ONTOLOGY REPORT - ANNOTATIONS
Term: muscle contraction
Accession: GO:0006936
browse the term
Definition: A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
Synonyms: xref_analog: Reactome:REACT_100109; Reactome:REACT_102067; Reactome:REACT_20558; Reactome:REACT_29015; Reactome:REACT_77478; Reactome:REACT_81255; Reactome:REACT_83607; Reactome:REACT_85440; Reactome:REACT_87764; Reactome:REACT_88232; Reactome:REACT_92442; Wikipedia:Muscle_contraction
muscle contraction
G
ACTA1
actin, alpha 1, skeletal muscle
TAS
1
229,566,992
229,569,843
RGD:2290271
UniProtKB
G
ACTA2
actin, alpha 2, smooth muscle, aorta
TAS
10
90,694,831
90,751,147
RGD:2290271
Reactome
G
ACTG2
actin, gamma 2, smooth muscle, enteric
TAS
2
74,120,093
74,146,780
RGD:2290271
Reactome
G
ACTN2
actinin, alpha 2
IEA
1
236,849,770
236,927,558
RGD:2290271
ENSEMBL
G
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
NAS
10
99,332,256
99,343,641
RGD:2290271
UniProtKB
G
ASPH
aspartate beta-hydroxylase
TAS
8
62,413,115
62,627,199
RGD:2290271
PINC
G
CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
TAS
16
1,203,241
1,271,772
RGD:2290271
PINC
G
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
IMP
1
201,008,640
201,081,694
RGD:2290271
UniProtKB
G
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
TAS
17
65,040,652
65,052,913
RGD:2290271
PINC
G
CALD1
caldesmon 1
IEA
7
134,464,164
134,655,480
RGD:2290271
InterPro
G
CALD1
caldesmon 1
TAS
7
134,464,164
134,655,480
RGD:2290271
Reactome
G
CALM1
calmodulin 1 (phosphorylase kinase, delta)
TAS
14
90,863,327
90,874,619
RGD:2290271
Reactome
G
CALM2
calmodulin 2 (phosphorylase kinase, delta)
TAS
2
47,387,221
47,403,740
RGD:2290271
Reactome
G
CALM3
calmodulin 3 (phosphorylase kinase, delta)
TAS
19
47,104,512
47,114,039
RGD:2290271
Reactome
G
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
IMP
17
7,348,406
7,360,932
RGD:2290271
UniProtKB
G
CHRND
cholinergic receptor, nicotinic, delta (muscle)
TAS
2
233,390,870
233,401,375
RGD:2290271
PINC
G
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
TAS
17
4,801,064
4,806,369
RGD:2290271
PINC
G
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
TAS
2
233,404,437
233,411,038
RGD:2290271
PINC
G
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
TAS
5
80,529,139
80,562,217
RGD:2290271
PINC
G
CLCN1
chloride channel, voltage-sensitive 1
TAS
7
143,013,219
143,049,097
RGD:2290271
PINC
G
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
IEA
5
74,666,928
74,807,806
RGD:2290271
ENSEMBL
G
CRYAB
crystallin, alpha B
TAS
11
111,779,350
111,782,473
RGD:2290271
PINC
G
DES
desmin
TAS
2
220,283,099
220,291,461
RGD:2290271
PINC
G
EMD
emerin
TAS
X
153,607,597
153,609,883
RGD:2290271
PINC
G
FKBP1B
FK506 binding protein 1B, 12.6 kDa
NAS
2
24,272,584
24,286,551
RGD:2290271
UniProtKB
G
FLII
flightless I homolog (Drosophila)
TAS
17
18,148,129
18,162,230
RGD:2290271
PINC
G
FXYD1
FXYD domain containing ion transport regulator 1
TAS
19
35,629,732
35,633,954
RGD:2290271
PINC
G
GALR2
galanin receptor 2
TAS
17
74,070,892
74,073,573
RGD:2290271
PINC
G
GAMT
guanidinoacetate N-methyltransferase
TAS
19
1,397,025
1,401,569
RGD:2290271
PINC
G
GJA1
gap junction protein, alpha 1, 43kDa
TAS
6
121,756,745
121,770,873
RGD:2290271
PINC
G
GJC1
gap junction protein, gamma 1, 45kDa
TAS
17
42,875,816
42,908,179
RGD:2290271
PINC
G
GLRA1
glycine receptor, alpha 1
IMP
5
151,202,074
151,304,397
RGD:2290271
UniProtKB
G
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
TAS
16
56,225,251
56,391,356
RGD:2290271
PINC
G
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
TAS
19
589,893
617,159
RGD:2290271
PINC
G
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
TAS
15
73,612,200
73,661,605
RGD:2290271
PINC
G
HRC
histidine rich calcium binding protein
TAS
19
49,654,455
49,658,681
RGD:2290271
PINC
G
HSBP1
heat shock factor binding protein 1
IEA
16
83,841,508
83,846,607
RGD:2290271
ENSEMBL
G
ITGA1
integrin, alpha 1
TAS
5
52,084,136
52,249,485
RGD:2290271
Reactome
G
ITGB5
integrin, beta 5
TAS
3
124,481,795
124,606,144
RGD:2290271
Reactome
G
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
TAS
21
35,818,986
35,884,573
RGD:2290271
PINC
G
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
TAS
21
35,736,323
35,743,440
RGD:2290271
PINC
G
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
TAS
7
150,642,044
150,675,402
RGD:2290271
PINC
G
KCNIP2
Kv channel interacting protein 2
NAS
10
103,585,731
103,603,677
RGD:2290271
UniProtKB
G
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
TAS
17
21,279,699
21,323,179
RGD:2290271
PINC
G
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
TAS
11
2,466,221
2,870,340
RGD:2290271
PINC
G
LMOD1
leiomodin 1 (smooth muscle)
TAS
1
201,865,584
201,915,716
RGD:2290271
Reactome
G
LTB4R
leukotriene B4 receptor
TAS
14
24,780,705
24,787,242
RGD:2290271
PINC
G
MYBPC1
myosin binding protein C, slow type
IEA
12
101,988,709
102,079,658
RGD:2290271
ENSEMBL
G
MYH11
myosin, heavy chain 11, smooth muscle
TAS
16
15,796,992
15,950,887
RGD:2290271
Reactome
G
MYH13
myosin, heavy chain 13, skeletal muscle
TAS
17
10,204,183
10,276,322
RGD:2290271
UniProtKB
G
MYH2
myosin, heavy chain 2, skeletal muscle, adult
TAS
17
10,424,465
10,453,017
RGD:2290271
UniProtKB
G
MYH2
myosin, heavy chain 2, skeletal muscle, adult
IDA
17
10,424,465
10,453,017
RGD:2290271
BHF-UCL
G
MYH4
myosin, heavy chain 4, skeletal muscle
IDA
17
10,346,607
10,372,876
RGD:2290271
BHF-UCL
G
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
IDA
14
23,851,199
23,877,486
RGD:2290271
HGNC
G
MYH7
myosin, heavy chain 7, cardiac muscle, beta
IDA
14
23,881,947
23,903,496
RGD:2290271
HGNC
G
MYH7
myosin, heavy chain 7, cardiac muscle, beta
TAS
14
23,881,947
23,903,496
RGD:2290271
HGNC
G
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
NAS
17
10,293,642
10,325,267
RGD:2290271
UniProtKB
G
MYL1
myosin, light chain 1, alkali; skeletal, fast
IDA
2
211,154,868
211,179,895
RGD:2290271
BHF-UCL
G
MYL12B
myosin, light chain 12B, regulatory
TAS
18
3,262,111
3,278,282
RGD:2290271
Reactome
G
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
TAS
12
56,552,045
56,555,366
RGD:2290271
HGNC
G
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
TAS
12
56,552,045
56,555,366
RGD:2290271
Reactome
G
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
TAS
12
56,546,204
56,551,771
RGD:2290271
HGNC
G
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
TAS
12
56,546,204
56,551,771
RGD:2290271
Reactome
G
MYL9
myosin, light chain 9, regulatory
TAS
20
35,169,887
35,178,226
RGD:2290271
Reactome
G
MYLK
myosin light chain kinase
TAS
3
123,331,143
123,603,149
RGD:2290271
Reactome
G
MYOF
myoferlin
TAS
10
95,066,186
95,242,074
RGD:2290271
PINC
G
MYOM1
myomesin 1
IEA
18
3,066,805
3,220,106
RGD:2290271
ENSEMBL
G
MYOM2
myomesin 2
IEA
8
1,993,158
2,093,380
RGD:2290271
ENSEMBL
G
MYOT
myotilin
TAS
5
137,203,545
137,223,540
RGD:2290271
PINC
G
OXTR
oxytocin receptor
TAS
3
8,792,094
8,811,300
RGD:2290271
PINC
G
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
TAS
22
21,369,442
21,382,302
RGD:2290271
PINC
G
PABPN1
poly(A) binding protein, nuclear 1
TAS
14
23,789,397
23,795,394
RGD:2290271
PINC
G
PXN
paxillin
TAS
12
120,648,242
120,703,574
RGD:2290271
Reactome
G
RYR1
ryanodine receptor 1 (skeletal)
ISS
19
38,924,340
39,078,204
RGD:2290271
UniProtKB
G
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
TAS
17
62,015,914
62,050,278
RGD:2290271
PINC
G
SCN7A
sodium channel, voltage-gated, type VII, alpha subunit
TAS
2
167,260,083
167,343,481
RGD:2290271
PINC
G
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
TAS
17
48,243,366
48,253,293
RGD:2290271
PINC
G
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
TAS
X
152,953,752
152,962,048
RGD:2290271
PINC
G
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
TAS
2
40,339,286
40,739,575
RGD:2290271
PINC
G
SLMAP
sarcolemma associated protein
TAS
3
57,743,174
57,914,894
RGD:2290271
PINC
G
SNTA1
syntrophin, alpha 1
TAS
20
31,995,763
32,031,698
RGD:2290271
PINC
G
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
TAS
8
121,547,985
121,824,309
RGD:2290271
PINC
G
SORBS1
sorbin and SH3 domain containing 1
TAS
10
97,071,530
97,321,171
RGD:2290271
Reactome
G
SORBS3
sorbin and SH3 domain containing 3
TAS
8
22,409,251
22,433,008
RGD:2290271
Reactome
G
SSPN
sarcospan
TAS
12
26,348,269
26,387,710
RGD:2290271
PINC
G
STBD1
starch binding domain 1
TAS
4
77,227,179
77,232,283
RGD:2290271
PINC
G
TACR2
tachykinin receptor 2
TAS
10
71,163,958
71,176,674
RGD:2290271
PINC
G
TAZ
tafazzin
IMP
X
153,639,877
153,650,065
RGD:2290271
HGNC
G
TBX20
T-box 20
IEA
7
35,242,042
35,293,711
RGD:2290271
ENSEMBL
G
TLN1
talin 1
TAS
9
35,697,334
35,732,392
RGD:2290271
Reactome
G
TMOD4
tropomodulin 4 (muscle)
TAS
1
151,142,463
151,148,547
RGD:2290271
PINC
G
TPM1
tropomyosin 1 (alpha)
TAS
15
63,334,838
63,364,114
RGD:2290271
Reactome
G
TPM2
tropomyosin 2 (beta)
TAS
9
35,681,990
35,690,053
RGD:2290271
Reactome
G
TPM3
tropomyosin 3
TAS
1
154,127,780
154,164,609
RGD:2290271
Reactome
G
TPM4
tropomyosin 4
TAS
19
16,178,317
16,213,813
RGD:2290271
Reactome
G
TRDN
triadin
TAS
6
123,537,484
123,958,238
RGD:2290271
PINC
G
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
IEA
1
26,377,795
26,394,125
RGD:2290271
ENSEMBL
G
TTN
titin
TAS
2
179,390,716
179,672,150
RGD:2290271
UniProtKB
G
TTN
titin
NAS
2
179,390,716
179,672,150
RGD:2290271
UniProtKB
G
TTN
titin
IEA
2
179,390,716
179,672,150
RGD:2290271
ENSEMBL
G
UTRN
utrophin
TAS
6
144,612,873
145,174,170
RGD:2290271
PINC
G
UTS2
urotensin 2
TAS
1
7,907,672
7,913,551
RGD:2290271
PINC
G
VCL
vinculin
TAS
10
75,757,872
75,879,918
RGD:2290271
Reactome
G
VIPR1
vasoactive intestinal peptide receptor 1
TAS
3
42,530,791
42,579,065
RGD:2290271
PINC
artery smooth muscle contraction
G
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
IEA
1
230,838,269
230,850,336
RGD:2290271
ENSEMBL
G
EDN1
endothelin 1
TAS
6
12,290,529
12,297,427
RGD:2290271
BHF-UCL
G
EDN1
endothelin 1
IDA
6
12,290,529
12,297,427
RGD:2290271
BHF-UCL
G
EDN2
endothelin 2
IDA
1
41,944,446
41,950,344
RGD:2290271
BHF-UCL
G
EDN3
endothelin 3
NOT
IDA
20
57,875,499
57,901,047
RGD:2290271
BHF-UCL
G
EDNRA
endothelin receptor type A
IMP
4
148,402,069
148,466,106
RGD:2290271
BHF-UCL
cardiac muscle cell contraction
G
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
IEA
Y
15,360,259
15,592,550
RGD:2290271
ENSEMBL
cardiac muscle contraction
G
ACTC1
actin, alpha, cardiac muscle 1
IEA
15
35,080,297
35,087,927
RGD:2290271
ENSEMBL
G
ADRBK1
adrenergic, beta, receptor kinase 1
IMP
11
67,033,905
67,054,029
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
IEA
4
113,739,239
114,304,896
RGD:2290271
ENSEMBL
G
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
IEA
4
114,372,188
114,683,083
RGD:2290271
ENSEMBL
G
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
IMP
11
19,203,577
19,232,118
RGD:2290271
BHF-UCL
G
DMD
dystrophin
IMP
X
31,137,345
33,357,726
RGD:2290271
BHF-UCL
G
GAA
glucosidase, alpha; acid
IMP
17
78,075,355
78,093,679
RGD:2290271
BHF-UCL
G
MAP2K3
mitogen-activated protein kinase kinase 3
IEA
17
21,187,968
21,218,552
RGD:2290271
ENSEMBL
G
MAP2K6
mitogen-activated protein kinase kinase 6
IEA
17
67,410,838
67,538,470
RGD:2290271
ENSEMBL
G
MYBPC3
myosin binding protein C, cardiac
ISS
11
47,352,957
47,374,253
RGD:2290271
BHF-UCL
G
MYL1
myosin, light chain 1, alkali; skeletal, fast
IEA
2
211,154,868
211,179,895
RGD:2290271
ENSEMBL
G
MYL2
myosin, light chain 2, regulatory, cardiac, slow
IEA
12
111,348,623
111,358,404
RGD:2290271
ENSEMBL
G
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
IEA
3
46,899,357
46,904,973
RGD:2290271
ENSEMBL
G
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
IMP
3
46,899,357
46,904,973
RGD:2290271
BHF-UCL
G
MYL4
myosin, light chain 4, alkali; atrial, embryonic
IMP
17
45,286,428
45,301,045
RGD:2290271
BHF-UCL
G
MYL4
myosin, light chain 4, alkali; atrial, embryonic
IMP
17
45,286,428
45,301,045
RGD:2290271
BHF-UCL
G
MYLK2
myosin light chain kinase 2
IC
20
30,407,178
30,422,500
RGD:2290271
BHF-UCL
G
MYLK2
myosin light chain kinase 2
IC
20
30,407,178
30,422,500
RGD:2290271
BHF-UCL
G
NKX2-5
NK2 homeobox 5
IEA
5
172,659,107
172,662,315
RGD:2290271
ENSEMBL
G
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
TAS
3
178,866,311
178,952,500
RGD:2290271
UniProtKB
G
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
IEA
19
45,882,892
45,909,607
RGD:2290271
ENSEMBL
G
PSEN2
presenilin 2 (Alzheimer disease 4)
IEA
1
227,058,273
227,083,804
RGD:2290271
ENSEMBL
G
RYR2
ryanodine receptor 2 (cardiac)
IMP
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
SCN1B
sodium channel, voltage-gated, type I, beta subunit
IMP
19
35,521,592
35,531,353
RGD:2290271
BHF-UCL
G
SCN2B
sodium channel, voltage-gated, type II, beta subunit
IMP
11
118,033,519
118,047,337
RGD:2290271
BHF-UCL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IMP
11
123,499,895
123,525,315
RGD:2290271
BHF-UCL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IMP
11
123,499,895
123,525,315
RGD:2290271
BHF-UCL
G
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
IMP
11
118,004,092
118,023,630
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
G
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
IEA
2
40,339,286
40,739,575
RGD:2290271
ENSEMBL
G
SMAD5
SMAD family member 5
IEA
5
135,468,536
135,518,422
RGD:2290271
ENSEMBL
G
SRSF1
serine/arginine-rich splicing factor 1
IEA
17
56,078,280
56,084,707
RGD:2290271
ENSEMBL
G
TAZ
tafazzin
IMP
X
153,639,877
153,650,065
RGD:2290271
BHF-UCL
G
TCAP
titin-cap
IMP
17
37,821,599
37,822,807
RGD:2290271
BHF-UCL
G
TCAP
titin-cap
IMP
17
37,821,599
37,822,807
RGD:2290271
BHF-UCL
G
TNNC1
troponin C type 1 (slow)
IMP
3
52,485,107
52,488,057
RGD:2290271
BHF-UCL
G
TNNI3
troponin I type 3 (cardiac)
IMP
19
55,663,135
55,669,100
RGD:2290271
UniProtKB
G
TPM1
tropomyosin 1 (alpha)
IMP
15
63,334,838
63,364,114
RGD:2290271
BHF-UCL
G
TPM1
tropomyosin 1 (alpha)
IEA
15
63,334,838
63,364,114
RGD:2290271
ENSEMBL
G
TTN
titin
IMP
2
179,390,716
179,672,150
RGD:2290271
BHF-UCL
G
VEGFB
vascular endothelial growth factor B
IEA
11
64,002,056
64,006,736
RGD:2290271
ENSEMBL
diaphragm contraction
G
GAA
glucosidase, alpha; acid
IMP
17
78,075,355
78,093,679
RGD:2290271
BHF-UCL
G
GAA
glucosidase, alpha; acid
IEA
17
78,075,355
78,093,679
RGD:2290271
ENSEMBL
esophagus smooth muscle contraction
G
SULF1
sulfatase 1
ISS
8
70,378,859
70,573,147
RGD:2290271
UniProtKB
G
SULF1
sulfatase 1
IEA
8
70,378,859
70,573,147
RGD:2290271
ENSEMBL
G
SULF2
sulfatase 2
ISS
20
46,286,150
46,415,360
RGD:2290271
UniProtKB
G
SULF2
sulfatase 2
IEA
20
46,286,150
46,415,360
RGD:2290271
ENSEMBL
intestine smooth muscle contraction
G
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IMP
1
23,518,388
23,521,222
RGD:2290271
UniProtKB
G
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IMP
2
231,972,947
231,989,824
RGD:2290271
UniProtKB
G
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IMP
2
231,972,947
231,989,824
RGD:2290271
UniProtKB
G
TACR2
tachykinin receptor 2
IEA
10
71,163,958
71,176,674
RGD:2290271
ENSEMBL
muscle filament sliding
G
ACTA1
actin, alpha 1, skeletal muscle
TAS
1
229,566,992
229,569,843
RGD:2290271
Reactome
G
ACTC1
actin, alpha, cardiac muscle 1
TAS
15
35,080,297
35,087,927
RGD:2290271
Reactome
G
ACTN2
actinin, alpha 2
TAS
1
236,849,770
236,927,558
RGD:2290271
Reactome
G
ACTN3
actinin, alpha 3
TAS
11
66,314,312
66,330,799
RGD:2290271
Reactome
G
DES
desmin
TAS
2
220,283,099
220,291,461
RGD:2290271
Reactome
G
DMD
dystrophin
TAS
X
31,137,345
33,357,726
RGD:2290271
Reactome
G
MYBPC1
myosin binding protein C, slow type
TAS
12
101,988,709
102,079,658
RGD:2290271
Reactome
G
MYBPC2
myosin binding protein C, fast type
TAS
19
50,936,160
50,969,583
RGD:2290271
Reactome
G
MYBPC3
myosin binding protein C, cardiac
TAS
11
47,352,957
47,374,253
RGD:2290271
Reactome
G
MYH2
myosin, heavy chain 2, skeletal muscle, adult
NAS
17
10,424,465
10,453,017
RGD:2290271
BHF-UCL
G
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
TAS
17
10,531,843
10,560,626
RGD:2290271
Reactome
G
MYH4
myosin, heavy chain 4, skeletal muscle
NAS
17
10,346,607
10,372,876
RGD:2290271
BHF-UCL
G
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
IMP
14
23,851,199
23,877,486
RGD:2290271
HGNC
G
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
TAS
14
23,851,199
23,877,486
RGD:2290271
Reactome
G
MYH7
myosin, heavy chain 7, cardiac muscle, beta
IMP
14
23,881,947
23,903,496
RGD:2290271
HGNC
G
MYH7
myosin, heavy chain 7, cardiac muscle, beta
IMP
14
23,881,947
23,903,496
RGD:2290271
HGNC
G
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
TAS
17
10,293,642
10,325,267
RGD:2290271
Reactome
G
MYL1
myosin, light chain 1, alkali; skeletal, fast
NAS
2
211,154,868
211,179,895
RGD:2290271
BHF-UCL
G
MYL1
myosin, light chain 1, alkali; skeletal, fast
TAS
2
211,154,868
211,179,895
RGD:2290271
Reactome
G
MYL2
myosin, light chain 2, regulatory, cardiac, slow
TAS
12
111,348,623
111,358,404
RGD:2290271
Reactome
G
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
TAS
3
46,899,357
46,904,973
RGD:2290271
Reactome
G
MYL4
myosin, light chain 4, alkali; atrial, embryonic
TAS
17
45,286,428
45,301,045
RGD:2290271
Reactome
G
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
TAS
12
56,552,045
56,555,366
RGD:2290271
HGNC
G
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
TAS
12
56,546,204
56,551,771
RGD:2290271
HGNC
G
NEB
nebulin
TAS
2
152,341,853
152,591,001
RGD:2290271
Reactome
G
TCAP
titin-cap
TAS
17
37,821,599
37,822,807
RGD:2290271
Reactome
G
TMOD1
tropomodulin 1
TAS
9
100,263,462
100,364,025
RGD:2290271
Reactome
G
TNNC1
troponin C type 1 (slow)
TAS
3
52,485,107
52,488,057
RGD:2290271
Reactome
G
TNNC2
troponin C type 2 (fast)
TAS
20
44,451,853
44,455,953
RGD:2290271
Reactome
G
TNNI1
troponin I type 1 (skeletal, slow)
TAS
1
201,372,895
201,390,874
RGD:2290271
Reactome
G
TNNI2
troponin I type 2 (skeletal, fast)
TAS
11
1,860,233
1,862,910
RGD:2290271
Reactome
G
TNNI3
troponin I type 3 (cardiac)
TAS
19
55,663,135
55,669,100
RGD:2290271
Reactome
G
TNNT1
troponin T type 1 (skeletal, slow)
TAS
19
55,644,161
55,660,606
RGD:2290271
Reactome
G
TNNT2
troponin T type 2 (cardiac)
IDA
1
201,328,142
201,346,805
RGD:2290271
UniProtKB
G
TNNT2
troponin T type 2 (cardiac)
IDA
1
201,328,142
201,346,805
RGD:2290271
UniProtKB
G
TNNT2
troponin T type 2 (cardiac)
TAS
1
201,328,142
201,346,805
RGD:2290271
Reactome
G
TNNT3
troponin T type 3 (skeletal, fast)
TAS
11
1,940,799
1,959,936
RGD:2290271
Reactome
G
TPM1
tropomyosin 1 (alpha)
ISS
15
63,334,838
63,364,114
RGD:2290271
BHF-UCL
G
TPM1
tropomyosin 1 (alpha)
TAS
15
63,334,838
63,364,114
RGD:2290271
Reactome
G
TPM1
tropomyosin 1 (alpha)
IEA
15
63,334,838
63,364,114
RGD:2290271
ENSEMBL
G
TPM2
tropomyosin 2 (beta)
TAS
9
35,681,990
35,690,053
RGD:2290271
Reactome
G
TPM3
tropomyosin 3
TAS
1
154,127,780
154,164,609
RGD:2290271
Reactome
G
TPM4
tropomyosin 4
TAS
19
16,178,317
16,213,813
RGD:2290271
Reactome
G
TTN
titin
TAS
2
179,390,716
179,672,150
RGD:2290271
Reactome
G
VIM
vimentin
TAS
10
17,270,258
17,279,592
RGD:2290271
Reactome
negative regulation of cardiac muscle contraction
G
ADORA1
adenosine A1 receptor
IEA
1
203,096,836
203,136,533
RGD:2290271
ENSEMBL
G
PDE5A
phosphodiesterase 5A, cGMP-specific
IEA
4
120,415,550
120,549,981
RGD:2290271
ENSEMBL
G
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
TAS
7
106,505,924
106,547,592
RGD:2290271
UniProtKB
negative regulation of muscle contraction
G
TNNT1
troponin T type 1 (skeletal, slow)
IDA
19
55,644,161
55,660,606
RGD:2290271
UniProtKB
negative regulation of smooth muscle contraction
G
ADRB1
adrenoceptor beta 1
IEA
10
115,803,806
115,806,667
RGD:2290271
ENSEMBL
G
ADRB2
adrenoceptor beta 2, surface
IEA
5
148,206,156
148,208,197
RGD:2290271
ENSEMBL
G
CALCA
calcitonin-related polypeptide alpha
IEA
11
14,988,215
14,993,832
RGD:2290271
ENSEMBL
G
NCF1
neutrophil cytosolic factor 1
IEA
7
74,188,309
74,203,659
RGD:2290271
ENSEMBL
G
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
IEA
1
186,640,944
186,649,559
RGD:2290271
ENSEMBL
negative regulation of striated muscle contraction
G
ADRBK1
adrenergic, beta, receptor kinase 1
IMP
11
67,033,905
67,054,029
RGD:2290271
BHF-UCL
G
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
IEA
1
160,085,520
160,113,381
RGD:2290271
ENSEMBL
G
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
IMP
16
28,889,809
28,915,830
RGD:2290271
UniProtKB
negative regulation of uterine smooth muscle contraction
G
ADRA2A
adrenoceptor alpha 2A
IEA
10
112,836,790
112,840,665
RGD:2290271
ENSEMBL
G
ADRA2C
adrenoceptor alpha 2C
IEA
4
3,768,296
3,770,253
RGD:2290271
ENSEMBL
peristalsis
G
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
IEA
1
230,838,269
230,850,336
RGD:2290271
ENSEMBL
G
DLG1
discs, large homolog 1 (Drosophila)
IEA
3
196,769,431
197,025,447
RGD:2290271
ENSEMBL
G
DRD1
dopamine receptor D1
IEA
5
174,867,675
174,871,163
RGD:2290271
ENSEMBL
G
DRD2
dopamine receptor D2
ISS
11
113,280,317
113,346,001
RGD:2290271
BHF-UCL
G
DRD2
dopamine receptor D2
IEA
11
113,280,317
113,346,001
RGD:2290271
ENSEMBL
G
GDNF
glial cell derived neurotrophic factor
ISS
5
37,812,779
37,839,782
RGD:2290271
UniProtKB
G
P2RX2
purinergic receptor P2X, ligand-gated ion channel, 2
IEA
12
133,195,403
133,198,972
RGD:2290271
ENSEMBL
G
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
IEA
11
57,105,841
57,137,549
RGD:2290271
ENSEMBL
G
SSTR2
somatostatin receptor 2
IEA
17
71,161,160
71,168,094
RGD:2290271
ENSEMBL
positive regulation of cardiac muscle contraction
G
ADRA1A
adrenoceptor alpha 1A
ISS
8
26,605,667
26,722,922
RGD:2290271
BHF-UCL
G
CTGF
connective tissue growth factor
IEA
6
132,269,316
132,272,518
RGD:2290271
ENSEMBL
G
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
IEA
14
102,547,075
102,606,086
RGD:2290271
ENSEMBL
G
RGS2
regulator of G-protein signaling 2, 24kDa
ISS
1
192,778,169
192,781,407
RGD:2290271
BHF-UCL
G
UCN
urocortin
IEA
2
27,530,265
27,531,130
RGD:2290271
ENSEMBL
positive regulation of fast-twitch skeletal muscle fiber contraction
G
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
IDA
16
28,889,809
28,915,830
RGD:2290271
UniProtKB
positive regulation of hindgut contraction
G
OXT
oxytocin/neurophysin I prepropeptide
IEA
20
3,052,266
3,053,162
RGD:2290271
ENSEMBL
positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction
G
RYR2
ryanodine receptor 2 (cardiac)
ISS
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
IEA
1
237,205,702
237,997,288
RGD:2290271
ENSEMBL
positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
G
GSTO1
glutathione S-transferase omega 1
IC
10
106,013,952
106,027,222
RGD:2290271
BHF-UCL
positive regulation of smooth muscle contraction
G
ADA
adenosine deaminase
IEA
20
43,248,163
43,280,376
RGD:2290271
ENSEMBL
G
ADRA1A
adrenoceptor alpha 1A
IEA
8
26,605,667
26,722,922
RGD:2290271
ENSEMBL
G
ADRA1A
adrenoceptor alpha 1A
IEA
8
26,605,667
26,722,922
RGD:2290271
ENSEMBL
G
CHRM3
cholinergic receptor, muscarinic 3
IEA
1
239,792,373
240,072,720
RGD:2290271
ENSEMBL
G
CHRM3
cholinergic receptor, muscarinic 3
IEA
1
239,792,373
240,072,720
RGD:2290271
ENSEMBL
G
EDN1
endothelin 1
IEA
6
12,290,529
12,297,427
RGD:2290271
ENSEMBL
G
EDN2
endothelin 2
IEA
1
41,944,446
41,950,344
RGD:2290271
ENSEMBL
G
F2R
coagulation factor II (thrombin) receptor
ISS
5
76,011,868
76,031,595
RGD:2290271
UniProtKB
G
MYOCD
myocardin
IDA
17
12,569,207
12,670,651
RGD:2290271
BHF-UCL
G
NMU
neuromedin U
IEA
4
56,461,398
56,502,465
RGD:2290271
ENSEMBL
G
NPNT
nephronectin
IEA
4
106,816,597
106,892,828
RGD:2290271
ENSEMBL
G
PROK2
prokineticin 2
IDA
3
71,820,806
71,834,357
RGD:2290271
UniProtKB
G
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
IEA
1
186,640,944
186,649,559
RGD:2290271
ENSEMBL
G
SPHK1
sphingosine kinase 1
IDA
17
74,380,690
74,383,941
RGD:2290271
UniProtKB
G
SRF
serum response factor (c-fos serum response element-binding transcription factor)
IDA
6
43,138,920
43,149,244
RGD:2290271
BHF-UCL
G
TBXA2R
thromboxane A2 receptor
IEA
19
3,594,504
3,606,831
RGD:2290271
ENSEMBL
positive regulation of striated muscle contraction
G
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
IEA
1
116,915,795
116,947,396
RGD:2290271
ENSEMBL
positive regulation of uterine smooth muscle contraction
G
ADRA2B
adrenoceptor alpha 2B
IEA
2
96,778,623
96,781,888
RGD:2290271
ENSEMBL
G
LCK
lymphocyte-specific protein tyrosine kinase
IEA
1
32,716,840
32,751,766
RGD:2290271
ENSEMBL
G
OXT
oxytocin/neurophysin I prepropeptide
IEA
20
3,052,266
3,053,162
RGD:2290271
ENSEMBL
G
OXTR
oxytocin receptor
IEA
3
8,792,094
8,811,300
RGD:2290271
ENSEMBL
G
TACR1
tachykinin receptor 1
IEA
2
75,273,590
75,426,645
RGD:2290271
ENSEMBL
G
TACR2
tachykinin receptor 2
IEA
10
71,163,958
71,176,674
RGD:2290271
ENSEMBL
G
TACR3
tachykinin receptor 3
IEA
4
104,510,625
104,640,973
RGD:2290271
ENSEMBL
regulation of atrial cardiac muscle cell action potential
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
IEA
4
113,739,239
114,304,896
RGD:2290271
ENSEMBL
G
GJA1
gap junction protein, alpha 1, 43kDa
TAS
6
121,756,745
121,770,873
RGD:2290271
BHF-UCL
G
GJA5
gap junction protein, alpha 5, 40kDa
IMP
1
147,228,332
147,245,484
RGD:2290271
BHF-UCL
G
GJC1
gap junction protein, gamma 1, 45kDa
TAS
17
42,875,816
42,908,179
RGD:2290271
BHF-UCL
G
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
IMP
12
5,153,085
5,155,954
RGD:2290271
BHF-UCL
G
NUP155
nucleoporin 155kDa
IEA
5
37,291,941
37,371,197
RGD:2290271
ENSEMBL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IMP
11
123,499,895
123,525,315
RGD:2290271
BHF-UCL
regulation of cardiac muscle cell action potential involved in contraction
G
PKP2
plakophilin 2
IMP
12
32,943,680
33,049,780
RGD:2290271
BHF-UCL
G
SCN1B
sodium channel, voltage-gated, type I, beta subunit
IMP
19
35,521,592
35,531,353
RGD:2290271
BHF-UCL
G
SCN2B
sodium channel, voltage-gated, type II, beta subunit
IMP
11
118,033,519
118,047,337
RGD:2290271
BHF-UCL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IMP
11
123,499,895
123,525,315
RGD:2290271
BHF-UCL
G
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
IMP
11
118,004,092
118,023,630
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
regulation of cardiac muscle cell contraction
G
ADRB1
adrenoceptor beta 1
IEA
10
115,803,806
115,806,667
RGD:2290271
ENSEMBL
G
ANK2
ankyrin 2, neuronal
IGI
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
IEA
1
116,915,795
116,947,396
RGD:2290271
ENSEMBL
G
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
IEA
1
160,085,520
160,113,381
RGD:2290271
ENSEMBL
G
PLN
phospholamban
IC
6
118,869,442
118,881,587
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IEA
3
38,589,553
38,691,164
RGD:2290271
ENSEMBL
G
SRI
sorcin
IMP
7
87,834,432
87,856,308
RGD:2290271
BHF-UCL
G
SRI
sorcin
IMP
7
87,834,432
87,856,308
RGD:2290271
BHF-UCL
regulation of cardiac muscle contraction
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
BMP10
bone morphogenetic protein 10
IMP
2
69,092,613
69,098,649
RGD:2290271
BHF-UCL
G
CALM1
calmodulin 1 (phosphorylase kinase, delta)
IMP
14
90,863,327
90,874,619
RGD:2290271
BHF-UCL
G
CALM2
calmodulin 2 (phosphorylase kinase, delta)
IMP
2
47,387,221
47,403,740
RGD:2290271
BHF-UCL
G
CALM3
calmodulin 3 (phosphorylase kinase, delta)
IMP
19
47,104,512
47,114,039
RGD:2290271
BHF-UCL
G
CAV3
caveolin 3
IMP
3
8,775,486
8,788,451
RGD:2290271
BHF-UCL
G
GJA5
gap junction protein, alpha 5, 40kDa
IMP
1
147,228,332
147,245,484
RGD:2290271
BHF-UCL
G
GJA5
gap junction protein, alpha 5, 40kDa
IMP
1
147,228,332
147,245,484
RGD:2290271
BHF-UCL
G
GJA5
gap junction protein, alpha 5, 40kDa
IMP
1
147,228,332
147,245,484
RGD:2290271
BHF-UCL
G
NKX2-5
NK2 homeobox 5
ISS
5
172,659,107
172,662,315
RGD:2290271
BHF-UCL
G
NOS1
nitric oxide synthase 1 (neuronal)
TAS
12
117,645,947
117,799,607
RGD:2290271
BHF-UCL
G
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
IMP
12
121,647,664
121,671,909
RGD:2290271
BHF-UCL
G
P2RX4
purinergic receptor P2X, ligand-gated ion channel, 4
IMP
12
121,647,664
121,671,909
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
IMP
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
SCN10A
sodium channel, voltage-gated, type X, alpha subunit
IMP
3
38,738,837
38,835,501
RGD:2290271
BHF-UCL
G
SMAD7
SMAD family member 7
ISS
18
46,446,223
46,477,081
RGD:2290271
BHF-UCL
G
SMAD7
SMAD family member 7
IEA
18
46,446,223
46,477,081
RGD:2290271
ENSEMBL
regulation of cardiac muscle contraction by calcium ion signaling
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
IEA
4
113,739,239
114,304,896
RGD:2290271
ENSEMBL
G
HDAC4
histone deacetylase 4
IEA
2
239,969,864
240,322,643
RGD:2290271
ENSEMBL
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G
ANK2
ankyrin 2, neuronal
IGI
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ANK2
ankyrin 2, neuronal
ISS
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
ASPH
aspartate beta-hydroxylase
ISS
8
62,413,115
62,627,199
RGD:2290271
BHF-UCL
G
ASPH
aspartate beta-hydroxylase
TAS
8
62,413,115
62,627,199
RGD:2290271
BHF-UCL
G
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
TAS
12
2,162,416
2,807,115
RGD:2290271
BHF-UCL
G
CALM1
calmodulin 1 (phosphorylase kinase, delta)
IC
14
90,863,327
90,874,619
RGD:2290271
BHF-UCL
G
CALM2
calmodulin 2 (phosphorylase kinase, delta)
IC
2
47,387,221
47,403,740
RGD:2290271
BHF-UCL
G
CALM3
calmodulin 3 (phosphorylase kinase, delta)
IC
19
47,104,512
47,114,039
RGD:2290271
BHF-UCL
G
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
TAS
4
114,372,188
114,683,083
RGD:2290271
UniProtKB
G
CASQ2
calsequestrin 2 (cardiac muscle)
IMP
1
116,242,624
116,311,426
RGD:2290271
BHF-UCL
G
CASQ2
calsequestrin 2 (cardiac muscle)
IMP
1
116,242,624
116,311,426
RGD:2290271
BHF-UCL
G
CLIC2
chloride intracellular channel 2
IC
X
154,505,500
154,563,986
RGD:2290271
BHF-UCL
G
DMD
dystrophin
ISS
X
31,137,345
33,357,726
RGD:2290271
BHF-UCL
G
FKBP1B
FK506 binding protein 1B, 12.6 kDa
ISS
2
24,272,584
24,286,551
RGD:2290271
BHF-UCL
G
FKBP1B
FK506 binding protein 1B, 12.6 kDa
IEA
2
24,272,584
24,286,551
RGD:2290271
ENSEMBL
G
GSTM2
glutathione S-transferase mu 2 (muscle)
IC
1
110,210,644
110,226,619
RGD:2290271
BHF-UCL
G
GSTM2
glutathione S-transferase mu 2 (muscle)
IC
1
110,210,644
110,226,619
RGD:2290271
BHF-UCL
G
GSTO1
glutathione S-transferase omega 1
IC
10
106,013,952
106,027,222
RGD:2290271
BHF-UCL
G
HRC
histidine rich calcium binding protein
TAS
19
49,654,455
49,658,681
RGD:2290271
BHF-UCL
G
PLN
phospholamban
IEA
6
118,869,442
118,881,587
RGD:2290271
ENSEMBL
G
RYR2
ryanodine receptor 2 (cardiac)
ISS
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
IC
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
IEA
1
237,205,702
237,997,288
RGD:2290271
ENSEMBL
G
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
ISS
2
40,339,286
40,739,575
RGD:2290271
BHF-UCL
G
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
IEA
2
40,339,286
40,739,575
RGD:2290271
ENSEMBL
regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction
G
DMPK
dystrophia myotonica-protein kinase
IEA
19
46,272,975
46,285,815
RGD:2290271
ENSEMBL
regulation of hindgut contraction
G
GHSR
growth hormone secretagogue receptor
IEA
3
172,161,081
172,166,246
RGD:2290271
ENSEMBL
regulation of muscle contraction
G
ANXA6
annexin A6
IEA
5
150,480,267
150,537,443
RGD:2290271
ENSEMBL
G
CALCRL
calcitonin receptor-like
IEA
2
188,207,846
188,313,021
RGD:2290271
ENSEMBL
G
MYL5
myosin, light chain 5, regulatory
TAS
4
671,711
675,817
RGD:2290271
PINC
G
MYL9
myosin, light chain 9, regulatory
TAS
20
35,169,887
35,178,226
RGD:2290271
PINC
G
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
TAS
1
202,317,830
202,557,697
RGD:2290271
PINC
G
PRKCA
protein kinase C, alpha
IEA
17
64,298,926
64,806,862
RGD:2290271
ENSEMBL
G
SSTR2
somatostatin receptor 2
IEA
17
71,161,160
71,168,094
RGD:2290271
ENSEMBL
G
TNNC1
troponin C type 1 (slow)
IDA
3
52,485,107
52,488,057
RGD:2290271
BHF-UCL
G
TNNC1
troponin C type 1 (slow)
TAS
3
52,485,107
52,488,057
RGD:2290271
UniProtKB
G
TNNC2
troponin C type 2 (fast)
TAS
20
44,451,853
44,455,953
RGD:2290271
PINC
G
TPM1
tropomyosin 1 (alpha)
TAS
15
63,334,838
63,364,114
RGD:2290271
PINC
G
TPM3
tropomyosin 3
NAS
1
154,127,780
154,164,609
RGD:2290271
UniProtKB
regulation of muscle filament sliding
G
MYBPC3
myosin binding protein C, cardiac
ISS
11
47,352,957
47,374,253
RGD:2290271
BHF-UCL
G
MYLK2
myosin light chain kinase 2
IDA
20
30,407,178
30,422,500
RGD:2290271
BHF-UCL
regulation of muscle filament sliding speed
G
TNNC1
troponin C type 1 (slow)
ISS
3
52,485,107
52,488,057
RGD:2290271
BHF-UCL
G
TNNC1
troponin C type 1 (slow)
IEA
3
52,485,107
52,488,057
RGD:2290271
ENSEMBL
regulation of skeletal muscle contraction
G
CAV3
caveolin 3
IMP
3
8,775,486
8,788,451
RGD:2290271
BHF-UCL
G
DMD
dystrophin
ISS
X
31,137,345
33,357,726
RGD:2290271
BHF-UCL
regulation of skeletal muscle contraction by calcium ion signaling
G
DMPK
dystrophia myotonica-protein kinase
IEA
19
46,272,975
46,285,815
RGD:2290271
ENSEMBL
regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
G
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
IEA
1
160,160,285
160,171,676
RGD:2290271
ENSEMBL
G
DMD
dystrophin
ISS
X
31,137,345
33,357,726
RGD:2290271
BHF-UCL
G
GSTM2
glutathione S-transferase mu 2 (muscle)
IC
1
110,210,644
110,226,619
RGD:2290271
BHF-UCL
regulation of smooth muscle contraction
G
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
IEA
1
160,085,520
160,113,381
RGD:2290271
ENSEMBL
G
CAV1
caveolin 1, caveolae protein, 22kDa
ISS
7
116,164,839
116,201,239
RGD:2290271
BHF-UCL
G
CAV1
caveolin 1, caveolae protein, 22kDa
IEA
7
116,164,839
116,201,239
RGD:2290271
ENSEMBL
G
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
ISS
15
78,885,394
78,913,637
RGD:2290271
UniProtKB
G
CHRNB4
cholinergic receptor, nicotinic, beta 4 (neuronal)
IEA
15
78,916,636
78,933,587
RGD:2290271
ENSEMBL
G
CNN1
calponin 1, basic, smooth muscle
TAS
19
11,649,579
11,661,138
RGD:2290271
UniProtKB
G
DAPK3
death-associated protein kinase 3
TAS
19
3,958,452
3,969,826
RGD:2290271
UniProtKB
G
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
TAS
8
73,449,626
73,850,584
RGD:2290271
PINC
G
NMU
neuromedin U
IEA
4
56,461,398
56,502,465
RGD:2290271
InterPro
G
NMU
neuromedin U
TAS
4
56,461,398
56,502,465
RGD:2290271
PINC
G
NMUR2
neuromedin U receptor 2
NAS
5
151,771,102
151,784,840
RGD:2290271
UniProtKB
G
PLCE1
phospholipase C, epsilon 1
TAS
10
95,753,746
96,088,149
RGD:2290271
UniProtKB
G
TNNI3
troponin I type 3 (cardiac)
IEA
19
55,663,135
55,669,100
RGD:2290271
ENSEMBL
regulation of striated muscle contraction
G
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
NAS
1
160,085,520
160,113,381
RGD:2290271
UniProtKB
G
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
IMP
16
28,889,809
28,915,830
RGD:2290271
UniProtKB
G
MYBPC3
myosin binding protein C, cardiac
ISS
11
47,352,957
47,374,253
RGD:2290271
BHF-UCL
G
MYBPH
myosin binding protein H
TAS
1
203,136,939
203,144,942
RGD:2290271
PINC
G
MYL2
myosin, light chain 2, regulatory, cardiac, slow
TAS
12
111,348,623
111,358,404
RGD:2290271
PINC
G
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
IMP
3
46,899,357
46,904,973
RGD:2290271
BHF-UCL
G
SRI
sorcin
TAS
7
87,834,432
87,856,308
RGD:2290271
PINC
G
TNNI1
troponin I type 1 (skeletal, slow)
NAS
1
201,372,895
201,390,874
RGD:2290271
UniProtKB
G
TNNT3
troponin T type 3 (skeletal, fast)
IDA
11
1,940,799
1,959,936
RGD:2290271
UniProtKB
regulation of vascular smooth muscle contraction
G
ADRA2B
adrenoceptor alpha 2B
IEA
2
96,778,623
96,781,888
RGD:2290271
ENSEMBL
G
CHRM3
cholinergic receptor, muscarinic 3
IEA
1
239,792,373
240,072,720
RGD:2290271
ENSEMBL
G
MAP2K1
mitogen-activated protein kinase kinase 1
IEA
15
66,679,211
66,783,882
RGD:2290271
ENSEMBL
G
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
IEA
17
3,799,885
3,819,960
RGD:2290271
ENSEMBL
regulation of ventricular cardiac muscle cell action potential
G
ANK2
ankyrin 2, neuronal
IMP
4
113,739,239
114,304,896
RGD:2290271
BHF-UCL
G
DSC2
desmocollin 2
IMP
18
28,645,942
28,682,388
RGD:2290271
BHF-UCL
G
DSG2
desmoglein 2
IMP
18
29,078,027
29,128,814
RGD:2290271
BHF-UCL
G
DSP
desmoplakin
IMP
6
7,541,870
7,586,946
RGD:2290271
BHF-UCL
G
GJA5
gap junction protein, alpha 5, 40kDa
IEA
1
147,228,332
147,245,484
RGD:2290271
ENSEMBL
G
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
IMP
3
32,148,003
32,210,207
RGD:2290271
BHF-UCL
G
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
IMP
3
32,148,003
32,210,207
RGD:2290271
BHF-UCL
G
JUP
junction plakoglobin
IMP
17
39,910,859
39,942,964
RGD:2290271
BHF-UCL
G
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
IEA
21
35,736,323
35,743,440
RGD:2290271
ENSEMBL
G
PKP2
plakophilin 2
IMP
12
32,943,680
33,049,780
RGD:2290271
BHF-UCL
G
PKP2
plakophilin 2
IMP
12
32,943,680
33,049,780
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
ISS
1
237,205,702
237,997,288
RGD:2290271
BHF-UCL
G
RYR2
ryanodine receptor 2 (cardiac)
IEA
1
237,205,702
237,997,288
RGD:2290271
ENSEMBL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IMP
11
123,499,895
123,525,315
RGD:2290271
BHF-UCL
G
SCN3B
sodium channel, voltage-gated, type III, beta subunit
IEA
11
123,499,895
123,525,315
RGD:2290271
ENSEMBL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
G
SCN5A
sodium channel, voltage-gated, type V, alpha subunit
IMP
3
38,589,553
38,691,164
RGD:2290271
BHF-UCL
relaxation of vascular smooth muscle
G
ADORA1
adenosine A1 receptor
IEA
1
203,096,836
203,136,533
RGD:2290271
ENSEMBL
G
ADORA2B
adenosine A2b receptor
IEA
17
15,848,231
15,879,210
RGD:2290271
ENSEMBL
G
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
IEA
4
156,587,862
156,658,214
RGD:2290271
ENSEMBL
G
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
IEA
10
78,629,359
79,397,577
RGD:2290271
ENSEMBL
G
RGS2
regulator of G-protein signaling 2, 24kDa
IEA
1
192,778,169
192,781,407
RGD:2290271
ENSEMBL
G
SOD1
superoxide dismutase 1, soluble
ISS
21
33,031,935
33,041,244
RGD:2290271
UniProtKB
skeletal muscle contraction
G
CCDC78
coiled-coil domain containing 78
IMP
16
772,582
776,473
RGD:2290271
UniProtKB
G
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
IMP
2
175,612,320
175,629,200
RGD:2290271
BHF-UCL
G
CHUK
conserved helix-loop-helix ubiquitous kinase
IEA
10
101,948,124
101,989,344
RGD:2290271
ENSEMBL
G
HOMER1
homer homolog 1 (Drosophila)
IEA
5
78,669,786
78,809,700
RGD:2290271
ENSEMBL
G
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
IEA
14
102,547,075
102,606,086
RGD:2290271
ENSEMBL
G
JSRP1
junctional sarcoplasmic reticulum protein 1
IDA
19
2,252,250
2,256,422
RGD:2290271
UniProtKB
G
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
IEA
17
57,970,443
58,027,787
RGD:2290271
ENSEMBL
G
TCAP
titin-cap
IEP
17
37,821,599
37,822,807
RGD:2290271
BHF-UCL
G
TNF
tumor necrosis factor
IEA
6
31,543,344
31,546,113
RGD:2290271
ENSEMBL
G
TNNC2
troponin C type 2 (fast)
IDA
20
44,451,853
44,455,953
RGD:2290271
UniProtKB
G
TNNI2
troponin I type 2 (skeletal, fast)
IDA
11
1,860,233
1,862,910
RGD:2290271
UniProtKB
G
TNNT1
troponin T type 1 (skeletal, slow)
IMP
19
55,644,161
55,660,606
RGD:2290271
UniProtKB
G
TNNT3
troponin T type 3 (skeletal, fast)
IDA
11
1,940,799
1,959,936
RGD:2290271
UniProtKB
slow-twitch skeletal muscle fiber contraction
G
MB
myoglobin
IEA
22
36,002,811
36,019,401
RGD:2290271
ENSEMBL
smooth muscle contraction
G
ADRA1A
adrenoceptor alpha 1A
TAS
8
26,605,667
26,722,922
RGD:2290271
PINC
G
BDKRB2
bradykinin receptor B2
IC
14
96,671,135
96,710,666
RGD:2290271
BHF-UCL
G
CHRM3
cholinergic receptor, muscarinic 3
IEA
1
239,792,373
240,072,720
RGD:2290271
ENSEMBL
G
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
ISS
1
154,540,257
154,552,354
RGD:2290271
UniProtKB
G
CHRNB4
cholinergic receptor, nicotinic, beta 4 (neuronal)
IEA
15
78,916,636
78,933,587
RGD:2290271
ENSEMBL
G
CNN3
calponin 3, acidic
NAS
1
95,362,507
95,392,735
RGD:2290271
UniProtKB
G
EDNRA
endothelin receptor type A
NAS
4
148,402,069
148,466,106
RGD:2290271
UniProtKB
G
FKBP1B
FK506 binding protein 1B, 12.6 kDa
IEA
2
24,272,584
24,286,551
RGD:2290271
ENSEMBL
G
GAL
galanin/GMAP prepropeptide
NAS
11
68,451,983
68,458,643
RGD:2290271
UniProtKB
G
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IEA
13
47,405,677
47,471,211
RGD:2290271
InterPro
G
HTR7
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IEA
10
92,500,575
92,617,671
RGD:2290271
InterPro
G
KNG1
kininogen 1
TAS
3
186,435,098
186,462,199
RGD:2290271
UniProtKB
G
MYH11
myosin, heavy chain 11, smooth muscle
ISS
16
15,796,992
15,950,887
RGD:2290271
UniProtKB
G
MYL7
myosin, light chain 7, regulatory
NAS
7
44,178,463
44,180,916
RGD:2290271
UniProtKB
G
MYLK
myosin light chain kinase
ISS
3
123,331,143
123,603,149
RGD:2290271
UniProtKB
G
NMUR1
neuromedin U receptor 1
IEP
2
232,387,871
232,395,182
RGD:2290271
UniProtKB
G
PDE4D
phosphodiesterase 4D, cAMP-specific
IEA
5
58,264,865
59,783,925
RGD:2290271
ENSEMBL
G
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
TAS
18
18,529,701
18,691,812
RGD:2290271
UniProtKB
G
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
TAS
2
11,321,778
11,484,711
RGD:2290271
UniProtKB
G
SMTN
smoothelin
TAS
22
31,477,282
31,500,610
RGD:2290271
PINC
G
TPCN2
two pore segment channel 2
ISS
11
68,816,350
68,858,072
RGD:2290271
UniProtKB
G
TPCN2
two pore segment channel 2
IEA
11
68,816,350
68,858,072
RGD:2290271
ENSEMBL
smooth muscle contraction involved in micturition
G
CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
IEA
12
2,162,416
2,807,115
RGD:2290271
ENSEMBL
G
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
IDA
10
78,629,359
79,397,577
RGD:2290271
UniProtKB
G
TACR1
tachykinin receptor 1
IEA
2
75,273,590
75,426,645
RGD:2290271
ENSEMBL
striated muscle contraction
G
ALDOA
aldolase A, fructose-bisphosphate
IMP
16
30,064,411
30,081,741
RGD:2290271
BHF-UCL
G
ARG2
arginase, type II
IEA
14
68,086,579
68,118,437
RGD:2290271
ENSEMBL
G
ARHGEF11
Rho guanine nucleotide exchange factor (GEF) 11
NAS
1
156,904,632
157,015,162
RGD:2290271
UniProtKB
G
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
IEA
1
201,008,640
201,081,694
RGD:2290271
ENSEMBL
G
CASQ2
calsequestrin 2 (cardiac muscle)
TAS
1
116,242,624
116,311,426
RGD:2290271
PINC
G
DTNA
dystrobrevin, alpha
TAS
18
32,073,254
32,471,808
RGD:2290271
PINC
G
ID2B
inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
NAS
3
62,109,097
62,110,392
RGD:2290271
UniProtKB
G
KLHL41
kelch-like family member 41
TAS
2
170,366,212
170,382,772
RGD:2290271
PINC
G
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
ISS
14
23,851,199
23,877,486
RGD:2290271
BHF-UCL
G
MYLK2
myosin light chain kinase 2
IDA
20
30,407,178
30,422,500
RGD:2290271
BHF-UCL
G
NOS1
nitric oxide synthase 1 (neuronal)
IEA
12
117,645,947
117,799,607
RGD:2290271
ENSEMBL
G
PGAM2
phosphoglycerate mutase 2 (muscle)
IMP
7
44,102,326
44,105,186
RGD:2290271
UniProtKB
G
RYR3
ryanodine receptor 3
IEA
15
33,603,177
34,158,303
RGD:2290271
ENSEMBL
G
SMPX
small muscle protein, X-linked
TAS
X
21,724,090
21,776,278
RGD:2290271
PINC
G
TTN
titin
TAS
2
179,390,716
179,672,150
RGD:2290271
UniProtKB
tonic smooth muscle contraction
G
MYLK
myosin light chain kinase
ISS
3
123,331,143
123,603,149
RGD:2290271
UniProtKB
ureteric peristalsis
G
TSHZ3
teashirt zinc finger homeobox 3
IEA
19
31,765,851
31,840,190
RGD:2290271
ENSEMBL
urinary bladder smooth muscle contraction
G
P2RX2
purinergic receptor P2X, ligand-gated ion channel, 2
IEA
12
133,195,403
133,198,972
RGD:2290271
ENSEMBL
G
P2RX3
purinergic receptor P2X, ligand-gated ion channel, 3
IEA
11
57,105,841
57,137,549
RGD:2290271
ENSEMBL
G
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
IEA
22
38,507,502
38,577,836
RGD:2290271
ENSEMBL
vascular smooth muscle contraction
G
ACTA2
actin, alpha 2, smooth muscle, aorta
IEA
10
90,694,831
90,751,147
RGD:2290271
ENSEMBL
G
PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
TAS
11
17,108,122
17,191,354
RGD:2290271
UniProtKB
G
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
ISS
2
40,339,286
40,739,575
RGD:2290271
BHF-UCL
vein smooth muscle contraction
G
EDN1
endothelin 1
IDA
6
12,290,529
12,297,427
RGD:2290271
BHF-UCL
G
EDN2
endothelin 2
IDA
1
41,944,446
41,950,344
RGD:2290271
BHF-UCL
G
EDN2
endothelin 2
IDA
1
41,944,446
41,950,344
RGD:2290271
BHF-UCL
G
EDN3
endothelin 3
IDA
20
57,875,499
57,901,047
RGD:2290271
BHF-UCL
G
EDNRB
endothelin receptor type B
IMP
13 13
78,469,616 78,513,393
78,549,664 78,549,674
RGD:2290271
BHF-UCL
Term paths to the root one longest all shortest one shortest all one shortest and longest all longest