negative regulation of protein kinase activity - Ontology Report

Help | FTP Download | Citing RGD | Contact Us

Keyword

ONTOLOGY REPORT - ANNOTATIONS

Term:	negative regulation of protein kinase activity	go back to main search page
Accession:	GO:0006469	browse the term
Definition:	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
Synonyms:	exact_synonym:	down regulation of protein kinase activity; downregulation of protein kinase activity
	narrow_synonym:	inhibition of protein kinase activity

Rat
Mouse
Human
All
show annotations for term's descendants
Sort by:

negative regulation of protein kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Adora2a	adenosine A2a receptor		IDA	20	13,815,719	13,834,131	RGD:1625697	RGD
G	Akt1	v-akt murine thymoma viral oncogene homolog 1		ISO	6	137,640,482	137,657,552	RGD:1624291	RGD
G	Akt1	v-akt murine thymoma viral oncogene homolog 1		IDA	6	137,640,482	137,657,552		BHF-UCL
G	Akt1s1	AKT1 substrate 1 (proline-rich)		IEA	1	95,325,272	95,328,510	RGD:1600115	ENSEMBL
G	Akt1s1	AKT1 substrate 1 (proline-rich)		ISO	1	95,325,272	95,328,510	RGD:1624291	RGD
G	Cav3	caveolin 3		ISO	4	148,294,428	148,310,380	RGD:1624291	RGD
G	Cdkn2a	cyclin-dependent kinase inhibitor 2A		ISO	5	108,908,749	108,916,380	RGD:1624291	RGD
G	Chp	calcium binding protein p22		IDA	3	106,066,389	106,101,635		UniProtKB
G	Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2		ISO	3	155,509,140	155,511,899	RGD:1624291	RGD
G	Deptor	DEP domain containing MTOR-interacting protein		IEA	7	91,675,825	91,742,576	RGD:1600115	ENSEMBL
G	Deptor	DEP domain containing MTOR-interacting protein		ISO	7	91,675,825	91,742,576	RGD:1624291	RGD
G	Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3		IEA	10	10,984,721	11,009,374	RGD:1600115	ENSEMBL
G	Dnaja3	DnaJ (Hsp40) homolog, subfamily A, member 3		ISO	10	10,984,721	11,009,374	RGD:1624291	RGD
G	Drd1	dopamine receptor D1		IMP	17	16,655,926	16,658,161	RGD:1581394	RGD
G	Drd5	dopamine receptor D5		IMP	14	77,768,060	77,769,487	RGD:1581394	RGD
G	Dus2l	dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)		ISO	19	35,858,496	35,901,661	RGD:1624291	RGD
G	Dusp19	dual specificity phosphatase 19		ISO	3	63,473,333	63,485,843	RGD:1624291	RGD
G	Dvl1	dishevelled segment polarity protein 1		ISO	5	172,705,951	172,717,626	RGD:1624291	RGD
G	Dvl1	dishevelled segment polarity protein 1		IEA	5	172,705,951	172,717,626	RGD:1600115	ENSEMBL
G	Epha1	Eph receptor A1		IEA	4	70,127,872	70,142,309	RGD:1600115	ENSEMBL
G	Epha1	Eph receptor A1		ISO	4	70,127,872	70,142,309	RGD:1624291	RGD
G	Fabp4	fatty acid binding protein 4, adipocyte		ISO	2	93,536,133	93,540,734	RGD:1624291	RGD
G	Fabp4	fatty acid binding protein 4, adipocyte		IEA	2	93,536,133	93,540,734	RGD:1600115	ENSEMBL
G	Fgfr1op	Fgfr1 oncogene partner		ISO	1	47,176,365	47,205,468	RGD:1624291	RGD
G	Gadd45a	growth arrest and DNA-damage-inducible, alpha		ISO	4	96,649,941	96,652,243	RGD:1624291	RGD
G	Gadd45a	growth arrest and DNA-damage-inducible, alpha		IEA	4	96,649,941	96,652,243	RGD:1600115	ENSEMBL
G	Gadd45b	growth arrest and DNA-damage-inducible, beta		ISO	7	10,289,073	10,291,102	RGD:1624291	RGD
G	Gadd45b	growth arrest and DNA-damage-inducible, beta		IEA	7	10,289,073	10,291,102	RGD:1600115	ENSEMBL
G	Gadd45g	growth arrest and DNA-damage-inducible, gamma		IEA	17	19,230,896	19,232,641	RGD:1600115	ENSEMBL
G	Gadd45g	growth arrest and DNA-damage-inducible, gamma		ISO	17	19,230,896	19,232,641	RGD:1624291	RGD
G	Gnaq	guanine nucleotide binding protein (G protein), q polypeptide		ISO	1	219,520,998	219,764,401	RGD:1624291	RGD
G	Gnaq	guanine nucleotide binding protein (G protein), q polypeptide		IEA	1	219,520,998	219,764,401	RGD:1600115	ENSEMBL
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Hspb1	heat shock protein 1		ISO	12	21,911,223	21,912,784	RGD:1624291	RGD
G	Il6	interleukin 6		IDA	4	456,799	461,376	RGD:2306941	RGD
G	Ilk	integrin-linked kinase		IMP	1	163,481,299	163,487,550	RGD:2302091	RGD
G	Inpp5k	inositol polyphosphate-5-phosphatase K		ISO	10	62,953,425	62,971,016	RGD:1624291	RGD
G	Itgb1bp1	integrin beta 1 binding protein 1		ISO	6	41,830,110	41,844,514	RGD:1624291	RGD
G	Lrp6	low density lipoprotein receptor-related protein 6		ISO	4	171,337,114	171,444,932	RGD:1624291	RGD
G	Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1		ISO				RGD:1624291	RGD
G	Nck1	NCK adaptor protein 1		ISO	8	105,346,933	105,409,843	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISS	10	65,574,833	65,766,305	RGD:1600115	HGNC
G	Nf2	neurofibromin 2 (merlin)		ISO	14	85,415,142	85,508,807	RGD:1624291	RGD
G	Nf2	neurofibromin 2 (merlin)		ISO	14	85,415,142	85,508,807	RGD:1624291	RGD
G	Nf2	neurofibromin 2 (merlin)		IEA	14	85,415,142	85,508,807	RGD:1600115	ENSEMBL
G	Pdpk1	3-phosphoinositide dependent protein kinase-1		ISO	10	13,329,708	13,394,080	RGD:1624291	RGD
G	Pdpk1	3-phosphoinositide dependent protein kinase-1		IEA	10	13,329,708	13,394,080	RGD:1600115	ENSEMBL
G	Pkia	protein kinase (cAMP-dependent, catalytic) inhibitor alpha		TAS	2	96,524,399	96,548,144	RGD:729428	RGD
G	Pkia	protein kinase (cAMP-dependent, catalytic) inhibitor alpha		ISO	2	96,524,399	96,548,144	RGD:1624291	RGD
G	Pkig	protein kinase inhibitor, gamma		ISO	3	154,568,485	154,635,867	RGD:1624291	RGD
G	Ppm1e	protein phosphatase, Mg2+/Mn2+ dependent, 1E		ISO	10	75,516,706	75,674,452	RGD:1624291	RGD
G	Ppm1e	protein phosphatase, Mg2+/Mn2+ dependent, 1E		IEA	10	75,516,706	75,674,452	RGD:1600115	ENSEMBL
G	Ppm1f	protein phosphatase, Mg2+/Mn2+ dependent, 1F		ISO	11	86,086,968	86,114,278	RGD:1624291	RGD
G	Ppm1f	protein phosphatase, Mg2+/Mn2+ dependent, 1F		ISS	11	86,086,968	86,114,278	RGD:1600115	UniProtKB
G	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit		ISO	4	5,620,992	5,667,438	RGD:1624291	RGD
G	Prkar1a	protein kinase, cAMP-dependent, regulatory, type I, alpha		IEA	10	148,642,200	148,642,454	RGD:1600115	ENSEMBL
G	Prkar1a	protein kinase, cAMP-dependent, regulatory, type I, alpha		ISO	10	148,642,200	148,642,454	RGD:1624291	RGD
G	Prkca	protein kinase C, alpha		ISO	10	97,367,196	97,638,910	RGD:1624291	RGD
G	Prkrip1	Prkr interacting protein 1 (IL11 inducible)		ISO	12	21,586,183	21,604,474	RGD:1624291	RGD
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Ptprc	protein tyrosine phosphatase, receptor type, C		ISO	13	51,246,163	51,357,995	RGD:1624291	RGD
G	Ptprc	protein tyrosine phosphatase, receptor type, C		ISO	13	51,246,163	51,357,995	RGD:1624291	RGD
G	Ptprc	protein tyrosine phosphatase, receptor type, C		ISS	13	51,246,163	51,357,995	RGD:1600115	UniProtKB
G	Rb1	retinoblastoma 1		ISO	15	53,828,881	53,962,099	RGD:1624291	RGD
G	Rb1	retinoblastoma 1		ISS	15	53,828,881	53,962,099	RGD:1600115	UniProtKB
G	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)		ISO	16	6,822,512	6,888,922	RGD:1624291	RGD
G	Taf7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor		IEA	18	30,541,432	30,543,580	RGD:1600115	ENSEMBL
G	Taf7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor		ISO	18	30,541,432	30,543,580	RGD:1624291	RGD
G	Thy1	Thy-1 cell surface antigen		IDA	8	47,027,721	47,031,857		UniProtKB
G	Trib1	tribbles homolog 1 (Drosophila)		ISO	7	96,442,239	96,448,785	RGD:1624291	RGD
G	Trib3	tribbles homolog 3 (Drosophila)		ISS	3	142,664,641	142,670,135	RGD:1600115	UniProtKB
G	Trib3	tribbles homolog 3 (Drosophila)		ISO	3	142,664,641	142,670,135	RGD:1624291	RGD
G	Trib3	tribbles homolog 3 (Drosophila)		ISO	3	142,664,641	142,670,135	RGD:1624291	RGD
G	Trim27	tripartite motif-containing 27		ISO	17	51,192,286	51,204,942	RGD:1624291	RGD
G	Trim27	tripartite motif-containing 27		IEA	17	51,192,286	51,204,942	RGD:1600115	ENSEMBL
G	Tsc2	tuberous sclerosis 2		ISO	10	13,848,210	13,883,189	RGD:1624291	RGD
G	Ubash3b	ubiquitin associated and SH3 domain containing, B		ISO	8	43,992,862	44,135,847	RGD:1624291	RGD
G	Wwtr1	WW domain containing transcription regulator 1		IEA	2	146,713,977	146,831,603	RGD:1600115	ENSEMBL
G	Wwtr1	WW domain containing transcription regulator 1		ISO	2	146,713,977	146,831,603	RGD:1624291	RGD
inactivation of MAPK activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Cav1	caveolin 1, caveolae protein		ISO	4	42,956,102	42,989,057	RGD:1624291	RGD
G	Cav1	caveolin 1, caveolae protein		IEA	4	42,956,102	42,989,057	RGD:1600115	ENSEMBL
G	Dusp1	dual specificity phosphatase 1		IBA	10	16,942,913	16,945,696	RGD:1600115	RefGenome
G	Dusp10	dual specificity phosphatase 10		IBA	13	100,022,421	100,059,539	RGD:1600115	RefGenome
G	Dusp10	dual specificity phosphatase 10		ISO	13	100,022,421	100,059,539	RGD:1624291	RGD
G	Dusp16	dual specificity phosphatase 16		ISO	4	171,620,395	171,667,593	RGD:1624291	RGD
G	Dusp16	dual specificity phosphatase 16		IBA	4	171,620,395	171,667,593	RGD:1600115	RefGenome
G	Dusp19	dual specificity phosphatase 19		ISO	3	63,473,333	63,485,843	RGD:1624291	RGD
G	Dusp19	dual specificity phosphatase 19		IEA	3	63,473,333	63,485,843	RGD:1600115	ENSEMBL
G	Dusp2	dual specificity phosphatase 2		IBA	3	114,838,605	114,840,790	RGD:1600115	RefGenome
G	Dusp3	dual specificity phosphatase 3		ISO	10	91,031,206	91,044,858	RGD:1624291	RGD
G	Dusp3	dual specificity phosphatase 3		IBA	10	91,031,206	91,044,858	RGD:1600115	GOC
G	Dusp4	dual specificity phosphatase 4		IBA	16	61,109,626	61,119,981	RGD:1600115	RefGenome
G	Dusp5	dual specificity phosphatase 5		IBA	1	259,754,234	259,767,645	RGD:1600115	RefGenome
G	Dusp6	dual specificity phosphatase 6		ISO	7	36,893,264	36,897,494	RGD:1624291	RGD
G	Dusp6	dual specificity phosphatase 6		IBA	7	36,893,264	36,897,494	RGD:1600115	RefGenome
G	Dusp7	dual specificity phosphatase 7		IBA	8	111,510,358	111,515,989	RGD:1600115	RefGenome
G	Dusp9	dual specificity phosphatase 9		ISO	X	159,538,012	159,541,937	RGD:1624291	RGD
G	Dusp9	dual specificity phosphatase 9		IBA	X	159,538,012	159,541,937	RGD:1600115	RefGenome
G	Lax1	lymphocyte transmembrane adaptor 1		ISO	13	46,606,072	46,616,628	RGD:1624291	RGD
G	Lax1	lymphocyte transmembrane adaptor 1		IEA	13	46,606,072	46,616,628	RGD:1600115	ENSEMBL
G	Prkca	protein kinase C, alpha		ISO	10	97,367,196	97,638,910	RGD:1624291	RGD
G	Spred1	sprouty-related, EVH1 domain containing 1		ISO	3	103,184,312	103,246,353	RGD:1624291	RGD
G	Spred1	sprouty-related, EVH1 domain containing 1		IEA	3	103,184,312	103,246,353	RGD:1600115	ENSEMBL
G	Spred2	sprouty-related, EVH1 domain containing 2		ISO	14	100,775,869	100,797,717	RGD:1624291	RGD
G	Spred2	sprouty-related, EVH1 domain containing 2		IEA	14	100,775,869	100,797,717	RGD:1600115	ENSEMBL
G	Spred3	sprouty-related, EVH1 domain containing 3		IEA	1	84,295,411	84,303,809	RGD:1600115	ENSEMBL
G	Spred3	sprouty-related, EVH1 domain containing 3		ISO	1	84,295,411	84,303,809	RGD:1624291	RGD
inactivation of MAPKK activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Igf1r	insulin-like growth factor 1 receptor		ISO	1	122,704,976	122,990,007	RGD:1624291	RGD
G	Igf1r	insulin-like growth factor 1 receptor		ISS	1	122,704,976	122,990,007	RGD:1600115	UniProtKB
negative regulation of brain-derived neurotrophic factor-activated receptor activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Fam72a	family with sequence similarity 72, member A		IDA	13	44,453,797	44,469,514		MGI
negative regulation of cAMP-dependent protein kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Sirt1	sirtuin 1		IEA	20	25,675,302	25,686,494	RGD:1600115	ENSEMBL
G	Sirt1	sirtuin 1		ISO	20	25,675,302	25,686,494	RGD:1624291	RGD
negative regulation of cyclin-dependent protein serine/threonine kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Apc	adenomatous polyposis coli		ISO	18	26,732,147	26,790,383	RGD:1624291	RGD
G	Apc	adenomatous polyposis coli		IEA	18	26,732,147	26,790,383	RGD:1600115	ENSEMBL
G	Apc	adenomatous polyposis coli		ISS	18	26,732,147	26,790,383	RGD:1600115	UniProtKB
G	Casp3	caspase 3		ISO	16	48,944,226	48,962,420	RGD:1624291	RGD
G	Cdk5rap1	CDK5 regulatory subunit associated protein 1		ISO	3	144,803,213	144,840,056	RGD:1624291	RGD
G	Cdk5rap1	CDK5 regulatory subunit associated protein 1		ISS	3	144,803,213	144,840,056	RGD:1600115	UniProtKB
G	Cdkn1a	cyclin-dependent kinase inhibitor 1A		ISO	20	7,376,325	7,386,778	RGD:1624291	RGD
G	Cdkn1a	cyclin-dependent kinase inhibitor 1A		IEA	20	7,376,325	7,386,778	RGD:1600115	ENSEMBL
G	Cdkn1b	cyclin-dependent kinase inhibitor 1B		ISO	4	171,841,705	171,846,506	RGD:1624291	RGD
G	Cdkn1b	cyclin-dependent kinase inhibitor 1B		IEA	4	171,841,705	171,846,506	RGD:1600115	ENSEMBL
G	Cdkn2a	cyclin-dependent kinase inhibitor 2A		ISO	5	108,908,749	108,916,380	RGD:1624291	RGD
G	Cdkn2a	cyclin-dependent kinase inhibitor 2A		ISO	5	108,908,749	108,916,380	RGD:1624291	RGD
G	Hexim1	hexamethylene bis-acetamide inducible 1		ISO	10	92,290,289	92,292,401	RGD:1624291	RGD
G	Hexim1	hexamethylene bis-acetamide inducible 1		ISS	10	92,290,289	92,292,401	RGD:1600115	UniProtKB
G	Hexim2	hexamethylene bis-acetamide inducible 2		IEA	10	92,306,494	92,312,256	RGD:1600115	ENSEMBL
G	Hexim2	hexamethylene bis-acetamide inducible 2		ISO	10	92,306,494	92,312,256	RGD:1624291	RGD
G	Lats1	large tumor suppressor kinase 1		ISO	1	2,375,233	2,383,106	RGD:1624291	RGD
G	Lats1	large tumor suppressor kinase 1		IEA	1	2,375,233	2,383,106	RGD:1600115	ENSEMBL
G	Lats2	large tumor suppressor 2		ISO	15	36,720,000	36,761,065	RGD:1624291	RGD
G	Men1	multiple endocrine neoplasia I		ISO	1	209,114,987	209,120,837	RGD:1624291	RGD
G	Myocd	myocardin		ISO	10	51,496,223	51,588,226	RGD:1624291	RGD
G	Myocd	myocardin		IEA	10	51,496,223	51,588,226	RGD:1600115	ENSEMBL
G	Nr2f2	nuclear receptor subfamily 2, group F, member 2		ISO	1	125,280,974	125,286,929	RGD:1624291	RGD
G	Nr2f2	nuclear receptor subfamily 2, group F, member 2		IEA	1	125,280,974	125,286,929	RGD:1600115	ENSEMBL
G	Plk1	polo-like kinase 1		ISO	1	181,002,811	181,012,741	RGD:1624291	RGD
G	Tfap4	transcription factor AP-4		IEA	10	11,144,057	11,159,763	RGD:1600115	ENSEMBL
G	Tfap4	transcription factor AP-4		ISO	10	11,144,057	11,159,763	RGD:1624291	RGD
G	Wee2	WEE1 homolog 2 (S. pombe)		ISO	4	67,997,589	68,021,263	RGD:1624291	RGD
negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Pten	phosphatase and tensin homolog		ISO	1	236,771,027	236,837,261	RGD:1624291	RGD
G	Pten	phosphatase and tensin homolog		IEA	1	236,771,027	236,837,261	RGD:1600115	ENSEMBL
negative regulation of epidermal growth factor-activated receptor activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		IEA	1	79,091,412	79,108,189	RGD:1600115	ENSEMBL
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		ISO	1	79,091,412	79,108,189	RGD:1624291	RGD
G	Errfi1	ERBB receptor feedback inhibitor 1		ISO	5	168,012,683	168,025,963	RGD:1624291	RGD
G	Errfi1	ERBB receptor feedback inhibitor 1		ISS	5	168,012,683	168,025,963	RGD:1600115	UniProtKB
G	Errfi1	ERBB receptor feedback inhibitor 1		ISS	5	168,012,683	168,025,963	RGD:1600115	UniProtKB
G	Errfi1	ERBB receptor feedback inhibitor 1		ISS	5	168,012,683	168,025,963	RGD:1600115	UniProtKB
G	Errfi1	ERBB receptor feedback inhibitor 1		IDA	5	168,012,683	168,025,963		UniProtKB
G	Errfi1	ERBB receptor feedback inhibitor 1		ISO	5	168,012,683	168,025,963	RGD:1624291	RGD
G	Psen1	presenilin 1		ISO	6	107,737,543	107,776,357	RGD:1624291	RGD
G	Psen1	presenilin 1		IEA	6	107,737,543	107,776,357	RGD:1600115	ENSEMBL
G	Psen2	presenilin 2		ISO	13	95,934,674	95,951,836	RGD:1624291	RGD
G	Socs4	suppressor of cytokine signaling 4		IEA	15	23,229,083	23,243,568	RGD:1600115	ENSEMBL
G	Socs4	suppressor of cytokine signaling 4		ISO	15	23,229,083	23,243,568	RGD:1624291	RGD
G	Socs5	suppressor of cytokine signaling 5		ISO	6	10,552,177	10,582,783	RGD:1624291	RGD
G	Socs5	suppressor of cytokine signaling 5		IEA	6	10,552,177	10,582,783	RGD:1600115	ENSEMBL
G	Zfyve28	zinc finger, FYVE domain containing 28		IEA	14	82,158,573	82,245,071	RGD:1600115	ENSEMBL
G	Zfyve28	zinc finger, FYVE domain containing 28		ISO	14	82,158,573	82,245,071	RGD:1624291	RGD
G	Zgpat	zinc finger, CCCH-type with G patch domain		ISO	3	170,505,701	170,521,996	RGD:1624291	RGD
G	Zgpat	zinc finger, CCCH-type with G patch domain		ISS	3	170,505,701	170,521,996	RGD:1600115	UniProtKB
negative regulation of JUN kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Aida	axin interactor, dorsalization associated		ISO	13	99,339,703	99,357,665	RGD:1624291	RGD
G	Aida	axin interactor, dorsalization associated		IEA	13	99,339,703	99,357,665	RGD:1600115	ENSEMBL
G	Aida	axin interactor, dorsalization associated		IEA	13	99,339,703	99,357,665	RGD:1600115	ENSEMBL
G	Aida	axin interactor, dorsalization associated		ISO	13	99,339,703	99,357,665	RGD:1624291	RGD
G	Dusp10	dual specificity phosphatase 10		ISO	13	100,022,421	100,059,539	RGD:1624291	RGD
G	Dusp10	dual specificity phosphatase 10		IBA	13	100,022,421	100,059,539	RGD:1600115	RefGenome
G	Dusp19	dual specificity phosphatase 19		ISO	3	63,473,333	63,485,843	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Gstp1	glutathione S-transferase pi 1		ISS	1	206,627,398	206,629,866	RGD:1600115	BHF-UCL
G	Hipk3	homeodomain interacting protein kinase 3		ISO	3	89,749,949	89,816,787	RGD:1624291	RGD
G	Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1		IMP	3	76,781,504	76,790,661	RGD:1299562	RGD
G	Pdcd4	programmed cell death 4		ISS	1	260,183,648	260,202,032	RGD:1600115	UniProtKB
G	Sfrp1	secreted frizzled-related protein 1		ISO	16	73,030,458	73,067,304	RGD:1624291	RGD
G	Sfrp1	secreted frizzled-related protein 1		IEA	16	73,030,458	73,067,304	RGD:1600115	ENSEMBL
G	Sfrp2	secreted frizzled-related protein 2		IEA	2	175,479,320	175,486,865	RGD:1600115	ENSEMBL
G	Sfrp2	secreted frizzled-related protein 2		ISO	2	175,479,320	175,486,865	RGD:1624291	RGD
G	Sfrp5	secreted frizzled-related protein 5		ISO	1	248,652,323	248,656,785	RGD:1624291	RGD
G	Sfrp5	secreted frizzled-related protein 5		IEA	1	248,652,323	248,656,785	RGD:1600115	ENSEMBL
G	Tp73	tumor protein p73		ISO	5	170,848,979	171,078,739	RGD:1624291	RGD
G	Tp73	tumor protein p73		IBA	5	170,848,979	171,078,739	RGD:1600115	RefGenome
negative regulation of MAP kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Adipoq	adiponectin, C1Q and collagen domain containing		ISO	11	79,908,291	79,911,065	RGD:1624291	RGD
G	Adipoq	adiponectin, C1Q and collagen domain containing		ISS	11	79,908,291	79,911,065	RGD:1600115	UniProtKB
G	Apoe	apolipoprotein E		ISO	1	79,003,634	79,006,387	RGD:1624291	RGD
G	Apoe	apolipoprotein E		IEA	1	79,003,634	79,006,387	RGD:1600115	ENSEMBL
G	Bmp4	bone morphogenetic protein 4		ISO	15	22,283,171	22,286,757	RGD:1624291	RGD
G	Bmp4	bone morphogenetic protein 4		ISS	15	22,283,171	22,286,757	RGD:1600115	UniProtKB
G	Bmp4	bone morphogenetic protein 4		IEA	15	22,283,171	22,286,757	RGD:1600115	ENSEMBL
G	Bmp7	bone morphogenetic protein 7		ISO	3	163,723,429	163,799,567	RGD:1624291	RGD
G	Bmp7	bone morphogenetic protein 7		IEA	3	163,723,429	163,799,567	RGD:1600115	ENSEMBL
G	Cav1	caveolin 1, caveolae protein		ISO	4	42,956,102	42,989,057	RGD:1624291	RGD
G	Cav3	caveolin 3		ISO	4	148,294,428	148,310,380	RGD:1624291	RGD
G	Cav3	caveolin 3		IEA	4	148,294,428	148,310,380	RGD:1600115	ENSEMBL
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		IEA	1	79,091,412	79,108,189	RGD:1600115	ENSEMBL
G	Cblc	Cbl proto-oncogene, E3 ubiquitin protein ligase C		ISO	1	79,091,412	79,108,189	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISS	3	14,667,700	14,840,625	RGD:1600115	UniProtKB
G	Dusp7	dual specificity phosphatase 7		ISO	8	111,510,358	111,515,989	RGD:1624291	RGD
G	Fem1a	fem-1 homolog a (C. elegans)		ISO				RGD:1624291	RGD
G	Gba	glucosidase, beta, acid		IEA				RGD:1600115	ENSEMBL
G	Gba	glucosidase, beta, acid		ISO				RGD:1624291	RGD
G	Gsk3b	glycogen synthase kinase 3 beta		IMP	11	64,284,731	64,428,698	RGD:2301767	RGD
G	Gstp1	glutathione S-transferase pi 1		ISO	1	206,627,398	206,629,866	RGD:1624291	RGD
G	Hmgcr	3-hydroxy-3-methylglutaryl-CoA reductase		ISO	2	27,127,504	27,149,580	RGD:1624291	RGD
G	Hmgcr	3-hydroxy-3-methylglutaryl-CoA reductase		IEA	2	27,127,504	27,149,580	RGD:1600115	ENSEMBL
G	Hyal2	hyaluronoglucosaminidase 2		ISO	8	112,817,001	112,820,693	RGD:1624291	RGD
G	Hyal2	hyaluronoglucosaminidase 2		IEA	8	112,817,001	112,820,693	RGD:1600115	ENSEMBL
G	Hyal2	hyaluronoglucosaminidase 2		ISS	8	112,817,001	112,820,693	RGD:1600115	UniProtKB
G	Il1b	interleukin 1 beta		ISO	3	116,964,422	116,970,867	RGD:1624291	RGD
G	Il1b	interleukin 1 beta		IEA	3	116,964,422	116,970,867	RGD:1600115	ENSEMBL
G	Inpp5k	inositol polyphosphate-5-phosphatase K		ISO	10	62,953,425	62,971,016	RGD:1624291	RGD
G	Inppl1	inositol polyphosphate phosphatase-like 1		IMP	1	159,278,131	159,292,740	RGD:1626126	RGD
G	Irak3	interleukin-1 receptor-associated kinase 3		IEA	7	59,408,198	59,467,821	RGD:1600115	ENSEMBL
G	Irak3	interleukin-1 receptor-associated kinase 3		ISO	7	59,408,198	59,467,821	RGD:1624291	RGD
G	Irak3	interleukin-1 receptor-associated kinase 3		ISO	7	59,408,198	59,467,821	RGD:1624291	RGD
G	Kng1	kininogen 1		IDA	11	80,109,499	80,131,887	RGD:1600541	RGD
G	Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog		ISO	5	16,933,111	17,054,564	RGD:1624291	RGD
G	Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog		ISS	5	16,933,111	17,054,564	RGD:1600115	UniProtKB
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISO	10	65,574,833	65,766,305	RGD:1624291	RGD
G	Nf1	neurofibromin 1		ISS	10	65,574,833	65,766,305	RGD:1600115	HGNC
G	Nup62	nucleoporin 62		ISO	1	95,288,019	95,303,545	RGD:1624291	RGD
G	Nup62	nucleoporin 62		IEA	1	95,288,019	95,303,545	RGD:1600115	ENSEMBL
G	Prkcd	protein kinase C, delta		ISO	16	5,954,218	5,975,743	RGD:1624291	RGD
G	Prkcd	protein kinase C, delta		IEA	16	5,954,218	5,975,743	RGD:1600115	ENSEMBL
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		ISO	4	160,843,699	160,868,856	RGD:1624291	RGD
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		ISO	4	160,843,699	160,868,856	RGD:1624291	RGD
G	Ptpn6	protein tyrosine phosphatase, non-receptor type 6		IEA	4	160,843,699	160,868,856	RGD:1600115	ENSEMBL
G	Ptprj	protein tyrosine phosphatase, receptor type, J		ISO	3	74,796,764	74,935,540	RGD:1624291	RGD
G	Ptprj	protein tyrosine phosphatase, receptor type, J		ISO	3	74,796,764	74,935,540	RGD:1624291	RGD
G	Rgs14	regulator of G-protein signaling 14		ISO	17	15,293,100	15,307,162	RGD:1624291	RGD
G	Rgs14	regulator of G-protein signaling 14		ISS	17	15,293,100	15,307,162	RGD:1600115	UniProtKB
G	Rgs2	regulator of G-protein signaling 2		ISO	13	57,891,849	57,894,452	RGD:1624291	RGD
G	Rgs2	regulator of G-protein signaling 2		IEA	13	57,891,849	57,894,452	RGD:1600115	ENSEMBL
G	Smpd1	sphingomyelin phosphodiesterase 1, acid lysosomal		ISO	1	163,278,970	163,282,813	RGD:1624291	RGD
G	Smpd1	sphingomyelin phosphodiesterase 1, acid lysosomal		IEA	1	163,278,970	163,282,813	RGD:1600115	ENSEMBL
G	Spry1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)		IEA	2	124,213,692	124,218,334	RGD:1600115	ENSEMBL
G	Spry2	sprouty homolog 2 (Drosophila)		ISO	15	90,009,109	90,011,940	RGD:1624291	RGD
G	Spry2	sprouty homolog 2 (Drosophila)		IEA	15	90,009,109	90,011,940	RGD:1600115	ENSEMBL
G	Spry4	sprouty homolog 4 (Drosophila)		ISO	18	31,532,680	31,547,586	RGD:1624291	RGD
G	Spry4	sprouty homolog 4 (Drosophila)		IEA	18	31,532,680	31,547,586	RGD:1600115	ENSEMBL
G	Tsc2	tuberous sclerosis 2		IMP	10	13,848,210	13,883,189	RGD:1580517	RGD
G	Uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)		ISO	14	44,114,392	44,124,947	RGD:1624291	RGD
G	Uchl1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)		IEA	14	44,114,392	44,124,947	RGD:1600115	ENSEMBL
negative regulation of protein kinase activity by regulation of protein phosphorylation
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Adar	adenosine deaminase, RNA-specific		ISO	2	181,935,246	181,956,039	RGD:1624291	RGD
G	Adar	adenosine deaminase, RNA-specific		IEA	2	181,935,246	181,956,039	RGD:1600115	ENSEMBL
G	Adar	adenosine deaminase, RNA-specific		IEA	2	181,935,246	181,956,039	RGD:1600115	ENSEMBL
G	Adar	adenosine deaminase, RNA-specific		ISS	2	181,935,246	181,956,039	RGD:1600115	UniProtKB
G	Adar	adenosine deaminase, RNA-specific		ISO	2	181,935,246	181,956,039	RGD:1624291	RGD
G	Adar	adenosine deaminase, RNA-specific		ISO	2	181,935,246	181,956,039	RGD:1624291	RGD
G	Adarb1	adenosine deaminase, RNA-specific, B1		ISS	20	11,616,718	11,747,294	RGD:1600115	UniProtKB
G	Adarb1	adenosine deaminase, RNA-specific, B1		ISO	20	11,616,718	11,747,294	RGD:1624291	RGD
G	Npm1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)		ISO	10	18,051,990	18,062,714	RGD:1624291	RGD
G	Npm1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)		ISS	10	18,051,990	18,062,714	RGD:1600115	UniProtKB
G	Ppm1f	protein phosphatase, Mg2+/Mn2+ dependent, 1F		ISO	11	86,086,968	86,114,278	RGD:1624291	RGD
G	Ppm1f	protein phosphatase, Mg2+/Mn2+ dependent, 1F		ISS	11	86,086,968	86,114,278	RGD:1600115	UniProtKB
negative regulation of protein serine/threonine kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Abl1	c-abl oncogene 1, non-receptor tyrosine kinase		ISO	3	10,804,594	10,907,162	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISO	3	14,667,700	14,840,625	RGD:1624291	RGD
G	Dab2ip	DAB2 interacting protein		ISS	3	14,667,700	14,840,625	RGD:1600115	UniProtKB
G	Hspb1	heat shock protein 1		ISO	12	21,911,223	21,912,784	RGD:1624291	RGD
G	Lrp5	low density lipoprotein receptor-related protein 5		ISO	1	206,102,750	206,206,350	RGD:1624291	RGD
G	Lrp6	low density lipoprotein receptor-related protein 6		ISO	4	171,337,114	171,444,932	RGD:1624291	RGD
G	Lrp6	low density lipoprotein receptor-related protein 6		IEA	4	171,337,114	171,444,932	RGD:1600115	ENSEMBL
G	Pkia	protein kinase (cAMP-dependent, catalytic) inhibitor alpha		ISO	2	96,524,399	96,548,144	RGD:1624291	RGD
G	Pkig	protein kinase inhibitor, gamma		ISO	3	154,568,485	154,635,867	RGD:1624291	RGD
G	Pycard	PYD and CARD domain containing		ISO	1	187,276,089	187,277,122	RGD:1624291	RGD
G	Spred1	sprouty-related, EVH1 domain containing 1		ISO	3	103,184,312	103,246,353	RGD:1624291	RGD
G	Spred2	sprouty-related, EVH1 domain containing 2		ISO	14	100,775,869	100,797,717	RGD:1624291	RGD
G	Wnk1	WNK lysine deficient protein kinase 1		IDA	4	156,297,841	156,421,820	RGD:2298791	GOC
negative regulation of protein tyrosine kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Fgfr1op	Fgfr1 oncogene partner		ISO	1	47,176,365	47,205,468	RGD:1624291	RGD
G	Gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1		ISO	10	34,067,237	34,072,593	RGD:1624291	RGD
G	Hyal2	hyaluronoglucosaminidase 2		ISO	8	112,817,001	112,820,693	RGD:1624291	RGD
G	Hyal2	hyaluronoglucosaminidase 2		ISS	8	112,817,001	112,820,693	RGD:1600115	UniProtKB
G	Ibtk	inhibitor of Bruton agammaglobulinemia tyrosine kinase		ISO	8	90,907,477	90,973,991	RGD:1624291	RGD
G	Mvp	major vault protein		ISO	1	186,164,811	186,192,802	RGD:1624291	RGD
G	Ptk6	protein tyrosine kinase 6		IEA	3	170,336,505	170,345,096	RGD:1600115	ENSEMBL
G	Ptk6	protein tyrosine kinase 6		ISO	3	170,336,505	170,345,096	RGD:1624291	RGD
G	Srcin1	SRC kinase signaling inhibitor 1		ISO	10	86,263,255	86,320,681	RGD:1624291	RGD
G	Srcin1	SRC kinase signaling inhibitor 1		ISS	10	86,263,255	86,320,681	RGD:1600115	UniProtKB
negative regulation of Rho-dependent protein serine/threonine kinase activity
	Symbol	Object Name	GBrowse	Evidence	Chr	Start	Stop	Reference	Source
G	Chordc1	cysteine and histidine-rich domain (CHORD)-containing 1		ISO	8	15,732,905	15,759,297	RGD:1624291	RGD
G	Chordc1	cysteine and histidine-rich domain (CHORD)-containing 1		IEA	8	15,732,905	15,759,297	RGD:1600115	ENSEMBL

Term paths to the root

Path 1
Term	Annotations
biological_process	136531
metabolic process	36512
negative regulation of metabolic process	3971
negative regulation of cellular metabolic process	3523
negative regulation of cellular protein metabolic process	797
negative regulation of protein modification process	607
negative regulation of protein phosphorylation	461
negative regulation of protein kinase activity	290
inactivation of MAPKK activity	2
negative regulation of protein histidine kinase activity	0
negative regulation of protein kinase activity by regulation of protein phosphorylation	12
negative regulation of protein serine/threonine kinase activity +	165
negative regulation of protein tyrosine kinase activity +	30
Path 2
Term	Annotations
biological_process	136531
metabolic process	36512
organic substance metabolic process	32846
macromolecule metabolic process	25254
protein metabolic process	10760
regulation of protein metabolic process	3654
regulation of cellular protein metabolic process	3087
regulation of protein modification process	2520
regulation of protein phosphorylation	2008
regulation of protein kinase activity	1097
negative regulation of protein kinase activity	290
inactivation of MAPKK activity	2
negative regulation of protein histidine kinase activity	0
negative regulation of protein kinase activity by regulation of protein phosphorylation	12
negative regulation of protein serine/threonine kinase activity +	165
negative regulation of protein tyrosine kinase activity +	30