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ONTOLOGY REPORT - ANNOTATIONS

Term:extracellularly glutamate-gated ion channel activity
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Accession:GO:0005234 term browser browse the term
Definition:Enables the transmembrane transfer of an ion by a channel that opens when glutamate is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
Comment:Note that this term represents an activity and not a gene product. Consider also annotating to the molecular function term 'glutamate receptor activity ; GO:0008066'.
Synonyms:exact_synonym: extracellular-glutamate-gated ion channel activity


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extracellularly glutamate-gated ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 enables ISO (PMID:14687553) RGD PMID:14687553 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA RGD PMID:1977421 RGD:61622 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 enables ISS
ISO		 GO_REF:0000024
(PMID:28180184)		 UniProt
RGD		 PMID:28180184 GO_REF:0000024 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A contributes_to IMP PMID:9425000 UniProt PMID:9425000 RGD:8554578 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IDA RGD PMID:1350383 RGD:727540 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
extracellularly glutamate-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc17a7 solute carrier family 17 member 7 enables ISO (PMID:19169251) RGD PMID:19169251 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc1a7 solute carrier family 1 member 7 enables ISO (MGI:7294459|PMID:32233906), (MGI:7310191|PMID:16973698) RGD PMID:16973698 PMID:32233906 MGI:7294459 MGI:7310191 NCBI chr 5:122,731,003...122,775,139
Ensembl chr 5:122,731,003...122,775,134 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        monoatomic ion transmembrane transporter activity 752
          monoatomic ion channel activity 457
            ligand-gated monoatomic ion channel activity 183
              extracellular ligand-gated monoatomic ion channel activity 70
                excitatory extracellular ligand-gated monoatomic ion channel activity 38
                  extracellularly glutamate-gated ion channel activity 7
                    extracellularly glutamate-gated chloride channel activity 2
Path 2
Term Annotations click to browse term
  molecular_function 21010
    transporter activity 1259
      transmembrane transporter activity 1163
        passive transmembrane transporter activity 519
          channel activity 519
            gated channel activity 332
              ligand-gated channel activity 187
                ligand-gated monoatomic ion channel activity 183
                  extracellular ligand-gated monoatomic ion channel activity 70
                    excitatory extracellular ligand-gated monoatomic ion channel activity 38
                      extracellularly glutamate-gated ion channel activity 7
                        extracellularly glutamate-gated chloride channel activity 2
paths to the root