ONTOLOGY REPORT - ANNOTATIONS

Term:glycolysis
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Accession:GO:0006096 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of a monosaccharide (generally glucose) into pyruvate, with the concomitant production of a small amount of ATP. Glycolysis begins with phosphorylation of a monosaccharide (generally glucose) on the sixth carbon by a hexokinase, and ends with the production of pyruvate. Pyruvate may be converted to ethanol, lactate, or other small molecules, or fed into the TCA cycle.
Synonyms:exact_synonym: Embden-Meyerhof pathway;   Embden-Meyerhof-Parnas pathway
 related_synonym: anaerobic glycolysis;   modifed Embden-Meyerhof pathway
 alt_id: GO:0019641;   GO:0019642
 xref_analog: MetaCyc:ANAGLYCOLYSIS-PWY;   MetaCyc:GLYCOLYSIS;   MetaCyc:P341-PWY;   MetaCyc:PWY-1042;   MetaCyc:PWY-5484;   Reactome:REACT_100153;   Reactome:REACT_102085;   Reactome:REACT_104018;   Reactome:REACT_104112;   Reactome:REACT_106448;   Reactome:REACT_115767;   Reactome:REACT_1383;   Reactome:REACT_31832;   Reactome:REACT_33061;   Reactome:REACT_33513;   Reactome:REACT_34793;   Reactome:REACT_79118;   Reactome:REACT_80683;   Reactome:REACT_81092;   Reactome:REACT_82178;   Reactome:REACT_88767;   Reactome:REACT_91535;   Reactome:REACT_95821;   Reactome:REACT_96470;   Reactome:REACT_97161;   Reactome:REACT_99760;   Reactome:REACT_99995;   Wikipedia:Glycolysis

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glycolysis term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Aldoa aldolase A, fructose-bisphosphate GBrowse link ISO 1 185,970,658 185,974,615 RGD:1624291 RGD
G Aldoa aldolase A, fructose-bisphosphate GBrowse link ISS 1 185,970,658 185,974,615 RGD:1600115 UniProtKB
G Aldoa aldolase A, fructose-bisphosphate GBrowse link IEA 1 185,970,658 185,974,615 RGD:1600115 UniPathway
G Aldoart2 aldolase 1 A retrogene 2 GBrowse link IEA 6 75,812,016 75,813,706 RGD:1600115 UniPathway
G Aldob aldolase B, fructose-bisphosphate GBrowse link IDA 5 66,283,165 66,296,171 RGD:2302804 RGD
G Aldob aldolase B, fructose-bisphosphate GBrowse link ISO 5 66,283,165 66,296,171 RGD:1624291 RGD
G Aldob aldolase B, fructose-bisphosphate GBrowse link IEA 5 66,283,165 66,296,171 RGD:1600115 UniPathway
G Aldoc aldolase C, fructose-bisphosphate GBrowse link IEA 10 64,308,826 64,312,415 RGD:1600115 UniPathway
G Aldoc aldolase C, fructose-bisphosphate GBrowse link IEA 10 64,308,826 64,312,415 RGD:1600115 InterPro
G Bpgm 2,3-bisphosphoglycerate mutase GBrowse link IEA 4 61,858,884 61,888,007 RGD:1600115 UniProtKB
G Dhtkd1 dehydrogenase E1 and transketolase domain containing 1 GBrowse link IEA 17 83,461,479 83,463,086 RGD:1600115 UniProtKB
G Eno1 enolase 1, (alpha) GBrowse link TAS 5 167,394,131 167,405,516 RGD:1598909 RGD
G Eno1 enolase 1, (alpha) GBrowse link IEA 5 167,394,131 167,405,516 RGD:1600115 UniPathway
G Eno2 enolase 2, gamma, neuronal GBrowse link IDA 4 160,891,003 160,897,723 RGD:2302804 RGD
G Eno2 enolase 2, gamma, neuronal GBrowse link IEA 4 160,891,003 160,897,723 RGD:1600115 UniPathway
G Eno3 enolase 3, beta, muscle GBrowse link IEA 10 57,536,965 57,542,317 RGD:1600115 UniPathway
G Eno4 enolase family member 4 GBrowse link IEA 1 265,466,484 265,489,862 RGD:1600115 InterPro
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 GBrowse link ISO 6 108,439,822 108,469,756 RGD:1624291 RGD
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 GBrowse link IEA 6 108,439,822 108,469,756 RGD:1600115 ENSEMBL
G Entpd5 ectonucleoside triphosphate diphosphohydrolase 5 GBrowse link ISS 6 108,439,822 108,469,756 RGD:1600115 UniProtKB
G Gapdh glyceraldehyde-3-phosphate dehydrogenase GBrowse link IDA 4 161,282,215 161,286,090 RGD:2302804 RGD
G Gapdh glyceraldehyde-3-phosphate dehydrogenase GBrowse link IEA 4 161,282,215 161,286,090 RGD:1600115 UniPathway
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic GBrowse link TAS 1 85,773,751 85,788,290 RGD:1303349 RGD
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic GBrowse link IEA 1 85,773,751 85,788,290 RGD:1600115 UniPathway
G Gck glucokinase GBrowse link IDA 14 86,572,518 86,587,723 RGD:2302790 RGD
G Gck glucokinase GBrowse link IDA 14 86,572,518 86,587,723 RGD:2302851 RGD
G Gpi glucose-6-phosphate isomerase GBrowse link IEA 1 86,658,836 86,686,712 RGD:1600115 UniPathway
G Hk1 hexokinase 1 IDA RGD:2302851 RGD
G Hk1 hexokinase 1 IDA RGD:1358232 RGD
G Hk1 hexokinase 1 IDA RGD:2302804 RGD
G Hk1 hexokinase 1 IEA RGD:1600115 UniProtKB
G Hk2 hexokinase 2 GBrowse link IBA 4 116,925,725 116,975,211 RGD:1600115 RefGenome
G Hk3 hexokinase 3 (white cell) GBrowse link IBA 17 15,651,953 15,669,109 RGD:1600115 RefGenome
G Ldha lactate dehydrogenase A GBrowse link IEA 1 97,403,077 97,412,547 RGD:1600115 UniProtKB
G Ldhb lactate dehydrogenase B GBrowse link IEA 4 180,061,567 180,079,473 RGD:1600115 UniProtKB
G Ldhc lactate dehydrogenase C GBrowse link IEA 1 97,418,622 97,435,275 RGD:1600115 UniProtKB
G LOC100364027 hexokinase 1-like IEA RGD:1600115 UniProtKB
G LOC100365902 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like IEA RGD:1600115 InterPro
G LOC100912010 fructose-bisphosphate aldolase A-like IEA RGD:1600115 InterPro
G LOC688539 similar to Fructose-bisphosphate aldolase A (Muscle-type aldolase) GBrowse link IEA X 119,438,786 119,439,703 RGD:1600115 InterPro
G LOC689343 similar to Pyruvate kinase isozymes M1/M2 (Pyruvate kinase muscle isozyme) GBrowse link IEA 2 130,066,108 130,066,416 RGD:1600115 UniPathway
G Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) GBrowse link IEA 14 87,022,994 87,090,768 RGD:1600115 UniProtKB
G Pdha1 pyruvate dehydrogenase (lipoamide) alpha 1 GBrowse link IEA X 55,899,491 55,913,319 RGD:1600115 InterPro
G Pdha1l1 pyruvate dehydrogenase (lipoamide) alpha 1-like 1 GBrowse link IEA 16 87,959,188 87,961,062 RGD:1600115 InterPro
G Pdha2 pyruvate dehydrogenase (lipoamide) alpha 2 GBrowse link IEA 2 238,983,103 238,984,651 RGD:1600115 InterPro
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 GBrowse link ISO 13 43,624,838 43,652,660 RGD:1624291 RGD
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 GBrowse link ISS 13 43,624,838 43,652,660 RGD:1600115 UniProtKB
G Pfkl phosphofructokinase, liver GBrowse link IDA 20 11,009,359 11,032,511 RGD:2302790 RGD
G Pfkl phosphofructokinase, liver GBrowse link IDA 20 11,009,359 11,032,511 RGD:2301239 RGD
G Pfkl phosphofructokinase, liver GBrowse link IDA 20 11,009,359 11,032,511 RGD:2302851 RGD
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkl phosphofructokinase, liver GBrowse link IDA 20 11,009,359 11,032,511 RGD:2302736 RGD
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkl phosphofructokinase, liver GBrowse link IEA 20 11,009,359 11,032,511 RGD:1600115 UniPathway
G Pfkl phosphofructokinase, liver GBrowse link ISO 20 11,009,359 11,032,511 RGD:1624291 RGD
G Pfkm phosphofructokinase, muscle GBrowse link IDA 7 136,826,122 136,846,040 RGD:1599363 RGD
G Pfkm phosphofructokinase, muscle GBrowse link ISO 7 136,826,122 136,846,040 RGD:1624291 RGD
G Pfkm phosphofructokinase, muscle GBrowse link ISO 7 136,826,122 136,846,040 RGD:1624291 RGD
G Pfkm phosphofructokinase, muscle GBrowse link IDA 7 136,826,122 136,846,040 RGD:2302736 RGD
G Pfkm phosphofructokinase, muscle GBrowse link ISO 7 136,826,122 136,846,040 RGD:1624291 RGD
G Pfkm phosphofructokinase, muscle GBrowse link IEA 7 136,826,122 136,846,040 RGD:1600115 UniPathway
G Pfkp phosphofructokinase, platelet GBrowse link IDA 17 74,760,912 74,823,046 RGD:2302736 RGD
G Pfkp phosphofructokinase, platelet GBrowse link IDA 17 74,760,912 74,823,046 RGD:2302804 RGD
G Pfkp phosphofructokinase, platelet GBrowse link IEA 17 74,760,912 74,823,046 RGD:1600115 UniPathway
G Pgam1 phosphoglycerate mutase 1 (brain) IEA RGD:1600115 UniProtKB
G Pgam2 phosphoglycerate mutase 2 (muscle) GBrowse link ISO 14 86,466,055 86,468,166 RGD:1624291 RGD
G Pgam2 phosphoglycerate mutase 2 (muscle) GBrowse link IEA 14 86,466,055 86,468,166 RGD:1600115 ENSEMBL
G Pgk1 phosphoglycerate kinase 1 GBrowse link IDA X 94,324,219 94,340,193 RGD:2302859 RGD
G Pgk1 phosphoglycerate kinase 1 GBrowse link IMP X 94,324,219 94,340,193 RGD:2302860 RGD
G Pgk1 phosphoglycerate kinase 1 GBrowse link IEA X 94,324,219 94,340,193 RGD:1600115 UniPathway
G Pgk2 phosphoglycerate kinase 2 GBrowse link IEA 9 16,705,747 16,707,313 RGD:1600115 InterPro
G Pklr pyruvate kinase, liver and RBC GBrowse link IDA 2 181,214,853 181,223,505 RGD:2302790 RGD
G Pklr pyruvate kinase, liver and RBC GBrowse link IDA 2 181,214,853 181,223,505 RGD:2302851 RGD
G Pklr pyruvate kinase, liver and RBC GBrowse link IEA 2 181,214,853 181,223,505 RGD:1600115 UniPathway
G Pkm pyruvate kinase, muscle GBrowse link IDA 8 63,486,492 63,508,016 RGD:2302790 RGD
G Pkm pyruvate kinase, muscle GBrowse link ISO 8 63,486,492 63,508,016 RGD:1624291 RGD
G Pkm pyruvate kinase, muscle GBrowse link ISO 8 63,486,492 63,508,016 RGD:1624291 RGD
G Pkm pyruvate kinase, muscle GBrowse link IDA 8 63,486,492 63,508,016 RGD:2302804 RGD
G Pkm pyruvate kinase, muscle GBrowse link IEA 8 63,486,492 63,508,016 RGD:1600115 UniPathway
G Pkm_v1 pyruvate kinase, muscle, variant 1 IEA RGD:1600115 UniPathway
G Pkm_v2 pyruvate kinase, muscle, variant 2 IEA RGD:1600115 UniPathway
G Tpi1 triosephosphate isomerase 1 GBrowse link TAS 4 160,933,341 160,936,871 RGD:1599585 RGD
G Tpi1 triosephosphate isomerase 1 GBrowse link IEA 4 160,933,341 160,936,871 RGD:1600115 UniPathway
negative regulation of glycolysis term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ddit4 DNA-damage-inducible transcript 4 GBrowse link ISO 20 27,252,273 27,254,371 RGD:1624291 RGD
G Ddit4 DNA-damage-inducible transcript 4 GBrowse link IEA 20 27,252,273 27,254,371 RGD:1600115 ENSEMBL
G Fbp1 fructose-1,6-bisphosphatase 1 GBrowse link ISO 17 7,795,717 7,818,041 RGD:1624291 RGD
G Fbp1 fructose-1,6-bisphosphatase 1 GBrowse link ISS 17 7,795,717 7,818,041 RGD:1600115 UniProtKB
G Hdac4 histone deacetylase 4 GBrowse link ISO 9 91,147,435 91,389,810 RGD:1624291 RGD
G Hdac4 histone deacetylase 4 GBrowse link IEA 9 91,147,435 91,389,810 RGD:1600115 ENSEMBL
G Ier3 immediate early response 3 GBrowse link ISO 20 3,076,568 3,077,772 RGD:1624291 RGD
G Ier3 immediate early response 3 GBrowse link IEA 20 3,076,568 3,077,772 RGD:1600115 ENSEMBL
G Ppargc1a peroxisome proliferator-activated receptor gamma, coactivator 1 alpha GBrowse link IMP 14 64,278,115 64,370,912 RGD:7242186 RGD
positive regulation of glycolysis term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Gck glucokinase GBrowse link IDA 14 86,572,518 86,587,723 RGD:2301905 RGD
G Igf1 insulin-like growth factor 1 GBrowse link ISO 7 24,531,669 24,605,742 RGD:1624291 RGD
G Igf1 insulin-like growth factor 1 GBrowse link IEA 7 24,531,669 24,605,742 RGD:1600115 ENSEMBL
G Ins2 insulin 2 GBrowse link ISO 1 202,935,548 202,936,379 RGD:1624291 RGD
G Ins2 insulin 2 GBrowse link ISO 1 202,935,548 202,936,379 RGD:1624291 RGD
G Insr insulin receptor GBrowse link ISO 12 2,934,967 3,087,691 RGD:1624291 RGD
G Insr insulin receptor GBrowse link IEA 12 2,934,967 3,087,691 RGD:1600115 ENSEMBL
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) GBrowse link IMP 20 13,191,986 13,192,851 RGD:1642010 RGD
G Mlxipl MLX interacting protein-like ISO RGD:1624291 RGD
G Mlxipl MLX interacting protein-like ISO RGD:1624291 RGD
G Myc myelocytomatosis oncogene GBrowse link IMP 7 98,953,142 98,958,060 RGD:7207891 RGD
G Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit GBrowse link IDA 2 54,327,821 54,360,462 UniProtKB
G Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit GBrowse link IDA 5 126,007,672 126,074,012 UniProtKB
regulation of glycolysis term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link ISO 6 96,419,024 96,463,891 RGD:1624291 RGD
G Hif1a hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) GBrowse link IEA 6 96,419,024 96,463,891 RGD:1600115 ENSEMBL
G Il3 interleukin 3 GBrowse link ISO 10 39,684,691 39,687,041 RGD:1624291 RGD
G Il3 interleukin 3 GBrowse link IEA 10 39,684,691 39,687,041 RGD:1600115 ENSEMBL
G Mlxipl MLX interacting protein-like IDA RGD:634534 RGD
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase GBrowse link IEA X 89,721,369 89,766,218 RGD:1600115 ENSEMBL
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase GBrowse link ISS X 89,721,369 89,766,218 RGD:1600115 UniProtKB
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase GBrowse link ISO X 89,721,369 89,766,218 RGD:1624291 RGD
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 GBrowse link TAS 17 78,241,182 78,268,272 RGD:729510 RGD
G Pgam1 phosphoglycerate mutase 1 (brain) ISO RGD:1624291 RGD
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit GBrowse link ISO 4 5,620,992 5,667,438 RGD:1624291 RGD
G Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit GBrowse link IEA 4 5,620,992 5,667,438 RGD:1600115 ENSEMBL
regulation of glycolysis by negative regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ncor1 nuclear receptor co-repressor 1 GBrowse link ISO 10 48,481,110 48,628,538 RGD:1624291 RGD
regulation of glycolysis by positive regulation of transcription from RNA polymerase II promoter term browser
Symbol Object Name GBrowse Evidence Chr Start Stop Reference Source
G Ppara peroxisome proliferator activated receptor alpha GBrowse link ISO 7 123,729,774 123,807,090 RGD:1624291 RGD
G Ppara peroxisome proliferator activated receptor alpha GBrowse link IEA 7 123,729,774 123,807,090 RGD:1600115 ENSEMBL
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 136531
    metabolic process 36512
      cellular metabolic process 30527
        generation of precursor metabolites and energy 552
          glycolysis 122
            negative regulation of glycolysis 9
            positive regulation of glycolysis 13
            regulation of glycolysis + 37
Path 2
Term Annotations click to browse term
  biological_process 136531
    metabolic process 36512
      primary metabolic process 29926
        carbohydrate metabolic process 1343
          single-organism carbohydrate metabolic process 1058
            monosaccharide metabolic process 560
              hexose metabolic process 501
                glucose metabolic process 450
                  glucose catabolic process 159
                    glycolysis 122
                      negative regulation of glycolysis 9
                      positive regulation of glycolysis 13
                      regulation of glycolysis + 37
paths to the root

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