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Term:receptor-mediated endocytosis
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Accession:GO:0006898 term browser browse the term
Definition:An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
Synonyms:xref_analog: Reactome:REACT_100248;   Reactome:REACT_100330;   Reactome:REACT_103823;   Reactome:REACT_103978;   Reactome:REACT_104437;   Reactome:REACT_105792;   Reactome:REACT_106851;   Reactome:REACT_106981;   Reactome:REACT_107174;   Reactome:REACT_107413;   Reactome:REACT_107880;   Reactome:REACT_109308;   Reactome:REACT_110306;   Reactome:REACT_110472;   Reactome:REACT_110785;   Reactome:REACT_111177;   Reactome:REACT_112262;   Reactome:REACT_113143;   Reactome:REACT_113715;   Reactome:REACT_114061;   Reactome:REACT_114157;   Reactome:REACT_114755;   Reactome:REACT_114861;   Reactome:REACT_115278;   Reactome:REACT_115471;   Reactome:REACT_115520;   Reactome:REACT_28736;   Reactome:REACT_29541;   Reactome:REACT_30278;   Reactome:REACT_30568;   Reactome:REACT_30705;   Reactome:REACT_30731;   Reactome:REACT_31404;   Reactome:REACT_31638;   Reactome:REACT_33230;   Reactome:REACT_33281;   Reactome:REACT_34027;   Reactome:REACT_50314;   Reactome:REACT_50874;   Reactome:REACT_6720;   Reactome:REACT_6775;   Reactome:REACT_6810;   Reactome:REACT_6849;   Reactome:REACT_6860;   Reactome:REACT_6901;   Reactome:REACT_6924;   Reactome:REACT_6934;   Reactome:REACT_6940;   Reactome:REACT_6951;   Reactome:REACT_77527;   Reactome:REACT_78454;   Reactome:REACT_78761;   Reactome:REACT_80639;   Reactome:REACT_80964;   Reactome:REACT_81206;   Reactome:REACT_81516;   Reactome:REACT_81850;   Reactome:REACT_82541;   Reactome:REACT_82595;   Reactome:REACT_83238;   Reactome:REACT_83320;   Reactome:REACT_83479;   Reactome:REACT_84153;   Reactome:REACT_84233;   Reactome:REACT_84451;   Reactome:REACT_84602;   Reactome:REACT_84963;   Reactome:REACT_84978;   Reactome:REACT_84983;   Reactome:REACT_85895;   Reactome:REACT_86311;   Reactome:REACT_87254;   Reactome:REACT_87301;   Reactome:REACT_90065;   Reactome:REACT_90294;   Reactome:REACT_90795;   Reactome:REACT_91303;   Reactome:REACT_91595;   Reactome:REACT_93284;   Reactome:REACT_93519;   Reactome:REACT_94912;   Reactome:REACT_95536;   Reactome:REACT_96679;   Reactome:REACT_98265;   Reactome:REACT_99018;   Wikipedia:Receptor-mediated_endocytosis

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receptor-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adrb2 adrenoceptor beta 2, surface GBrowse link ISO 18 58,174,958 58,177,000 RGD:1624291 RGD
G Adrb2 adrenoceptor beta 2, surface GBrowse link ISS 18 58,174,958 58,177,000 RGD:1600115 HGNC
G Adrb3 adrenoceptor beta 3 GBrowse link NOT ISO 16 69,163,620 69,166,384 RGD:1624291 RGD
G Apoe apolipoprotein E GBrowse link ISO 1 79,003,634 79,006,387 RGD:1624291 RGD
G Apoe apolipoprotein E GBrowse link IEA 1 79,003,634 79,006,387 RGD:1600115 ENSEMBL
G Arhgap27 Rho GTPase activating protein 27 GBrowse link IMP 10 92,522,546 92,551,340 RGD:1302833 RGD
G Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide GBrowse link IDA 7 1,376,552 1,383,228 RGD:629531 RGD
G Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) GBrowse link ISO 5 142,174,441 142,201,120 RGD:1624291 RGD
G Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) GBrowse link IEA 5 142,174,441 142,201,120 RGD:1600115 ENSEMBL
G Clec9a C-type lectin domain family 9, member A GBrowse link ISO 4 166,683,644 166,698,701 RGD:1624291 RGD
G Clec9a C-type lectin domain family 9, member A GBrowse link ISS 4 166,683,644 166,698,701 RGD:1600115 UniProtKB
G Clec9a C-type lectin domain family 9, member A GBrowse link ISO 4 166,683,644 166,698,701 RGD:1624291 RGD
G Clec9a C-type lectin domain family 9, member A GBrowse link ISO 4 166,683,644 166,698,701 RGD:1624291 RGD
G Cln3 ceroid-lipofuscinosis, neuronal 3 GBrowse link ISO 1 185,713,096 185,724,375 RGD:1624291 RGD
G Cln3 ceroid-lipofuscinosis, neuronal 3 GBrowse link ISS 1 185,713,096 185,724,375 RGD:1600115 UniProtKB
G Cltc clathrin, heavy chain (Hc) GBrowse link ISO 10 74,976,825 75,032,529 RGD:1624291 RGD
G Cltc clathrin, heavy chain (Hc) GBrowse link IMP 10 74,976,825 75,032,529 UniProtKB
G Cttn cortactin GBrowse link IDA 1 204,865,768 204,901,221 RGD:727733 RGD
G Cubn cubilin (intrinsic factor-cobalamin receptor) GBrowse link IDA 17 87,545,893 87,772,079 RGD:628443 RGD
G Cubn cubilin (intrinsic factor-cobalamin receptor) GBrowse link ISO 17 87,545,893 87,772,079 RGD:1624291 RGD
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link ISO 2 55,714,874 55,736,370 RGD:1624291 RGD
G Dnm1 dynamin 1 GBrowse link IMP 3 11,434,778 11,478,452 RGD:727371 RGD
G Dnm1 dynamin 1 GBrowse link ISO 3 11,434,778 11,478,452 RGD:1624291 RGD
G Dnm2 dynamin 2 GBrowse link IDA 8 20,527,130 20,610,749 RGD:728683 RGD
G Fcgr1a Fc fragment of IgG, high affinity Ia, receptor (CD64) GBrowse link ISO 2 191,095,026 191,103,942 RGD:1624291 RGD
G Hip1r huntingtin interacting protein 1 related GBrowse link ISO 12 33,714,225 33,742,792 RGD:1624291 RGD
G Hip1r huntingtin interacting protein 1 related GBrowse link ISO 12 33,714,225 33,742,792 RGD:1624291 RGD
G Hip1r huntingtin interacting protein 1 related GBrowse link IEA 12 33,714,225 33,742,792 RGD:1600115 ENSEMBL
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 GBrowse link ISO 3 87,108,483 87,275,069 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Lrp1 low density lipoprotein receptor-related protein 1 GBrowse link ISO 7 67,520,575 67,601,549 RGD:1624291 RGD
G Lrp1 low density lipoprotein receptor-related protein 1 GBrowse link IMP 7 67,520,575 67,601,549 RGD:2298533 RGD
G Lrp2 low density lipoprotein receptor-related protein 2 GBrowse link IDA 3 51,563,764 51,724,478 RGD:628443 RGD
G Lrp2 low density lipoprotein receptor-related protein 2 GBrowse link ISO 3 51,563,764 51,724,478 RGD:1624291 RGD
G Lrp2 low density lipoprotein receptor-related protein 2 GBrowse link IMP 3 51,563,764 51,724,478 BHF-UCL
G Mrc1 mannose receptor, C type 1 GBrowse link ISO 17 88,411,265 88,492,622 RGD:1624291 RGD
G Nlgn3 neuroligin 3 GBrowse link IDA X 89,376,193 89,398,665 BHF-UCL
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISO 1 146,754,085 146,834,197 RGD:1624291 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISO 1 146,754,085 146,834,197 RGD:1624291 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISS 1 146,754,085 146,834,197 RGD:1600115 UniProtKB
G Pikfyve phosphoinositide kinase, FYVE finger containing GBrowse link NOT ISO 9 63,798,743 63,890,905 RGD:1624291 RGD
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISO 3 42,121,966 42,250,869 RGD:1624291 RGD
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISO 3 42,121,966 42,250,869 RGD:1624291 RGD
G Pla2r1 phospholipase A2 receptor 1 GBrowse link ISS 3 42,121,966 42,250,869 RGD:1600115 UniProtKB
G Pld2 phospholipase D2 GBrowse link ISO 10 57,388,474 57,439,063 RGD:1624291 RGD
G Ppt1 palmitoyl-protein thioesterase 1 GBrowse link ISO 5 142,153,498 142,173,401 RGD:1624291 RGD
G Ppt1 palmitoyl-protein thioesterase 1 GBrowse link IEA 5 142,153,498 142,173,401 RGD:1600115 ENSEMBL
G Slc9a3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 GBrowse link IMP 1 29,930,908 29,973,686 RGD:1581379 RGD
G Snx17 sorting nexin 17 GBrowse link ISO 6 25,153,586 25,159,556 RGD:1624291 RGD
G Snx17 sorting nexin 17 GBrowse link IEA 6 25,153,586 25,159,556 RGD:1600115 ENSEMBL
G Tgfbr2 transforming growth factor, beta receptor II GBrowse link IDA 8 120,593,595 120,680,453 RGD:1579921 RGD
G Vldlr very low density lipoprotein receptor GBrowse link ISO 1 230,666,736 230,697,748 RGD:1624291 RGD
caveolin-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cav1 caveolin 1, caveolae protein GBrowse link ISO 4 42,956,102 42,989,057 RGD:1624291 RGD
G Cav1 caveolin 1, caveolae protein GBrowse link IEA 4 42,956,102 42,989,057 RGD:1600115 ENSEMBL
G Mapk1 mitogen activated protein kinase 1 GBrowse link TAS 11 85,968,732 86,030,387 UniProtKB
G Mapk3 mitogen activated protein kinase 3 GBrowse link TAS 1 185,935,044 185,941,245 UniProtKB
G Mlc1 megalencephalic leukoencephalopathy with subcortical cysts 1 GBrowse link IMP 7 127,265,491 127,288,102 RGD:2326037 UniProtKB
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 GBrowse link ISO 7 121,484,248 121,546,498 RGD:1624291 RGD
G Pacsin2 protein kinase C and casein kinase substrate in neurons 2 GBrowse link ISS 7 121,484,248 121,546,498 RGD:1600115 UniProtKB
clathrin-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Canx calnexin GBrowse link ISO 10 35,850,944 35,883,494 RGD:1624291 RGD
G Canx calnexin GBrowse link ISS 10 35,850,944 35,883,494 RGD:1600115 UniProtKB
G Fcho2 FCH domain only 2 GBrowse link ISO 2 29,349,477 29,451,434 RGD:1624291 RGD
G Fcho2 FCH domain only 2 GBrowse link ISO 2 29,349,477 29,451,434 RGD:1624291 RGD
G Fcho2 FCH domain only 2 GBrowse link ISS 2 29,349,477 29,451,434 RGD:1600115 UniProtKB
G-protein coupled receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Adm adrenomedullin GBrowse link ISO 1 168,380,255 168,382,426 RGD:1624291 RGD
G Adm adrenomedullin GBrowse link IEA 1 168,380,255 168,382,426 RGD:1600115 ENSEMBL
G Arrb1 arrestin, beta 1 GBrowse link ISO 1 156,871,564 156,937,540 RGD:1624291 RGD
G Arrb1 arrestin, beta 1 GBrowse link ISO 1 156,871,564 156,937,540 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link ISO 10 57,244,071 57,284,166 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link ISO 10 57,244,071 57,284,166 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link IEA 10 57,244,071 57,284,166 RGD:1600115 ENSEMBL
G Calca calcitonin-related polypeptide alpha GBrowse link ISO 1 172,686,168 172,691,061 RGD:1624291 RGD
G Drd2 dopamine receptor D2 GBrowse link IDA 8 52,641,160 52,707,749 RGD:1581465 RGD
G Drd3 dopamine receptor D3 GBrowse link IDA 11 58,446,901 58,520,589 RGD:1581465 RGD
G Drd3 dopamine receptor D3 GBrowse link ISO 11 58,446,901 58,520,589 RGD:1624291 RGD
G Grk4 G protein-coupled receptor kinase 4 GBrowse link IMP 14 81,648,003 81,722,480 RGD:1304268 RGD
G Gtf2h2 general transcription factor IIH, polypeptide 2 GBrowse link ISO 2 31,284,753 31,312,475 RGD:1624291 RGD
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled GBrowse link ISO 8 86,700,088 86,701,248 RGD:1624291 RGD
G Htr1b 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled GBrowse link IEA 8 86,700,088 86,701,248 RGD:1600115 ENSEMBL
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link ISO 9 84,840,026 84,852,984 RGD:1624291 RGD
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link ISO 9 84,840,026 84,852,984 RGD:1624291 RGD
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link IEA 9 84,840,026 84,852,984 RGD:1600115 ENSEMBL
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link IEA 9 84,840,026 84,852,984 RGD:1600115 ENSEMBL
G Htr2b 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled GBrowse link ISS 9 84,840,026 84,852,984 RGD:1600115 UniProtKB
G Pld2 phospholipase D2 GBrowse link ISO 10 57,388,474 57,439,063 RGD:1624291 RGD
negative regulation of receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Atxn2 ataxin 2 GBrowse link IEA 12 35,962,308 36,009,114 RGD:1600115 ENSEMBL
G Atxn2 ataxin 2 GBrowse link ISO 12 35,962,308 36,009,114 RGD:1624291 RGD
G Dlg4 discs, large homolog 4 (Drosophila) GBrowse link IDA 10 56,864,459 56,890,626 UniProtKB
G Mtmr2 myotubularin related protein 2 GBrowse link IMP 8 10,556,644 10,606,844 BHF-UCL
negative regulation of receptor-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Apoc1 apolipoprotein C-I GBrowse link ISO 1 78,996,677 78,999,960 RGD:1624291 RGD
G Apoc2 apolipoprotein C-II GBrowse link ISO 1 78,979,034 78,984,002 RGD:1624291 RGD
G Apoc2 apolipoprotein C-II GBrowse link IEA 1 78,979,034 78,984,002 RGD:1600115 ENSEMBL
G Apoc3 apolipoprotein C-III ISO RGD:1624291 RGD
G Apoc3 apolipoprotein C-III IEA RGD:1600115 ENSEMBL
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISO 1 146,754,085 146,834,197 RGD:1624291 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link IEA 1 146,754,085 146,834,197 RGD:1600115 ENSEMBL
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 GBrowse link ISO 12 27,497,545 27,525,385 RGD:1624291 RGD
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 GBrowse link IEA 12 27,497,545 27,525,385 RGD:1600115 ENSEMBL
positive regulation of clathrin-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Dab2 disabled 2, mitogen-responsive phosphoprotein GBrowse link ISO 2 55,714,874 55,736,370 RGD:1624291 RGD
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link IEA 7 26,429,923 26,483,533 RGD:1600115 ENSEMBL
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link ISO 7 26,429,923 26,483,533 RGD:1624291 RGD
G Wasl Wiskott-Aldrich syndrome-like GBrowse link IDA 4 51,063,710 51,092,848 BHF-UCL
positive regulation of receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ahi1 Abelson helper integration site 1 GBrowse link ISO 1 16,332,801 16,454,055 RGD:1624291 RGD
G Ahi1 Abelson helper integration site 1 GBrowse link ISS 1 16,332,801 16,454,055 RGD:1600115 UniProtKB
G Angpt1 angiopoietin 1 GBrowse link ISO 7 78,195,504 78,451,471 RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link IMP 10 57,244,071 57,284,166 RGD:5510008 RGD
G Atad1 ATPase family, AAA domain containing 1 GBrowse link ISO 1 236,682,640 236,726,705 RGD:1624291 RGD
G Atad1 ATPase family, AAA domain containing 1 GBrowse link ISS 1 236,682,640 236,726,705 RGD:1600115 UniProtKB
G Drd2 dopamine receptor D2 GBrowse link IMP 8 52,641,160 52,707,749 RGD:2311559 RGD
G Gh1 growth hormone 1 GBrowse link NOT ISO 10 95,692,240 95,694,117 RGD:1624291 RGD
G Grem1 gremlin 1 GBrowse link ISO 3 99,597,201 99,608,935 RGD:1624291 RGD
G Grem1 gremlin 1 GBrowse link IEA 3 99,597,201 99,608,935 RGD:1600115 ENSEMBL
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 GBrowse link IEA 4 9,909,448 11,441,301 RGD:1600115 ENSEMBL
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 GBrowse link ISO 4 9,909,448 11,441,301 RGD:1624291 RGD
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 GBrowse link ISS 4 9,909,448 11,441,301 RGD:1600115 UniProtKB
G Ntf3 neurotrophin 3 GBrowse link IEA 4 162,435,781 162,506,961 RGD:1600115 ENSEMBL
G Ntf3 neurotrophin 3 GBrowse link ISO 4 162,435,781 162,506,961 RGD:1624291 RGD
G Pcsk9 proprotein convertase subtilisin/kexin type 9 GBrowse link ISO 5 127,501,476 127,524,289 RGD:1624291 RGD
G Pcsk9 proprotein convertase subtilisin/kexin type 9 GBrowse link IEA 5 127,501,476 127,524,289 RGD:1600115 ENSEMBL
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link IEA 7 26,429,923 26,483,533 RGD:1600115 ENSEMBL
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link ISO 7 26,429,923 26,483,533 RGD:1624291 RGD
G Sele selectin E GBrowse link ISO 13 79,813,455 79,822,845 RGD:1624291 RGD
G Sele selectin E GBrowse link IEA 13 79,813,455 79,822,845 RGD:1600115 ENSEMBL
G Sfrp4 secreted frizzled-related protein 4 GBrowse link ISO 17 53,121,425 53,131,507 RGD:1624291 RGD
G Sfrp4 secreted frizzled-related protein 4 GBrowse link IEA 17 53,121,425 53,131,507 RGD:1600115 ENSEMBL
G Synj2bp synaptojanin 2 binding protein GBrowse link IEA 6 105,352,102 105,389,779 RGD:1600115 ENSEMBL
G Vegfa vascular endothelial growth factor A GBrowse link ISO 9 10,520,730 10,536,071 RGD:1624291 RGD
G Vegfa vascular endothelial growth factor A GBrowse link IEA 9 10,520,730 10,536,071 RGD:1600115 ENSEMBL
G Wnt3a wingless-type MMTV integration site family, member 3A GBrowse link ISO 10 45,553,682 45,594,983 RGD:1624291 RGD
positive regulation of receptor-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link IEA 4 186,922,060 187,069,288 RGD:1600115 ENSEMBL
G Bicd1 bicaudal D homolog 1 (Drosophila) GBrowse link ISO 4 186,922,060 187,069,288 RGD:1624291 RGD
G Hip1 huntingtin interacting protein 1 GBrowse link ISO 12 22,287,861 22,422,163 RGD:1624291 RGD
G Hip1 huntingtin interacting protein 1 GBrowse link ISO 12 22,287,861 22,422,163 RGD:1624291 RGD
G Hip1 huntingtin interacting protein 1 GBrowse link ISO 12 22,287,861 22,422,163 RGD:1624291 RGD
G Hip1 huntingtin interacting protein 1 GBrowse link IEA 12 22,287,861 22,422,163 RGD:1600115 ENSEMBL
G Hip1 huntingtin interacting protein 1 GBrowse link IEA 12 22,287,861 22,422,163 RGD:1600115 ENSEMBL
G Hnrnpk heterogeneous nuclear ribonucleoprotein K GBrowse link ISO 17 12,196,630 12,205,720 RGD:1624291 RGD
G Kif3a kinesin family member 3a GBrowse link IDA 10 39,029,351 39,062,570 RGD:1581596 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Pld2 phospholipase D2 GBrowse link IMP 10 57,388,474 57,439,063 RGD:2299909 RGD
G Ppt1 palmitoyl-protein thioesterase 1 GBrowse link ISO 5 142,153,498 142,173,401 RGD:1624291 RGD
G Ppt1 palmitoyl-protein thioesterase 1 GBrowse link ISS 5 142,153,498 142,173,401 UniProtKB
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link ISO 12 20,931,996 20,942,374 RGD:1624291 RGD
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IEA 12 20,931,996 20,942,374 RGD:1600115 ENSEMBL
G Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 GBrowse link IMP 12 20,931,996 20,942,374 BHF-UCL
G Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 GBrowse link ISO 5 123,696,703 123,897,989 RGD:1624291 RGD
G Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 GBrowse link ISS 5 123,696,703 123,897,989 UniProtKB
G Syne1 spectrin repeat containing, nuclear envelope 1 GBrowse link IMP 1 35,803,552 36,269,628 RGD:2314546 RGD
G Synj1 synaptojanin 1 GBrowse link IMP 11 30,921,834 30,998,609 RGD:2312450 RGD
G Vtn vitronectin GBrowse link ISO 10 64,609,242 64,612,322 RGD:1624291 RGD
G Vtn vitronectin GBrowse link IEA 10 64,609,242 64,612,322 RGD:1600115 ENSEMBL
receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ache acetylcholinesterase ISO RGD:1624291 RGD
G Adm adrenomedullin GBrowse link ISO 1 168,380,255 168,382,426 RGD:1624291 RGD
G Adm adrenomedullin GBrowse link ISO 1 168,380,255 168,382,426 RGD:1624291 RGD
G Adm adrenomedullin GBrowse link ISO 1 168,380,255 168,382,426 RGD:1624291 RGD
G Adrbk1 adrenergic, beta, receptor kinase 1 GBrowse link ISO 1 206,873,002 206,892,868 RGD:1624291 RGD
G Adrbk1 adrenergic, beta, receptor kinase 1 GBrowse link IEA 1 206,873,002 206,892,868 RGD:1600115 ENSEMBL
G Adrbk2 adrenergic, beta, receptor kinase 2 ISO RGD:1624291 RGD
G Arrb2 arrestin, beta 2 GBrowse link ISO 10 57,244,071 57,284,166 RGD:1624291 RGD
G Calca calcitonin-related polypeptide alpha GBrowse link ISO 1 172,686,168 172,691,061 RGD:1624291 RGD
G Calcr calcitonin receptor GBrowse link ISO 4 28,486,176 28,561,296 RGD:1624291 RGD
G Calcrl calcitonin receptor-like GBrowse link ISO 3 67,553,022 67,646,877 RGD:1624291 RGD
G Calcrl calcitonin receptor-like GBrowse link IEA 3 67,553,022 67,646,877 RGD:1600115 ENSEMBL
G Cltc clathrin, heavy chain (Hc) GBrowse link ISO 10 74,976,825 75,032,529 RGD:1624291 RGD
G Cltc clathrin, heavy chain (Hc) GBrowse link IEA 10 74,976,825 75,032,529 RGD:1600115 ENSEMBL
G Cntn2 contactin 2 (axonal) GBrowse link ISO 13 45,399,915 45,428,789 RGD:1624291 RGD
G Cntn2 contactin 2 (axonal) GBrowse link IEA 13 45,399,915 45,428,789 RGD:1600115 ENSEMBL
G Cxcr1 chemokine (C-X-C motif) receptor 1 GBrowse link ISO 9 73,510,488 73,511,537 RGD:1624291 RGD
G Cxcr1 chemokine (C-X-C motif) receptor 1 GBrowse link IEA 9 73,510,488 73,511,537 RGD:1600115 ENSEMBL
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link ISO 9 73,470,943 73,477,315 RGD:1624291 RGD
G Cxcr2 chemokine (C-X-C motif) receptor 2 GBrowse link IEA 9 73,470,943 73,477,315 RGD:1600115 ENSEMBL
G Dnm1 dynamin 1 GBrowse link IMP 3 11,434,778 11,478,452 UniProtKB
G Dnm2 dynamin 2 GBrowse link ISO 8 20,527,130 20,610,749 RGD:1624291 RGD
G Ghr growth hormone receptor GBrowse link NOT ISO 2 52,496,517 52,658,066 RGD:1624291 RGD
G Ghr growth hormone receptor GBrowse link ISO 2 52,496,517 52,658,066 RGD:1624291 RGD
G Grb2 growth factor receptor bound protein 2 GBrowse link ISO 10 105,722,014 105,818,649 RGD:1624291 RGD
G Grb2 growth factor receptor bound protein 2 GBrowse link IEA 10 105,722,014 105,818,649 RGD:1600115 ENSEMBL
G Gria1 glutamate receptor, ionotropic, AMPA 1 GBrowse link ISO 10 42,613,359 42,616,610 RGD:1624291 RGD
G Gria1 glutamate receptor, ionotropic, AMPA 1 GBrowse link IDA 10 42,613,359 42,616,610 UniProtKB
G Gria2 glutamate receptor, ionotropic, AMPA 2 GBrowse link IDA 2 172,265,155 172,385,285 UniProtKB
G Grk4 G protein-coupled receptor kinase 4 GBrowse link ISO 14 81,648,003 81,722,480 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Mmp13 matrix metallopeptidase 13 GBrowse link IGI 8 4,158,887 4,169,166 RGD:2298533 RGD
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase GBrowse link ISO 8 77,252,500 77,337,402 RGD:1624291 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link ISO 1 146,754,085 146,834,197 RGD:1624291 RGD
G Picalm phosphatidylinositol binding clathrin assembly protein GBrowse link IEA 1 146,754,085 146,834,197 RGD:1600115 ENSEMBL
G Rab31 RAB31, member RAS oncogene family GBrowse link ISO 9 104,408,546 104,543,084 RGD:1624291 RGD
G Rab31 RAB31, member RAS oncogene family GBrowse link ISS 9 104,408,546 104,543,084 RGD:1600115 UniProtKB
G Ramp1 receptor (G protein-coupled) activity modifying protein 1 GBrowse link ISO 9 90,402,493 90,450,038 RGD:1624291 RGD
G Ramp1 receptor (G protein-coupled) activity modifying protein 1 GBrowse link IDA 9 90,402,493 90,450,038 UniProtKB
G Ramp2 receptor (G protein-coupled) activity modifying protein 2 GBrowse link ISO 10 90,275,463 90,277,242 RGD:1624291 RGD
G Ramp2 receptor (G protein-coupled) activity modifying protein 2 GBrowse link ISO 10 90,275,463 90,277,242 RGD:1624291 RGD
G Ramp2 receptor (G protein-coupled) activity modifying protein 2 GBrowse link ISO 10 90,275,463 90,277,242 RGD:1624291 RGD
G Ramp2 receptor (G protein-coupled) activity modifying protein 2 GBrowse link IDA 10 90,275,463 90,277,242 UniProtKB
G Ramp3 receptor (G protein-coupled) activity modifying protein 3 GBrowse link ISO 14 87,417,290 87,434,789 RGD:1624291 RGD
G Ramp3 receptor (G protein-coupled) activity modifying protein 3 GBrowse link ISO 14 87,417,290 87,434,789 RGD:1624291 RGD
G Ramp3 receptor (G protein-coupled) activity modifying protein 3 GBrowse link IEA 14 87,417,290 87,434,789 RGD:1600115 ENSEMBL
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link ISO 4 89,613,731 89,722,807 RGD:1624291 RGD
G Snca synuclein, alpha (non A4 component of amyloid precursor) GBrowse link IEA 4 89,613,731 89,722,807 RGD:1600115 ENSEMBL
G Ulk1 Unc-51 like kinase 1 (C. elegans) GBrowse link ISO 12 45,996,251 46,022,505 RGD:1624291 RGD
G Ulk1 Unc-51 like kinase 1 (C. elegans) GBrowse link IEA 12 45,996,251 46,022,505 RGD:1600115 ENSEMBL
receptor internalization involved in canonical Wnt receptor signaling pathway term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cav1 caveolin 1, caveolae protein GBrowse link ISO 4 42,956,102 42,989,057 RGD:1624291 RGD
G Cav1 caveolin 1, caveolae protein GBrowse link IEA 4 42,956,102 42,989,057 RGD:1600115 ENSEMBL
G Rab5a RAB5A, member RAS oncogene family GBrowse link ISO 9 1,492,864 1,516,405 RGD:1624291 RGD
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link IEA 7 26,429,923 26,483,533 RGD:1600115 ENSEMBL
G Scyl2 SCY1-like 2 (S. cerevisiae) GBrowse link ISO 7 26,429,923 26,483,533 RGD:1624291 RGD
receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 GBrowse link ISO 5 153,504,535 153,527,523 RGD:1624291 RGD
G Lrp6 low density lipoprotein receptor-related protein 6 GBrowse link ISO 4 171,337,114 171,444,932 RGD:1624291 RGD
G Lrp6 low density lipoprotein receptor-related protein 6 GBrowse link IBA 4 171,337,114 171,444,932 RGD:1600115 RefGenome
regulation of clathrin-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Aak1 AP2 associated kinase 1 GBrowse link IEA 4 121,008,188 121,153,112 RGD:1600115 ENSEMBL
G Aak1 AP2 associated kinase 1 GBrowse link IDA 4 121,008,188 121,153,112 UniProtKB
G Tnk2 tyrosine kinase, non-receptor, 2 GBrowse link ISO 11 69,927,509 69,966,854 RGD:1624291 RGD
G Tnk2 tyrosine kinase, non-receptor, 2 GBrowse link IEA 11 69,927,509 69,966,854 RGD:1600115 ENSEMBL
regulation of receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Dkk1 dickkopf 1 homolog (Xenopus laevis) GBrowse link ISO 1 234,392,743 234,396,426 RGD:1624291 RGD
G Rspo1 R-spondin 1 GBrowse link IEA 5 144,332,302 144,353,646 RGD:1600115 ENSEMBL
G Rspo1 R-spondin 1 GBrowse link ISO 5 144,332,302 144,353,646 RGD:1624291 RGD
G Sh3gl2 SH3-domain GRB2-like 2 GBrowse link ISO 5 104,129,280 104,308,317 RGD:1624291 RGD
G Sh3gl2 SH3-domain GRB2-like 2 GBrowse link IEA 5 104,129,280 104,308,317 RGD:1600115 ENSEMBL
regulation of receptor-mediated endocytosis term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cd2ap CD2-associated protein GBrowse link IDA 9 13,827,015 13,888,338 RGD:1302417 RGD
G Prkca protein kinase C, alpha GBrowse link IMP 10 97,367,196 97,638,910 RGD:1601478 RGD
regulation of signal transduction by receptor internalization term browser
Symbol Object Name GBrowse Qualifiers Evidence Chr Start Stop Reference Source
G Cav3 caveolin 3 GBrowse link IEA 4 148,294,428 148,310,380 RGD:1600115 ENSEMBL
G Cav3 caveolin 3 GBrowse link ISO 4 148,294,428 148,310,380 RGD:1624291 RGD
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 135967
    establishment of localization 9555
      transport 9361
        vesicle-mediated transport 1751
          endocytosis 696
            receptor-mediated endocytosis 224
              caveolin-mediated endocytosis + 7
              clathrin-mediated endocytosis + 13
              negative regulation of receptor-mediated endocytosis + 13
              positive regulation of receptor-mediated endocytosis + 53
              receptor internalization + 114
              receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 5
              regulation of receptor-mediated endocytosis + 77
              viral entry into host cell via receptor-mediated endocytosis + 0
Path 2
Term Annotations click to browse term
  biological_process 135967
    localization 13276
      establishment of localization 9555
        transport 9361
          vesicle-mediated transport 1751
            endocytosis 696
              receptor-mediated endocytosis 224
                caveolin-mediated endocytosis + 7
                clathrin-mediated endocytosis + 13
                negative regulation of receptor-mediated endocytosis + 13
                positive regulation of receptor-mediated endocytosis + 53
                receptor internalization + 114
                receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport 5
                regulation of receptor-mediated endocytosis + 77
                viral entry into host cell via receptor-mediated endocytosis + 0
paths to the root

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