ONTOLOGY REPORT - ANNOTATIONS


Term:ER overload response
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Accession:GO:0006983 term browser browse the term
Definition:The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.
Synonyms:exact_synonym: EOR;   endoplasmic reticulum overload response


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ER overload response term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ccdc47 coiled-coil domain containing 47 GBrowse link ISO 10 95,593,531 95,612,057 RGD:1624291 RGD
G Ccdc47 coiled-coil domain containing 47 GBrowse link IEA 10 95,593,531 95,612,057 RGD:1600115 ENSEMBL
G Ddit3 DNA-damage inducible transcript 3 GBrowse link IMP 7 67,247,749 67,252,571 RGD:70575 RGD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link ISO 7 67,247,749 67,252,571 RGD:1624291 RGD
G Ddit3 DNA-damage inducible transcript 3 GBrowse link IEA 7 67,247,749 67,252,571 RGD:1600115 ENSEMBL
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISO 4 104,016,940 104,078,261 RGD:1624291 RGD
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISO 4 104,016,940 104,078,261 RGD:1624291 RGD
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 GBrowse link ISS 4 104,016,940 104,078,261 RGD:1600115 UniProtKB
G Gsk3b glycogen synthase kinase 3 beta GBrowse link ISO 11 64,284,731 64,428,698 RGD:1624291 RGD
G Gsk3b glycogen synthase kinase 3 beta GBrowse link ISO 11 64,284,731 64,428,698 RGD:1624291 RGD
G Gsk3b glycogen synthase kinase 3 beta GBrowse link IEA 11 64,284,731 64,428,698 RGD:1600115 ENSEMBL
G Gsk3b glycogen synthase kinase 3 beta GBrowse link IEA 11 64,284,731 64,428,698 RGD:1600115 ENSEMBL
G Hspa5 heat shock protein 5 GBrowse link ISO 3 13,783,825 13,788,022 RGD:1624291 RGD
G Hspa5 heat shock protein 5 GBrowse link IEA 3 13,783,825 13,788,022 RGD:1600115 ENSEMBL
G Ins2 insulin 2 GBrowse link ISO 1 202,935,548 202,936,379 RGD:1624291 RGD
G Ins2 insulin 2 GBrowse link IEA 1 202,935,548 202,936,379 RGD:1600115 ENSEMBL
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B GBrowse link ISO 13 46,039,831 46,047,636 RGD:1624291 RGD
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B GBrowse link IEA 13 46,039,831 46,047,636 RGD:1600115 ENSEMBL
G Tp53 tumor protein p53 GBrowse link ISO 10 56,399,721 56,411,150 RGD:1624291 RGD
G Vimp VCP-interacting membrane protein GBrowse link ISO 1 120,509,100 120,518,867 RGD:1624291 RGD
G Vimp VCP-interacting membrane protein GBrowse link ISO 1 120,509,100 120,518,867 RGD:1624291 RGD
G Vimp VCP-interacting membrane protein GBrowse link IEA 1 120,509,100 120,518,867 RGD:1600115 ENSEMBL
autophagy in response to ER overload term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Atg10 autophagy related 10 GBrowse link IEA 2 21,076,289 21,374,627 RGD:1600115 ENSEMBL
G Atg10 autophagy related 10 GBrowse link ISO 2 21,076,289 21,374,627 RGD:1624291 RGD

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    response to stimulus 34057
      response to biotic stimulus 1534
        cellular response to biotic stimulus 287
          ER overload response 24
            autophagy in response to ER overload 2
            detection of endoplasmic reticulum overloading 0
            positive regulation of NF-kappaB transcription factor activity by ER overload response 0
Path 2
Term Annotations click to browse term
  biological_process 135967
    cellular process 85138
      single-organism cellular process 56334
        cell communication 16469
          signal transduction 13563
            ER-nucleus signaling pathway 106
              ER overload response 24
                autophagy in response to ER overload 2
                detection of endoplasmic reticulum overloading 0
                positive regulation of NF-kappaB transcription factor activity by ER overload response 0
paths to the root