ONTOLOGY REPORT - ANNOTATIONS


Term:activation-induced cell death of T cells
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Accession:GO:0006924 term browser browse the term
Definition:A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.
Synonyms:exact_synonym: activation-induced cell death of T lymphocytes
 broad_synonym: AICD;   activated T cell apoptosis;   antigen-driven apoptosis


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activation-induced cell death of T cells term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link ISO 6 137,640,482 137,657,552 RGD:1624291 RGD
G Akt1 v-akt murine thymoma viral oncogene homolog 1 GBrowse link IEA 6 137,640,482 137,657,552 RGD:1600115 ENSEMBL
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link ISO 10 10,984,721 11,009,374 RGD:1624291 RGD
G Dnaja3 DnaJ (Hsp40) homolog, subfamily A, member 3 GBrowse link IEA 10 10,984,721 11,009,374 RGD:1600115 ENSEMBL
G Fas Fas cell surface death receptor GBrowse link ISO 1 238,259,443 238,274,745 RGD:1624291 RGD
G Fas Fas cell surface death receptor GBrowse link ISO 1 238,259,443 238,274,745 RGD:1624291 RGD
G Fas Fas cell surface death receptor GBrowse link ISO 1 238,259,443 238,274,745 RGD:1624291 RGD
G Il2ra interleukin 2 receptor, alpha GBrowse link ISO 17 78,050,491 78,097,802 RGD:1624291 RGD
G Il2ra interleukin 2 receptor, alpha GBrowse link IEA 17 78,050,491 78,097,802 RGD:1600115 ENSEMBL
G Rps6 ribosomal protein S6 GBrowse link ISO 5 106,165,612 106,168,472 RGD:1624291 RGD
G Siva1 SIVA1, apoptosis-inducing factor GBrowse link ISO 6 137,631,408 137,635,724 RGD:1624291 RGD
G Siva1 SIVA1, apoptosis-inducing factor GBrowse link IEA 6 137,631,408 137,635,724 RGD:1600115 ENSEMBL
G Tgfb2 transforming growth factor, beta 2 GBrowse link ISO 13 102,718,703 102,818,768 RGD:1624291 RGD
G Tgfb2 transforming growth factor, beta 2 GBrowse link IEA 13 102,718,703 102,818,768 RGD:1600115 ENSEMBL
negative regulation of activation-induced cell death of T cells term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial GBrowse link ISO 1 261,370,264 261,431,434 RGD:1624291 RGD
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial GBrowse link IEA 1 261,370,264 261,431,434 RGD:1600115 ENSEMBL

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Term Annotations click to browse term
  biological_process 136531
    immune system process 6166
      leukocyte homeostasis 173
        lymphocyte homeostasis 127
          T cell homeostasis 66
            activation-induced cell death of T cells 16
              negative regulation of activation-induced cell death of T cells 2
              positive regulation of activation-induced cell death of T cells 0
              regulation of activation-induced cell death of T cells + 2
Path 2
Term Annotations click to browse term
  biological_process 136531
    single-organism process 88879
      death 4762
        cell death 4749
          programmed cell death 4441
            apoptotic process 4327
              cell-type specific apoptotic process 805
                leukocyte apoptotic process 159
                  lymphocyte apoptotic process 111
                    T cell apoptotic process 62
                      activation-induced cell death of T cells 16
                        negative regulation of activation-induced cell death of T cells 2
                        positive regulation of activation-induced cell death of T cells 0
                        regulation of activation-induced cell death of T cells + 2
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