fatty acid biosynthetic process - Ontology Report

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Term:	fatty acid biosynthetic process	go back to main search page
Accession:	GO:0006633	browse the term
Definition:	The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
Synonyms:	exact_synonym:	fatty acid anabolism; fatty acid biosynthesis; fatty acid formation; fatty acid synthesis
	alt_id:	GO:0000037
	xref_analog:	MetaCyc:FASYN-INITIAL-PWY; MetaCyc:PWY-4381; MetaCyc:PWY-5156; Wikipedia:Fatty_acid_synthesis

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fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acaca	acetyl-CoA carboxylase alpha		IDA	10	72,483,772	72,677,134	RGD:2317316	RGD
G	Acaca	acetyl-CoA carboxylase alpha		ISO	10	72,483,772	72,677,134	RGD:1624291	RGD
G	Acaca	acetyl-CoA carboxylase alpha		IEA	10	72,483,772	72,677,134	RGD:1600115	ENSEMBL
G	Acacb	acetyl-CoA carboxylase beta		ISO	12	43,388,679	43,492,993	RGD:1624291	RGD
G	Acacb	acetyl-CoA carboxylase beta		IEA	12	43,388,679	43,492,993	RGD:1600115	InterPro
G	Acly	ATP citrate lyase		IDA	10	89,420,934	89,471,398	RGD:2317316	RGD
G	Acsf3	acyl-CoA synthetase family member 3		IEA	19	53,066,291	53,106,673	RGD:1600115	ENSEMBL
G	Acsf3	acyl-CoA synthetase family member 3		ISO	19	53,066,291	53,106,673	RGD:1624291	RGD
G	Acsl3	acyl-CoA synthetase long-chain family member 3		IDA	9	78,083,239	78,106,933	RGD:70280	RGD
G	Acsm3	acyl-CoA synthetase medium-chain family member 3		ISO	1	178,054,386	178,081,751	RGD:1624291	RGD
G	Acsm3	acyl-CoA synthetase medium-chain family member 3		IEA	1	178,054,386	178,081,751	RGD:1600115	ENSEMBL
G	Agmo	alkylglycerol monooxygenase		IEA	6	56,042,873	56,380,045	RGD:1600115	InterPro
G	Brca1	breast cancer 1, early onset		IEA	10	90,513,630	90,572,676	RGD:1600115	UniProtKB
G	Cbr4	carbonyl reductase 4		IEA	16	31,943,125	31,957,556	RGD:1600115	UniPathway
G	Ch25h	cholesterol 25-hydroxylase		IEA	1	238,457,017	238,458,335	RGD:1600115	InterPro
G	Degs1	delta(4)-desaturase, sphingolipid 1		IEA	13	98,242,981	98,249,638	RGD:1600115	UniProtKB
G	Degs2	delta(4)-desaturase, sphingolipid 2		IEA	6	133,021,596	133,037,633	RGD:1600115	InterPro
G	Fa2h	fatty acid 2-hydroxylase		IEA	19	41,268,120	41,319,682	RGD:1600115	UniProtKB
G	Fads3	fatty acid desaturase 3		IEA	1	212,489,224	212,506,444	RGD:1600115	UniProtKB
G	Fasn	fatty acid synthase		IMP				RGD:2317317	RGD
G	Hnf1a	HNF1 homeobox A		ISO	12	42,919,574	42,945,670	RGD:1624291	RGD
G	Hnf1a	HNF1 homeobox A		IEA	12	42,919,574	42,945,670	RGD:1600115	ENSEMBL
G	Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12		IEA	3	78,436,634	78,559,707	RGD:1600115	UniPathway
G	Hsd17b8	hydroxysteroid (17-beta) dehydrogenase 8		IEA	20	4,964,860	4,966,855	RGD:1600115	UniPathway
G	Lipc	lipase, hepatic		ISO	8	75,323,442	75,450,353	RGD:1624291	RGD
G	Lipc	lipase, hepatic		IEA	8	75,323,442	75,450,353	RGD:1600115	ENSEMBL
G	LOC100912469	acyl-CoA desaturase 2-like		IEA				RGD:1600115	InterPro
G	LOC683884	similar to Acyl carrier protein, mitochondrial precursor (ACP) (NADH-ubiquinone oxidoreductase 9.6 kDa subunit) (CI-SDAP)		IEA				RGD:1600115	UniProtKB
G	LOC691221	similar to CG1998-PA		IEA	10	43,678,705	43,703,616	RGD:1600115	InterPro
G	Lpl	lipoprotein lipase		ISO	16	22,533,105	22,556,905	RGD:1624291	RGD
G	Mcat	malonyl CoA:ACP acyltransferase (mitochondrial)		ISO	7	121,363,760	121,374,689	RGD:1624291	RGD
G	Mecr	mitochondrial trans-2-enoyl-CoA reductase		IEA	5	150,700,130	150,725,219	RGD:1600115	UniProtKB
G	Mgll	monoglyceride lipase		IEA	4	122,822,493	122,922,892	RGD:1600115	UniProtKB
G	Mlycd	malonyl-CoA decarboxylase		ISO	19	49,637,193	49,653,016	RGD:1624291	RGD
G	Mlycd	malonyl-CoA decarboxylase		IEA	19	49,637,193	49,653,016	RGD:1600115	ENSEMBL
G	Msmo1	methylsterol monooxygenase 1		IEA	16	26,698,324	26,716,247	RGD:1600115	InterPro
G	Olah	oleoyl-ACP hydrolase		IEA	17	85,996,338	86,021,192	RGD:1600115	UniProtKB
G	Pecr	peroxisomal trans-2-enoyl-CoA reductase		IEA	9	71,414,826	71,443,719	RGD:1600115	UniPathway
G	Pla2g1b	phospholipase A2, group IB, pancreas		ISO	12	42,405,475	42,415,189	RGD:1624291	RGD
G	Pla2g1b	phospholipase A2, group IB, pancreas		IDA	12	42,405,475	42,415,189		BHF-UCL
G	Prkaa1	protein kinase, AMP-activated, alpha 1 catalytic subunit		IEA	2	54,327,821	54,360,462	RGD:1600115	UniProtKB
G	Prkaa2	protein kinase, AMP-activated, alpha 2 catalytic subunit		IEA	5	126,007,672	126,074,012	RGD:1600115	UniProtKB
G	Prkab1	protein kinase, AMP-activated, beta 1 non-catalytic subunit		IEA	12	41,840,866	41,851,241	RGD:1600115	UniProtKB
G	Prkab2	protein kinase, AMP-activated, beta 2 non-catalytic subunit		IEA	2	192,498,430	192,510,624	RGD:1600115	UniProtKB
G	Prkag1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit		IEA	7	137,582,341	137,599,762	RGD:1600115	UniProtKB
G	RGD1311224	similar to fatty acid desaturase 2; linoleoyl-CoA desaturase (delta-6-desaturase)-like 2; delta-6 fatty acid desaturase		IEA	3	68,696,307	68,735,967	RGD:1600115	InterPro
G	RGD1564463	similar to Mdes protein		IEA	13	96,840,774	96,847,914	RGD:1600115	InterPro
G	Sc5d	sterol-C5-desaturase		IEA	8	45,229,976	45,238,924	RGD:1600115	InterPro
G	Scd	stearoyl-CoA desaturase (delta-9-desaturase)		TAS	1	249,358,105	249,371,164	RGD:1580018	RGD
G	Scd1	stearoyl-Coenzyme A desaturase 1		TAS	1	249,458,860	249,471,460	RGD:1304415	RGD
G	Scd1	stearoyl-Coenzyme A desaturase 1		ISO	1	249,458,860	249,471,460	RGD:1624291	RGD
G	Scd4	stearoyl-coenzyme A desaturase 4		ISO	1	249,392,727	249,404,075	RGD:1624291	RGD
G	Scd4	stearoyl-coenzyme A desaturase 4		IEA	1	249,392,727	249,404,075	RGD:1600115	ENSEMBL
2-oxobutyrate biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Thnsl2	threonine synthase-like 2 (S. cerevisiae)		ISO	4	104,329,517	104,348,465	RGD:1624291	RGD
G	Thnsl2	threonine synthase-like 2 (S. cerevisiae)		IEA	4	104,329,517	104,348,465	RGD:1600115	ENSEMBL
cyclooxygenase pathway
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Ptgs1	prostaglandin-endoperoxide synthase 1		ISO	3	15,343,832	15,365,412	RGD:1624291	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1		IEA	3	15,343,832	15,365,412	RGD:1600115	ENSEMBL
G	Ptgs2	prostaglandin-endoperoxide synthase 2		ISO	13	64,427,288	64,432,978	RGD:1624291	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		ISO	13	64,427,288	64,432,978	RGD:1624291	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		ISO	13	64,427,288	64,432,978	RGD:1624291	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		ISS	13	64,427,288	64,432,978	RGD:1600115	UniProtKB
G	Sphk1	sphingosine kinase 1		IDA	10	106,641,509	106,645,579	RGD:2311353	RGD
fatty acid elongation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl6	ELOVL fatty acid elongase 6		ISO	2	226,946,573	227,054,321	RGD:1624291	RGD
G	Tecr	trans-2,3-enoyl-CoA reductase		ISO	19	26,232,602	26,259,289	RGD:1624291	RGD
G	Tecr	trans-2,3-enoyl-CoA reductase		ISS	19	26,232,602	26,259,289	RGD:1600115	UniProtKB
fatty acid elongation, monounsaturated fatty acid
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl1	ELOVL fatty acid elongase 1		ISO	5	138,909,438	138,912,186	RGD:1624291	RGD
G	Elovl1	ELOVL fatty acid elongase 1		IEA	5	138,909,438	138,912,186	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISO	8	82,922,551	82,948,348	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISS	8	82,922,551	82,948,348	RGD:1600115	UniProtKB
G	Elovl6	ELOVL fatty acid elongase 6		IDA	2	226,946,573	227,054,321		UniProtKB
fatty acid elongation, polyunsaturated fatty acid
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		IEA	17	29,492,349	29,532,622	RGD:1600115	ENSEMBL
G	Elovl2	ELOVL fatty acid elongase 2		IEA	17	29,492,349	29,532,622	RGD:1600115	ENSEMBL
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISO	8	82,922,551	82,948,348	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISO	8	82,922,551	82,948,348	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		IDA	8	82,922,551	82,948,348		UniProtKB
G	Elovl7	ELOVL fatty acid elongase 7		ISO	2	39,568,590	39,596,055	RGD:1624291	RGD
G	Elovl7	ELOVL fatty acid elongase 7		IEA	2	39,568,590	39,596,055	RGD:1600115	ENSEMBL
fatty acid elongation, saturated fatty acid
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl1	ELOVL fatty acid elongase 1		ISO	5	138,909,438	138,912,186	RGD:1624291	RGD
G	Elovl1	ELOVL fatty acid elongase 1		ISO	5	138,909,438	138,912,186	RGD:1624291	RGD
G	Elovl1	ELOVL fatty acid elongase 1		IEA	5	138,909,438	138,912,186	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl4	ELOVL fatty acid elongase 4		IEA	8	88,855,155	88,881,703	RGD:1600115	ENSEMBL
G	Elovl4	ELOVL fatty acid elongase 4		ISO	8	88,855,155	88,881,703	RGD:1624291	RGD
G	Elovl6	ELOVL fatty acid elongase 6		ISO	2	226,946,573	227,054,321	RGD:1624291	RGD
G	Elovl6	ELOVL fatty acid elongase 6		IDA	2	226,946,573	227,054,321		UniProtKB
G	Elovl7	ELOVL fatty acid elongase 7		ISO	2	39,568,590	39,596,055	RGD:1624291	RGD
G	Elovl7	ELOVL fatty acid elongase 7		IEA	2	39,568,590	39,596,055	RGD:1600115	ENSEMBL
hepoxilin biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Alox15	arachidonate 15-lipoxygenase		IDA	10	57,185,939	57,194,388	RGD:5509794	RGD
leukotriene biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Alox12b	arachidonate 12-lipoxygenase, 12R type		IEA	10	55,917,373	55,926,321	RGD:1600115	UniProtKB
G	Alox15	arachidonate 15-lipoxygenase		IEA	10	57,185,939	57,194,388	RGD:1600115	UniProtKB
G	Alox15b	arachidonate 15-lipoxygenase, type B		IEA	10	55,951,005	55,960,265	RGD:1600115	UniProtKB
G	Alox5	arachidonate 5-lipoxygenase		TAS	4	152,610,283	152,657,891	RGD:632194	RGD
G	Alox5	arachidonate 5-lipoxygenase		ISO	4	152,610,283	152,657,891	RGD:1624291	RGD
G	Alox5	arachidonate 5-lipoxygenase		ISO	4	152,610,283	152,657,891	RGD:1624291	RGD
G	Alox5	arachidonate 5-lipoxygenase		ISO	4	152,610,283	152,657,891	RGD:1624291	RGD
G	Alox5	arachidonate 5-lipoxygenase		ISS	4	152,610,283	152,657,891	RGD:1600115	UniProtKB
G	Alox5ap	arachidonate 5-lipoxygenase activating protein		IDA	12	6,245,808	6,269,796	RGD:69749	RGD
G	Alox5ap	arachidonate 5-lipoxygenase activating protein		IDA	12	6,245,808	6,269,796	RGD:2313889	RGD
G	Alox5ap	arachidonate 5-lipoxygenase activating protein		ISO	12	6,245,808	6,269,796	RGD:1624291	RGD
G	Alox5ap	arachidonate 5-lipoxygenase activating protein		ISO	12	6,245,808	6,269,796	RGD:1624291	RGD
G	Alox5ap	arachidonate 5-lipoxygenase activating protein		ISO	12	6,245,808	6,269,796	RGD:1624291	RGD
G	Fcer1a	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide		ISO	13	89,429,982	89,436,507	RGD:1624291	RGD
G	Ggt1	gamma-glutamyltransferase 1		ISO				RGD:1624291	RGD
G	Ggt5	gamma-glutamyltransferase 5		ISO				RGD:1624291	RGD
G	Ggt5	gamma-glutamyltransferase 5		IEA				RGD:1600115	UniProtKB
G	Ighe	immunoglobulin heavy chain (epsilon polypeptide)		ISO				RGD:1624291	RGD
G	LOC684035	similar to arginyl aminopeptidase (aminopeptidase B)-like 1		IEA				RGD:1600115	InterPro
G	Lta4h	leukotriene A4 hydrolase		ISO	7	30,482,213	30,515,062	RGD:1624291	RGD
G	Lta4h	leukotriene A4 hydrolase		ISS	7	30,482,213	30,515,062	RGD:1600115	UniProtKB
G	Lta4h	leukotriene A4 hydrolase		IEA	7	30,482,213	30,515,062	RGD:1600115	ENSEMBL
G	Ltc4s	leukotriene C4 synthase		TAS	10	35,786,877	35,788,838	RGD:724432	RGD
G	Ltc4s	leukotriene C4 synthase		IDA	10	35,786,877	35,788,838	RGD:2302289	RGD
G	Mgst2	microsomal glutathione S-transferase 2		ISO	2	140,546,939	140,568,616	RGD:1624291	RGD
G	Mgst2	microsomal glutathione S-transferase 2		ISO	2	140,546,939	140,568,616	RGD:1624291	RGD
G	Npepo	aminopeptidase O		IEA	17	7,353,426	7,624,936	RGD:1600115	InterPro
G	Pla2g5	phospholipase A2, group V		IDA	5	157,619,703	157,640,971	RGD:2303037	RGD
G	Prg3	proteoglycan 3		IEA	3	68,219,693	68,225,298	RGD:1600115	ENSEMBL
G	Prg3	proteoglycan 3		ISO	3	68,219,693	68,225,298	RGD:1624291	RGD
G	Rnpep	arginyl aminopeptidase (aminopeptidase B)		IEA	13	48,267,923	48,286,295	RGD:1600115	InterPro
G	Syk	spleen tyrosine kinase		ISO	17	18,440,672	18,498,001	RGD:1624291	RGD
G	Syk	spleen tyrosine kinase		IEA	17	18,440,672	18,498,001	RGD:1600115	ENSEMBL
lipoate biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Lias	lipoic acid synthetase		ISO	14	45,575,334	45,592,514	RGD:1624291	RGD
G	Lipt2	lipoyl(octanoyl) transferase 2 (putative)		IEA	1	157,538,704	157,541,031	RGD:1600115	InterPro
long-chain fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl6	ELOVL fatty acid elongase 6		ISO	2	226,946,573	227,054,321	RGD:1624291	RGD
G	Elovl6	ELOVL fatty acid elongase 6		ISS	2	226,946,573	227,054,321	RGD:1600115	UniProtKB
G	Myo5a	myosin VA		ISO	8	79,909,224	80,027,290	RGD:1624291	RGD
G	Plp1	proteolipid protein 1		ISO	X	124,488,627	124,503,639	RGD:1624291	RGD
G	Plp1	proteolipid protein 1		IEA	X	124,488,627	124,503,639	RGD:1600115	ENSEMBL
G	Qk	quaking		ISO	1	44,922,562	45,025,572	RGD:1624291	RGD
medium-chain fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Oxsm	3-oxoacyl-ACP synthase, mitochondrial		ISO	15	10,761,610	10,765,356	RGD:1624291	RGD
G	Oxsm	3-oxoacyl-ACP synthase, mitochondrial		IEA	15	10,761,610	10,765,356	RGD:1600115	ENSEMBL
negative regulation of fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acadl	acyl-CoA dehydrogenase, long chain		ISO	9	65,613,130	65,651,775	RGD:1624291	RGD
G	Acadl	acyl-CoA dehydrogenase, long chain		IEA	9	65,613,130	65,651,775	RGD:1600115	ENSEMBL
G	Acadvl	acyl-CoA dehydrogenase, very long chain		ISO	10	56,856,233	56,861,380	RGD:1624291	RGD
G	Acadvl	acyl-CoA dehydrogenase, very long chain		IEA	10	56,856,233	56,861,380	RGD:1600115	ENSEMBL
G	Apoc1	apolipoprotein C-I		ISO	1	78,996,677	78,999,960	RGD:1624291	RGD
G	Apoc3	apolipoprotein C-III		ISO				RGD:1624291	RGD
G	Apoc3	apolipoprotein C-III		ISO				RGD:1624291	RGD
G	Apoc3	apolipoprotein C-III		IEA				RGD:1600115	ENSEMBL
G	Brca1	breast cancer 1, early onset		ISO	10	90,513,630	90,572,676	RGD:1624291	RGD
G	Brca1	breast cancer 1, early onset		ISS	10	90,513,630	90,572,676	RGD:1600115	UniProtKB
G	Insig1	insulin induced gene 1		ISO	4	2,577,468	2,585,682	RGD:1624291	RGD
G	Insig2	insulin induced gene 2		ISO	13	33,331,951	33,345,132	RGD:1624291	RGD
G	Insig2	insulin induced gene 2		IEA	13	33,331,951	33,345,132	RGD:1600115	ENSEMBL
G	Trib3	tribbles homolog 3 (Drosophila)		ISO	3	142,664,641	142,670,135	RGD:1624291	RGD
G	Trib3	tribbles homolog 3 (Drosophila)		IEA	3	142,664,641	142,670,135	RGD:1600115	ENSEMBL
G	Wdtc1	WD and tetratricopeptide repeats 1		ISO	5	151,784,746	151,834,368	RGD:1624291	RGD
G	Wdtc1	WD and tetratricopeptide repeats 1		IEA	5	151,784,746	151,834,368	RGD:1600115	ENSEMBL
negative regulation of prostaglandin biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Sirt1	sirtuin 1		IEA	20	25,675,302	25,686,494	RGD:1600115	ENSEMBL
G	Sirt1	sirtuin 1		ISO	20	25,675,302	25,686,494	RGD:1624291	RGD
positive regulation of fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		ISO	19	54,738,556	54,750,349	RGD:1624291	RGD
G	Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)		IEA	19	54,738,556	54,750,349	RGD:1600115	ENSEMBL
G	Apoa4	apolipoprotein A-IV		ISO	8	49,233,142	49,233,431	RGD:1624291	RGD
G	Apoa5	apolipoprotein A-V		ISO	8	49,253,538	49,255,777	RGD:1624291	RGD
G	Apoa5	apolipoprotein A-V		IEA	8	49,253,538	49,255,777	RGD:1600115	ENSEMBL
G	Apoc2	apolipoprotein C-II		ISO	1	78,979,034	78,984,002	RGD:1624291	RGD
G	Apoc2	apolipoprotein C-II		IEA	1	78,979,034	78,984,002	RGD:1600115	ENSEMBL
G	Hnf4a	hepatocyte nuclear factor 4, alpha		IMP	3	154,459,863	154,482,825	RGD:1624995	RGD
G	Mid1ip1	MID1 interacting protein 1		ISO	X	24,205,679	24,207,860	RGD:1624291	RGD
G	Mid1ip1	MID1 interacting protein 1		ISS	X	24,205,679	24,207,860	RGD:1600115	UniProtKB
G	Mlxipl	MLX interacting protein-like		ISO				RGD:1624291	RGD
G	Nr1h2	nuclear receptor subfamily 1, group H, member 2		ISO	1	95,027,197	95,032,516	RGD:1624291	RGD
G	Nr1h2	nuclear receptor subfamily 1, group H, member 2		IEA	1	95,027,197	95,032,516	RGD:1600115	ENSEMBL
G	Nr1h3	nuclear receptor subfamily 1, group H, member 3		ISO	3	75,542,211	75,550,793	RGD:1624291	RGD
G	Nr1h3	nuclear receptor subfamily 1, group H, member 3		IEA	3	75,542,211	75,550,793	RGD:1600115	ENSEMBL
positive regulation of prostaglandin biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Anxa1	annexin A1		IMP	1	223,478,436	223,494,455	RGD:2306959	RGD
G	Avp	arginine vasopressin		IMP	3	118,205,007	118,206,985	RGD:2300349	RGD
G	Avpr1a	arginine vasopressin receptor 1A		IMP	7	62,225,537	62,229,461	RGD:2300349	RGD
G	Mapk9	mitogen-activated protein kinase 9		IMP	10	35,353,486	35,384,319	RGD:2304243	RGD
G	Pla2g4a	phospholipase A2, group IVA (cytosolic, calcium-dependent)		IMP	13	64,135,729	64,280,815	RGD:1642461	RGD
propionate biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Acss1	acyl-CoA synthetase short-chain family member 1		IDA	3	141,259,016	141,308,871	RGD:2317572	RGD
G	Acss2	acyl-CoA synthetase short-chain family member 2		IDA	3	146,013,995	146,057,119	RGD:2317572	RGD
prostaglandin biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Cd74	Cd74 molecule, major histocompatibility complex, class II invariant chain		ISO	18	56,756,511	56,765,711	RGD:1624291	RGD
G	Cd74	Cd74 molecule, major histocompatibility complex, class II invariant chain		ISS	18	56,756,511	56,765,711	RGD:1600115	UniProtKB
G	Edn1	endothelin 1		ISO	17	28,303,886	28,309,775	RGD:1624291	RGD
G	Edn1	endothelin 1		IEA	17	28,303,886	28,309,775	RGD:1600115	ENSEMBL
G	Edn2	endothelin 2		ISO	5	140,742,686	140,747,580	RGD:1624291	RGD
G	Edn2	endothelin 2		ISO	5	140,742,686	140,747,580	RGD:1624291	RGD
G	Edn2	endothelin 2		IEA	5	140,742,686	140,747,580	RGD:1600115	ENSEMBL
G	Edn2	endothelin 2		IEA	5	140,742,686	140,747,580	RGD:1600115	ENSEMBL
G	Fam213b	family with sequence similarity 213, member B		ISO	5	171,704,247	171,706,850	RGD:1624291	RGD
G	Fam213b	family with sequence similarity 213, member B		ISS	5	171,704,247	171,706,850	RGD:1600115	UniProtKB
G	Hpgds	hematopoietic prostaglandin D synthase		TAS	4	94,611,607	94,636,147	RGD:68838	RGD
G	Mif	macrophage migration inhibitory factor (glycosylation-inhibiting factor)		ISO	20	13,191,986	13,192,851	RGD:1624291	RGD
G	Pla2g4f	phospholipase A2, group IVF		ISO	3	106,786,813	106,800,543	RGD:1624291	RGD
G	Pla2g4f	phospholipase A2, group IVF		IEA	3	106,786,813	106,800,543	RGD:1600115	ENSEMBL
G	Pnpla8	patatin-like phospholipase domain containing 8		IEA	6	63,644,462	63,676,544	RGD:1600115	ENSEMBL
G	Pnpla8	patatin-like phospholipase domain containing 8		ISO	6	63,644,462	63,676,544	RGD:1624291	RGD
G	Ptgds	prostaglandin D2 synthase (brain)		ISO	3	3,632,683	3,635,617	RGD:1624291	RGD
G	Ptgds	prostaglandin D2 synthase (brain)		ISO	3	3,632,683	3,635,617	RGD:1624291	RGD
G	Ptgds	prostaglandin D2 synthase (brain)		IDA	3	3,632,683	3,635,617		UniProtKB
G	Ptges	prostaglandin E synthase		TAS	3	9,946,194	9,957,538	RGD:67929	RGD
G	Ptges	prostaglandin E synthase		IDA	3	9,946,194	9,957,538	RGD:67929	RGD
G	Ptges	prostaglandin E synthase		ISO	3	9,946,194	9,957,538	RGD:1624291	RGD
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		ISO	7	1,351,206	1,368,857	RGD:1624291	RGD
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		IMP	7	1,351,206	1,368,857	RGD:5688071	RGD
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		IDA	7	1,351,206	1,368,857	RGD:5688071	RGD
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		ISO	7	1,351,206	1,368,857	RGD:1624291	RGD
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		IEA	7	1,351,206	1,368,857	RGD:1600115	UniPathway
G	Ptges3	prostaglandin E synthase 3 (cytosolic)		ISS	7	1,351,206	1,368,857	RGD:1600115	UniProtKB
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		TAS	3	158,356,878	158,387,984	RGD:727270	RGD
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		IDA	3	158,356,878	158,387,984	RGD:1580667	RGD
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		IEA	3	158,356,878	158,387,984	RGD:1600115	ENSEMBL
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		ISO	3	158,356,878	158,387,984	RGD:1624291	RGD
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		ISO	3	158,356,878	158,387,984	RGD:1624291	RGD
G	Ptgis	prostaglandin I2 (prostacyclin) synthase		ISS	3	158,356,878	158,387,984	RGD:1600115	UniProtKB
G	Ptgs1	prostaglandin-endoperoxide synthase 1		TAS	3	15,343,832	15,365,412	RGD:1299132	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1		IMP	3	15,343,832	15,365,412	RGD:2300259	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1		ISO	3	15,343,832	15,365,412	RGD:1624291	RGD
G	Ptgs1	prostaglandin-endoperoxide synthase 1		IEA	3	15,343,832	15,365,412	RGD:1600115	UniPathway
G	Ptgs1	prostaglandin-endoperoxide synthase 1		ISS	3	15,343,832	15,365,412	RGD:1600115	UniProtKB
G	Ptgs2	prostaglandin-endoperoxide synthase 2		TAS	13	64,427,288	64,432,978	RGD:619537	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		IMP	13	64,427,288	64,432,978	RGD:2300259	RGD
G	Ptgs2	prostaglandin-endoperoxide synthase 2		ISO	13	64,427,288	64,432,978	RGD:1624291	RGD
G	Tbxas1	thromboxane A synthase 1, platelet		IEA	4	66,502,253	66,677,538	RGD:1600115	UniProtKB
regulation of fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Pdk4	pyruvate dehydrogenase kinase, isozyme 4		ISO	4	30,235,296	30,245,298	RGD:1624291	RGD
G	Pdk4	pyruvate dehydrogenase kinase, isozyme 4		IEA	4	30,235,296	30,245,298	RGD:1600115	ENSEMBL
G	Pdk4	pyruvate dehydrogenase kinase, isozyme 4		ISS	4	30,235,296	30,245,298	RGD:1600115	UniProtKB
G	Pdk4	pyruvate dehydrogenase kinase, isozyme 4		ISS	4	30,235,296	30,245,298	RGD:1600115	UniProtKB
G	Scap	SREBF chaperone		ISO	8	114,706,479	114,761,342	RGD:1624291	RGD
G	Scap	SREBF chaperone		IEA	8	114,706,479	114,761,342	RGD:1600115	ENSEMBL
short-chain fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Oxsm	3-oxoacyl-ACP synthase, mitochondrial		ISO	15	10,761,610	10,765,356	RGD:1624291	RGD
G	Oxsm	3-oxoacyl-ACP synthase, mitochondrial		IEA	15	10,761,610	10,765,356	RGD:1600115	ENSEMBL
unsaturated fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Decr2	2,4-dienoyl CoA reductase 2, peroxisomal		ISO	10	15,350,593	15,358,640	RGD:1624291	RGD
G	Decr2	2,4-dienoyl CoA reductase 2, peroxisomal		IEA	10	15,350,593	15,358,640	RGD:1600115	ENSEMBL
G	Fads1	fatty acid desaturase 1		IDA	1	212,670,792	212,685,718	RGD:632758	RGD
G	Fads1	fatty acid desaturase 1		ISO	1	212,670,792	212,685,718	RGD:1624291	RGD
G	Fads1	fatty acid desaturase 1		IEA	1	212,670,792	212,685,718	RGD:1600115	UniPathway
G	Fads2	fatty acid desaturase 2		IEA	1	212,512,691	212,542,622	RGD:1600115	UniPathway
very long-chain fatty acid biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Elovl1	ELOVL fatty acid elongase 1		ISO	5	138,909,438	138,912,186	RGD:1624291	RGD
G	Elovl1	ELOVL fatty acid elongase 1		ISO	5	138,909,438	138,912,186	RGD:1624291	RGD
G	Elovl1	ELOVL fatty acid elongase 1		IEA	5	138,909,438	138,912,186	RGD:1600115	ENSEMBL
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		IEA	17	29,492,349	29,532,622	RGD:1600115	ENSEMBL
G	Elovl2	ELOVL fatty acid elongase 2		IEA	17	29,492,349	29,532,622	RGD:1600115	ENSEMBL
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl2	ELOVL fatty acid elongase 2		ISO	17	29,492,349	29,532,622	RGD:1624291	RGD
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		IEA	1	251,351,908	251,355,736	RGD:1600115	ENSEMBL
G	Elovl3	ELOVL fatty acid elongase 3		ISO	1	251,351,908	251,355,736	RGD:1624291	RGD
G	Elovl4	ELOVL fatty acid elongase 4		ISO	8	88,855,155	88,881,703	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISO	8	82,922,551	82,948,348	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		ISO	8	82,922,551	82,948,348	RGD:1624291	RGD
G	Elovl5	ELOVL fatty acid elongase 5		IDA	8	82,922,551	82,948,348		UniProtKB
G	Elovl7	ELOVL fatty acid elongase 7		ISO	2	39,568,590	39,596,055	RGD:1624291	RGD
G	Elovl7	ELOVL fatty acid elongase 7		ISO	2	39,568,590	39,596,055	RGD:1624291	RGD
G	Elovl7	ELOVL fatty acid elongase 7		IEA	2	39,568,590	39,596,055	RGD:1600115	ENSEMBL
G	Fads2	fatty acid desaturase 2		TAS	1	212,512,691	212,542,622	RGD:70542	RGD
G	Tecr	trans-2,3-enoyl-CoA reductase		ISO	19	26,232,602	26,259,289	RGD:1624291	RGD
G	Tecr	trans-2,3-enoyl-CoA reductase		ISS	19	26,232,602	26,259,289	RGD:1600115	UniProtKB
wax biosynthetic process
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Awat2	acyl-CoA wax alcohol acyltransferase 2		ISO	X	88,395,929	88,404,189	RGD:1624291	RGD
G	Awat2	acyl-CoA wax alcohol acyltransferase 2		IEA	X	88,395,929	88,404,189	RGD:1600115	ENSEMBL
G	Far1	fatty acyl CoA reductase 1		ISO	1	171,379,992	171,437,818	RGD:1624291	RGD
G	Far1	fatty acyl CoA reductase 1		IEA	1	171,379,992	171,437,818	RGD:1600115	ENSEMBL

Term paths to the root

Path 1
Term	Annotations
biological_process	135981
cellular process	85166
cellular metabolic process	30418
cellular lipid metabolic process	1963
fatty acid metabolic process	748
fatty acid biosynthetic process	269
butyryl-CoA biosynthetic process +	0
fatty acid elongation +	38
lipoate biosynthetic process	2
long-chain fatty acid biosynthetic process +	7
medium-chain fatty acid biosynthetic process	2
methionine catabolic process to 3-methylthiopropanoate	0
mycolic acid biosynthetic process	0
negative regulation of fatty acid biosynthetic process +	19
oxylipin biosynthetic process +	0
positive regulation of fatty acid biosynthetic process +	20
regulation of fatty acid biosynthetic process +	45
short-chain fatty acid biosynthetic process +	6
unsaturated fatty acid biosynthetic process +	97
very long-chain fatty acid biosynthetic process	23
wax biosynthetic process	4
Path 2
Term	Annotations
biological_process	135981
metabolic process	36384
single-organism metabolic process	7985
small molecule metabolic process	5089
organic acid metabolic process	2255
oxoacid metabolic process	2224
carboxylic acid metabolic process	2113
monocarboxylic acid metabolic process	1058
monocarboxylic acid biosynthetic process	369
fatty acid biosynthetic process	269
butyryl-CoA biosynthetic process +	0
fatty acid elongation +	38
lipoate biosynthetic process	2
long-chain fatty acid biosynthetic process +	7
medium-chain fatty acid biosynthetic process	2
methionine catabolic process to 3-methylthiopropanoate	0
mycolic acid biosynthetic process	0
negative regulation of fatty acid biosynthetic process +	19
oxylipin biosynthetic process +	0
positive regulation of fatty acid biosynthetic process +	20
regulation of fatty acid biosynthetic process +	45
short-chain fatty acid biosynthetic process +	6
unsaturated fatty acid biosynthetic process +	97
very long-chain fatty acid biosynthetic process	23
wax biosynthetic process	4