RGD:1624291
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:1600115
RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1624291
G Mfn2 mitofusin 2 JBrowse link 5 164,684,244 164,715,414 RGD:1304351
G Mlf1 myeloid leukemia factor 1 JBrowse link 2 164,549,423 164,582,645 RGD:1600115
RGD:1624291
G Msh2 mutS homolog 2 JBrowse link 6 11,215,951 11,274,916 RGD:1600115
RGD:1624291
G Myc myelocytomatosis oncogene JBrowse link 7 102,586,313 102,591,240 RGD:1624291
G Notch2 notch 2 JBrowse link 2 200,187,184 200,320,403 RGD:1600115
RGD:1624291
G Pkd1 polycystic kidney disease 1 JBrowse link 10 13,914,057 13,962,008 RGD:1600115
RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1600115
RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1600115
RGD:1624291
G Pmp22 peripheral myelin protein 22 JBrowse link 10 49,538,588 49,568,583 RGD:1600115
G Ppm1g protein phosphatase, Mg2+/Mn2+ dependent, 1G JBrowse link 6 26,517,840 26,537,292 RGD:1600115
RGD:1624291
G Rassf1 Ras association domain family member 1 JBrowse link 8 116,307,149 116,318,289 RGD:1600115
RGD:1624291
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:1600115
RGD:1624291
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1624291
G Rprm reprimo, TP53 dependent G2 arrest mediator candidate JBrowse link 3 39,595,301 39,596,718 RGD:1600115
RGD:1624291
G Sgsm3 small G protein signaling modulator 3 JBrowse link 7 122,203,498 122,232,993 RGD:1600115
G Skil SKI-like proto-oncogene JBrowse link 2 115,862,932 115,891,304 RGD:1600115
RGD:1624291
G Slfn2 schlafen 2 JBrowse link 10 70,370,381 70,376,718 RGD:1624291
G Smad3 SMAD family member 3 JBrowse link 8 68,569,530 68,678,349 RGD:1600115
RGD:1624291
G Sox2 SRY box 2 JBrowse link 2 121,165,137 121,167,545 RGD:1600115
RGD:1624291
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:1600115
RGD:1624291
G Tbrg1 transforming growth factor beta regulator 1 JBrowse link 8 40,114,792 40,122,450 RGD:1624291
G Tcf7l2 transcription factor 7 like 2 JBrowse link 1 276,686,911 276,730,517 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1600115
RGD:1624291
G Tgfb2 transforming growth factor, beta 2 JBrowse link 13 105,039,639 105,142,010 RGD:1600115
RGD:1624291
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:1600115
RGD:1624291
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1600115
RGD:1624291
G Tsg101 tumor susceptibility 101 JBrowse link 1 102,941,151 102,971,017 RGD:1600115
RGD:1624291
G Uhmk1 U2AF homology motif kinase 1 JBrowse link 13 88,521,625 88,536,728 RGD:1624291
G Wdr6 WD repeat domain 6 JBrowse link 8 117,358,345 117,364,761 RGD:1624291
G Wnt10b wingless-type MMTV integration site family, member 10B JBrowse link 7 140,448,284 140,466,159 RGD:1600115
RGD:1624291
G Zak sterile alpha motif and leucine zipper containing kinase AZK JBrowse link 3 58,965,025 59,120,507 RGD:1600115
RGD:1624291
G Zbtb49 zinc finger and BTB domain containing 49 JBrowse link 14 77,322,014 77,343,736 RGD:1600115
RGD:1624291
G Zfhx3 zinc finger homeobox 3 JBrowse link 19 42,753,983 42,925,794 RGD:1625359
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp2 caspase 2 JBrowse link 4 71,652,358 71,670,228 RGD:1600115
RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1600115
RGD:1624291
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain JBrowse link 7 36,395,665 36,408,588 RGD:1600115
RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1600115
RGD:1624291
G Muc1 mucin 1, cell surface associated JBrowse link 2 188,543,137 188,547,874 RGD:1624291
G Pidd1 p53-induced death domain protein 1 JBrowse link 1 214,418,751 214,423,959 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1600115
RGD:1624291
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma JBrowse link 6 134,804,128 134,941,912 RGD:1624291
G Rbm38 RNA binding motif protein 38 JBrowse link 3 171,037,891 171,050,500 RGD:1624291
G Sox4 SRY box 4 JBrowse link 17 37,615,022 37,619,728 RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
mitotic cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1600115
RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1600115
RGD:1624291
G Ddias DNA damage-induced apoptosis suppressor JBrowse link 1 157,675,754 157,700,064 RGD:1624291
G Dusp1 dual specificity phosphatase 1 JBrowse link 10 16,970,642 16,973,425 RGD:1600115
G Fap fibroblast activation protein, alpha JBrowse link 3 48,467,781 48,536,242 RGD:1600115
RGD:1624291
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:1600115
RGD:1624291
G Gadd45gip1 GADD45G interacting protein 1 JBrowse link 19 25,946,979 25,949,528 RGD:1600115
RGD:1624291
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:8553803
G Mcph1 microcephalin 1 JBrowse link 16 75,904,087 76,110,624 RGD:1624291
G Nkx3-1 NK3 homeobox 1 JBrowse link 15 51,065,316 51,067,908 RGD:1600115
RGD:1624291
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 JBrowse link 14 113,530,470 113,561,645 RGD:1600115
RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
negative regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cast calpastatin JBrowse link 2 1,452,111 1,561,669 RGD:5683637
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1600115
RGD:1624291
G Ccnk cyclin K JBrowse link 6 132,090,235 132,113,560 RGD:1600115
RGD:1624291
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:1600115
RGD:1624291
G Cdk9 cyclin-dependent kinase 9 JBrowse link 3 11,742,269 11,747,117 RGD:1600115
RGD:1624291
G Chek2 checkpoint kinase 2 JBrowse link 12 51,845,574 51,878,098 RGD:633752
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1600115
RGD:1624291
G Foxe3 forkhead box E3 JBrowse link 5 133,724,796 133,725,656 RGD:1624291
RGD:2290270
RGD:10047255
G Gper1 G protein-coupled estrogen receptor 1 JBrowse link 12 17,309,122 17,315,267 RGD:1600115
RGD:1624291
G Hmgn5 high mobility group nucleosome binding domain 5 JBrowse link X 80,134,557 80,142,902 RGD:1624291
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:1600115
RGD:1624291
G Mdm4 MDM4, p53 regulator JBrowse link 13 49,786,776 49,828,780 RGD:1600115
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) JBrowse link 20 13,715,219 13,732,980 RGD:1624291
G Mlxipl MLX interacting protein-like JBrowse link 12 24,590,645 24,619,639 RGD:1624291
G Nupr2 nuclear protein 2, transcriptional regulator JBrowse link 12 30,300,936 30,304,041 RGD:1600115
RGD:1624291
G Rassf1 Ras association domain family member 1 JBrowse link 8 116,307,149 116,318,289 RGD:1624291
G Setmar SET domain and mariner transposase fusion gene JBrowse link 4 140,092,346 140,104,495 RGD:1600115
RGD:1624291
G Tfap4 transcription factor AP-4 JBrowse link 10 11,204,616 11,222,975 RGD:1600115
RGD:1624291
positive regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:1600115
RGD:1624291
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:1600115
RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Crlf3 cytokine receptor-like factor 3 JBrowse link 10 67,383,664 67,401,836 RGD:1624291
G Dab2ip DAB2 interacting protein JBrowse link 3 14,889,263 15,060,286 RGD:1600115
RGD:1624291
G Fap fibroblast activation protein, alpha JBrowse link 3 48,467,781 48,536,242 RGD:1600115
RGD:1624291
G Foxo4 forkhead box O4 JBrowse link X 71,155,284 71,162,158 RGD:1600115
RGD:1624291
G Gata6 GATA binding protein 6 JBrowse link 18 2,415,821 2,447,087 RGD:1600115
RGD:1624291
G Hmga2 high mobility group AT-hook 2 JBrowse link 7 65,159,944 65,275,408 RGD:1600115
RGD:1624291
G Id2 inhibitor of DNA binding 2, HLH protein JBrowse link 6 44,360,077 44,361,908 RGD:1600115
RGD:1624291
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:1624291
G LOC100910954 cellular tumor antigen p53-like JBrowse link 2 49,338,328 49,383,164 RGD:1600115
G Med25 mediator complex subunit 25 JBrowse link 1 100,872,240 100,887,864 RGD:1600115
RGD:1624291
G Mybbp1a MYB binding protein 1a JBrowse link 10 59,000,400 59,010,794 RGD:1600115
RGD:1624291
G Myog myogenin JBrowse link 13 51,126,459 51,129,048 RGD:1600115
RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1600115
RGD:1624291
G Pou4f1 POU class 4 homeobox 1 JBrowse link 15 88,618,255 88,622,712 RGD:1600115
RGD:1624291
G Ppp2r5b protein phosphatase 2, regulatory subunit B', beta JBrowse link 1 221,597,294 221,605,467 RGD:8553977
G Prkaca protein kinase cAMP-activated catalytic subunit alpha JBrowse link 19 25,095,089 25,118,869 RGD:1600115
RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1600115
RGD:1624291
G Rnf112 ring finger protein 112 JBrowse link 10 47,719,034 47,726,050 RGD:1600115
RGD:1624291
G Rrp8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) JBrowse link 1 170,574,670 170,578,693 RGD:1600115
RGD:1624291
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:1600115
RGD:1624291
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:1624291
G Tp73 tumor protein p73 JBrowse link 5 171,355,876 171,415,354 RGD:1600115
RGD:1624291
G Uhrf2 ubiquitin like with PHD and ring finger domains 2 JBrowse link 1 248,228,496 248,291,984 RGD:1600115
RGD:1624291
regulation of cell cycle arrest term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291
G Foxm1 forkhead box M1 JBrowse link 4 161,685,236 161,697,633 RGD:1600115
RGD:1624291
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1600115
RGD:1624291
G Slc25a33 solute carrier family 25 member 33 JBrowse link 5 166,701,463 166,726,794 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 502888
    cellular process 315656
      cell cycle process 8128
        cell cycle arrest 712
          G1 cell cycle arrest in response to nitrogen starvation + 0
          cell cycle arrest of committed forebrain neuronal progenitor cell 0
          mitotic cell cycle arrest + 47
          negative regulation of cell cycle arrest 68
          positive regulation of cell cycle arrest + 191
          regulation of cell cycle arrest + 278
Path 2
Term Annotations click to browse term
  biological_process 502888
    cellular process 315656
      single-organism cellular process 185291
        cell cycle 9868
          regulation of cell cycle 4713
            negative regulation of cell cycle 1995
              cell cycle arrest 712
                G1 cell cycle arrest in response to nitrogen starvation + 0
                cell cycle arrest of committed forebrain neuronal progenitor cell 0
                mitotic cell cycle arrest + 47
                negative regulation of cell cycle arrest 68
                positive regulation of cell cycle arrest + 191
                regulation of cell cycle arrest + 278
paths to the root