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ONTOLOGY REPORT - ANNOTATIONS

Term:classical-complement-pathway C3/C5 convertase complex
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Accession:GO:0005601 term browser browse the term
Definition:A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.


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classical-complement-pathway C3/C5 convertase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2 complement C2 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfb complement factor B part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21254
    cellular anatomical entity 21098
      extracellular space 2149
        classical-complement-pathway C3/C5 convertase complex 2
Path 2
Term Annotations click to browse term
  cellular_component 21254
    cellular anatomical entity 21098
      extracellular region 2692
        extracellular space 2149
          classical-complement-pathway C3/C5 convertase complex 2
paths to the root